lignocaine / Generic mfg. 
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 7 Diseases   124 Trials   124 Trials   723 News 


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  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Rehabilitation Following Multiple Limb Amputation: A Case Report. (Pubmed Central) -  Mar 10, 2025   
    The patient was managed with a multidisciplinary strategy, incorporating stump-strengthening exercises, scar mobilization techniques, and transcutaneous electrical nerve stimulation (TENS) therapy for neuroma management, supplemented by the administration of 2% lignocaine...Functional progress was assessed using the Nottingham Extended Activities of Daily Living (ADL) Index, which showed a significant improvement from a score of 0 to 27 after two weeks of rehabilitation. This case underscores the importance of individualized, multidisciplinary care in achieving optimal functional outcomes and quality of life for patients with multiple limb amputations.
  • ||||||||||  lignocaine / Generic mfg.
    New trial:  ITPB 1 Vs 3 in VATS (clinicaltrials.gov) -  Feb 21, 2025   
    P=N/A,  N=80, Not yet recruiting, 
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Extensive supraglottic mass-An anesthetist's nightmare. (Pubmed Central) -  Feb 17, 2025   
    Successful intubation was followed by an uneventful surgical procedure and a smooth recovery. This case highlights the efficacy and safety of awake fiber-optic intubation in managing difficult airways in patients with supraglottic tumors, minimizing complications and enhancing patient outcomes.
  • ||||||||||  tramadol hydrochloride / Generic mfg., lignocaine / Generic mfg.
    Observational data, Journal:  Patient tolerance during rigid cystoscopy: An observational study comparing lignocaine hydrochloride gel and tramadol with lignocaine. (Pubmed Central) -  Feb 10, 2025   
    There was a significant difference in terms of VAS score (p?=?<?0.001), with the median Score being lower in the Lignocaine gel?+?tramadol group and higher when lignocaine gel?+?tramadol used among patients with Diabetes mellitus. The instillation of lignocaine gel in conjunction with tramadol in urethra could decrease pain perception during the procedure except in people with diabetes mellitus, hence make men undergoing rigid cystoscopy more comfortable during the procedure there by increase diagnostic and therapeutic outcome.
  • ||||||||||  lignocaine / Generic mfg.
    Retrospective data, Journal:  Efficacy and safety of intravesical alkalinized lignocaine for cystoscopy: a retrospective analysis. (Pubmed Central) -  Feb 7, 2025   
    The instillation of lignocaine gel in conjunction with tramadol in urethra could decrease pain perception during the procedure except in people with diabetes mellitus, hence make men undergoing rigid cystoscopy more comfortable during the procedure there by increase diagnostic and therapeutic outcome. Using intravesical AL solution significantly reduces pain and improves patient tolerance and satisfaction during cystoscopy; also, it is safe and well-tolerated.
  • ||||||||||  lignocaine / Generic mfg., dexmedetomidine / Generic mfg.
    Clinical, Journal:  Effect of Anaesthesia Technique on anti-tumor Immunity through TGF-? levels in Adult Patients Undergoing Surgery for Oral Cancer. (Pubmed Central) -  Dec 29, 2024   
    We did not find any statistically significant difference in the Post-operative levels of TGF-?, neutrophil-lymphocyte ratio (NLR), Monocyte Lymphocyte Ratio (MLR), platelet lymphocyte ratio (PLR), IL-6, IL-10, and T-helper cell profile( IFN-?, IL-17A, and IL-4 as surrogate markers) among the three study groups. However, it was noted that the overall Opioid consumption was markedly reduced in Group C without any major adverse effects being noted.
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Interventional Physiatry in the Complex Regional Pain Syndrome of the Upper Limb Following Herpes Zoster. (Pubmed Central) -  Dec 23, 2024   
    The patient received an ulnar and median nerve block using a mixture of 10 mg methylprednisolone and 2% lignocaine (30 mg)...Previous studies have shown "CRPS-like" symptoms following herpes zoster, and this case highlights the value of a multimodal treatment approach that combines interventional techniques with physical therapy. This case illustrates the rarity of post-herpetic CRPS and the effectiveness of peripheral nerve blocks, medication, and exercise in achieving significant pain relief and functional recovery.
  • ||||||||||  lignocaine / Generic mfg.
    Trial completion date, Trial primary completion date:  Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers (clinicaltrials.gov) -  Dec 18, 2024   
    P4,  N=155, Active, not recruiting, 
    This case illustrates the rarity of post-herpetic CRPS and the effectiveness of peripheral nerve blocks, medication, and exercise in achieving significant pain relief and functional recovery. Trial completion date: Jun 2025 --> Jun 2027 | Trial primary completion date: Jan 2025 --> Jan 2027
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Hyperocclusive technique for topical anesthesia for injecting botulinum toxin in palmar hyperhidrosis. (Pubmed Central) -  Dec 9, 2024   
    Injecting botulinum toxin under simple topical anesthesia using a eutectic mixture of lignocaine and prilocaine is a painful procedure. A simple hyper-occlusive modification in the existing technique of topical anesthesia of palms facilitates painless injections leading to greater patient satisfaction and compliance.
  • ||||||||||  lignocaine / Generic mfg.
    Assessing Lignocaine in Distension Medium for Pain in Office Hysteroscopy: RCT (Room: 272) -  Nov 17, 2024 - Abstract #AAGL2024AAGL_385;    
    Incorporating a local anaesthetic into the distension medium for hysteroscopy not only significantly reduces the pain levels during and after the procedure but also shortens procedural duration and demonstrates no adverse effects. Morever, it enhances patient satisfaction.
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Hyperkalemia During Prolonged Anesthesia in a Greyhound. (Pubmed Central) -  Nov 17, 2024   
    The dog was discharged from hospital in a stable condition. Unanticipated hyperkalemia during anesthesia was treated in an otherwise healthy greyhound undergoing a dental procedure.
  • ||||||||||  Maxidex (dexamethasone eye drops, suspension) / Novartis, Ozurdex (dexamethasone intravitreal implant) / AbbVie
    Trial completion date, Trial primary completion date:  Particulate Vs. Non-Particulate Steroid for Sacroiliac Joint Injection (clinicaltrials.gov) -  Oct 21, 2024   
    P4,  N=230, Recruiting, 
    Not yet recruiting --> Recruiting Trial completion date: May 2025 --> May 2027 | Trial primary completion date: Jan 2025 --> Jan 2027
  • ||||||||||  lignocaine / Generic mfg.
    Journal:  Effective Use of Intravenous Lignocaine for Radiotherapy-Induced Brachial Plexopathy. (Pubmed Central) -  Oct 7, 2024   
    The patient exhibited a remarkable response to intravenous (IV) lidocaine infusion, with near-complete resolution of her symptoms. This case highlights the potential of IV lidocaine infusion as a valuable component of a multimodal strategy for managing RIBP.
  • ||||||||||  lignocaine / Generic mfg.
    Retrospective data, Review, Journal:  Perioperative intravenous lignocaine for pediatric postoperative pain-A systematic review and meta-analysis. (Pubmed Central) -  Oct 4, 2024   
    There is low quality evidence to suggest that perioperative intravenous lignocaine bolus followed by an infusion significantly reduced the opioid consumption on the first postoperative day in pediatric surgical patients. The effects of perioperative lignocaine on postoperative pain scores and the need for rescue analgesia are uncertain.