lignocaine / Generic mfg. 
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  • ||||||||||  lignocaine / Generic mfg.
    Trial completion date, Trial primary completion date:  Motor Sparing Supraclavicular Block (clinicaltrials.gov) -  May 16, 2024   
    P=N/A,  N=44, Recruiting, 
    Buffered lignocaine is more effective as compared to commercial lignocaine in the extraction of infected teeth. Trial completion date: Feb 2024 --> May 2024 | Trial primary completion date: Feb 2024 --> May 2024
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion, Enrollment change:  Intravenous Lidocaine in Total Knee Replacement (clinicaltrials.gov) -  May 15, 2024   
    P4,  N=62, Completed, 
    Recommending SCIP as standard of care for most patients needing long-term prophylaxis has the potential to transform secondary prophylaxis of ARF/RHD in NZ and globally. Recruiting --> Completed | N=90 --> 62
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion date, Trial primary completion date, Surgery:  IP LIGNO: Analgesic Effect of IntraPeritoneal LIGNOcaine in Gynaecological Open Surgery (clinicaltrials.gov) -  May 8, 2024   
    P=N/A,  N=112, Recruiting, 
    The mean VAS score during procedure was 3.06 for group A and 1.03 for group B. Conclusion The study inferred that topical anesthesia is a better choice in superficial dermatosurgical procedures for providing adequate anesthesia and improved compliance when compared to infiltrative anesthesia. Trial completion date: Apr 2024 --> Dec 2024 | Trial primary completion date: Mar 2024 --> Dec 2024
  • ||||||||||  Review, Journal:  An Exploration of Analgesia Options for Australian Sheep. (Pubmed Central) -  Apr 13, 2024   
    Patients were more comfortable with a statistically significant difference in the comfort score in group III as compared to group II and group I. Dexmedetomidine nebulization in a dose of 1.5 ?g/kg (compared to 1 ?g/kg or 0.5 ?g/kg) as an adjuvant to lignocaine, provides better bronchoscopy conditions and patient satisfaction. Only six analgesic product formulations, namely, lignocaine (e.g., Numocaine
  • ||||||||||  Dynastat (parecoxib) / Pfizer
    Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Accelerated Recovery Following Opioid-free Anaesthesia in Supratentorial Craniotomy (clinicaltrials.gov) -  Apr 8, 2024   
    P=N/A,  N=25, Completed, 
    However, additional research is necessary to ascertain the result of this study. Not yet recruiting --> Completed | N=44 --> 25 | Trial completion date: Sep 2023 --> Jan 2024 | Trial primary completion date: Sep 2023 --> Jan 2024
  • ||||||||||  Journal, Surgery:  Combined segmental spinal epidural for major spine surgery: a case report. (Pubmed Central) -  Apr 3, 2024   
    Trial completion date: Dec 2024 --> Dec 2026 | Trial primary completion date: May 2024 --> May 2026 In lateral position, a T8-T9 epidural catheter was placed, followed by segmental spinal anaesthesia (2.5?mL 0.5% hyperbaric bupivacaine+30?
  • ||||||||||  Maxidex (dexamethasone eye drops, suspension) / Novartis, Ozurdex (dexamethasone intravitreal implant) / AbbVie
    Enrollment open:  Particulate Vs. Non-Particulate Steroid for Sacroiliac Joint Injection (clinicaltrials.gov) -  Mar 28, 2024   
    P4,  N=230, Recruiting, 
    In lateral position, a T8-T9 epidural catheter was placed, followed by segmental spinal anaesthesia (2.5?mL 0.5% hyperbaric bupivacaine+30? Not yet recruiting --> Recruiting
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Comparison of the Efficacy Between Regional Nerve Block and Ring Block as Local Anesthetic Techniques for Platelet-Rich Plasma Treatment. (Pubmed Central) -  Mar 11, 2024   
    In the study group, STN and SON blocks as the regional nerve blocks were given 2% lignocaine with 1:80000 adrenaline to anesthetize the area, and the PRP was injected from the anterior hairline up to the vertex of the scalp, not involving the occipital and temporal regions...The ring block is the common local anesthetic technique used for producing anesthesia, while regional nerve blocks are more effective in producing local anesthesia. This study proves that STN and SON blocks are better anesthetic techniques than the ring block technique for PRP treatment in hair growth.
  • ||||||||||  metamizole / Generic mfg., lignocaine / Generic mfg.
    Journal:  Possibility of Using Surgical Pleth Index in Predicting Postoperative Pain in Patients after Vitrectomy Performed under General Anesthesia. (Pubmed Central) -  Feb 24, 2024   
    The current study proves the feasibility that preoperative SPI values help with predicting IPPP immediately after VRS under AoA guidance and discrimination (between mild diagnoses and IPPP when based on postoperative SPI values) as they correlate with heart rate variations. Specifically, this applies when the countermeasures of IPPP and hemodynamic fluctuations are understood to be of importance in reducing unwelcome adverse events.
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion, Trial completion date, Trial initiation date, Trial primary completion date:  Intra Articular Injection of Ozone With Corticosteroids vs PRGF in Knee Osteoarthritis (clinicaltrials.gov) -  Feb 20, 2024   
    P=N/A,  N=90, Completed, 
    Specifically, this applies when the countermeasures of IPPP and hemodynamic fluctuations are understood to be of importance in reducing unwelcome adverse events. Recruiting --> Completed | Trial completion date: Oct 2023 --> May 2023 | Initiation date: May 2023 --> Jun 2022 | Trial primary completion date: Oct 2023 --> May 2023
  • ||||||||||  Activase (alteplase) / Roche, Boehringer Ingelheim, Kyowa Kirin, Mitsubishi Tanabe
    Journal:  Systematic approach to obtain axillary arterial access for pediatric heart catheterizations. (Pubmed Central) -  Feb 15, 2024   
    We infiltrated per-operatively 2% lignocaine (10?mg) for arterial spasms, long sheaths use (?5?Fr), and ?60?min procedures in <3?kg patients...There were two self-resolving arterial dissections, one sub-occlusive arterial thrombosis (resolved with 6 weeks of enoxaparin), and one occlusive arterial thrombosis (resolved with alteplase thrombolysis and 6 weeks of enoxaparin)...Four patients with complex univentricular hearts died from non-procedural causes at a median of 40 days (IQR, 31-161) postoperative. Systematic approach for AAA is the key to success and unlocks the many potentials of trans-axillary pediatric cardiology interventions.
  • ||||||||||  midazolam hydrochloride / Generic mfg., lignocaine / Generic mfg.
    Enrollment open:  Opioid Free Anesthesia for Laparoscopic Cholecystectomy (clinicaltrials.gov) -  Feb 2, 2024   
    P4,  N=72, Recruiting, 
    Randomization was done to split the population into study and control. Not yet recruiting --> Recruiting