- |||||||||| morphine sulphate / Generic mfg., methadone / Generic mfg.
Review, Journal: Opioid agonist treatment for people who are dependent on pharmaceutical opioids. (Pubmed Central) - Sep 14, 2022
Maintenance treatment with buprenorphine appears more effective than non-opioid treatments. Due to the overall very low- to moderate-certainty evidence and small sample sizes, there is the possibility that the further research may change these findings.
- |||||||||| morphine sulphate / Generic mfg.
Journal: Application of risk assessment tools to predict opioid usage after shoulder surgery. (Pubmed Central) - Sep 13, 2022
The SOAPP-R performed slightly better (area under curve = 0.70) and was the only assessment with significantly different mean scores between patients with postoperative opioid dependence and those without (33.4 and 24.5, respectively, P = .049) and a moderate correlation to postoperative total morphine equivalents (R = 0.46, P = .007)...While the ORT may be helpful in other fields, it does not seem to be a strong predictor of postoperative opioid use or dependence in patients undergoing various types of shoulder surgery. Future studies are needed to explore the utility of the SOAPP-R in a larger sample and identify tools applicable to the orthopedic population to assist surgeons in screening at-risk patients.
- |||||||||| morphine sulphate / Generic mfg.
Retrospective data, Journal: A retrospective study comparing postoperative opioid prescribing practices in an academic medical centre. (Pubmed Central) - Sep 13, 2022
Patients who underwent open abdominal surgeries were prescribed significantly higher daily doses of morphine milligram equivalents (MME) (45 mg; interquartile range, 30-60), than patients who underwent either a caesarean delivery (20 mg, 20-20) or a hysterectomy (30 mg, 22-30)...Efforts to optimize safer prescribing practices should address the creation and/or updating of preprinted order sets to reflect current best practice guidelines. This initiative could be overseen by hospital pharmacy and therapeutics committees.
- |||||||||| morphine sulphate / Generic mfg.
Intrathecal morphine, a way to achieve opioid-free pain management within an ERAS (ePoster kiosks (Exhibition area)) - Sep 12, 2022 - Abstract #ESGO2022ESGO_1112;
Our results show that intrathecal morphine is an effective method of postoperative analgesia in patients undergoing radical oncogynecologic surgery. We managed to minimize the use of systemic opioids with a very low frequency of side effects.
- |||||||||| Palexia RP (tapentadol extended release) / Assertio, J&J, Grunenthal, Collegium Pharma, Nucynta (tapentadol) / Collegium Pharma, Grunenthal
Clinical, Journal: Incidence of Delirium With Different Oral Opioids in Previously Opioid-Naive Patients. (Pubmed Central) - Sep 12, 2022
We managed to minimize the use of systemic opioids with a very low frequency of side effects. The incidence of delirium in previously opioid-naive patients did not differ significantly among morphine sulfate, oxycodone hydrochloride, and tapentadol hydrochloride extended-release tablets, suggesting similar risk of delirium in opioid-naive patients among these oral opioids.
- |||||||||| Invanz (ertapenem) / Merck (MSD)
VENOUS AIR EMBOLISM: A CASE REPORT (Convention Center Exhibit Hall: Rapid Area 2B) - Sep 11, 2022 - Abstract #CHEST2022CHEST_4182;
The patient improved with the above-mentioned therapy and was discharged to complete 14 days of IV ertapenem... A high degree of clinical suspicion is required for timely diagnosis and management of air embolism to decrease morbidity and mortality.
- |||||||||| piperacillin sodium/tazobactam sodium / Generic mfg., vancomycin / Generic mfg., morphine sulphate / Generic mfg.
RARE FOURNIER GANGRENE WITH RESULTING SEPTIC SHOCK DUE TO CHRONICALLY UNTREATED INGUINAL HERNIA (Convention Center Exhibit Hall: Rapid Area 1D) - Sep 11, 2022 - Abstract #CHEST2022CHEST_4127;
Prompt fluid management and source control can help halt the illness and well as spread to neighboring structures. Stressing the importance of HAART therapy in an outpatient setting can decrease risk of weakened immune system, making patients less prone to FG.
- |||||||||| morphine sulphate / Generic mfg., hydromorphone hydrochloride / Generic mfg.
ATYPICAL PRESENTATION OF CARDIAC TAMPONADE SECONDARY TO MALIGNANT THYMIC NEUROENDOCRINE TUMOR MASKED BY OPIOID OVERDOSE (Convention Center Exhibit Hall: Rapid Area 1A) - Sep 11, 2022 - Abstract #CHEST2022CHEST_3731;
Prior to arrival, patient was found on her bed with limited responsiveness; due to the extensive nature of her tumor burden, patient was using a morphine pump as well as oral hydromorphone for pain control. Here, we present a case of cardiac tamponade that was masked by our patient's initial presentation of opioid overdose and ultimately treated with timely pericardiocentesis.
- |||||||||| morphine sulphate / Generic mfg.
Journal: Group-based trajectory analysis of acute pain after spine surgery and risk factors for rebound pain. (Pubmed Central) - Sep 11, 2022
The relationships between the postoperative pain trajectories and the amount of morphine consumption or length of hospital stay (LOS) after surgery were also evaluated...The group-based trajectory analysis of postoperative pain provides insight into the patterns of pain resolution and helps to identify unusual courses. More aggressive pain management should be considered in patients with a higher risk for rebound pain after the end of IVPCA for spine surgery.
- |||||||||| morphine sulphate / Generic mfg.
Celiac Plexus Radio-Surgery for Pain Management in Advanced Cancer: An International Phase II Trial (Henry B. Gonzalez Convention Center, Hemisfair Ballroom C2/C3) - Sep 11, 2022 - Abstract #ASTRO2022ASTRO_2716;
Celiac plexus SBRT decreases pain, opioid use and pain interference scores with minimal side effects, providing a new possible treatment option for pancreatic cancer pain & other tumors invading the celiac axis. Supported by Gateway for Cancer Research and the Israel Cancer Association.
- |||||||||| morphine sulphate / Generic mfg., ropivacaine / Generic mfg.
Journal: Continuous Bupivacaine Infusion versus Liposomal Bupivacaine in Adductor Canal Block for Total Knee Arthroplasty. (Pubmed Central) - Sep 10, 2022
Morphine equivalent dose (MED), pain scores, and length of stay (LOS) were compared between the two groups by using the analysis of covariance test...OnQ comparatively prolonged infusion of local anesthetic is a potential edge over LB. This advantage may offset the inconvenience of catheter management and infrequent catheter complications.
- |||||||||| morphine sulphate / Generic mfg.
Journal: Opium, street opium and cancer risk. (Pubmed Central) - Sep 10, 2022
Opium is defined as the air-dried latex obtained by incision from the unripe capsules of Papaver somniferum L. Opium is a complex mixture that contains approximately 10% morphine and 2% codeine...To avoid confusion and concern in health professionals and patients using medicinal opium preparations, and in scientists involved in the design and development of new opium derivatives, opium should be classified in Group 3 (not classifiable as to its carcinogenicity to humans). The term 'street opium' could be used to refer to opium that probably contains human carcinogens not present in pure opium, and should remain in Group 1 (carcinogenic to humans).
- |||||||||| morphine sulphate / Generic mfg.
Journal: Evaluating Outcomes of a Pharmacist-Driven Pain Management Consult Service. (Pubmed Central) - Sep 10, 2022
Additionally, there was a statistically significant reduction in the number of morphine milligram equivalents (MMEs) at 48 hours post consult (149.4 vs. 133.8; p < 0.001; Table 4) and 24 hours prior to discharge (136.5 vs. 100.6; p < 0.001; Table 4) when compared to 24 hours prior to consult. This pharmacist-driven pain consult service demonstrated a statistically significant reduction in pain scores while simultaneously reducing MME utilization and the number of opioids ordered, using a multimodal evidence-driven approach to pain management in a community hospital.
- |||||||||| morphine sulphate / Generic mfg.
Journal: Topical Morphine Gel as a Systemic Opioid Sparing Technique. (Pubmed Central) - Sep 10, 2022
In this single-center analysis, patients with painful chronic wounds treated with morphine gel required lower doses of systemic opioids. Topical morphine gel may provide analgesia while sparing systemic opioid use.
- |||||||||| Instanyl (fentanyl) / Takeda
Review, Journal: Analgesia for Retinopathy of Prematurity Screening: A Systematic Review. (Pubmed Central) - Sep 10, 2022
Non-pharmacological measures, such as sweet oral solutions and comfort techniques should also be employed. Further research is required to determine whether the use of nitrous oxide has a role, and to develop a safe and effective analgesic strategy to fully ameliorate the pain of ROP screening.
- |||||||||| fentanyl citrate / Generic mfg.
Journal: Investigation of Fentanyl Usage in the Seattle Area. (Pubmed Central) - Sep 10, 2022
Further research is required to determine whether the use of nitrous oxide has a role, and to develop a safe and effective analgesic strategy to fully ameliorate the pain of ROP screening. Clinical data from community toxicology testing performed at academic medical centers can reflect trends in society at large, and as such, there may be a compelling reason to publish and use these data to inform public health approaches.
- |||||||||| morphine sulphate / Generic mfg.
Reimbursement, Journal, Medicaid: Opioid prescribing restrictions and opioid use among the Louisiana Medicaid population. (Pubmed Central) - Sep 10, 2022
Therefore, we speculated that miRNA-200a is a positive regulator, which may inhibit the growth of CCSMCs by activating the Rho/ROCK pathway in vitro. These findings suggest that efforts to limit opioid exposure through the implementation of prescription quantity limits and MME restrictions in Louisiana's Medicaid program were successful and are likely to be associated with a reduction in future opioid dependency among the state's Medicaid population.
- |||||||||| ketamine / Generic mfg.
Journal: Novel uses of ketamine in the emergency department. (Pubmed Central) - Sep 10, 2022
Finally, there is growing evidence that suggests ketamine may have a potential utility in the management of patients with self-harm ideation or acute depressive episodes. Intravenous infusion of ketamine (0.5 mg/kg over 40 mins) has been shown to produce an antidepressant effect and decrease in suicidal ideation within 4 hours with effects lasting up to one week.
- |||||||||| morphine sulphate / Generic mfg., paracetamol / Generic mfg.
Retrospective data, Journal: Trends in opioid analgesic utilisation among people with a history of opioid dependence. (Pubmed Central) - Sep 10, 2022
People with opioid dependence had high rates of recent psychotropic medicine utilisation and current OAT enrolment at the time of opioid analgesic initiation. OAT was associated with a significant reduction in opioid analgesic dispensing.
- |||||||||| fentanyl citrate / Generic mfg.
Journal: How much illegally manufactured fentanyl could the U.S. be consuming? (Pubmed Central) - Sep 10, 2022
For comparison, the most recent best estimates of the amount of cocaine and heroin consumed in the U.S. are 145 and 47 pure metric tons, respectively. The article also raises questions about the limitations of using traditional equianalgesic morphine equivalent dose conversions to estimate the total market consumption of IMF.
- |||||||||| Journal: Postoperative analgesia for complex spinal surgery. (Pubmed Central) - Sep 10, 2022
Pain management after complex spinal surgery remains challenging. Therefore, further studies are still required to determine the optimal multimodal analgesic regimen for these patients.
- |||||||||| morphine sulphate / Generic mfg.
Journal: Pharmacist Opioid Dispensing Confidence in an Evolving Practice Landscape. (Pubmed Central) - Sep 10, 2022
Comfort with dispensing opioids decreased over a 12-month period among pharmacists surveyed. Improved communication between prescriber and pharmacist, as well as enhanced access to patient health information, is critical to reduce barriers to care for patients.
- |||||||||| morphine sulphate / Generic mfg., paracetamol / Generic mfg.
Retrospective data, Journal: Acupuncture for pain control after degenerative lumbar spine surgery. (Pubmed Central) - Sep 10, 2022
In summary, our results support the indication of CBD as an adjuvant to opioid therapy for the attenuation of NP and opioid-induced analgesic tolerance. Acupuncture may be as effective as traditional analgesia and PCA for adjuvant pain control after surgery for degenerative lumbar spine disease.
- |||||||||| dexmedetomidine / Generic mfg.
Retrospective data, Journal: The Preventive Effect of Dexmedetomidine Against Delirium in Patients with Aortic Dissection: A Retrospective Cohort Study. (Pubmed Central) - Sep 10, 2022
The use of DEX reduced the incidence of delirium in Stanford type B AD patients during ICU stay, therefore reducing the risk of medical accidents and risk of rupture of the aortic dissecting aneurysm. The preventive effect of DEX against delirium in Stanford type A AD patients was not obvious, and whether increasing the dosage of DEX could enhance the therapeutic efficacy in this group of patients needs to be further observed in future studies.
- |||||||||| morphine sulphate / Generic mfg.
Journal: Reduction in opioid prescribing and administration in hospitalized acute care medical patients. (Pubmed Central) - Sep 10, 2022
Results showed 9.4 percent decrease in opioid morphine equivalent units, 3.4 percent reduction in opioid administrations, and 5.1 percent increase in alternatives to opioid administrations per patient day. Specialty-specific opioid prescribing guidance can help hospitalists change opioid prescribing behavior and should be considered in other specialties.
- |||||||||| fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg.
Retrospective data, Journal: Patient-controlled analgesia and oral mucositis pain in hematological malignancies. (Pubmed Central) - Sep 10, 2022
Two-thirds of included patients had ceased PCA therapy by day 6, by which time there was a meaningful 35.4 percent reduction in pain scores, with very few side effects reported. Interagent comparison demonstrated no significant differences in mean daily pain scores; however, a larger sample size would facilitate an investigation of clinically significant nuances in treatment differences, if they exist.
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