morphine sulphate / Generic mfg. 
Welcome,         Profile    Billing    Logout  
 7 Diseases   379 Trials   379 Trials   12426 News 


«12...132133134135136137138139140141142...217218»
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Intercostal cryoablation during Nuss procedure: A large volume single surgeon's experience and outcomes. (Pubmed Central) -  Dec 1, 2021   
    Our single surgeon experience controls for surgeon variability and demonstrates intraoperative IC for the Nuss procedure is an effective pain management modality that decreases hospital LOS and opioid use during hospitalization and at discharge; however, it is associated with increased odds of slipped bars requiring reoperation.
  • ||||||||||  morphine sulphate / Generic mfg.
    Preclinical, Journal:  The protective effect of zinc on morphine-induced testicular toxicity via p53 and Akt pathways: An in vitro and in vivo approach. (Pubmed Central) -  Dec 1, 2021   
    Our single surgeon experience controls for surgeon variability and demonstrates intraoperative IC for the Nuss procedure is an effective pain management modality that decreases hospital LOS and opioid use during hospitalization and at discharge; however, it is associated with increased odds of slipped bars requiring reoperation. The present data indicated the protective effect of zinc against morphine-induced testicular (Sertoli) cell toxicity via p53/Akt pathways in both in vivo and in vitro models and suggested the clinical importance of zinc on infertility among chronic opioid users and addicted men.
  • ||||||||||  duloxetine / Generic mfg.
    Clinical, Journal:  The Efficacy of Preoperative Duloxetine in Patients Undergoing Major Abdominal Cancer Surgery: A Randomized Controlled Trial. (Pubmed Central) -  Dec 1, 2021   
    The present data indicated the protective effect of zinc against morphine-induced testicular (Sertoli) cell toxicity via p53/Akt pathways in both in vivo and in vitro models and suggested the clinical importance of zinc on infertility among chronic opioid users and addicted men. A single preoperative dose of oral duloxetine, 60 mg for patients subjected to major abdominal cancer surgery reduced postoperative pain, decreased opioid consumption, and improved the quality of recovery.
  • ||||||||||  morphine sulphate / Generic mfg.
    Clinical, Journal:  Evaluation of topical morphine for treatment of oral mucositis in cancer patients. (Pubmed Central) -  Nov 30, 2021   
    No serious adverse events were reported. The findings indicate that the analgesic effect of peripherally applied morphine is not significantly different from placebo, and parenteral opioids should continue to be the standard of care.
  • ||||||||||  morphine sulphate / Generic mfg.
    Trial completion date, Trial primary completion date:  MoreFoRCOPD: Morphine or Fentanyl for Refractory Dyspnea in COPD (clinicaltrials.gov) -  Nov 30, 2021   
    P4,  N=60, Recruiting, 
    The findings indicate that the analgesic effect of peripherally applied morphine is not significantly different from placebo, and parenteral opioids should continue to be the standard of care. Trial completion date: Apr 2022 --> Dec 2022 | Trial primary completion date: Jan 2022 --> Oct 2022
  • ||||||||||  morphine sulphate / Generic mfg.
    Trial completion date, Trial primary completion date, Surgery:  Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery (clinicaltrials.gov) -  Nov 30, 2021   
    P=N/A,  N=20, Recruiting, 
    Trial completion date: Apr 2022 --> Dec 2022 | Trial primary completion date: Jan 2022 --> Oct 2022 Trial completion date: Apr 2021 --> Apr 2022 | Trial primary completion date: Apr 2021 --> Apr 2022
  • ||||||||||  morphine sulphate / Generic mfg.
    Trial completion date, Trial primary completion date:  Erector Spinae Plane Block for Post-nephrectomy Pain (clinicaltrials.gov) -  Nov 30, 2021   
    P=N/A,  N=60, Recruiting, 
    Trial completion date: Apr 2021 --> Apr 2022 | Trial primary completion date: Apr 2021 --> Apr 2022 Trial completion date: Nov 2021 --> Nov 2022 | Trial primary completion date: Oct 2021 --> May 2022
  • ||||||||||  morphine sulphate / Generic mfg.
    Clinical, Journal:  Inpatient Opioid Consumption Variability following Total Knee Arthroplasty: Analysis of 4,038 Procedures. (Pubmed Central) -  Nov 29, 2021   
    This study examined an early iteration of an inpatient opioid administration-reporting tool, which standardized patient opioid consumption as an average daily morphine milligram equivalence per surgical encounter (MME/day/encounter) among total knee arthroplasty (TKA) recipients...TKA candidates may benefit from the implementation of a more rigid standardization of multimodal pain management protocols that can control pain while minimizing the opioid burden. This is a level of evidence III, retrospective observational analysis.
  • ||||||||||  midazolam hydrochloride / Generic mfg.
    Journal:  Generalized convulsive status epilepticus after retrograde type A aortic dissection surgery. (Pubmed Central) -  Nov 29, 2021   
    Generalized convulsive status epilepticus should be alert for avoiding delay in the rehabilitation particularly after aortic dissection surgery. Under the good condition of ventilation, combining morphine with midazolam or diazepam can more effectively relieve the symptoms.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Modelling the risk of HIV infection for drug abusers. (Pubmed Central) -  Nov 29, 2021   
    Drug abusers often face a higher risk of acquiring HIV because target cell (CD4+ T-cell) receptor expression differs in response to morphine, a metabolite of common opiates...With in-depth understanding of the viral dynamics and the increased risk for these individuals, we further evaluate how preventive therapies, including pre- and post-exposure prophylaxis, affect the infection risk in drug abusers. These results are useful to devise ideal treatment protocols to combat the several obstacles those under drugs of abuse face.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Music and Medicine Come Together Over Pain in the Air Medical Transport Environment. (Pubmed Central) -  Nov 29, 2021   
    These results are useful to devise ideal treatment protocols to combat the several obstacles those under drugs of abuse face. Music may provide greater subjective pain relief when combined with NCHs in the air transport environment; further research is required.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal, Adverse events:  Initial opioid prescription patterns and the risk of ongoing use and adverse outcomes. (Pubmed Central) -  Nov 29, 2021   
    Buprenorphine 0.24 mg/kg SC for postoperative analgesia in cats was associated with hyperthermia that persisted for 16-20 h after administration, and the incidence of hyperthermia for this group was higher than in the cats that received morphine 0.1 mg/kg SC. Although the absolute risk of an opioid overdose within the first year of prescription opioid use is low, better alignment of opioid initiation practices with guidelines may reduce opioid-related harm.
  • ||||||||||  morphine sulphate / Generic mfg., paracetamol / Generic mfg.
    Journal:  Cooking heroin the Turkish way: chemical investigation on an unusual heroin preparation method. (Pubmed Central) -  Nov 29, 2021   
    Increasing the use of non-opioid pain management approaches, could constitute an important target in our efforts to curtail US opioid epidemic. The high amount of psychoactive 6-monoacetylmorphine may have an impact on the reported effects of heroin using the "Turkish" preparation procedure.
  • ||||||||||  midazolam hydrochloride / Generic mfg., dexmedetomidine / Generic mfg.
    Clinical, Journal:  Dexmedetomidine and Iatrogenic Withdrawal Syndrome in Critically Ill Children. (Pubmed Central) -  Nov 29, 2021   
    In this study, supplemental dexmedetomidine had no preventive effect on iatrogenic withdrawal syndrome in patients receiving sedative treatment in the pediatric intensive care unit. The cumulative dose of midazolam was a significant risk factor for iatrogenic withdrawal syndrome.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Interprofessional education on opioid use and pain identifies team-based learning needs. (Pubmed Central) -  Nov 29, 2021   
    Depending on profession, students demonstrated varied baseline knowledge regarding opioid use for chronic pain. Comparing knowledge gains and attitudes on IPE collaboration among professions can detect areas for program refinement to address each professions' unique needs.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Neonatal Abstinence Syndrome and Preterm Infants: A Look at Current Practice. (Pubmed Central) -  Nov 29, 2021   
    Ketamine-morphine PIVA might increase catecholamine activity. Future research describing the NAS symptomatology of preterm infants born at less than 34 weeks of gestational age exposed to intrauterine opioids is warranted.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Change in Opioid and Analgesic use for Headaches after Aneurysmal Subarachnoid Hemorrhage over Time. (Pubmed Central) -  Nov 29, 2021   
    Average oral morphine equivalents (in mg) administered during hospitalization were similar between groups (2012-2016: 251±345 95% CI [178,323]; 2017-2019: 207±237 95% CI [119,295]; P=0.319)...Maximal headache scores remained similar in the studied time periods, indicative of insufficient pain relief. This points out a pressing need to further investigate alternative opioid and narcotic sparing strategies for patients with SAH.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Dose-Dependent Early Postoperative Opioid Use Is Associated with Periprosthetic Joint Infection and Other Complications in Primary TJA. (Pubmed Central) -  Nov 29, 2021   
    This study showed that pain scores and morphine consumption, but not the side effects of patient-controlled analgesia during 24hours after the lumbar disk surgery, were significantly reduced by IV ibuprofen as a supplemental analgesic when compared with controls and paracetamols. Increasing opioid use within the early postoperative period following THA or TKA was associated with a dose-dependent increased risk of periprosthetic joint infection and venous thromboembolic events.
  • ||||||||||  morphine sulphate / Generic mfg., ropivacaine / Generic mfg., methadone / Generic mfg.
    Retrospective data, Journal:  Retrospective comparison of three locoregional techniques for pelvic limb surgery in dogs. (Pubmed Central) -  Nov 29, 2021   
    Intraoperative analgesia may be superior with EPI than SS for some surgeries of the pelvic limb, but not for stifle surgeries. All three techniques provided similar requirement for postoperative analgesia, but EPI caused higher incidence of intraoperative hypotension and postopertive urinary retention.
  • ||||||||||  morphine sulphate / Generic mfg.
    Retrospective data, Review, Journal:  Pelvic floor reconstructive surgery under local anesthesia: A systematic review and meta-analysis. (Pubmed Central) -  Nov 29, 2021   
    LA with or without sedation represents a safe and efficient alternative anesthetic technique for urogynecological procedures with improved pain scores in up to 18 h postoperatively especially in patients who underwent surgery for SUI. LA is feasible and could be offered to patients undergoing pelvic floor surgery allowing a prompt postoperative recovery.
  • ||||||||||  morphine sulphate / Generic mfg.
    Journal:  Long-Term Outcome of Spinal Cord Stimulation in Complex Regional Pain Syndrome. (Pubmed Central) -  Nov 29, 2021   
    Trial registration: The study was first registered at Clinicaltrials.gov on November 16, 2018 (identifier: NCT03743402). Despite the fact that CRPS patients were not able to discontinue or reduce their strong opioid or neuropathic pain medication use, 70% continued to use their SCS device during a median 8-yr follow-up.
  • ||||||||||  hydromorphone hydrochloride / Generic mfg.
    Review, Journal:  Hydromorphone for cancer pain. (Pubmed Central) -  Nov 29, 2021   
    There is insufficient evidence to support or refute the use of hydromorphone for cancer pain in comparison with other analgesics on the reported outcomes. Further research with larger sample sizes and more comprehensive outcome data collection is required.
  • ||||||||||  morphine sulphate / Generic mfg., hydromorphone hydrochloride / Generic mfg., isoflurane / Generic mfg.
    Journal:  Evaluation of perfusion index as a noninvasive tool to determine epidural anesthesia effectiveness in dogs. (Pubmed Central) -  Nov 29, 2021   
    Further research with larger sample sizes and more comprehensive outcome data collection is required. PI did not provide an objective means for determining the onset or effectiveness of epidural anesthesia in anesthetized dogs and alternate methods of noninvasive assessment should be investigated.