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7 Diseases |  |
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379 Trials |  |
12426 News |  |
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- | morphine sulphate / Generic mfg.
Journal: Sufentanil Sublingual Tablet System vs. Intravenous Patient-Controlled Analgesia with Morphine: Postoperative Pain Control and Its Impact in Quality of Recovery. (Pubmed Central) - Nov 29, 2023
The study suggests that both IV morphine and sublingual sufentanil are safe and effective for postoperative pain management.
- | morphine sulphate / Generic mfg.
Journal: Effects of Opioid-Limiting Legislation in the State of Ohio on Opioid Prescriptions After Shoulder Arthroscopy. (Pubmed Central) - Nov 29, 2023
The study suggests that both IV morphine and sublingual sufentanil are safe and effective for postoperative pain management. Recent studies have shown that legislation regulating opioid prescriptions in the United States has been successful in reducing the morphine milligram equivalent (MME) prescribed after certain orthopaedic procedures...Opioid prescription-limiting legislation in Ohio significantly reduced the cumulative MME prescribed in the first 30 days postoperatively for both opioid-na
- | morphine sulphate / Generic mfg., ketamine / Generic mfg.
Clinical protocol, Journal: Randomised controlled trial of analgesia for the management of acute severe pain from traumatic injury: study protocol for the paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN). (Pubmed Central) - Nov 29, 2023
The PACKMAN study is the first UK clinical trial addressing the clinical and cost-effectiveness of ketamine and morphine in treating acute severe pain from traumatic injury treated by NHS paramedics. The findings will inform future clinical practice and provide insights into the effectiveness of ketamine as a prehospital analgesia.
- | Journal: Trends in sedation-analgesia practices in pediatric liver transplant patients admitted postoperatively to the pediatric intensive care unit: An analysis of data from the pediatric health information system (PHIS) database. (Pubmed Central) - Nov 29, 2023
The overall utilization of dexmedetomidine and ketamine was more frequent, whereas the administration of benzodiazepines was less during the study period. Pediatric intensivists have a distinctive opportunity to collaborate with the liver transplant team to develop comprehensive guidelines for sedation and analgesia, aimed at enhancing the quality of care provided to these patients.
- | Nucynta (tapentadol) / Collegium Pharma, Grunenthal
Journal, Surgery: Opioid prescribing, pain, and hospital stay of general surgery patients with oxycodone allergies in South Australia. (Pubmed Central) - Nov 29, 2023
General surgery patients with oxycodone allergies and intolerances are at greater risk of worse postoperative pain and longer length of stay, compared to patients without. Many still receive oxycodone, and other opioids that could cause cross-reactivity.
- | morphine sulphate / Generic mfg., hydromorphone hydrochloride / Generic mfg.
Retrospective data, Journal: Comparing Post-operative Opioid Consumption before and after a Patient-Controlled Analgesia Shortage: A Re-evaluation of Safety and Effectiveness. (Pubmed Central) - Nov 29, 2023
Many still receive oxycodone, and other opioids that could cause cross-reactivity. The primary outcome was opioid consumption in average daily oral morphine milliequivalents (MME)...There was no difference in pain AUC/T (0.19?
- | morphine sulphate / Generic mfg.
Trial completion date, Trial primary completion date: MORPHEUS I/IIa: Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa (clinicaltrials.gov) - Nov 29, 2023
P1/2, N=24, Recruiting, Sponsor: University Hospital, Grenoble
The primary outcome was opioid consumption in average daily oral morphine milliequivalents (MME)...There was no difference in pain AUC/T (0.19? Trial completion date: Jul 2024 --> Jan 2027 | Trial primary completion date: Jun 2024 --> Jun 2026
- | Journal: Opioid-related deaths and their counterpart by occurrence-era, age-group and co-implicated drugs: Scotland versus England and Wales. (Pubmed Central) - Nov 28, 2023
Trial completion date: Jul 2024 --> Jan 2027 | Trial primary completion date: Jun 2024 --> Jun 2026 Drug-testing to inform users, shared intelligence between police and public health for earlier detection of changes in supply and monitoring of prescribed daily-dose of methadone are urgent.
- | morphine sulphate / Generic mfg.
Journal: Outcomes of initially nonoperative management of diverticulitis with abscess formation in immunosuppressed patients. DIPLICAB study COLLABORATIVE group. (Pubmed Central) - Nov 28, 2023
IMS presented higher mortality in emergency surgery and similar rate of recurrent diverticulitis than IC. Identifying risk factors to emergency surgery may anticipate emergency surgery.
- | morphine sulphate / Generic mfg.
Retrospective data, Journal: Robotic retroperitoneal lymph node dissection for paratesticular rhabdomyosarcoma in adolescents: a case series. (Pubmed Central) - Nov 28, 2023
Inpatient median total opioid use was 1.8 (0.4-2.7) morphine equivalent/kg...Our series demonstrates the feasibility, safety, and efficacy of the RA approach for RPLND in pediatric patients with paratesticular RMS. This is the most extensive case series currently in the literature and the only one exclusively done for paratesticular RMS.
- | morphine sulphate / Generic mfg.
Journal: Pre-mating administration of theophylline could prevent the transgenerational effects of maternal morphine dependence on offspring anxiety behavior: The role of dopamine receptors. (Pubmed Central) - Nov 28, 2023
It is concluded that theophylline may be therapeutically effective in minimizing the adverse consequences of maternal morphine dependence on offspring behavior by restoring normal dopamine receptor expression levels and lowering anxiety. To completely comprehend the underlying mechanisms of this phenomenon, more research is required.
- | morphine sulphate / Generic mfg.
Observational data, Journal: Mu and Kappa opioid receptor immunolabeling indicates the prognosis of oropharyngeal squamous cell carcinoma: a cross-sectional observational study. (Pubmed Central) - Nov 28, 2023
To completely comprehend the underlying mechanisms of this phenomenon, more research is required. We found increased expression of opioid receptors
- | morphine sulphate / Generic mfg.
Journal, Surgery: Cardiac Enhanced Recovery Program Implementation and Its Effect on Opioid Administration in Adult Cardiac Surgery. (Pubmed Central) - Nov 28, 2023
The transition to ERAS resulted in a 79% reduction in morphine equivalents through postoperative day 1 (359.3 mg pre-ERAS vs 75.4 mg ERAS, P < 0.0001)...The transition to cardiac ERAS resulted in significantly reduced opioid administration and improved patient pain scores while maintaining excellent outcomes. Well-supported, multidisciplinary teams of cardiac surgeons, anesthesiologists, and intensivists can dramatically reduce opioid use without sacrificing pain control or excellent clinical outcomes.
- | morphine sulphate / Generic mfg.
Trial completion: Comparison of Two Pain-treatment Techniques After Cesarean Section (clinicaltrials.gov) - Nov 28, 2023
P4, N=232, Completed, Sponsor: Micha? Borys
Well-supported, multidisciplinary teams of cardiac surgeons, anesthesiologists, and intensivists can dramatically reduce opioid use without sacrificing pain control or excellent clinical outcomes. Unknown status --> Completed
- || dexmedetomidine / Generic mfg.
Retrospective data, Review, Journal: Dexmedetomidine versus Opioids on Labor Analgesia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. (Pubmed Central) - Nov 27, 2023
Neuraxial dexmedetomidine is more favorable than neuraxial opioids for labor analgesia. Extrapolation of the findings to clinical practice should take into considerations the review limitations.
- | morphine sulphate / Generic mfg.
Retrospective data, Journal: A Retrospective Study: Multimodal Analgesia Quality Measure Implementation and Patient Outcome Assessment. (Pubmed Central) - Nov 27, 2023
The treatment group had reduced total intraoperative MMEs and pain scores at PACU arrival. However, there was no statistical significance in PACU discharge pain score, total PACU MMEs, and PONV in both groups.
- | morphine sulphate / Generic mfg.
Journal: Clinical Observation, Management and Function Of low back pain Relief Therapies (COMFORT): A cluster randomised controlled trial protocol. (Pubmed Central) - Nov 27, 2023
The primary outcome will be the cumulative dose of opioid dispensed that was prescribed by study GPs over 1?year from the enrolment visit (in morphine milligram equivalent dose)...The results will be disseminated via publications in journals, media and conference presentations. ACTRN12622001505796.
- | morphine sulphate / Generic mfg.
Journal: Adjunctive tonic motor activation enables opioid reduction for refractory restless legs syndrome: a prospective, open-label, single-arm clinical trial. (Pubmed Central) - Nov 27, 2023
P=N/A
For refractory RLS, TOMAC enabled substantial opioid dose reduction without increased RLS symptoms. These results suggest that TOMAC has the potential to reduce the risk profile associated with opioid therapy for refractory RLS.
- | fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg.
Journal: Energetics of high temperature degradation of fentanyl into primary and secondary products. (Pubmed Central) - Nov 27, 2023
These results suggest that TOMAC has the potential to reduce the risk profile associated with opioid therapy for refractory RLS. Due to its higher potency (50-100
- | morphine sulphate / Generic mfg.
Journal: Early qualitative and quantitative amplitude-integrated electroencephalogram and raw electroencephalogram for predicting long-term neurodevelopmental outcomes in extremely preterm infants in the Netherlands: a 10-year cohort study. (Pubmed Central) - Nov 27, 2023
Due to its higher potency (50-100 These findings highlight the potential benefits of using early postnatal aEEG-EEG features to automatically recognise extremely preterm infants with poor outcomes, facilitating the development of an interpretable prognostic tool that aids in decision making and therapy planning.
- | morphine sulphate / Generic mfg.
Journal: On-Demand Opioid Effect Reversal with an Injectable Light-Triggered Polymer-Naloxone Conjugate. (Pubmed Central) - Nov 27, 2023
Upon irradiation with blue (400 nm) light, the nanoparticles released free naloxone, reversing the effect of morphine in mice. Such triggered events could be performed days and weeks after the initial administration of the nanoparticles and could be performed repeatedly.
- | morphine sulphate / Generic mfg.
Journal: Intercostal nerve cryoablation reduces opioid utilization after thoracotomy in children with cancer. (Pubmed Central) - Nov 27, 2023
INC is a feasible and safe adjunct for children undergoing thoracotomy for cancer. INC is associated with reduced postoperative opioid utilization with respect to both inpatient use and outpatient prescriptions.
- | Journal: An opioid-minimizing multimodal pain regimen reduces opioid exposure and pain in trauma-injured patients at high risk for opioid misuse: Secondary analysis from the mast trial. (Pubmed Central) - Nov 27, 2023
This study is the first to show the moderating influence of opioid misuse risk on the effectiveness of an opioid-minimizing multimodal pain regimen. The Opioid Risk Tool was useful in identifying high-risk patients for whom the Multimodal Analgesic Strategies for Trauma multimodal pain regimen is recommended for perioperative pain management.
- | morphine sulphate / Generic mfg.
Preclinical, Journal: Regulation of the Endogenous Opiate Signaling Pathway against Oxidative Stress and Inflammation: A Considerable Approach for Exploring Preclinical Treatment of Parkinson's Disease. (Pubmed Central) - Nov 27, 2023
However, high concentrations of THP, a precursor of the morphine biosynthetic pathway, induced cell death, indicating the physiological importance of morphine biosynthesis in neural tissues. Thus, understanding the morphine biosynthetic pathway coupled with a NO signaling mechanism as a molecular target for neuroprotection against oxidative stress and inflammation in other preclinical models of PD is warranted.
- || P2 data, Journal: Long-term, continuous infusion of single-agent dinutuximab beta for relapsed/refractory neuroblastoma: an open-label, single-arm, Phase 2 study. (Pubmed Central) - Nov 27, 2023
P2
Thus, understanding the morphine biosynthetic pathway coupled with a NO signaling mechanism as a molecular target for neuroprotection against oxidative stress and inflammation in other preclinical models of PD is warranted. Long-term continuous infusion of single-agent dinutuximab beta is tolerable and associated with clinically meaningful responses in patients with relapsed/refractory high-risk neuroblastoma.
- | morphine sulphate / Generic mfg., tramadol hydrochloride / Generic mfg.
Journal: Evaluation of audit and feedback to family physicians on prescribing of opioid analgesics to opioid-na (Pubmed Central) - Nov 27, 2023
Long-term continuous infusion of single-agent dinutuximab beta is tolerable and associated with clinically meaningful responses in patients with relapsed/refractory high-risk neuroblastoma. Portrait had no impact on FPs' rates of prescribing opioid analgesics to opioid-na
- | Olinvyk (oliceridine) / Trevena
Preclinical, Journal: Assessment of the potential of novel and classical opioids to induce respiratory depression in mice. (Pubmed Central) - Nov 27, 2023
In addition to providing effective anti-nociception, the novel opioids, oliceridine, tianeptine and SR-17018 depress respiration in male mice. However, the different potencies and kinetics of effect between these novel opioids may be relevant to their therapeutic application in different clinical settings.
- | morphine sulphate / Generic mfg.
Journal: Transmuscular Quadratus Lumborum Block Does Not Provide Significant Benefit for Primary Hip Arthroscopy with Pericapsular Infiltration: A Randomized Control Trial. (Pubmed Central) - Nov 27, 2023
TQLB and PCI do not improve postoperative pain scores or total opioid consumption compared to PCI alone. TQLB may decrease the amount of intraoperative opiate usage.
- || morphine sulphate / Generic mfg.
Review, Journal: Patient-targeted interventions for opioid deprescribing: An overview of systematic reviews. (Pubmed Central) - Nov 27, 2023
TQLB may decrease the amount of intraoperative opiate usage. Evidence is too uncertain to draw firm conclusions about specific populations who may derive the greatest benefit from opioid deprescribing, warranting further investigation.
- | morphine sulphate / Generic mfg., dexmedetomidine / Generic mfg.
Trial completion: Intrathecal Morphine Versus Morphine-dexmedetomidine Combination for Postoperative Pain Control After Total Knee Replacement (clinicaltrials.gov) - Nov 27, 2023
P=N/A, N=105, Completed, Sponsor: Tanta University
Evidence is too uncertain to draw firm conclusions about specific populations who may derive the greatest benefit from opioid deprescribing, warranting further investigation. Not yet recruiting --> Completed
- | metamizole / Generic mfg., morphine sulphate / Generic mfg., ropivacaine / Generic mfg.
Trial completion, Enrollment change: TAP vs QLB in Patients After Cesarean Delivery (clinicaltrials.gov) - Nov 27, 2023
P4, N=105, Completed, Sponsor: Medical University of Lublin
Not yet recruiting --> Completed Unknown status --> Completed | N=200 --> 105
- | morphine sulphate / Generic mfg.
Journal: A novel device for the determination of liposome/water partition coefficients. (Pubmed Central) - Nov 26, 2023
Unknown status --> Completed | N=200 --> 105 The value of log P
- || morphine sulphate / Generic mfg.
Journal, Adverse drug reaction: Study on the association between adverse drug reactions to opioids and gene polymorphisms: a case-case-control study. (Pubmed Central) - Nov 26, 2023
The value of log P Polymorphism of ABCB1 (062rs1045642) is related to ADRs caused by oxycodone, and the incidence of ADRs is higher with the allele T. Polymorphism of ABCB1 is expected to become a clinical predictor of ADRs to oxycodone, and attention should be given to the occurrence of serious ADRs in patients with ABCB1 (062rs1045642) CT and TT genotypes.
- || morphine sulphate / Generic mfg.
Review, Journal: Repurposing EGFR Inhibitors for Oral Cancer Pain and Opioid Tolerance. (Pubmed Central) - Nov 25, 2023
Polymorphism of ABCB1 (062rs1045642) is related to ADRs caused by oxycodone, and the incidence of ADRs is higher with the allele T. Polymorphism of ABCB1 is expected to become a clinical predictor of ADRs to oxycodone, and attention should be given to the occurrence of serious ADRs in patients with ABCB1 (062rs1045642) CT and TT genotypes. We also propose that EGFR interaction with the
- || morphine sulphate / Generic mfg.
Clinical, Journal, Video, Surgery: Pulmonary Lobectomy for Early-Stage Lung Cancer with Uniportal versus Three-Portal Video-Assisted Thoracic Surgery: Results from a Single-Centre Randomized Clinical Trial. (Pubmed Central) - Nov 25, 2023
The mean cumulative morphine consumption (CMC) in the U-VATS Group after 7 days was lower than in the T-VATS Group (77.4 mg vs. 90.1 mg, p = 0.003)...The 30-day intercostal neuralgia rate was lower in the U-VATS Group, without reaching statistical significance. Patients undergoing U-VATS showed a lower analgesic consumption compared with the T-VATS Group; analgesic consumption was moderate in both groups.
- | Symproic (naldemedine) / Shionogi, Collegium Pharma
Journal: Influence of Brain Metastasis on Analgesia-Related Outcomes in Patients with Lung and Breast Cancers Treated with Naldemedine: A Propensity Score-Matched Analysis. (Pubmed Central) - Nov 25, 2023
BM does not influence the analgesic effect of opioids in patients with lung and breast cancers treated with naldemedine. Naldemedine may be useful for treating BM.
- | morphine sulphate / Generic mfg.
Journal: Community Opioid Dispensing after Injury (CODI): Cohort characteristics and opioid dispensing patterns. (Pubmed Central) - Nov 25, 2023
This is a novel population-level profile of opioid dispensing patterns following injury-related hospitalisation, described for the time period prior to the implementation of opioid stewardship programs and regulatory changes in Queensland. Detailed understanding of this pre-implementation period is critical for evaluating the impact of these changes moving forward.
- | morphine sulphate / Generic mfg., papaverine / Generic mfg.
Journal: Comparison of direct analysis in real-time mass spectrometry, atmospheric solids analysis probe-mass spectrometry, and ion mobility spectrometry for ensuring food safety by rapid screening of poppy seeds. (Pubmed Central) - Nov 24, 2023
These instruments have been used to analyze 17 poppy seed samples for the presence of alkaloids, and the results were compared to data obtained using liquid chromatography with mass spectral detection (LC-MS/MS). Results from the 17 poppy seed samples indicate that the DART-MS, ASAP-MS, and IMS devices detect many of the same alkaloids confirmed during the LC-MS/MS analyses, although both the false-positive and false-negative rates are higher, possibly due to the non-homogeneity of the samples and the lack of chromatographic separation.
- || Chirocaine (levobupivacaine) / Purdue, AbbVie
Review, Journal: Postoperative Pain Management in Coronary Artery Bypass Grafting: An Integrative Review. (Pubmed Central) - Nov 24, 2023
The drugs used demonstrated efficacy and safety in the treatment of pain, with the exception of nefopam, which showed little benefit in this population. Nonpharmacological interventions, used as adjuvants to drug treatment, were shown to be safe, effective, and well tolerated by the patients.
- || morphine sulphate / Generic mfg.
Retrospective data, Review, Journal, Surgery: Efficacy and safety of perioperative use of non-steroidal anti-inflammatory drugs for preemptive analgesia in lumbar spine surgery: a systematic review and meta-analysis. (Pubmed Central) - Nov 24, 2023
Nonpharmacological interventions, used as adjuvants to drug treatment, were shown to be safe, effective, and well tolerated by the patients. Our findings suggest that NSAIDs are effective and safe for preemptive analgesia in the perioperative period of lumbar spine surgery and that more and better quality RCTs and more in-depth studies of pain mechanics are still needed.
- | morphine sulphate / Generic mfg.
Retrospective data, Journal, Surgery: A Prescribing Guideline Decreases Postoperative Opioid Prescribing in Emergency General Surgery. (Pubmed Central) - Nov 24, 2023
Our findings suggest that NSAIDs are effective and safe for preemptive analgesia in the perioperative period of lumbar spine surgery and that more and better quality RCTs and more in-depth studies of pain mechanics are still needed. A departmental guideline to standardize postoperative opioid prescriptions was associated with a decrease in the amount of MMEs prescribed to EGS patients without an increase in requested or received refills.
- | morphine sulphate / Generic mfg., papaverine / Generic mfg.
Observational data, Journal: A cluster of acute thebaine poisonings from non-food grade poppy seeds in the Australian food supply. (Pubmed Central) - Nov 22, 2023
Thebaine toxicity, like strychnine poisoning, resulted in neuromuscular excitation characterized by muscle spasm, rigidity, and convulsions. Severe toxicity, including acute kidney injury, metabolic acidosis, and cardiac arrest, appears dose-dependent.
- ketorolac / Generic mfg.
The Effect of Ketorolac on Pediatric Bone Healing Rate following Osteotomy in Patients with Deformity or Limb Length Discrepancy (South, Esplanade Ballroom 153) - Nov 22, 2023 - Abstract #AAOS2024AAOS_3157;
The total amount of opioids used, calculated as the morphine milligram equivalent (MME), as well as the total amount of ketorolac used in the perioperative period, was determined for each patient. The use of ketorolac did not result in an increased time to healing in patients who had osteoplasty for deformity correction or limb lengthening.
- Exparel (bupivacaine liposome injectable suspension) / Pacira
Liposomal Bupivacaine Does Not Decrease Postoperative Pain in Patients with Intracapsular Femoral Neck Fracture Treated with Hemiarthroplasty: A Double-Blinded Randomized, Controlled Trial (South, Esplanade Ballroom 155) - Nov 22, 2023 - Abstract #AAOS2024AAOS_3098;
The results of our study suggest use of liposomal bupivacaine is not associated with significantly improved postoperative pain, function, or shorter hospital course relative to saline following hip hemiarthroplasty for femoral neck fractures. Given the cost of liposomal bupivacaine over standard postoperative pain modalities, it is worth examining its use in the setting of geriatric hip fractures.
- morphine sulphate / Generic mfg.
Opioid-Free Perioperative Pain Protocol Provides Non-Inferior Pain Control Compared to Traditional Opioid-Containing Perioperative Pain Management in Patients undergoing Elective Orthopaedic Surgery (South, Room 210) - Nov 22, 2023 - Abstract #AAOS2024AAOS_3019;
This research reveals that an opioid-free perioperative pain protocol is safe, effective, and should be strongly considered in interested patients undergoing elective orthopaedic surgery. Further work needs to be done to demonstrate its scalability in various subspecialties and procedures outside of elective orthopaedic surgery procedures studied as well as its effectiveness in various patient populations to better outline the extent of its indications.
- morphine sulphate / Generic mfg.
Liposomal Bupivacaine + Bupivacaine versus Bupivacaine Interscalene Nerve Block Effect on Pain after Arthroscopic Rotator Cuff Repair: A Randomized Control Trial (West, Room 2001) - Nov 22, 2023 - Abstract #AAOS2024AAOS_2948;
The use of liposomal bupivacaine in ISBs does not lead to a significant difference in opioid consumption and VAS scores compared to standard bupivacaine during the first 14 days following rotator cuff repair or arthroscopy shoulder surgery except for on postoperative day 2. Consideration should therefore be taken into whether the use of liposomal bupivacaine is cost effective given its higher cost compared to bupivacaine.
- ketorolac / Generic mfg., morphine sulphate / Generic mfg.
Effective Local Wound Infiltration with Morphine, Ketorolac, and Bupivacaine following Lower Extremities Tendon Surgery in Pediatric Patients: A Stratified Randomized Controlled Trial (South, Esplanade Ballroom 153) - Nov 22, 2023 - Abstract #AAOS2024AAOS_2831;
Consideration should therefore be taken into whether the use of liposomal bupivacaine is cost effective given its higher cost compared to bupivacaine. Multimodal wound infiltration using bupivacaine, ketorolac, and morphine did not yield any clinically important reduction in postoperative pain or opioid consumption compared with bupivacaine alone in pediatric patients who underwent lower extremities tendon surgery.
- morphine sulphate / Generic mfg.
Is Robotically-Assisted Total Knee Arthroplasty Associated with Improved Early Recovery? A Prospective Cohort Study Utilizing Daily Remote Monitoring (West, Room 2001) - Nov 22, 2023 - Abstract #AAOS2024AAOS_2797;
All patients utilized a wrist-based activity monitor and a smartphone app-based patient engagement platform for one week preoperatively and 90 days postoperatively to collect daily step counts, Visual Analog Scale (VAS) pain scores, opioid consumption (milligram morphine equivalent; [MME]), weekly Oxford Knee Score (OKS), and monthly Forgotten Joint Score (FJS)... Utilizing daily remote patient monitoring, we found that robotic-assistance in TKA led to incremental improvements in pain, opioid consumption, and OKS scores compared to manual instrumentation in the early recovery after primary TKA.
- morphine sulphate / Generic mfg.
Regional Anesthesia is Safe for Use in Nailing of Tibial Shaft Fractures (OrthoLive, West Hall) - Nov 22, 2023 - Abstract #AAOS2024AAOS_2025;
Regional anesthesia in tibial shaft fracture surgery led to shorter time in the operating room with less intraoperative opioid requirements, without any untoward effects. Peripheral nerve blocks can be safely utilized in closed tibial shaft fractures in order to decrease opioid usage.
- morphine sulphate / Generic mfg.
Spinal versus General Anesthesia for Outpatient Total Hip and Knee Arthroplasty in the Ambulatory Surgery Center: A Matched-Cohort Study (OrthoLive, West Hall) - Nov 22, 2023 - Abstract #AAOS2024AAOS_1970;
General endotracheal anesthesia had an acceptable rate of SDD and 90-day complications and was associated with faster discharge from the ASC with earlier time to ambulation and urination postoperatively. These patients experienced more pain and nausea compared to those with spinal anesthesia.