lignocaine / Generic mfg. 
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 7 Diseases   124 Trials   124 Trials   723 News 


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  • ||||||||||  lignocaine / Generic mfg.
    Trial primary completion date:  Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Thoracotomy (clinicaltrials.gov) -  Jun 22, 2023   
    P=N/A,  N=138, Recruiting, 
    As expected, the active surface area and electron transfer processes were accelerated by the modification, resulting in ultra-sensitive quantification with detection limits of 19.00 and 13.94 Trial primary completion date: May 2023 --> May 2024
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Effectiveness of buffered and non-buffered local anaesthetic in inferior alveolar nerve block: A randomised study. (Pubmed Central) -  Jun 19, 2023   
    Subjects were randomised into Groups A and B. Group A received 2 ml of freshly prepared 2% lignocaine with 1:100,000 adrenaline buffered with 0.18 ml of 8.4% sodium bicarbonate solution while those in Group B received non-buffered 2% lignocaine with 1:100,000 adrenaline LA solutions...Pain at the injection site assessed objectively and subjectively were also statistically different (p<0.001). The findings of this study suggest that buffered LA is more effective than non-buffered LA of the same composition when used for IANB particularly concerning a significantly faster rate of onset and less pain at the injection site.
  • ||||||||||  valsartan / Generic mfg., alprazolam / Generic mfg., lignocaine / Generic mfg.
    Journal:  Comprehensive analysis of the diagnostic and therapeutic value of the hypoxia-related gene PLAUR in the progression of atherosclerosis. (Pubmed Central) -  May 31, 2023   
    The DrugMatrix database was used to predict alprazolam, valsartan, biotin A, lignocaine, and curcumin as potential drugs to delay lesion progression by antagonizing PLAUR, and AutoDock was used to verify the binding ability of drugs and PLAUR. Overall, this study provides the first systematic identification of the diagnostic and therapeutic value of PLAUR in AS and offers multiple treatment options with potential applications.
  • ||||||||||  fentanyl citrate / Generic mfg., lignocaine / Generic mfg.
    Journal:  Commentary: Intravenous fentanyl vs. topical lignocaine for ProSeal (Pubmed Central) -  May 5, 2023   
    For clinical practice, we believe that our results indicate that dexmedetomidine should be considered for the prevention of PIA in patients that have previously experienced PIA. No abstract available
  • ||||||||||  lignocaine / Generic mfg.
    A SEASON OF ACUTE KIDNEY INJURY POST BREAST AUGMENTATION () -  Mar 28, 2023 - Abstract #ISNWCN2023ISN_WCN_654;    
    She was given lignocaine 2% as local anaesthesia before receiving 200 mls hyaluronic acid...In this report, dubious qualification of practitioners, sterility of instruments & hyaluronic acids and safety/hygiene of aesthetic facilities all may be linked to the potential systemic intoxication of hyaluronic acid resulting in multiorgan failure as shown in the victims. The authors hope this report will raise the awareness of such malpractice, the potential toxic effects and the serious complications of hyaluronic acid injection.
  • ||||||||||  lignocaine / Generic mfg., levamisole / Generic mfg.
    Journal:  Clinical characteristics of fatal cocaine toxicity in Australia, 2000-2021. (Pubmed Central) -  Mar 24, 2023   
    The authors hope this report will raise the awareness of such malpractice, the potential toxic effects and the serious complications of hyaluronic acid injection. Compared to MDT and TI cases, CO cases had higher cocaine concentrations, higher concentrations of adulterants, higher levels of cardiovascular disease and were more likely to suddenly collapse.
  • ||||||||||  lignocaine / Generic mfg.
    New P2 trial:  Pain Reduction After Separators Placement (clinicaltrials.gov) -  Mar 21, 2023   
    P2,  N=60, Enrolling by invitation, 
  • ||||||||||  lignocaine / Generic mfg.
    Enrollment open, Enrollment change, Trial completion date, Trial primary completion date:  DiaVACCS: Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women. (clinicaltrials.gov) -  Mar 17, 2023   
    P=N/A,  N=1500, Recruiting, 
    Compared to MDT and TI cases, CO cases had higher cocaine concentrations, higher concentrations of adulterants, higher levels of cardiovascular disease and were more likely to suddenly collapse. Completed --> Recruiting | N=1104 --> 1500 | Trial completion date: Dec 2020 --> Dec 2038 | Trial primary completion date: Dec 2020 --> Dec 2038
  • ||||||||||  lignocaine / Generic mfg.
    Enrollment closed:  Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers (clinicaltrials.gov) -  Mar 8, 2023   
    P4,  N=155, Active, not recruiting, 
    Completed --> Recruiting | N=1104 --> 1500 | Trial completion date: Dec 2020 --> Dec 2038 | Trial primary completion date: Dec 2020 --> Dec 2038 Recruiting --> Active, not recruiting
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Lidocaine for Neuropathic Cancer Pain (LiCPain): study protocol for a mixed-methods pilot study. (Pubmed Central) -  Feb 27, 2023   
    The local anaesthetic lidocaine (lignocaine) has the potential to help manage neuropathic cancer-related pain when administered as an extended, continuous subcutaneous infusion...The protocol and Patient Information and Consent Form have been approved by Sydney Local Health District (Concord) Human Research Ethics Committee 2019/ETH07984 and University of Technology Sydney ETH17-1820. ANZCTR ACTRN12617000747325.
  • ||||||||||  digoxin / Generic mfg., furosemide / Generic mfg.
    Trial initiation date:  Intralesional Injection of Combined Digoxin and Furosemide Versus 5-Flurouracil in Plantar Warts (clinicaltrials.gov) -  Feb 21, 2023   
    P=N/A,  N=45, Not yet recruiting, 
    We conclude that the quality of recovery of patients receiving opioid-free methods of anesthesia was not inferior to OA in patients undergoing breast cancer surgeries. Initiation date: Nov 2022 --> Feb 2023
  • ||||||||||  lignocaine / Generic mfg.
    Retrospective data, Review, Journal:  The role of corticosteroid injections in treating plantar fasciitis: A systematic review and meta-analysis. (Pubmed Central) -  Feb 12, 2023   
    Regarding AOFAS score, PRP was more efficacious than CSI at 6 months of follow-up. Only through the development of high-quality, large-scale longitudinal studies, will the findings and conclusions of this meta-analysis be strengthened and influence our clinical practice in the treatment of plantar fasciitis.
  • ||||||||||  lignocaine / Generic mfg.
    Pain in Childhood Workshop () -  Feb 3, 2023 - Abstract #APS2023APS_1;    
    Program This workshop aims to provide clinicians managing persistent pain in young people with updates and practical tips. In our first session, we initially will explore the use of lignocaine infusions in acute and chronic pain conditions in the paediatric setting.This will be followed by discussion and findings from the RAPID study, an international pharmacovigilance research collaborative looking at the effectiveness and adverse effects of medications used in palliative care and pain management.We will then go on to discuss chronic lower limb pain conditions in children and adolescents and have an interactive session with researchers developing guidelines and priorities for its investigation and management.The Workshop will finish with the SIG AGM.
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion, Intubation:  Lignocaine Nebulization Versus Airway Block for Awake Nasal Fiberoptic Intubation in Patients With Head and Neck Burns. (clinicaltrials.gov) -  Feb 2, 2023   
    P=N/A,  N=50, Completed, 
    In our first session, we initially will explore the use of lignocaine infusions in acute and chronic pain conditions in the paediatric setting.This will be followed by discussion and findings from the RAPID study, an international pharmacovigilance research collaborative looking at the effectiveness and adverse effects of medications used in palliative care and pain management.We will then go on to discuss chronic lower limb pain conditions in children and adolescents and have an interactive session with researchers developing guidelines and priorities for its investigation and management.The Workshop will finish with the SIG AGM. Recruiting --> Completed
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  The Comparison of Inflation of Cuff with 1% Propofol, 4% Lignocaine, or 0.9% Saline on Laryngotracheal Morbidity. (Pubmed Central) -  Jan 10, 2023   
    The occurrence of POST was highest in Group A, followed by Group S and Group L, and least in Group P. The hemodynamic parameters were comparable with no statistical difference in all the four groups (P < 0.05). The intracuff 1% propofol is superior to 4% xylocaine and normal saline in the prevention of cough and sore throat postoperatively, whereas inflation of cuff with air leads to maximum incidence of these complications.
  • ||||||||||  metamizole / Generic mfg., morphine sulphate / Generic mfg., lignocaine / Generic mfg.
    Trial completion, Enrollment change, Trial completion date, Trial primary completion date, Surgery:  Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia (clinicaltrials.gov) -  Dec 21, 2022   
    P4,  N=87, Completed, 
    Phase classification: P2 --> P=N/A Suspended --> Completed | N=150 --> 87 | Trial completion date: Feb 2022 --> Jul 2022 | Trial primary completion date: Jan 2022 --> Jun 2022
  • ||||||||||  nystatin oral / Generic mfg., lignocaine / Generic mfg.
    Review, Journal:  Speech pathology prescribing in the outpatient setting: A review of requirements, considerations and barriers. (Pubmed Central) -  Nov 22, 2022   
    The successful implementation of SP-led prescribing was identified to be complex from a legislative and operational perspective, as well as being highly context dependent. This study further highlights the importance of a thorough context evaluation and workflow mapping prior to full-scale implementation of SP prescribing trials.
  • ||||||||||  epinephrine / Generic mfg., lignocaine / Generic mfg.
    Journal:  Minimum volume of infiltrative anesthetic required for pain-free placement of mini-implants: a split-mouth clinical trial. (Pubmed Central) -  Nov 17, 2022   
    1.0 mL of 2% lignocaine with 1:200,000 epinephrine administered submucosally appears to provide better anesthesia than 0.5 mL during and after insertion of mini-implants. This study will help the operator administer the correct volume of infiltrative anesthetic thereby improving pain response, alleviating patient anxiety, and providing a better patient experience during and immediately after mini-implant placement.
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Inadvertent injection of large volume lignocaine during myelography- A Never Event. (Pubmed Central) -  Nov 9, 2022   
    This study will help the operator administer the correct volume of infiltrative anesthetic thereby improving pain response, alleviating patient anxiety, and providing a better patient experience during and immediately after mini-implant placement. No abstract available