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7 Diseases |  |
379 Trials |
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379 Trials |  |
12426 News |  |
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- | Sufenta (sufentanil) / Akorn
Enrollment open, Surgery: Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement) (clinicaltrials.gov) - Jul 7, 2020
P4, N=1000, Recruiting, Sponsor: Duke University
Suspended --> Recruiting
- | morphine sulphate / Generic mfg., ketamine / Generic mfg.
Phase classification, Trial completion date, Trial initiation date, Trial primary completion date: Comparison Between Low-dose Ketamine Infusion and Intravenous Morphine (clinicaltrials.gov) - Jul 7, 2020
P4, N=80, Enrolling by invitation, Sponsor: Cairo University
Suspended --> Recruiting Phase classification: P1 --> P4 | Trial completion date: May 2020 --> Aug 2020 | Initiation date: Sep 2015 --> Feb 2020 | Trial primary completion date: Mar 2020 --> Aug 2020
- | morphine sulphate / Generic mfg., dexmedetomidine / Generic mfg.
Enrollment open, Surgery: Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia. (clinicaltrials.gov) - Jul 6, 2020
P=N/A, N=50, Recruiting, Sponsor: Cairo University
Phase classification: P1 --> P4 | Trial completion date: May 2020 --> Aug 2020 | Initiation date: Sep 2015 --> Feb 2020 | Trial primary completion date: Mar 2020 --> Aug 2020 Not yet recruiting --> Recruiting
- | morphine sulphate / Generic mfg., dexmedetomidine / Generic mfg.
Journal: Effect of combinations of morphine, dexmedetomidine and maropitant on the electroencephalogram in response to acute electrical stimulation in anaesthetized dogs. (Pubmed Central) - Jul 3, 2020
There was no correlation of the changes in EEG frequencies with blood plasma concentration of the drugs during and after noxious stimulation. Combination of dexmedetomidine and morphine was most effective in abolishing the changes in EEG indices in response to a noxious stimulus indicating a supra-additive interaction between these two drugs.
- | morphine sulphate / Generic mfg.
New P3 trial, HEOR, Cost effectiveness: Morphine And BrEathLessness trial (MABEL) (EUDRACT) - Jul 2, 2020
P3, N=158, Ongoing, Sponsor: Hull University Teaching Hospitals NHS Trust
- | morphine sulphate / Generic mfg.
Trial completion date, Trial primary completion date: Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery (clinicaltrials.gov) - Jul 2, 2020
P4, N=140, Recruiting, Sponsor: Icahn School of Medicine at Mount Sinai
Combination of dexmedetomidine and morphine was most effective in abolishing the changes in EEG indices in response to a noxious stimulus indicating a supra-additive interaction between these two drugs. Trial completion date: Sep 2020 --> Dec 2020 | Trial primary completion date: Jul 2020 --> Dec 2020
- | morphine sulphate / Generic mfg.
New P3 trial: Randomized Control Trial of Buprenorphine vs. Morphine for the Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS) (clinicaltrials.gov) - Jul 1, 2020
P3, N=132, Not yet recruiting, Sponsor: Women and Infants Hospital of Rhode Island
- | morphine sulphate / Generic mfg., dexmedetomidine / Generic mfg.
New trial, Surgery: The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer Surgery (clinicaltrials.gov) - Jul 1, 2020
P=N/A, N=60, Not yet recruiting, Sponsor: National Taiwan University Hospital
- | morphine sulphate / Generic mfg.
Enrollment closed: Effect of Intrathecal Morphine on Chronic Pain After Elective Caesarean Section (clinicaltrials.gov) - Jul 1, 2020
P4, N=290, Active, not recruiting, Sponsor: B.P. Koirala Institute of Health Sciences
Trial completion date: Sep 2020 --> Dec 2020 | Trial primary completion date: Jul 2020 --> Dec 2020 Recruiting --> Active, not recruiting
- | morphine sulphate / Generic mfg., ketamine / Generic mfg.
Enrollment change, Trial completion date, Trial primary completion date: Ketamine Versus Morphine Change Pain Profile (clinicaltrials.gov) - Jun 29, 2020
P=N/A, N=160, Completed, Sponsor: Cairo University
Recruiting --> Active, not recruiting N=80 --> 160 | Trial completion date: Jan 2019 --> Jan 2020 | Trial primary completion date: Dec 2018 --> Dec 2019
- | morphine sulphate / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date: Genetic Variation in Organic Cation Transport 1 (OCT1) and Its Significance for Morphine Pharmacokinetics (clinicaltrials.gov) - Jun 28, 2020
P1, N=86, Completed, Sponsor: University of Southern Denmark
N=80 --> 160 | Trial completion date: Jan 2019 --> Jan 2020 | Trial primary completion date: Dec 2018 --> Dec 2019 Not yet recruiting --> Completed | Trial completion date: Jul 2021 --> Feb 2020 | Trial primary completion date: Jul 2021 --> Feb 2020
- || ASP8062 / Astellas
New P1 trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dose of Morphine in Recreational Opioid Using Participants (clinicaltrials.gov) - Jun 25, 2020
P1, N=24, Recruiting, Sponsor: Astellas Pharma Global Development, Inc.
- | morphine sulphate / Generic mfg., dexmedetomidine / Generic mfg.
New trial, Surgery: Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia. (clinicaltrials.gov) - Jun 23, 2020
P=N/A, N=50, Not yet recruiting, Sponsor: Cairo University
- | Penthrox (methoxyflurane) / Medical Developments International
New P4 trial: METHANE: Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris (clinicaltrials.gov) - Jun 23, 2020
P4, N=75, Recruiting, Sponsor: Collegium Medicum w Bydgoszczy
- | morphine sulphate / Generic mfg., midazolam hydrochloride / Generic mfg.
Trial completion, Trial primary completion date: SHARP: Shaping Anesthetic Techniques to Reduce Post-operative Delirium (clinicaltrials.gov) - Jun 18, 2020
P=N/A, N=218, Completed, Sponsor: Johns Hopkins University
Not yet recruiting --> Completed | Trial completion date: Jul 2021 --> Feb 2020 | Trial primary completion date: Jul 2021 --> Feb 2020 Trial primary completion date: Jun 2019 --> May 2020 | Active, not recruiting --> Completed
- | methadone / Generic mfg.
Enrollment change, Trial primary completion date: Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Laparoscopic Hysterectomy (clinicaltrials.gov) - Jun 17, 2020
P=N/A, N=126, Recruiting, Sponsor: University of Aarhus
Trial primary completion date: Jun 2019 --> May 2020 | Active, not recruiting --> Completed N=250 --> 126 | Trial primary completion date: Sep 2021 --> Dec 2021
- | morphine sulphate / Generic mfg.
Trial completion date, Trial primary completion date: MoreFoRCOPD: Morphine or Fentanyl for Refractory Dyspnea in COPD (clinicaltrials.gov) - Jun 16, 2020
P4, N=60, Recruiting, Sponsor: Huib A.M. Kerstjens
N=250 --> 126 | Trial primary completion date: Sep 2021 --> Dec 2021 Trial completion date: Sep 2020 --> Apr 2021 | Trial primary completion date: Jun 2020 --> Jan 2021
- | morphine sulphate / Generic mfg., gabapentin / Generic mfg.
New P1/2 trial, Surgery: Preemptive Oral Gabapentin 600 mg in Reducing Morphine Requirement After Non Obstetric Lower Abdominal Surgery (clinicaltrials.gov) - Jun 16, 2020
P1/2, N=72, Completed, Sponsor: Indonesia University
- | morphine sulphate / Generic mfg.
New P3 trial: PAciFy Cough: Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis Cough (clinicaltrials.gov) - Jun 12, 2020
P3, N=44, Not yet recruiting, Sponsor: Royal Brompton & Harefield NHS Foundation Trust
- | morphine sulphate / Generic mfg.
New P1/2 trial: MORPHEUS I/IIa: Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa (clinicaltrials.gov) - Jun 11, 2020
P1/2, N=24, Not yet recruiting, Sponsor: University Hospital, Grenoble
- | morphine sulphate / Generic mfg.
Enrollment open: PctIbfFKUI: Effect of Paracetamol and Ibuprofen Reducing Morphine Requirements After Total Knee Arthroplasty (clinicaltrials.gov) - Jun 9, 2020
P2/3, N=36, Recruiting, Sponsor: Indonesia University
Trial completion date: Sep 2020 --> Apr 2021 | Trial primary completion date: Jun 2020 --> Jan 2021 Not yet recruiting --> Recruiting
- | dexamethasone / Generic mfg., morphine sulphate / Generic mfg.
Enrollment open: RECIPE: Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty (clinicaltrials.gov) - Jun 8, 2020
P4, N=1060, Recruiting, Sponsor: Naestved Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- | morphine sulphate / Generic mfg.
New P2/3 trial: PctIbfFKUI: Effect of Paracetamol and Ibuprofen Reducing Morphine Requirements After Total Knee Arthroplasty (clinicaltrials.gov) - Jun 4, 2020
P2/3, N=36, Not yet recruiting, Sponsor: Indonesia University
- | morphine sulphate / Generic mfg., epinephrine / Generic mfg.
Trial completion date, Trial primary completion date: Surgicel and Analgesic Reservoir (clinicaltrials.gov) - Jun 2, 2020
P2/3, N=90, Recruiting, Sponsor: Assiut University
Not yet recruiting --> Recruiting Trial completion date: Dec 2019 --> Jun 2020 | Trial primary completion date: Dec 2019 --> Jun 2020
- | morphine sulphate / Generic mfg.
Trial completion date, Trial primary completion date: Effect of Intrathecal Morphine on Chronic Pain After Elective Caesarean Section (clinicaltrials.gov) - Jun 1, 2020
P4, N=290, Recruiting, Sponsor: B.P. Koirala Institute of Health Sciences
Trial completion date: Dec 2019 --> Jun 2020 | Trial primary completion date: Dec 2019 --> Jun 2020 Trial completion date: Jun 2020 --> Dec 2020 | Trial primary completion date: Apr 2020 --> Dec 2020
- | ketorolac / Generic mfg., morphine sulphate / Generic mfg., hydromorphone hydrochloride / Generic mfg.
Trial initiation date: PATIENCE: Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid (clinicaltrials.gov) - Jun 1, 2020
P2, N=50, Not yet recruiting, Sponsor: Boston Children
Trial completion date: Jun 2020 --> Dec 2020 | Trial primary completion date: Apr 2020 --> Dec 2020 Initiation date: Feb 2020 --> Jul 2020
- | Sufenta (sufentanil) / Akorn
Trial primary completion date: Plasmatic Catecholamines: Randomized Controlled Trial Comparing Epidural Versus Combined Spinal-epidural (clinicaltrials.gov) - May 29, 2020
P=N/A, N=74, Recruiting, Sponsor: University of Sao Paulo General Hospital
Initiation date: Feb 2020 --> Jul 2020 Trial primary completion date: Dec 2019 --> Dec 2020
- | morphine sulphate / Generic mfg.
Enrollment open: Open Radical Prostatectomy and Erector Spinae Plane Block (clinicaltrials.gov) - May 28, 2020
P=N/A, N=50, Recruiting, Sponsor: BURHAN DOST
Trial primary completion date: Dec 2019 --> Dec 2020 Not yet recruiting --> Recruiting
- | morphine sulphate / Generic mfg.
New P4 trial: Sequential and Mixture Injection of Opioids and Hyperbaric Bupivacaine (clinicaltrials.gov) - May 26, 2020
P4, N=126, Not yet recruiting, Sponsor: Assiut University
- | morphine sulphate / Generic mfg., ketamine / Generic mfg.
Trial completion date, Trial primary completion date: KETAMORPH: Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia (clinicaltrials.gov) - May 21, 2020
P3, N=496, Recruiting, Sponsor: Nantes University Hospital
Not yet recruiting --> Recruiting Trial completion date: May 2020 --> May 2022 | Trial primary completion date: May 2020 --> May 2022
- | morphine sulphate / Generic mfg.
New trial, Surgery: Cervical Erector Spinae Block for Shoulder Surgery (clinicaltrials.gov) - May 21, 2020
P=N/A, N=60, Not yet recruiting, Sponsor: Konya Necmettin Erbakan
- | morphine sulphate / Generic mfg.
New P4 trial: Intraosseous Morphine in Primary TKA (clinicaltrials.gov) - May 13, 2020
P4, N=84, Recruiting, Sponsor: The Methodist Hospital System
- | morphine sulphate / Generic mfg.
New trial: REHACESAR: Impact of a Strategy Combining Morphine Savings and Anesthesia Technique on the Quality of Post-operative Rehabilitation (clinicaltrials.gov) - May 6, 2020
P, N=450, Recruiting, Sponsor: Centre Hospitalier R
- | morphine sulphate / Generic mfg.
New P4 trial: Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine (clinicaltrials.gov) - Apr 30, 2020
P4, N=80, Not yet recruiting, Sponsor: The University of Texas Health Science Center, Houston
- | morphine sulphate / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date: Therapeutic Rest to Delay Admission in Early Labor: A Prospective Study on Morphine Sleep (clinicaltrials.gov) - Apr 29, 2020
P=N/A, N=81, Completed, Sponsor: University of California, San Francisco
Trial completion date: May 2020 --> May 2022 | Trial primary completion date: May 2020 --> May 2022 Recruiting --> Completed | Trial completion date: Jul 2021 --> Apr 2020 | Trial primary completion date: Jul 2020 --> Apr 2020
- | morphine sulphate / Generic mfg.
New P4 trial: A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain (clinicaltrials.gov) - Apr 29, 2020
P4, N=75, Not yet recruiting, Sponsor: The University of Texas Health Science Center, Houston
- | morphine sulphate / Generic mfg.
Enrollment closed: Ultrasound Guided Femoral Nerve Block (clinicaltrials.gov) - Apr 28, 2020
P=N/A, N=60, Active, not recruiting, Sponsor: Beth Israel Deaconess Medical Center
Recruiting --> Completed | Trial completion date: Jul 2021 --> Apr 2020 | Trial primary completion date: Jul 2020 --> Apr 2020 Recruiting --> Active, not recruiting
- | morphine sulphate / Generic mfg.
Enrollment change, Surgery: Perioperative Pain Management In Spine Surgery Patients: Part I (clinicaltrials.gov) - Apr 27, 2020
P=N/A, N=100, Completed, Sponsor: Allina Health System
Recruiting --> Active, not recruiting N=151 --> 100
- | morphine sulphate / Generic mfg., hydromorphone hydrochloride / Generic mfg.
Trial completion date, Trial primary completion date: NCI-2018-01139: Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer (clinicaltrials.gov) - Apr 24, 2020
P1, N=86, Recruiting, Sponsor: M.D. Anderson Cancer Center
N=151 --> 100 Trial completion date: Jan 2020 --> Jan 2021 | Trial primary completion date: Jan 2020 --> Jan 2021
- | morphine sulphate / Generic mfg.
New P2 trial: Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS) (clinicaltrials.gov) - Apr 23, 2020
P2, N=22, Not yet recruiting, Sponsor: Assistance Publique - H
- | morphine sulphate / Generic mfg.
Enrollment change, Trial completion date, Trial withdrawal, Trial primary completion date: Randomized, Double-blind, Placebo, Controlled Cross Over Design Topical Morphine for Analgesia in Pediatric Procedures (clinicaltrials.gov) - Apr 22, 2020
P4, N=0, Withdrawn, Sponsor: Hospital General de Niños Pedro de Elizalde
Trial completion date: Jan 2020 --> Jan 2021 | Trial primary completion date: Jan 2020 --> Jan 2021 N=44 --> 0 | Trial completion date: Dec 2018 --> Apr 2020 | Recruiting --> Withdrawn | Trial primary completion date: Nov 2018 --> Apr 2020
- | morphine sulphate / Generic mfg.
Trial completion, Video: Robot-assisted Lobectomy Versus Video-assisted Lobectomy (clinicaltrials.gov) - Apr 22, 2020
P=N/A, N=200, Completed, Sponsor: Hospital Nord
N=44 --> 0 | Trial completion date: Dec 2018 --> Apr 2020 | Recruiting --> Withdrawn | Trial primary completion date: Nov 2018 --> Apr 2020 Recruiting --> Completed
- | morphine sulphate / Generic mfg., methadone / Generic mfg.
Trial initiation date: Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS) (clinicaltrials.gov) - Apr 21, 2020
P3, N=502, Not yet recruiting, Sponsor: Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program
Recruiting --> Completed Initiation date: Apr 2020 --> Aug 2020
- | Sufenta (sufentanil) / Akorn
Trial suspension, Surgery: Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement) (clinicaltrials.gov) - Apr 20, 2020
P4, N=1000, Suspended, Sponsor: Duke University
Initiation date: Apr 2020 --> Aug 2020 Recruiting --> Suspended
- || morphine sulphate / Generic mfg.
Enrollment closed: Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain (clinicaltrials.gov) - Apr 20, 2020
P4, N=100, Active, not recruiting, Sponsor: MedtronicNeuro
Recruiting --> Suspended Recruiting --> Active, not recruiting
- | morphine sulphate / Generic mfg.
Enrollment open: A Relation of Morphine-induced Itch and Pain Processing (clinicaltrials.gov) - Apr 20, 2020
P=N/A, N=24, Recruiting, Sponsor: Aalborg University
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- | morphine sulphate / Generic mfg.
Trial completion: Nebulized Morphine in Chest Trauma Patients: A Prospective Study (clinicaltrials.gov) - Apr 16, 2020
P3, N=75, Completed, Sponsor: University Hospital, Mahdia
Not yet recruiting --> Recruiting Recruiting --> Completed
- | morphine sulphate / Generic mfg.
Enrollment closed, Surgery: 24-hour Oral Morphine Equivalent Based Opioid Prescribing After Surgery (clinicaltrials.gov) - Apr 13, 2020
P=N/A, N=54, Active, not recruiting, Sponsor: University of Colorado, Denver
Recruiting --> Completed Recruiting --> Active, not recruiting
- | morphine sulphate / Generic mfg.
Enrollment open, Surgery: Perioperative Analgesic Modalities for Breast Cancer Surgeries (clinicaltrials.gov) - Apr 13, 2020
P=N/A, N=50, Recruiting, Sponsor: National Cancer Institute, Egypt
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- | morphine sulphate / Generic mfg.
New P4 trial: Brain Effects of Opiate Agonist and Antagonist (clinicaltrials.gov) - Apr 10, 2020
P4, N=9, Completed, Sponsor: University of Rochester