lignocaine / Generic mfg. 
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 7 Diseases   124 Trials   124 Trials   723 News 


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  • ||||||||||  tetracycline / Generic mfg., lignocaine / Generic mfg.
    Journal:  Laser-fluorescence assessment of sodium hypochlorite quenching reversal agents on human dentine. (Pubmed Central) -  Jun 9, 2022   
    tramadol is a valid alternative for performing extractions in normal patients or patients allergic to lidocaine. Based on these findings, reversal agents should be employed when assessing the fluorescence of dentine that has been exposed to NaOCl or other quenching agents.
  • ||||||||||  dexamethasone / Generic mfg., dexmedetomidine / Generic mfg.
    Trial completion, Trial completion date, Surgery:  Comparison Of Dexmedetomidine And Dexamethasone As An Adjuvant To Bupivacaine In Brachial Plexus Block (clinicaltrials.gov) -  Jun 1, 2022   
    P=N/A,  N=60, Completed, 
    Articaine may have a better anaesthetic effect compared to lignocaine but the difference may not be clinically relevant. Recruiting --> Completed | Trial completion date: Oct 2021 --> Jan 2022
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Thoracic Epidural Versus General Anaesthesia For Laparoscopic Cholecystectomy: A Randomized Controlled Trial. (Pubmed Central) -  May 24, 2022   
    Administration of intra-articular Ketorolac injection is safe and effective way of achieving postoperative pain relief after arthroscopic knee surgery. Thoracic epidural anaesthesia provides a better alternative to general anaesthesia for Laparoscopic cholecystectomy with lower intraoperative mean arterial blood pressure, 24 hours postoperative consumption of opioids, respiratory complications and length of hospital stay.
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion date, Trial primary completion date:  Intravenous Lidocaine in Total Knee Replacement (clinicaltrials.gov) -  May 18, 2022   
    P4,  N=90, Recruiting, 
    Thoracic epidural anaesthesia provides a better alternative to general anaesthesia for Laparoscopic cholecystectomy with lower intraoperative mean arterial blood pressure, 24 hours postoperative consumption of opioids, respiratory complications and length of hospital stay. Trial completion date: Jul 2021 --> Jul 2023 | Trial primary completion date: Jan 2021 --> Jan 2023
  • ||||||||||  diltiazem / Generic mfg., metronidazole topical / Generic mfg., lidocaine topical / Generic mfg.
    Trial completion, Trial completion date, Trial primary completion date:  Topical Analgesia Post-Haemorrhoidectomy (clinicaltrials.gov) -  May 18, 2022   
    P2/3,  N=192, Completed, 
    Trial completion date: Jul 2021 --> Jul 2023 | Trial primary completion date: Jan 2021 --> Jan 2023 Recruiting --> Completed | Trial completion date: Sep 2022 --> Feb 2022 | Trial primary completion date: Aug 2022 --> Feb 2022
  • ||||||||||  ropivacaine / Generic mfg., lignocaine / Generic mfg.
    Trial completion:  Systemic Effects of Lidocaine Infusion for TAP Block Catheter (clinicaltrials.gov) -  May 17, 2022   
    P=N/A,  N=80, Completed, 
    Not yet recruiting --> Completed Recruiting --> Completed
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Peppering versus Single Injection Technique in Tennis Elbow - A Prospective Comparative Study. (Pubmed Central) -  May 7, 2022   
    In our study we aim to compare the results of injecting steroid and lignocaine mixture via single injection and peppered injection technique and analyse the outcome in each category...On comparison of the 2 groups, there was a significant reduction of VAS scores at 6 months post-injection (p value <0.05) and PRTEE score at 6 weeks, 6 months in peppered injection group. The effects of peppered injection technique is seen to be advantageous over the single injection technique in the management of chronic lateral epicondylitis.
  • ||||||||||  dexamethasone injection / Generic mfg., lignocaine / Generic mfg.
    Journal:  Clinical Assessment of Efficacy of Omega 3 in Oral Submucous Fibrosis Patients - A Randomized Controlled Trial. (Pubmed Central) -  May 6, 2022   
    The effects of peppered injection technique is seen to be advantageous over the single injection technique in the management of chronic lateral epicondylitis. Omega 3 in conjunction with intralesional injections is an effective therapy when compared to intralesional injections alone in treatment of patients with OSMF (grade II and III) with no side effects.
  • ||||||||||  fentanyl citrate / Generic mfg., lignocaine / Generic mfg.
    Journal, Endobronchial ultrasound:  A Survey of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) practices in India. (Pubmed Central) -  May 1, 2022   
    26.1% used cricothyroid lignocaine injection, and the use of 1% or 2% lignocaine for spray-as-you-go administration was similar...There is practice variability in the multiple aspects related technical performance of EBUS-TBNA. Evidence-based guidelines addressing the multiple technical aspects are required to standardize the practice of EBUS-TBNA.
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Buffering lidocaine heightens aversion to cornual nerve injections in dairy calves. (Pubmed Central) -  Apr 29, 2022   
    We detected no treatment differences in heart rate variability measures. These results suggest that cornual nerve blocks are aversive, at least in the short term, and that buffering the lidocaine worsens the calf's response to this procedure.
  • ||||||||||  Vyepti (eptinezumab) / Teva, Lundbeck
    Clinical protocol, Journal:  Status migrainosus inpatient treatment with eptinezumab (SMITE): study protocol for a randomised controlled trial. (Pubmed Central) -  Apr 28, 2022   
    For patients who fail to respond to simple analgesia, triptans and intravenous prochlorperazine or chlorpromazine, there are limited treatment options, and a paucity of high-quality evidence to guide clinical practice...Intravenous lignocaine is an anaesthetic medication used in treatment of status migrainosus, often requiring prolonged admissions and with potential cardiac adverse events...The trial registration number is ACTRN12621001616864. The results of this study will be disseminated through peer-reviewed journals, conference presentations and social media.
  • ||||||||||  lignocaine / Generic mfg.
    Systemic Contact Dermatitis Due to Iodinated Contrast Media () -  Apr 19, 2022 - Abstract #BSACI2022BSACI_169;    
    Skin tests with Lignocaine, Bupivacaine, DepoMedrone, Niopam®, Omnipaque® ( present in both injections ), Visipaque® and Optiray®were performed and were negative in immediate reading...Conclusions We present 2 cases of systemic contact dermatitis due to Omnipaque® and demonstrated high crossreactivity[DR1] . ICM should be avoided in these cases, and alternative tests should be considered.
  • ||||||||||  ketamine / Generic mfg.
    Retrospective data, Journal:  Intravenous Lidocaine and Ketamine Infusions for Headache Disorders: A Retrospective Cohort Study. (Pubmed Central) -  Apr 1, 2022   
    Infusion for medication overuse headache (MOH) led to successful withdrawal of analgesia in 61.1% of lidocaine, and 41.7% of ketamine infusions. Lidocaine and ketamine infusions are an efficacious inpatient treatment for headache disorders, however associated with prolonged length-of-stay and possible side-effects.
  • ||||||||||  NN1213 / Novo Nordisk
    Trial completion date, Trial primary completion date, Surgery:  Randomized Controlled Trial to Assess Blockade of Voltage Gated Sodium Channels During Surgery in Operable Breast Cancer (clinicaltrials.gov) -  Mar 22, 2022   
    P3,  N=1600, Active, not recruiting, 
    Patients undergoing surgery under general anesthesia with endotracheal intubation were benefitted from ketamine nebulization as prophylaxis against moderate-to-severe POST. Trial completion date: Dec 2023 --> Dec 2026 | Trial primary completion date: Dec 2021 --> Oct 2026
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Role of Intralesional Vitamin D3 in the Treatment of Cutaneous Warts. (Pubmed Central) -  Mar 15, 2022   
    Around two to three warts were injected first with 0.2 mL of lignocaine (20 mg/mL)...This is a small sample sized study and lacks a control group. Intralesional vitamin D3 is an effective treatment option for common warts.
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Use of intravenous lignocaine in the perioperative and chronic pain setting. (Pubmed Central) -  Mar 11, 2022   
    Intravenous lignocaine has an emerging role in the treatment of acute pain within the perioperative setting, as recent consensus guidelines from the Association of Anaesthetists have shown. It has played a role in chronic pain management in recent decades, and continues to be a useful tool for pain specialists.
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion, Trial completion date, Trial primary completion date:  Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients (clinicaltrials.gov) -  Feb 16, 2022   
    P=N/A,  N=40, Completed, 
    Suggestions to address these barriers require targeted enabling strategies. Not yet recruiting --> Completed | Trial completion date: Jul 2021 --> Dec 2021 | Trial primary completion date: Jul 2021 --> Nov 2021
  • ||||||||||  lignocaine / Generic mfg.
    Review, Journal:  The what, why and when of wide awake local anaesthesia no tourniquet surgery. (Pubmed Central) -  Feb 15, 2022   
    This technique uses the vasoconstrictive effects of adrenaline and the local anaesthetic effects of lignocaine to establish a Bier block with haemostatic control...This review delves into the current uses of wide awake local anaesthesia no tourniquet surgery, outlining the initial conception of the practice by Canadian surgeons. The advantages and disadvantages are considered, and potential future applications of this technique are discussed.
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Efficacy of external cold and a vibrating device in reducing pain and anxiety during local anaesthesia. (Pubmed Central) -  Feb 10, 2022   
    The control intervention constitutes infiltration of 1.8 mL of 2% lignocaine in addition to 1:100,000 adrenaline (Lox, Neon Laboratories Mumbai, India) whereas, the experimental group used external cold and a vibrating device (Buzzy®, MMJ Labs, Atlanta, GA, USA) in annexation to the control protocol...Lower pain sensation and anxiety was recorded in the experimental group using Buzzy when compared to control. External cold in adjacent with vibrations might be efficient in lowering pain as well as anxiety in children experiencing infiltration dental anaesthesia though further research work is requisite with a larger sample size.