morphine sulphate / Generic mfg. 
Welcome,         Profile    Billing    Logout  
 7 Diseases   379 Trials   379 Trials   12426 News 


«12...144145146147148149150151152153154...216217»
  • ||||||||||  morphine sulphate / Generic mfg.
    Retrospective data, Journal:  Fewer Ports Cut Opioid Use and Length of Stay in Elective Laparoscopic Cholecystectomy. (Pubmed Central) -  Oct 6, 2021   
    The smaller total cross-sectional area associated with the 3-port approach (12/5/5, 277.25 mm) resulted in significantly lower total oral morphine equivalent daily dose required compared to 12/10/5/5 (453.96 mm) and 12/5/5/5 (327.52 mm) approaches, being 30.7 mg and 21.0 mg less, respectively (p < 0.001)...The absolute number of ports used in elective laparoscopic cholecystectomies appears to play an important role in postoperative recovery. In particular, 3-port configurations may result in less postoperative pain without the burden of an increase in length of stay, morbidity, or mortality rates.
  • ||||||||||  morphine sulphate / Generic mfg., dexamethasone injection / Generic mfg.
    Clinical, Journal:  Dexamethasone as an Analgesic Adjunct for Postcesarean Delivery Pain: A Randomized Controlled Trial. (Pubmed Central) -  Oct 5, 2021   
    There were no differences between the groups in cumulative opioid consumption at 48 h, time to first analgesic request, and pain scores. Intravenous dexamethasone 8 mg administered prior to skin incision did not reduce the opioid consumption of women that underwent cesarean deliveries under spinal anesthesia with intrathecal morphine and multimodal postoperative analgesic regimen.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Palliative care and euthanasia: A Nepalese scenario. (Pubmed Central) -  Oct 5, 2021   
    However, since oral morphine is not available, pain control is often inadequate...Should euthanasia be legal? If cheap and effective palliative care were easily accessible, most terminally ill Nepalese would avoid pressure to practise euthanasia because it is a cheaper option.
  • ||||||||||  morphine sulphate / Generic mfg.
    New P4 trial:  Intrathecal Morphine for Cesarean Delivery (clinicaltrials.gov) -  Oct 5, 2021   
    P4,  N=72, Not yet recruiting, 
  • ||||||||||  morphine sulphate / Generic mfg., paracetamol / Generic mfg.
    [VIRTUAL] Does In-Hospital Pain Prescribing Inform Post-Operative Discharge? (Channel 2) -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_1966;    
    Despite national guidelines promoting multimodal painmanagement, this occurred in just half of patients undergoing simple generalsurgery procedures. Discharge opioid prescribing was not related to multimodaluse, yet patients' length of stay was lower with multimodal admission orders.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Opioid Prescribing Trends After Cholecystectomy, Thyroidectomy And Herniorrhaphy (Channel 2) -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_1965;    
    The type of surgery performed was the strongest influence on opioid prescribing. Therefore, we recommend optimizing current guidelines with periodical reviews to ensure patient receiving the proper and needed treatment with minimizing over and under-prescribing of narcotic pain medication.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Perioperative And Persistent Opioid Utilization Following Pancreatectomy (Channel 1) -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_1403;    
    Preoperative and persistent opioid use after pancreatectomy is substantially greater than expected based on other operations. Providers may mitigate this by recognizing the issue, managing expectations, and altering the timing and quantities of opioid prescribed.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Narx Scores In Bariatric Surgery: Characterizing Distribution And Predicting Emergency Room Visits () -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_1284;    
    We found that patients in the upper terciles for Narx scores had a score of 200 or higher, indicating an odds ratio of at least 10 for narcotic overdose. Patients in the upper tercile for Narx score were also more likely to have depression, anxiety, bipolar disorder, and preventable ER visits when compared to patients in the lower tercile.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Postoperative Delirium Among Patients Undergoing Major Abdominal Surgery Randomized To In-hospital Probiotics Or Placebo () -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_582;    
    Patients with delirium were more comorbid (Charlson comorbidity index 2.8±2.6 versus 4.2±3.0; p=0.048), experienced a prolonged time until solid diet intake (1.9±1.7 versus 8.9±15.7; p=0.003), had longer operative duration (247±93 versus 385±183; p=0.002), length of stay (4.2±3.0 versus 16.0±16.5; p<0.001), and twice higher total in-hospital morphine equivalent dose (107±84 versus 235±257; p=0.044)... Short-course perioperative VSL #3 probiotics did not influence rate of postoperative delirium in this post hoc analysis of randomized trial.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Predictors Of Opioid-free Discharge After Laparoscopic Cholecystectomy () -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_544;    
    Average pain score prior to discharge and average daily post-operative morphine equivalent (MEQ) use were higher in the opioid population, 5 vs. 3.7 (p<0.0001) and 152 vs. 30mg (p<0.0001)... Non-elective procedures, older age, and lower post-operative average daily MEQ are predictors of opioid-free discharge after laparoscopic cholecystectomy.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] The Effect Of Cryotherapy Application On Post-operative Pain: A Systematic Review And Meta-analysis () -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_541;    
    There was moderate certainty of evidence that cryotherapy results in reduction of opioid consumption in Morphine milliequivalents (MME) or MME/kg, (MD -7.43, 95%CI -12.42, -2.44) and (MD -0.89, 95%CI -1.45, -0.33) respectively. Cryotherapy application reduces post-operative pain and opioid consumption with no effect on SSI or length of stay in hospital compared to patients who did not receive cryotherapy.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Pain Management For Gender Confirmation Surgery In The Age Of The Opioid Overdose Epidemic (Channel 4) -  Oct 5, 2021 - Abstract #ACSCLINCON2021ACS_CLINCON_107;    
    In the initial cohort, the average daily MME administered for postoperative pain was 21.06 mg morphine (σ=15.23). Preemptive pain management with clinician-administered multimodal non-opioid analgesia in the acute postoperative setting was shown to decrease the number of opioids administered in recovery following vaginoplasty by nearly 60%.
  • ||||||||||  morphine sulphate / Generic mfg.
    Enrollment change, Trial withdrawal:  Evaluation of the Roll of IV Fluids in the Treatment of Renal Colic (clinicaltrials.gov) -  Oct 4, 2021   
    P4,  N=0, Withdrawn, 
    Intrathecal morphine is associated with earlier ambulation, shortened length of stay, and decreased post-operative narcotic use following pancreaticoduodenectomy. N=700 --> 0 | Not yet recruiting --> Withdrawn
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Polygenic Prediction of Response to Pharmacotherapy in Infants With Neonatal Opioid Withdrawal Syndrome () -  Oct 3, 2021 - Abstract #WCPG2021WCPG_661;    
    Clustering analyses revealed three possible response trajectories: immediate calming of withdrawal signs, a slightly delayed calming of withdrawal symptoms, or a failure to respond. We tested the hypothesis that response to pharmacotherapy can be predicted using polygenic risk scores (PRS) for opioid addiction derived from GWAS of opioid addiction in adults.
  • ||||||||||  morphine sulphate / Generic mfg.
    [VIRTUAL] Polygenic Prediction of Response to Pharmacotherapy in Infants With Neonatal Opioid Withdrawal Syndrome () -  Oct 3, 2021 - Abstract #WCPG2021WCPG_561;    
    Clustering analyses revealed three possible response trajectories: immediate calming of withdrawal signs, a slightly delayed calming of withdrawal symptoms, or a failure to respond. We tested the hypothesis that response to pharmacotherapy can be predicted using polygenic risk scores (PRS) for opioid addiction derived from GWAS of opioid addiction in adults.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Postoperative Opioid Prescribing Following Gynecologic Surgery for Pelvic Organ Prolapse. (Pubmed Central) -  Oct 3, 2021   
    Pain scores, opioid prescription amounts, and refills varied by patient age and surgical approach but were unaffected by concomitant procedures. Further work in correlating pain scores to opioid utilization is needed to ensure appropriate prescribing patterns and reduce risks of opioid dependence and diversion.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Pain intensity and imaging at the initial phase of acute pyelonephritis. (Pubmed Central) -  Oct 3, 2021   
    Further work in correlating pain scores to opioid utilization is needed to ensure appropriate prescribing patterns and reduce risks of opioid dependence and diversion. Pain requiring morphine use, age, and history of urolithiasis are independent predictors of urological complications on imaging findings in patients with acute pyelonephritis.
  • ||||||||||  pentylenetetrazole (BTD-001) / Balance Therap
    Preclinical, Journal:  Anticonvulsant Effects of Thalidomide on Pentylenetetrazole-Induced Seizure in Mice: A Role for Opioidergic and Nitrergic Transmissions. (Pubmed Central) -  Oct 2, 2021   
    Conversely, pretreatment with non-effective doses of either non-selective (L-NAME, 5 mg/kg, i.p.) or selective neuronal (7-nitroindazole, 30 mg/kg, i.p.) NO synthase (NOS) inhibitors significantly augmented the anticonvulsant effects of combined low doses of thalidomide and morphine, whereas the inducible NOS inhibitor aminoguanidine (100 mg/kg, i.p.) did not exert such effect. Our results indicate that opioidergic transmission and its interaction with neuronal NO signaling may contribute to the anti-seizure activity of thalidomide in the mice PTZ model of clonic seizure.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Effect of morphine on cerebral activity of extremely premature infants. (Pubmed Central) -  Oct 2, 2021   
    Our results indicate that opioidergic transmission and its interaction with neuronal NO signaling may contribute to the anti-seizure activity of thalidomide in the mice PTZ model of clonic seizure. Continuous infusion of morphine in extremely preterm infants significantly depresses their cerebral activity soon after its commencement.
  • ||||||||||  Octaplex (human prothrombin complex concentrate) / Octapharma, Pfizer
    Pain in the right leg. Analysis of a case. () -  Oct 1, 2021 - Abstract #EUSEM2021EUSEM_4421;    
    Retroperitoneal hematoma is a rare but potentially lethal entity that can present various clinical manifestations, which can be very non-specific with confusion in diagnosis and therefore delaying treatment. Having normal hemoglobin at onset does not always rule out active bleeding.