 |
7 Diseases |  |
124 Trials |
|
124 Trials |  |
723 News |  |
| «12...234567891011121314» |
- || lignocaine / Generic mfg.
70ms! On lignocaine he had transient CHB! (Twitter) - Jun 1, 2021
- | lignocaine / Generic mfg.
Biomarker, Journal: Role of psychological distress screening in predicting the outcomes of epidural steroid injection in chronic low back pain. (Pubmed Central) - May 29, 2021
Fluoroscopic caudal epidural steroid injection comprising 80 mg methylprednisolone and 8 mg of lignocaine was performed...Psychological distress may predict response only in certain outcome measures in patients suffering from nonspecific CLBP. If the interest lied primarily in pain and functional improvement, the psychological distress failed to discriminate the results at 6 months.
- ||| lignocaine / Generic mfg.
That’s for the carpal tunnel surgeons. I use 5ml 1% Lignocaine and 5ml 0.5% Marcaine. Can’t be using multiple stickers. (Twitter) - May 28, 2021
- || epinephrine / Generic mfg., lignocaine / Generic mfg.
Clinical, Journal: Safety and efficacy of intracameral mydriatics: Lignocaine and epinephrine in manual small-incision cataract surgery and their effect on blood pressure and heart rate. (Pubmed Central) - May 28, 2021
If the interest lied primarily in pain and functional improvement, the psychological distress failed to discriminate the results at 6 months. No abstract available
- | lignocaine / Generic mfg.
Journal: Anaesthesia for Awake Fiberoptic Intubation: Ultrasound-Guided Airway Nerve Block versus Ultrasonic Nebulisation with Lignocaine. (Pubmed Central) - May 27, 2021
No abstract available This study shows that significant lesser time required for performing awake fiberoptic intubation when patient received ultrasound guided airway nerve block in comparison to ultrasonic nebulisation for airway anaesthesia.
- || fentanyl citrate / Generic mfg., lignocaine / Generic mfg.
Clinical, Journal: Intravenous Lignocaine-Fentanyl Versus Epidural Ropivacaine-Fentanyl for Postoperative Analgesia After Major Abdominal Oncosurgery: A Pilot Prospective Randomised Study. (Pubmed Central) - May 20, 2021
The incidence of intraoperative hypotension requiring bolus mephenteramine injection was significantly higher in the EPI group than the IV group (36% vs. 17%; p<0.001). Intravenous lignocaine-fentanyl and epidural ropivacaine-fentanyl have comparable postoperative analgesic efficacies after major open abdominal oncosurgery.
- || mefenamic acid / Generic mfg.
Clinical, Journal: Assessment of C-reactive Protein Level and Efficacy of Diclofenac Sodium and Mefenamic Acid in Relieving Pain in Mandibular Impacted Third Molar Surgery. (Pubmed Central) - May 20, 2021
Diclofenac sodium can be used to relieve pain. The CRP level evaluation can be helpful to assess inflammation following surgery.
- | lignocaine / Generic mfg.
Journal: Oxygen delivery by mask improves the PaO of pregnant ewes during short term anaesthesia for caesarean delivery of preterm lambs. (Pubmed Central) - May 20, 2021
Twenty-six pregnant Merino cross ewes at 121-123 days of gestation were anaesthetised with intravenous midazolam and ketamine for subarachnoid administration of 60 mg of lignocaine and caesarean delivery of the preterm lamb...The PaO of ewes receiving oxygen by face mask was higher than previously reported [92.6 ± 44.0 mmHg compared to 45.2 ± 11.8 mmHg (Musk and Kemp, 2018) (p = 0.0007)]. Oxygen delivery by mask improved the PaO of pregnant ewes during short term anaesthesia.
- || lignocaine / Generic mfg.
Clinical, Journal: Comparative clinical trial of intracameral ropivacaine vs. lignocaine in subjects undergoing phacoemulsification under augmented topical anesthesia. (Pubmed Central) - May 15, 2021
Intracameral Ropivacaine and Lignocaine, both are equally effective in providing analgesia during phacoemulsification. However, intracameral Ropivacaine is superior to Lignocaine with regards to corneal endothelial cell safety, and augmenting mydriasis.
- || lignocaine / Generic mfg.
Retrospective data, Review, Journal: Perioperative intravenous lignocaine infusion for postoperative pain control in patients undergoing surgery of the spine: protocol for a systematic review and meta-analysis. (Pubmed Central) - May 15, 2021
The results will be disseminated through a peer-reviewed publication. CRD420201963314.
- || lignocaine / Generic mfg.
Clinical, Journal, Endobronchial ultrasound: The cricothyroid versus Spray-As-You-Go method for topical anesthesia during Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA): The CRISPEN randomized clinical trial. (Pubmed Central) - May 5, 2021
P=N/A
Cricothyroid lignocaine administration is associated with less cough and superior operator-rated procedure satisfaction during EBUS-TBNA, at a lower cumulative lignocaine dose administered. www.clinicaltrials.gov NCT02981264.
- || lignocaine / Generic mfg.
Clinical, Journal: Comparative Analysis of the Anesthetic Efficacy of 0.5% Ropivacaine Versus 2% Lignocaine Hydrochloride with Adrenaline (1:80,000) for Inferior Alveolar Nerve Block in Surgical Removal of Impacted Mandibular Third Molars. (Pubmed Central) - May 1, 2021
0.5% Ropivacaine had higher depth of anesthesia, longer duration of action and postoperative analgesic effect than 2% Lignocaine hydrochloride with 1:80,000 adrenaline with no adverse effects. 0.5% ropivacaine is safe, efficacious, clinically acceptable and equally potent local anesthetic agent when compared to 2% lignocaine with 1:80,000 adrenaline in oral and maxillofacial surgery for longer duration of surgeries.
- || lignocaine / Generic mfg.
Review, Journal: Tumescent Anesthesia for Dermatosurgical Procedures Other Than Liposuction. (Pubmed Central) - Apr 30, 2021
Nonetheless, one must be vigilant about the signs and symptoms of LAST, as they may not manifest until several hours after the procedure. Lipid emulsion therapy should be readily available and could prove life-saving in such situations.
- || lignocaine / Generic mfg.
Clinical, Journal: Comparison of 0.5% Centbucridine and 2% Lignocaine as Local Anesthetic Agents for Dental Procedures in Children: A Randomised Controlled Trial. (Pubmed Central) - Apr 28, 2021
Lipid emulsion therapy should be readily available and could prove life-saving in such situations. There was no significant difference between 0.5% centbucridine and 2% lignocaine with respect to onset, duration and depth of anesthesia.
- || dexamethasone / Generic mfg., ibuprofen / Generic mfg.
Clinical, Journal: EVALUATING COMBINED EFFECT OF ORAL PREMEDICATION WITH IBUPROFEN AND DEXAMETHASONE ON SUCCESS OF INFERIOR ALVEOLAR NERVE BLOCK IN MANDIBULAR MOLARS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS - A PROSPECTIVE, DOUBLE BLIND, RANDOMIZED CLINICAL TRIAL. (Pubmed Central) - Apr 28, 2021
There was no significant difference between 0.5% centbucridine and 2% lignocaine with respect to onset, duration and depth of anesthesia. Preoperative administration of a combination of dexamethasone and ibuprofen improved the success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis.
- ||| lignocaine / Generic mfg.
39Y/M, DM, DOE, Enzymes-ECHO-Ions normal. Responded to lignocaine(Dr Nilesh) Why this Idioventricular rhythm? #EPeeps @ecgrhythms @SchakrabartiEP @abhishek_mbbs @syamkumarmd @mahishasur @DCR_Dr @anunay_cardio @SuchitMajumder @drnjy @Hapa_EP @PaymardM @narrowQRS (Twitter) - Apr 28, 2021
- | lignocaine / Generic mfg.
New trial: Sedation for Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (clinicaltrials.gov) - Apr 25, 2021
P=N/A, N=90, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
- | lignocaine / Generic mfg.
Journal: Topical lignocaine anaesthesia for oropharyngeal sampling for COVID-19. (Pubmed Central) - Apr 24, 2021
Preoperative administration of a combination of dexamethasone and ibuprofen improved the success rate of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis. Topical lignocaine, while improving the comfort of the procedure of oropharyngeal sampling for patient did not alter the SARS-CoV-2 viral load that was detected in nasal and oropharyngeal samples taken together.
- | NN1213 / Novo Nordisk
Trial primary completion date, Surgery: Randomized Controlled Trial to Assess Blockade of Voltage Gated Sodium Channels During Surgery in Operable Breast Cancer (clinicaltrials.gov) - Apr 22, 2021
P3, N=1600, Active, not recruiting, Sponsor: Tata Memorial Hospital
Topical lignocaine, while improving the comfort of the procedure of oropharyngeal sampling for patient did not alter the SARS-CoV-2 viral load that was detected in nasal and oropharyngeal samples taken together. Trial primary completion date: Dec 2020 --> Dec 2021
- || lidocaine topical / Generic mfg.
Clinical, Journal: Efficacy of lidocaine 7%, tetracaine 7% self-occlusive cream in reducing MAL-cPDT-associated pain in subjects with actinic keratosis: A randomized, single-blind, vehicle-controlled trial (The "3P-Trial"). (Pubmed Central) - Apr 15, 2021
Trial primary completion date: Dec 2020 --> Dec 2021 The 3P-trial has demonstrated that the preventive application of the self-occlusive lidocaine 7%-tetracaine 7% cream is very effective in reducing the procedure-associated pain during MAL-cPDT for the treatment of AK lesions.
- | lignocaine / Generic mfg.
New trial: Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache (clinicaltrials.gov) - Apr 13, 2021
P=N/A, N=42, Recruiting, Sponsor: Zagazig University
- || pethidine / Samaritan
Clinical, Journal, Head-to-Head: A randomized double-blinded non-inferiority trial comparing fentanyl and midazolam with pethidine and diazepam for pain relief during oocyte retrieval. (Pubmed Central) - Apr 13, 2021
The 3P-trial has demonstrated that the preventive application of the self-occlusive lidocaine 7%-tetracaine 7% cream is very effective in reducing the procedure-associated pain during MAL-cPDT for the treatment of AK lesions. The fentanyl and midazolam group had significantly lower vaginal and abdominal pain levels during oocyte retrieval than the pethidine and diazepam group.
- | doxycycline / Generic mfg., azithromycin / Generic mfg., lignocaine / Generic mfg.
New trial: Understanding drug concentrations in the body on the optimisation of sexually transmitted infections (STIs) treatments. (EUDRACT) - Apr 5, 2021
P, N=240, Not yet recruiting, Sponsor: University of Melbourne
- | lignocaine / Generic mfg.
New trial: Safety and Efficacy of a single or multiple intra-articular injections of hyaluronic acid in osteoarthritis. (EUDRACT) - Apr 5, 2021
P, N=90, Completed, Sponsor: Joint Health Institute
- | lignocaine / Generic mfg.
New trial: Paravertebral vs. Erector Spinae Blocks for lung function in those with rib fractures (EUDRACT) - Apr 5, 2021
P, N=40, Not yet recruiting, Sponsor: Middlemore Hospital
- | lignocaine / Generic mfg.
New trial, Biopsy: Transperineal prostate biopsy under local anaesthetic compared to general anaesthetic for men with suspected prostate cancer (EUDRACT) - Apr 5, 2021
P, N=620, Not yet recruiting, Sponsor: Monash Health Department of Urology
- | lignocaine / Generic mfg.
New trial: Effectiveness of Hematoma block in acute pain management and closed reduction of fractures in children presenting to DHQ Kohat: An exploratory RCT (EUDRACT) - Apr 5, 2021
P, N=150, Recruiting, Sponsor: Khalid Rehman
- || epinephrine / Generic mfg., lignocaine / Generic mfg.
Clinical, Journal: Comparison of the pharmacological properties of 0.375% bupivacaine with epinephrine, 0.5% ropivacaine and a mixture of bupivacaine with epinephrine and lignocaine - a randomized prospective study. (Pubmed Central) - Mar 24, 2021
The solution of 0.375% bupivacaine with epinephrine and 0.5% ropivacaine used for axillary brachial plexus anesthesia provide the same level of the block. Addition of short acting local anesthetic - lignocaine to long acting bupivacaine decreases the time to onset of motor blockade, but also shortens the duration of the sensory and motor blockade in the post-operative period, compared to long acting local anesthetics of higher potency: bupivacaine with epinephrine or ropivacaine.
- | lignocaine / Generic mfg.
Journal: Comparison of two topical treatments on wound healing 7 days after disbudding of calves using thermocautery. (Pubmed Central) - Mar 23, 2021
Aims To compare wound healing 7 days after cautery disbudding of dairy calves treated immediately after disbudding with a traditional antimicrobial spray (OXY) or with a topical anaesthetic gel containing cetrimide, adrenaline and two local anaesthetics, lignocaine and bupivacaine (TA)...No sign of infection was seen in any calves.Conclusion and clinical relevance The greater prevalence of granulation tissue and reduction in crusting in disbudding wounds treated with topical anaesthetic gel compared to those treated with the antimicrobial spray suggests that use of the topical anaesthetic gel may speed wound healing compared to using antimicrobial spray. This should be further tested in a larger study undertaken over a longer period.
- | lignocaine / Generic mfg.
New trial: Airway Nerve Block Versus Nebulization by Lignocaine During Diagnostic Flexible Bronchoscopy Under Moderate Sedation. (clinicaltrials.gov) - Mar 19, 2021
P=N/A, N=120, Not yet recruiting, Sponsor: Ain Shams University
- || lignocaine / Generic mfg.
Thx! no worries.I understand.Hopefully the Lignocaine will help and I get to watch the neuro info because I have CRPS too. I'm wondering if the Lignocaine works whether it might be a diagnostic for CRPS spreading to my head via the Vagus nerve? Hmm... 11 days 8-10+ and counting (Twitter) - Mar 18, 2021
- |||| lignocaine / Generic mfg.
Clinical: Yaya! Have shared this everywhere. Including all the Drs and neurologists that I run into especially while I'm in hospital for the darn migraine that won't go away. Lignocaine infusion atm... hmm... (Twitter) - Mar 18, 2021
- || lignocaine / Generic mfg.
Clinical, Journal: Efficacy of 2% Lignocaine and 4% Articaine in Oral Surgical Procedure: A Comparative Study. (Pubmed Central) - Mar 16, 2021
This should be further tested in a larger study undertaken over a longer period. Articaine is more effective compared to lignocaine, hence it can be recommended alternatively for tooth extraction and other oral surgical procedures.
- || lignocaine/adrenaline / Generic mfg., lignocaine / Generic mfg.
Clinical, Journal: Comparison of anaesthetic efficacy of ropivacaine (0.75% & 0.5%) with 2% lignocaine with adrenaline (1:200000) in surgical extraction of bilateral mandibular 3 molars using IANB:a prospective, randomized, single blind study. (Pubmed Central) - Mar 16, 2021
Else mean heart rate lower in other time interval. Ropivacaine (0.75%,0.5%) was more efficacious than 2% lignocaine with adrenaline (1:200000) it terms of all measured parameters in study.
- | dexamethasone / Generic mfg., lignocaine / Generic mfg.
New P4 trial: Effectiveness of Intratympanic Dexamethasone With Ligmocaine for Alleviation of Tinnitus (clinicaltrials.gov) - Mar 15, 2021
P4, N=264, Active, not recruiting, Sponsor: Combined Military Hospital, Pakistan
- | lignocaine / Generic mfg.
New trial: Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients (clinicaltrials.gov) - Mar 10, 2021
P=N/A, N=40, Not yet recruiting, Sponsor: Ain Shams University
- || lignocaine / Generic mfg.
Clinical, Journal: Efficacy of precisely injected single local bolus of lignocaine for alleviation of behavioural responses to pain during tail docking and castration of lambs with rubber rings. (Pubmed Central) - Mar 10, 2021
Ring and NNLA did not differ at any time point between 60 and 180 min. Delivery of lignocaine with the Numnuts® instrument improved welfare outcome of lambs during the acute pain response caused by castration and tail docking with rubber rings.
- | midazolam hydrochloride / Generic mfg.
Journal: Role of medical thoracoscopy in the treatment of complicated parapneumonic effusions. (Pubmed Central) - Mar 10, 2021
There were no major procedure-related complications that required intervention. Early adhesiolysis and drainage of fluid using medical thoracoscopy should be considered in patients with multiloculated complicated PPE after careful radiological (ultrasonography and CT) stratification, as a more cost-effective and safe method of management.
- | dexamethasone / Generic mfg., dexmedetomidine / Generic mfg.
New trial, Surgery: Comparison Of Dexmedetomidine And Dexamethasone As An Adjuvant To Bupivacaine In Brachial Plexus Block (clinicaltrials.gov) - Mar 9, 2021
P=N/A, N=60, Recruiting, Sponsor: Tribhuvan University Teaching Hospital, Institute Of Medicine.
- || piroxicam / Generic mfg.
Clinical, Journal: Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial. (Pubmed Central) - Mar 9, 2021
The piroxicam group presented a significantly lower (p < 0.05) mean pain score than the saline group during AOP. Buccal infiltration with piroxicam enhanced the efficacy of anesthesia with IANB and buccal infiltration with lignocaine in patients with irreversible pulpitis.
- | lignocaine / Generic mfg.
Trial completion, Trial completion date: DiaVACCS: Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women. (clinicaltrials.gov) - Mar 8, 2021
P=N/A, N=1107, Completed, Sponsor: University of Pretoria
Buccal infiltration with piroxicam enhanced the efficacy of anesthesia with IANB and buccal infiltration with lignocaine in patients with irreversible pulpitis. Recruiting --> Completed | Trial completion date: Dec 2021 --> Dec 2020
- | meloxicam / Generic mfg., lignocaine / Generic mfg.
Journal: Evaluation of Electroencephalography, Behaviour and Eye Temperature in Response to Surgical Castration in Sheep. (Pubmed Central) - Mar 7, 2021
CML and C groups had similar results, indicating minimal effect of analgesic intervention. Lambs in SC group showed significant EEG changes, suggesting that stress from handling also impacted EEG results.
- || tranexamic acid / Generic mfg.
Clinical, Journal: Efficacy of Topical Tranexamic Acid (Cyclokapron) in "Wet" Field Infiltration with Dilute Local Anaesthetic Solutions in Plastic Surgery. (Pubmed Central) - Feb 26, 2021
This is the first study examining addition of tranexamic acid to a tumescent infiltration solution-to produce a predictable local concentration of tranexamic acid-in order to maximize surgical site effect and minimize systemic effect. The authors recommend incorporation of tranexamic acid as a routine component along with adrenaline and local anaesthetics in tumescent field infiltration solution 10-15 min before commencement of the cosmetic surgery.
- | lignocaine / Generic mfg.
Trial completion, Enrollment change: A Randomized Trial of 4% Nebulized Lignocaine vs. 10% Lignocaine Spray in Patients Undergoing Flexible Bronchoscopy (clinicaltrials.gov) - Feb 23, 2021
P2/3, N=1050, Completed, Sponsor: Postgraduate Institute of Medical Education and Research
The authors recommend incorporation of tranexamic acid as a routine component along with adrenaline and local anaesthetics in tumescent field infiltration solution 10-15 min before commencement of the cosmetic surgery. Recruiting --> Completed | N=750 --> 1050
- | lignocaine / Generic mfg.
New trial: Comparison Between Systemic Steroids, Topical Steroids, or Calcineurin Inhibitors With Mini Punch Grafting in Treatment of Stable Non-segmental Vitiligo (clinicaltrials.gov) - Feb 20, 2021
P=N/A, N=60, Recruiting, Sponsor: Alexandria University
- | lignocaine / Generic mfg.
Journal: Pain Perception During the Phases of Manual Reduction of Distal End Radius Fracture With a Periosteal Block. (Pubmed Central) - Feb 20, 2021
The reduction was performed using a periosteal block of 10 ml of 2% lignocaine injection...Conclusions The periosteal nerve block is an effective procedure providing satisfactory analgesia during the reduction of distal radial and ulnar fractures. It has no side effects and is free from complications associated with conventional sedation.
- || lignocaine / Generic mfg.
Clinical, Journal: DentalVibe reduces pain during the administration of local anesthetic injection in comparison to 2% lignocaine gel: results from a clinical study. (Pubmed Central) - Feb 16, 2021
The primary outcome was pain, which was recorded immediately after the administration of anesthetic injection using the Visual Analogue Scale [VAS 0 - 10]. The VAS pain scores ranged from 4 to 10 for site A and 0 to 6 for site B. Comparison between the two sites showed a statistically significant difference [Mann-Whitney U test value = 51.50, P < 0.001] favoring site B. This study showed that DentalVibe reduces pain during injection of local anesthesia compared to topical anesthetic gel.
- | lignocaine / Generic mfg.
Enrollment open, Trial initiation date: Evaluation of Clinical Efficacy of Different Injection Therapies for Treating Humeral Epicondylopathy (clinicaltrials.gov) - Feb 10, 2021
P4, N=200, Recruiting, Sponsor: Wroclaw Medical University
The VAS pain scores ranged from 4 to 10 for site A and 0 to 6 for site B. Comparison between the two sites showed a statistically significant difference [Mann-Whitney U test value = 51.50, P < 0.001] favoring site B. This study showed that DentalVibe reduces pain during injection of local anesthesia compared to topical anesthetic gel. Not yet recruiting --> Recruiting | Initiation date: Nov 2020 --> Feb 2021
- | diltiazem / Generic mfg.
Journal: Comparative Study to Assess the Effectiveness of Topical Nifedipine and Diltiazem in the Treatment of Chronic Anal Fissure. (Pubmed Central) - Feb 4, 2021
There was no significant difference between the two CCBs. Adding topical Nifedipine or Diltiazem in the treatment of anal fissure is far superior to treatment with only topical Lignocaine.
- | lignocaine / Generic mfg.
New trial: Evaluation of Efficacy of Platelet Rich Plasma as Anew Modality for Treatment of Atrophic Rhinitis (clinicaltrials.gov) - Jan 21, 2021
P=N/A, N=40, Not yet recruiting, Sponsor: Sohag University