lignocaine / Generic mfg. 
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 7 Diseases   124 Trials   124 Trials   723 News 


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  • ||||||||||  lignocaine / Generic mfg.
    Trial completion date, Trial primary completion date:  Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers (clinicaltrials.gov) -  Oct 2, 2024   
    P=N/A,  N=230, Enrolling by invitation, 
    Trial completion date: Dec 2025 --> Dec 2027 | Trial primary completion date: Dec 2025 --> Dec 2027
  • ||||||||||  midazolam hydrochloride / Generic mfg., lignocaine / Generic mfg.
    Trial completion:  Opioid Free Anesthesia for Laparoscopic Cholecystectomy (clinicaltrials.gov) -  Sep 20, 2024   
    P4,  N=72, Completed, 
    In accordance to our study, 2% lignocaine in 1:2,00,000 dilution of adrenaline can safely be used in minor oral surgical procedures, and is safe in hypertensive and cardiac patients as this dilution does not alter any haemodynamic parameters to a great extent. Recruiting --> Completed
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion:  Lignocaine Versus Sodium Bicarbonate on Reducing Pain During Propofol Injection (clinicaltrials.gov) -  Sep 4, 2024   
    P1,  N=180, Completed, 
    Tetracaine 2% with oxymetazoline 0.05% is a more potent and rapidly acting anaesthetic-decongestant spray than Co-phenylcaine, with a longer duration of action. Recruiting --> Completed
  • ||||||||||  lignocaine / Generic mfg.
    Trial withdrawal:  Effectiveness of dental local analgesia among children for dental extractions (EUDRACT) -  Aug 30, 2024   
    P4,  N=50, Withdrawn, 
    Conclusion ?Intracuff alkalinized lignocaine 1% and 2% were significantly better than saline in reducing coughing and bucking at extubation, post extubation haemodynamic changes and incidence of postoperative cough, sore throat, and dysphonia. Recruiting --> Withdrawn
  • ||||||||||  lignocaine / Generic mfg.
    Trial termination:  effectiveness of local dental anaesthetic in children (EUDRACT) -  Aug 30, 2024   
    P4,  N=150, Terminated, 
    Recruiting --> Withdrawn Recruiting --> Terminated
  • ||||||||||  lignocaine / Generic mfg.
    Journal, Surgery:  Buffered versus Non-buffered Local Anaesthesia in Minor Oral Surgery - A Comparative Study. (Pubmed Central) -  Aug 26, 2024   
    In the study group, patients were given buffered local anaesthesia (which was prepared by mixing 2% lignocaine with 1:80,000 adrenaline and 8.4% sodium bicarbonate) before extraction...The study concludes that buffered local anaesthesia was more beneficial than non-buffered local anaesthesia in reducing pain on injection, providing a quicker onset of local anaesthesia and increasing the duration of action of the local anaesthesia. Buffering is a safe, easy and efficient process and should be routinely followed to provide a better experience to the patients.
  • ||||||||||  lignocaine / Generic mfg.
    Successful fat grafting despite toxicity of lignocaine to adipocytes (Poster Area) -  Aug 5, 2024 - Abstract #EADV2024EADV_3184;    
    It offers a low-cost, effective therapeutic option, especially in cases where other destructive modalities such as bleomycin are contraindicated such as immunosuppression and pregnancy. Despite published evidence of toxicity of lignocaine to adipocytes, the use of lignocaine based tumescent anesthesia in the harvesting and placement of fat can be successfully achieved and Dermatologists need not fear its use in this context.
  • ||||||||||  lignocaine / Generic mfg.
    Toxicity of lignocaine to adipocytes is overstated: successful grafting technique with tumescent anesthesia. (Poster Area) -  Aug 5, 2024 - Abstract #EADV2024EADV_2804;    
    Despite published evidence of toxicity of lignocaine to adipocytes, the use of lignocaine based tumescent anesthesia in the harvesting and placement of fat can be successfully achieved and Dermatologists need not fear its use in this context. Despite published evidence of toxicity of lignocaine to adipocytes, the use of lignocaine based tumescent anesthesia in the harvesting and placement of fat can be successfully achieved and Dermatologists need not fear its use in this context.
  • ||||||||||  epinephrine / Generic mfg.
    Review, Journal:  Reevaluating the epinephrine myth: A comprehensive review. (Pubmed Central) -  Jul 30, 2024   
    Phentolamine serves as a potential rescue agent if vascular compromise occurs. Precautionary measures must be taken when using this combination in high-risk patients.
  • ||||||||||  Management of phantom limb pain in traumatic lower limb amputation (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_1916;    
    Peripheral factors result from abnormal nociceptive input from the residual limb or ectopic discharge from a stump neuroma. Central factors are due to central sensitisation with increased excitability of the dorsal horn neurons, reduction of inhibitory processes and reorganisation of the somatosensory cortex.
  • ||||||||||  triamcinolone acetonide / Generic mfg., lignocaine / Generic mfg.
    Study to assess pain relief and functional outcome after intraarticular sacroiliac joint injection (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_1864;    
    Purpose of this study is to assess the pain relief and functional outcome after fluoroscopic guided intraarticular sacroiliac joint injection of 1cc 1% lignocaine with 1cc 40 mg triamcinolone acetonide in diagnosed cases of sacroiliitis. The fluoroscopic guided intra articular sacroiliac joint injection can be an effective treatment option for patients diagnosed with sacroiliitis, those receiving medical treatment for low backache, and those who have undergone surgery for Low backache without relief.
  • ||||||||||  lignocaine / Generic mfg.
    Pre-emptive Use of Lidocaine Patches Following SCS Implant to Prevent Postoperative Pain and Hyperse (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_1632;    
    The pain wasless intense and manageable with the preemptiveapplication of lignocaine patches.Delayed wound healing was implicated in thelate start of application of patches for twopatients who had IPG site pain at one monthand responded to lidocaine plasters.The concomitant factors necessitating revisionincluded-1.Allergy to lidocaine plasters , hence inabilityto apply2. Lead migrationThese two patients continued to havepersistent IPG site pain after revision surgeryThis is the first reported evaluation of preemptiveapplication of Lidocaine plasters forthe IPG site pain.
  • ||||||||||  Growth Factor Concentrate in Traumatic Peripheral Neuropathy of Ulnar and Median Nerve (Exhibition Hall/Poster Area) -  Jul 18, 2024 - Abstract #IASP2024IASP_854;    
    GFs play important roles in peripheral nerve regeneration, including regulating cellular survival, growth, proliferation, differentiation, migration, neuroinflammation, and neurotrophic factor secretion. At the site of peripheral nerve injury, exogenous local administration of growth factor concentrate derived from platelets, creates microenvironment that supports peripheral nerve repair and regeneration.