montelukast / Generic mfg. 
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122 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
montelukast / Generic mfg.
ChiCTR-TRC-07000028: Randomized controlled study of montelukast on patients with bronchiolitis

Completed
4
132
 
Regular treatment plus administration of montelukast for 7 days ;General regular treatment: anti-infection, oxygen uptake, cough suppression, sedation and inhalation therapy ofα2-receptor agonists ventolin ;Regular treatment and inhalation therapy of budesonide ;Regular treatment and inhalation therapy of Montelukast for 28 days
Postgraduate Department in the First Hospital Affiliated to Xinjiang Medical University; the First Hospital Affiliated to Xinjiang Medical University, Special fund for Evidence-Based Medicine in the First Hospital Affiliated to Xinjiang Medical College
Bronchiolitis
 
 
ChiCTR-TNRC-10000998: Impact of Smoking on Asthma and the Effect of Leukotriene Receptor Antagonist in asthma with smoking

Completed
4
37
 
Budesonide 200ug, inhalation, twice daily; salbutamol, inhalation, prn; Montelukast 10mg qn po. for 2 months ;Budesonide 200ug,inhalation, twice daily; salbutamol, inhalation, prn for 1month
Zhongshan Hospital, Fudan University; Level of the institution：, Zhongshan Hospital,Fudan University
asthma
 
 
ChiCTR-TRC-12002963: The Effcacy of Intranasal Budesonide and Leukotriene ModifierTherapy for Mild-moderate Pediatric Obstructive Sleep Apnean Hypopnea Syndrome

Completed
4
75
 
Montelukast Sodiuma 4mg or 5mg PO QN ;Rhinocort per puff per nostril to both nostrils b.i.d ;Rhinocort per puff per nostril to both nostrils b.i.d
The Fist Affiliated Hospital of Guangzhou Medical University; Level of the institution：, Principal Investigator Funds
Pediatric Obstructive Sleep Apnean Hypopnea Syndrome
 
 
ChiCTR-TRC-13003735: Add-on therapy with Montelukast in treatment of bronchiolitis

Completed
4
124
 
Add-on treatment with Montelukast ;Add-on treatment with Montelukast
Department of Pediatrics, The First Affiliated Hospital with Nanjing Medical University; The First Affiliated Hospital with Nanjing Medical University, Medical Emphasis Grant (No.56RC2002056) from Government of Jiangsu Province, China
bronchiolitis
 
 
ChiCTR-TRC-12002597: Clinical Study on the effects of add-on therapy with Montelukast in treatment of Henoch-Schnlein purpura

Completed
4
130
 
Routine treatment ;Routine treatment+Montelukast
Department of Pediatrics, First Affiliated Hospital of Nanjing Medical University; Department of Pediatrics, First Affiliated Hospital of Nanjing Medical University, Medical Emphasis Grant (No.56RC2002056) from Government of Jiangsu Province, China.
Henoch-Sch?nlein purpura(HSP)
 
 
2007-004541-15: A Randomized Controlled Open-Label Phase IV Mono Center Study to Compare the Reponse Profiles of Montelukast versus Fluticason in Children with Preschool Asthma

Ongoing
4
100
Europe
Singulair, Flutide, Singulair junior, Singulair mini 4mg Kautablette, Flutide mite 50 Dosier-Aerosol, Singulair junior 5mg Kautablette, Singulair mini 4mg Kautablette, Flutide mite 50 Dosier-Aerosol, Singulair junior 5mg Kautablette
Johann Wolfgang Goethe-Universität Frankfurt am Main
bronchial asthma is a very common medical problem in 3-7 year old children, often requiring hospitalization and demanding treatment on demand or permanently. Our trial is to compare to established treatment regimens with regard to their clinical efficacy
 
 
2005-001997-29: A Proof of Concept Study into the Effects on Inhlaed Extra-Fine and Standard Formulations of Beclomethasone Dipropionate and Oral Montelukast on Surrogate Markers of Small and Large Airway Inflammation in Asthma

Ongoing
4
30
Europe
Beclazone, QVAR, Singulair, Beclazone, QVAR, Singulair
University of Dundee
Asthma
 
 
2005-004115-29: Investigation to identify predictors of response to a treatment with montelukast

Ongoing
4
30
Europe
singulair junior 5 mg, SINGULAIR junior° 5 mg, SINGULAIR junior° 5 mg
Research Institute for the prevention of allergy and airway diseases in childhood
asthma bronchiale in childhood
 
 
2006-000334-12: A RANDOMIZED, PLACEBO CONTROLLED, DOUBLE-BLIND, CROSS-OVER, MONOCENTER STUDY TO EVALUATE THE EFFECT OF A 7-DAY MONTELUKAST TREATMENT ON AIRWAY INFLAMMATION AND FUNCTION BY MEANS OF BRONCHOPROVOCATION WITH ADENOSINE-5’-MONOPHOSPHATE IN PATIENTS WITH MILD OR MODERATE ALLERGIC ASTHMA

Ongoing
4
18
Europe
Montelukast, Montelukast capsule,
Almirall Prodesfarma
Mild to moderate asthma according to GINA (Global initiative for Asthma, 2004) guidelines.
 
 
2008-000511-16: Management of Asthma in School age Children On Therapy

Ongoing
4
450
Europe
Flixotide Accuhaler, Seretide Accuhaler, Singulair, Flixotide Accuhaler, Seretide Accuhaler, Singulair
Keele University, University Hospital of North Staffordshire NHS Trust
Chronic asthma (paediatric population)
 
 
2011-003652-39: Exercise induced bronchoconstriction in children – a single dose of montelukast as alternative to regular daily doses. Anstrengelsesudløst astma hos børn – enkeltdosering af montelukast som alternativ til fast daglig dosering.

Ongoing
4
32
Europe
Singulair, Singulair
Karen Schow Jensen, Forskningspuljen Hillerød Hospital, Kaptajnløjtnant Harald Jensens og hustrus Fond, Aase og Ejnar Danielsens Fond, Direktør Jacob Madsen & Hustru Olga Madsens Fond, Carl og Ellen Hertz’ legat til Dansk Læge- og Naturvidenskab, Dagmar Marshalls Fond
Exercise induced asthma
 
 
ChiCTR-IPR-16008163: The individualized treatment depended on combination the key nasal clinical manifestations with experimental detecting for histamine and leukotriene D4 in allergic rhinitis

Completed
4
120
 
Patients are treated with loratadine and montelukast or topical nasal steroids in 4 weeks.
Department of Otorhinolaryngology-Head and Neck Surgery, Zhujiang Hospital, Southern Medical University; Zhujiang Hospital, Scientific research project in 2013
Allergic Rhinitis
 
 
ChiCTR-TRC-14004375: Comparison of daily mometasone furoate nasal spray alone versus a combination with montelukast for treatment of chronic rhinosinusitis with asthma after functional endoscopic sinus surgery: a 9-month randomized, open-label, controlled study

Recruiting
4
60
 
Montelukast (10mg, once daily) for 6 months ;mometasone furoate nasal spray (200ug, once daily) for 6 months
The First Affiliated Hospital, Sun Yat-sen University; Level of the institution：, Industry Foundation of the Ministry of Health, China (201202005),
chronic rhinisinusitis with asthma
 
 
2016-003061-25: Brain activity changes under treatment with Montelukast.

Ongoing
4
24
Europe
Singulair, Coated tablet, Singulair
Department of Neurology, Christian Doppler Medical Center, Paracelsus Medical University Salzburg, Paracelsus Medical University Salzburg
Montelukast is indicated for prophylaxis and chronic treatment of asthma and for the relief of symptoms of seasonal allergic rhinitis.We investigate side effects of Montelukast, specifically potential effects on brain activity., Montelukast is used for treatment of asthma and allergic rhinitis. We examine the effect of Montelukast on brain activity., Diseases [C] - Respiratory Tract Diseases [C08]
 
 
2015-001736-38: The utility of feNO in the differential diagnosis of chronic cough

Not yet recruiting
4
60
Europe
Montelukast, Prednisolone, Film-coated tablet, Tablet, Montelukast, Prednisolone
Hull and East Yorkshire Hospitals NHS trust, Aerocrine Limited
Chronic cough is a common and poorly diagnosed condition. Younger patients tend to receive a diagnosis of asthma, whereas older patients are increasingly identified has having gastroesophageal reflux disease. Those patients presenting with upper airway symptoms are frequently labelled as having rhinitis. A considerable proportion of patients elude a diagnosis, either through testing or by the use of therapeutic trials and are then labelled as idiopathic cough., Chronic cough is a common and poorly diagnosed condition. There are different causes of chronic cough the most common causes are asthma, postnasal drip and gastro-oesophageal reflux., Diseases [C] - Respiratory Tract Diseases [C08]
 
 
ChiCTR-IIR-17012223: A Randomized, Open-labeled, Parallel Controlled Study on the Efficacy and Safety of Combined Medication with Procaterol Hydrochloride and Montelukast in Treatment of Cough variant Asthma in Children.

Completed
4
490
 
Procaterol Hydrochloride and Montelukast ;Montelukast
Beijing Children’s Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, Zhejiang Otsuka Pharmaceutical Co., Ltd
Cough variant Asthma
 
 
rhinitis, NCT06806826: The Effect of Omalizumab on Allergic Rhinitis Symptoms: a Comparative Study

Completed
4
50
RoW
Omalizumab, desloratadin + montelukast
Yuzuncu Yıl University
Allergic Rhinitis
01/20
03/20
2020-001747-21: Efficacy and safety of Montelukast as add on treatment to the novel coronavirus pneumonia (COVID-19)

Ongoing
4
160
Europe
Film-coated tablet, Montelucaste Generis
Instituto de Saúde Pública Universidade Porto, Instituto de Saúde Pública Universidade Porto, Centro Hospitalar Universitário de São João
Novel coronavirus pneumonia (COVID-19), Novel coronavirus pneumonia (COVID-19), Diseases [C] - Virus Diseases [C02]
 
 
NCT04957927: Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age

Recruiting
4
60
RoW
Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age
Usama Azhar, King Edward Medical University
Allergic Rhinitis
09/21
12/21
NCT05094596: Effect of Montelukast Therapy on Clinical Course, Pulmonary Function, and Mortality in Patients With COVID-19

Not yet recruiting
4
180
RoW
Standart treatment group, Montelukast sodium 10 mg treatment, Montelukast sodium 20 mg treatment
Bugra Kerget
COVID-19 Pneumonia
12/21
01/22
ChiCTR2000030676: A prospective randomized controlled clinical study of Montelukast in the treatment of postoperative lymphedema of breast cancer

Recruiting
4
80
 
complete decongestive therapy ;complete decongestive therapy combined with Montelukast
The Fifth Affiliated Hospital of Sun Yat-Sen University; The Fifth Affiliated Hospital of Sun Yat-Sen University, None
lymphedema
 
 
NCT04815187: Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's Disease

Active, not recruiting
4
39
US
Montelukast, Placebo
House Ear Institute, Cures Within Reach
Meniere Disease, Allergic Rhinitis, Vertigo
09/25
12/25
NCT04953741: A Comparative Study on the Efficacy of Different Stepping-down Therapy for Childhood Asthma

Not yet recruiting
4
90
RoW
Fluticasone propionate inhaled aerosol
Xijing Hospital
Asthma in Children
08/22
08/22
NCT05651750: Medical vs Surgical Treatment in OSA Among Children

Recruiting
4
90
RoW
Montelukast, Singulair, Fluticasone Furoate, Avamys
Assaf-Harofeh Medical Center
To Evaluate PSQ as Clinical Tool in the Decision Between Medical and Surgical Treatment for Adenotonsillar Hypertrophy, To Determine Clinical Response to Montelukast or Nasal Steroids Based on PSQ Results
05/23
06/23
AMBT, NCT04527016: Airway Microbiota Based Treatment of Asthma in Preschool Children

Completed
4
120
RoW
Microbiota and eosinophils based therapy, Clinical guidelines based therapy
Children's Hospital of Fudan University
Asthma in Children
06/23
06/24
NCT04613180: Evaluation of the Effectiveness of Montelukast in Children With Recurrent Obstructive Bronchitis

Active, not recruiting
4
100
RoW
Montelukast Sodium, Singulair, Placebo
Samarkand State Medical Institute
Acute Bronchiolitis
12/23
06/24
NCT04762472: Air Pollution (PM2.5) on Accelerated Atherosclerosis: A Montelukast Interventional Study in Modernizing China

Not yet recruiting
4
200
RoW
Montelukast Oral Tablet, Montelukast (active), Montelukast Placebo Oral Tablet, Montelukast Placebo (control)
Chinese University of Hong Kong, People's Hospital of Chongqing, Hong Kong University of Science and Technology, Chongqing Medical University, University of Sydney
Atherosclerosis, Coronary
12/24
12/25
SHORTEN, NCT06019728: A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazyme

Completed
4
8
US
AGALSIDASE BETA (GZ419828), Fabrazyme, Acetaminophen, Diphenhydramine, Dexamethasone, Montelukast, Loratadine, Cetirizine, Fexofenadine
Sanofi
Fabry's Disease
10/24
10/24
NCT05498116: Effect of Montelukast on Kidney and Vascular Function in Type 1 Diabetes

Recruiting
4
50
US
Montelukast, Placebo
University of Colorado, Denver
Albuminuria
10/25
10/25
ACTRN12605000397617: Towards better assessment and treatment of exercise induced wheeze

Not yet recruiting
3
60
 
University of Otago, Lottery Grants Board NZ, Asthma and Respiratory Foundation of NZ
Exercise induced wheeze, Asthma
 
 
2008-006437-26: Effect of montelukast on lung function in children younger than 2 years with wheezing.

Ongoing
3
40
Europe
Chewable tablet
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
Recurrent wheezing
 
 
2021-000605-24: Study to assess the efficacy of montelukast in improving respiratory symptoms in patients with long COVID: E-SPERANZA COVID PROJECT Estudio para valorar la eficàcia del montelukast en la mejoría de los síntomas respiratorios en pacientes con COVID persistente: PROYECTO E-SPERANZA COVID

Ongoing
3
284
Europe
Capsule
IDIAP Jordi Gol, Universitat Autònoma de Barcelona (UAB), IDIAP Jordi Gol
Patients with a history of SAR-Cov-2 infection (PCR positive) with long Covid-19 and mild or moderate respiratory symptoms of more than 1 month and less than 4 months of evolution, attended in Primary Care. Pacientes con antecedentes de infección por SAR-Cov-2 (PCR positivo) con Covid-19 persistente y síntomas respiratorios leves o moderados de mas de 1 mes y menos de 4 meses de evolución, atendidos en Atención Primaria., Patients attended in Primary Care with persistent Covid in which mild or moderate respiratory symptoms last more than 1 month and less than 4 months. Pacientes atendidos en Atención Primaria con Covid persistente en los cuales los síntomas respiratorios leves o moderados duran mas de 1 mes y menos de 4 meses., Diseases [C] - Virus Diseases [C02]
 
 
2021-001465-20: Clinical trial to assess the efficacy and safety of Montelukast in patients with erosive / inflammatory arthrosis of the hands Ensayo clínico para evaluar la eficacia y seguridad de Montelukast en pacientes con artrosis erosiva/inflamatoria de manos

Not yet recruiting
3
280
Europe
Montelukast sodium, Capsule, hard
Laboratorios Farmalíder S.A., Laboratorios Farmalíder S.A.
Erosive / inflammatory arthrosis of the hands Artrosis erosiva/inflamatoria de manos, Erosive / inflammatory arthrosis of the hands Artrosis erosiva/inflamatoria de manos, Diseases [C] - Musculoskeletal Diseases [C05]
 
 
ESPERANZACOVID, NCT04695704: Efficacy of Montelukast in Mild-moderate Respiratory Symptoms in Patients With Long-COVID-19:

Terminated
3
86
Europe
Montelukast, antileukotriene, placebo
Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina, Institut Català de la Salut
Covid19, SARS (Disease)
07/23
08/23
NCT05894577: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast)

Completed
3
1453
US
Placebo, Montelukast
Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center
Covid19
07/23
01/24
CADET-PAD, NCT04277702 / 2020-000715-71: Cysteinyl Leukotriene Antagonist in Atherosclerosis Inhibition in Patients After Endovascular Treatment Due to Peripheral Arterial Disease

Not yet recruiting
3
200
NA
Montelukast 10mg, Endovascular treatment, Standard anti-platelet treatment
Jagiellonian University, National Science Centre
Peripheral Arterial Disease, Peripheral Vascular Diseases, Lower Limb Ischemia, Atherosclerosis of Artery
10/23
12/23
NCT05325489: Comparison of Nebulized Budesonide and Intranasal Budesonide Spray in Children With Adenotonsillar Hypertrophy

Not yet recruiting
3
100
RoW
Nebulized Budesonide, Intranasal Budesonide Spray
Second Xiangya Hospital of Central South University
Snoring, Mouth Breathing
11/23
09/24
NCT02793375: Does Montelukast Decrease Post Adenotonsillectomy Pain in Children

Completed
3
117
US
Montelukast, Placebo
Children's Hospital Medical Center, Cincinnati
Pain
11/24
11/24
NCT04885530: ACTIV-6: COVID-19 Study of Repurposed Medications

Completed
3
10956
US
Ivermectin, Ivermectin Tablets, Fluvoxamine, Fluvoxamine Maleate Tablets, Fluticasone, Fluticasone Furoate, Placebo, Montelukast, Metformin
Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center
Covid19
04/24
04/24
NCT05362474: Targeting Leukotrienes in Kidney Disease

Terminated
3
5
US
Montelukast
University of Colorado, Denver
Diabetic Kidney Disease
06/23
06/23
IRAKLIA, NCT05405166 / 2021-002485-41: SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM

Active, not recruiting
3
531
Europe, Canada, Japan, US, RoW
Isatuximab IV, SAR650984, SARCLISA®, Isatuximab SC, Dexamethasone, Pomalidomide, Pomalyst or equivalent, Montelukast, Paracetamol / Acetaminophen, Diphenhydramine, Methylprednisolone
Sanofi, Sanofi-aventis recherche & developpement
Plasma Cell Myeloma Recurrent
11/24
03/27
NCT06340984: Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast

Not yet recruiting
3
60
NA
Montelukast 10 Mg Oral Tablet, level of serum intercellular adhesion molecule -1 will be measured by performing an enzyme-linked immune sorbent assay (E LISA)
South Valley University
Acne Vulgaris
11/24
02/25
AIRSA001, NCT06429475: Anti-Inflammatory Reliever South Africa

Enrolling by invitation
3
1038
RoW
Budesonide/formoterol, No other intervention names, standard of care, beclomethasone or budesonide & salbutamol or mentelukast
University of KwaZulu
Asthma
05/25
05/26
NCT03770923: Effect of Some Drugs on Rheumatoid Arithritis Activity

Recruiting
3
75
RoW
Rupatadine, Montelukast
Sherief Abd-Elsalam
Rheumatoid Arthritis
10/26
10/27
ITHACA, NCT04270409 / 2019-003139-47: Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma

Active, not recruiting
3
337
Europe, Canada, Japan, US, RoW
Isatuximab SAR650984, Sarclisa, Lenalidomide, Dexamethasone, Montelukast or equivalent, Acetaminophen, Diphenhydramine or equivalent, Methylprednisolone or equivalent
Sanofi
Plasma Cell Myeloma
10/30
10/33
ACTRN12617001516370: MOM trial. MOntelukast Myeloma A pilot study to determine whether Montelukast added to standard Chemotherapy improves response in patients who have failed standard Chemotherapy for Multiple Myeloma.

Active, not recruiting
2/3
6
 
Dr Stephen Kenneth O'Mara, Dr Stephen O'Mara
Multiple Myeloma
 
 
2017-004539-36: Study of Montelukast In Children with Sickle Cell Disease

Ongoing
2/3
200
Europe
Montelukast, N/A, Chewable tablet, Montelukast
Great Ormond Street Hospital for Children NHS Foundation Trust
Sleep-disordered breathing, Obstructive Sleep Apnoea, Psychiatry and Psychology [F] - Psychological processes [F02]
 
 
COSMO, NCT04389411: The Covid-19 Outpatient Symptom Montelukast Oximetry Trial

Not yet recruiting
2/3
250
NA
Montelukast 10mg
McGill University, Segal Cancer Centre, The McGill Practice Based Research Network, Lady Davis Institute
COVID-19
01/23
02/25
NCT05293132: Effect of Montelukast Versus Co Enzyme in Sepsis

Completed
2/3
90
RoW
Montelukast Sodium 10 mg, (Singulair®; Merck & Co Inc) or (Clear air®; Amoun Pharmaceutical Company S.A.E., Egypt), Co-Enzyme Q10, Co enzyme Q10(MEPACO Pharmaceutical Company (Egypt), Standard Treatment, Standard sepsis treatment
Ain Shams University
Sepsis
06/23
06/23
NCT04673422: Effect of Montelukast in Preventing Dengue With Warning Signs in Dengue Patients

Completed
2/3
358
RoW
Montelukast, Placebo
Phramongkutklao College of Medicine and Hospital
Dengue, Dengue With Warning Signs, Dengue Shock Syndrome
06/23
06/23
SMILES, NCT04351698: Study of Montelukast in Sickle Cell Disease

Recruiting
2/3
200
Europe
Montelukast, singulair, Oral Placebo
Great Ormond Street Hospital for Children NHS Foundation Trust, Guy's and St Thomas' NHS Foundation Trust, University College London Hospitals, North Middlesex University Hospital, King's College Hospital NHS Trust, The Whittington Hospital NHS Trust
Anemia, Sickle Cell, Sleep-Disordered Breathing
09/24
09/24
NCT06113640: Montelukast in Parkinson Disease

Recruiting
2/3
60
RoW
levodopa-carbidopa, Montelukast
Mostafa Bahaa
Parkinson Disease
11/24
12/25
NCT06747130: Efficacy of Montelukast in Preventing Transaminase Elevation in Adult Dengue Patients

Not yet recruiting
2/3
82
NA
Montelukast, Montelukast Placebo
Phramongkutklao College of Medicine and Hospital
Dengue, Montelukast, Transaminases
01/27
01/27
ChiCTR-IPR-15006578: The efficacy and safety evaluation of Xiao'er Kechuan Granule in children’s Cough Variant Asthma with syndrome of wind invading lung: a randomized, double-blind, double-dummy, parallel, active-controlled, Dose exploration,multi-center clinical trial

Recruiting
2
96
 
Take Xiao'er Kechuan Granule 2 bags,Tid; montelukast (Singulair) placebo,1 pill ,Qn p.o ;Take Xiao'er Kechuan Granule 1 bag and Xiao'er Kechuan Granule placebo 1 bag,Tid; montelukast (Singulair) placebo,1 pill ,Qn p.o ;Take Xiao'er Kechuan Granule placebo 2 bags,Tid; montelukast (Singulair) placebo,1 pill ,Qn p.o ;Take Xiao'er Kechuan Granule 2 bags,Tid; montelukast (Singulair),1 pill ,Qn p.o
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; Level of the institution：, Beijing Sihuan Kebao Pharmaceutical Co., Ltd.
Cough Variant Asthma
 
 
NCT04551755: Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19

Not yet recruiting
2
188
NA
Ivermectin and Doxycycline, Placebo
Bangladesh Medical Research Council (BMRC)
Covid19
11/20
12/20
2020-000715-71: The assessment of cysteinyl leuktriene receptor antagonist (montelukast) role in inhibition of atherosclerosis in patients undergoing endovascular treatment due to peripheral arterial disease. Ocena wpływu zastosowania antagonisty receptora leukotrienowego (montelukast) na zahamowanie rozwoju miażdżycy zarostowej tętnic u pacjentów leczonych wewnątrznaczyniowo z powodu niedokrwienia kończyn dolnych

Not yet recruiting
2
200
Europe
Tablet, Asmenol
Jagiellonian University Medical College, National Science Centre
Occlusive atherosclerosis in patients treated endovascularly due to ischemia of the lower limbs in the course of obstructive artery disease. Miażdżyca zarostowa tętnic u pacjentów leczonych wewnątrznaczyniowo z powodu niedokrwienia kończyn dolnych w przebiegu miażdżycy zarostowej tętnic., Ischemia of the lower limbs in the course of obstructive artery disease Niedokrwienie kończyn dolnych w przebiegu miażdżycy tętnic kończyn dolnych., Diseases [C] - Cardiovascular Diseases [C14]
 
 
2020-000148-76: Effects of the Montelukast drug on brain inflammation in Parkinson's disease.

Not yet recruiting
2
15
Europe
Montelukast Krka, Film-coated tablet, Montelukast
Stockholm Health Care Services, Axel och Margaret Ax:son Johnson’s foundation
Parkinson's disease, Parkinson's disease, Diseases [C] - Nervous System Diseases [C10]
 
 
ChiCTR2000039630: Phase II clinical trial of the superiority of montelukastine in combination with TPO-MPL agonists for the treament of primary immune thrombocytopenia

Recruiting
2
102
 
Montelukast sodium 10mg/day; rhTPO 15000 units ;rhTPO 15000 units
Department of Hematology, Second Medical Center, Chinese PLA General Hospital; Chinese PLA General Hospital, Hospital research projects
Primary immune thrombocytopenia
 
 
NCT04718285: Investigation the Effect of Montelukast in COVID-19

Recruiting
2
380
RoW
Montelukast Oral Tablet, Montelukast plus Favicovir (Favipiravir), Favicovir (Standard Treatment)
Bahçeşehir University, Medipol University, The Scientific and Technological Research Council of Turkey
COVID-19, SARS-CoV-2
05/22
06/22
ISAKIDS, NCT03860844 / 2018-002697-45: Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Hourglass Jan 2022 - Dec 2022 : From trial in pediatrics with r/r AML/ALL
Terminated
2
67
Europe, US, RoW
Isatuximab, SAR650984, Sarclisa, Dexamethasone or equivalent, Fludarabine, Cytarabine, Liposomal daunorubicin, Daunorubicin (nonliposomal), Idarubicin, Filgrastim or equivalent, Mitoxantrone, Doxorubicin, Vincristine, Pegaspargase (PEG) Asparaginase, Cyclophosphamide, Etoposide, Methotrexate, L - Asparginase, Hydroxyurea, L - Asparaginase (Erwinase)
Sanofi
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
09/22
05/23
NCT05447520: Montelukast Use in Rheumatoid Arthritis

Completed
2
92
RoW
Montelukast, Placebo, Conventional DMARDs
Noha Mansour
Rheumatoid Arthritis
12/22
12/22
2022-000974-25: Evaluation of Amivantamab Infusion Related Reaction Mitigation Evaluación de la Mitigación de las Reacciones Relacionadas con la Infusión de Amivantamab.

Not yet recruiting
2
120
Europe
Lazertinib mesylate monohydrate, Amivantamab, Dexamethasone, Montelukast Sodium, Methotrexate, JNJ-73841937-ZCY/YH25448AM, JNJ-61186372, Film-coated tablet, Concentrate for solution for infusion, Tablet, Injection, Dexamethasone, Montelukast Sodium, Methotrexate
Janssen-Cilag International NV, Janssen Research & Development, LLC
EGFR-mutated Advanced or Metastatic Non-small Cell Lung Cancer Mutación del EGFR en Cáncer de Pulmón No Microcítico avanzado o metastásico, A specific type of lung cancer called "Non-Small Cell Lung Cancer Tipo específico de Cáncer de Pulmón llamado "Cáncer de Pulmón No Microcítico", Diseases [C] - Cancer [C04]
 
 
2020-005135-73: A clinical trial to evaluate the safety and the efficacy of a combination of Rupatadine and Montelukast compared to Rupatadine in patients with allergic rhinitis Un ensayo clínico para evaluar la seguridad y la eficacia de la combinación de rupatadina y montelukast en comparación con solo rupatadina en pacientes con rinitis alérgica

Not yet recruiting
2
300
Europe, RoW
Rupatadine, Montelukast, Tablet, Rupatadina Uriach 10 mg comprimidos EFG, SINGULAIR 10 mg COMPRIMIDOS RECUBIERTOS CON PELICULA
Biohorm S.L, Biohorm, S.L., Biohorm S.L, Biohorm, S.L.
Seasonal allergic rhinitis with and without mild to moderate bronchial asthma Rinitis alérgica estacional con y sin asma bronquial leve a moderada, Seasonal alergic rhinitis with or without asthma Rinitis alérgica estacional con y sin asma, Diseases [C] - Immune System Diseases [C20]
 
 
NCT04198623: Efficacy of Montelukast in Reducing the Incidence and Severity of Monoclonal Antibodies Associated Infusion Reactions

Completed
2
40
US
Montelukast 10 Mg Oral Tablet, Singulair
University of California, San Francisco
Infusion Reaction, Monoclonal Antibody
07/24
07/24
NCT05704049: A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Active, not recruiting
2
74
Europe, Japan, RoW
Isatuximab, Carfilzomib, Kyprolis, Dexamethasone, Dexamethasone IV, Montelukast, Acetaminophen, Diphenhydramine, Methylprednisolone
Sanofi
Relapsed/Refractory Multiple Myeloma
11/24
03/27
SKIPPirr, NCT05663866: Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Active, not recruiting
2
73
Europe, US, RoW
Dexamethasone, Montelukast, Methotrexate, Amivantamab, JNJ-61186372, Lazertinib, JNJ-73841937
Janssen Research & Development, LLC
Carcinoma, Non-Small-Cell Lung
03/24
10/25
NCT05922761: BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

Recruiting
2
45
US
Belumosudil, Rezurock, KD025, 2-{3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy}-N-(propan-2-yl) acetamide, C26H24N6O2, Fluticasone, Fluticasone Propionate, Azithromycin, Zithromax, Prednisone, Montelukast, Singulair
Dana-Farber Cancer Institute, Sanofi, National Heart, Lung, and Blood Institute (NHLBI)
Bronchiolitis Obliterans Syndrome, Bronchiolitis Obliterans, Lung Diseases, Chronic Graft Versus Host Disease
06/26
12/26
SubQSA, NCT06356571: A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Recruiting
2
64
US
Isatuximab SC-OBDS, SAR650984, Sarclisa, Montelukast, Dexamethasone, Acetaminophen, Diphenhydramine, Methylprednisolone, Carfilzomib
Sanofi
Plasma Cell Myeloma Refractory
01/27
07/27
NCT05807048: Daratumumab in STK11 Mutated NSCLC

Recruiting
2
14
US
Daratumumab and Hyaluronidase-fihj, DARZALEX FASPRO, Pre-Intervention Medication, Post-Intervention Medication
NYU Langone Health
Non-small Cell Lung Cancer With STK11/LKB1 Mutation
05/26
12/26
TEAM, NCT05819541: Treating Exacerbations of Asthma With Oral Montelukast in Children

Recruiting
2
90
US
Montelukast Oral Granules, Singulair, Albuterol, Inhaled albuterol, Corticosteroid, Systemic corticosteroid
Vanderbilt University Medical Center
Status Asthmaticus
06/25
10/25
FLASH, NCT05251259 / 2021-003338-35: Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-Severe Uncontrolled Asthma

Recruiting
2
666
Europe, Japan, US, RoW
Atuliflapon, AZD5718, Placebo
AstraZeneca, AstraZeneca AB
Asthma
01/26
01/26
NCT04268498: A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma

Recruiting
2
306
Europe, US
Bortezomib, Dexamethasone, Lenalidomide, Revlimid, Acetaminophen, Diphenhydramine, Montelukast, Carfilzomib, Daratumumab, Autologous Stem Cell Transplant (ASCT)
University of Miami, Amgen, Janssen Pharmaceuticals
Multiple Myeloma
02/27
02/27
NCT03277170: Pragmatic RCT of High-dose Oral Montelukast for Moderate and Severe Pediatric Acute Asthma Exacerbations

Withdrawn
2
320
US
Montelukast Oral Granules, Singulair
Vanderbilt University Medical Center
Asthma; Status, Asthma in Children, Asthma Acute, Asthma Attack, Acute Asthma Exacerbation
08/28
09/29
Iber-KDd, NCT05896228: Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone () in Patients with Relapsed/Refractory Multiple Myeloma

Recruiting
2
30
US
Iberdomide, Carfilzomib, Daratumumab, Dexamethasone, Acetaminophen, Diphenhydramine, Montelukast
Benjamin T Diamond, MD, Bristol-Myers Squibb
Refractory Multiple Myeloma, Relapsed Multiple Myeloma
03/29
03/31
NCT05143502: Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.

Active, not recruiting
1/2
60
RoW
Montelukast, Prednisolone, Fluticasone Furoate
Assiut University
Montelukast, Chronic Rhinosinusitis With Nasal Polyps
01/24
03/24
ACTRN12618001112257: A long term follow up study of ATX-101 given by intravenous infusion once every week in patients with advanced solid tumours.

Recruiting
1
36
 
Therapim Pty Ltd, Therapim Pty Ltd
Advanced Solid Tumors
 
 
EQUULEUS, NCT01998971: A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma

Checkmark The positive opinion of the CHMP on split dosing regimen for Darzalex
Nov 2018 - Nov 2018: The positive opinion of the CHMP on split dosing regimen for Darzalex
Checkmark Filed for a split dosing regimen
Aug 2018 - Aug 2018: Filed for a split dosing regimen
Checkmark Filed for Type II Variation of a split dosing regimen
More
Completed
1
240
Europe, US
Daratumumab, Velcade, Pomalidomide, Dexamethasone, Melphalan, Prednisone, Thalidomide, Diphenhydramine, Acetaminophen, Carfilzomib, Lenalidomide, Montelukast
Janssen Research & Development, LLC
Multiple Myeloma
01/19
01/24
ChiCTR2300075040: Effect of preoperative application of antiallergic drugs on adenoid pathology and postoperative recovery

Completed
1
20
 
Administration of the anti-allergy drug montelukast sodium ;Placebo control
Dalian municipal Central Hospital; Dalian municipal Central Hospital, Postgraduate research funding
Adenoid hypertrophy
 
 
NCT04075110: Investigation the Safety and Efficacy of The Antileukotriene Agents, Montelukast, as Adjuvant Therapy in Obese Patients With Type 2 Diabetes Mellitus

Completed
1
100
RoW
Montelukast 10mg, Placebo
Sadat City University
Obesity; Endocrine; Diabetes Type 2
06/22
04/23
NCT05852769: A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Completed
1
18
US
BMS-986196, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, Pravastatin
Bristol-Myers Squibb
Healthy Volunteers
08/23
08/23
NCT05607446: To Evaluate the Efficacy and Safety of TQC3564 Tablets in the Treatment of Persistent Allergic Rhinitis

Terminated
1
12
RoW
TQC3564 tablets, Placebo tablets, TQC3564 tablets, montelukast sodium tablets, Placebo tablets, montelukast sodium tablets
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Allergic Rhinitis
05/23
12/23
MOCHA, NCT04572256: MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction ( Trial)

Recruiting
1
30
US
Montelukast, Singulair, Placebo
Austin V Stone, Duke University, The Cleveland Clinic, University of California, San Francisco
ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
04/25
04/25
NCT05381207: Impact Of Montelukast On Allergic Rhinitis And Its Inflammatory Makers

Not yet recruiting
1
60
NA
Montelukast Oral Tablet, Fluticasone Furoate nasal spary
Assiut University
Allergic Rhinitis
10/24
10/24
Clinical and basic research on adenoid hypertrophy in children, ChiCTR2400083549: Clinical and Basic Research on Yinbei Granules in the Treatment of Children with Adenoid Hypertrophy and Phlegm Accumulation Syndrome

Recruiting
1
100
 
Honeysuckle 9g, Fritillaria thunbergii 9g, Forsythia suspensa 9g, oyster 15g, burdock 9g, magnolia 6g, mint 6g, Atractylodes macrocephala 9g, Astragalus membranaceus 9g. Usage: The above traditional Chinese medicine granules are provided by Sichuan New Green Pharmaceutical Company< 1/2 dose per day for 3-year-old individuals and 1 dose per day for 3-6-year-old individuals. Rinse with warm water and take in separate doses in the morning and evening. Each course lasts for 4 weeks, with a total of 3 courses.; Oral administration of Montelukast sodium tablets: 3+~6 years old, 4mg each time, once every night; 6+to 14 years old, 5mg per dose, once per night. Pingqi (Menglujite Sodium Tablets), Lunanbeite Pharmaceutical Co., Ltd., Product Approval Number: National Pharmaceutical Approval Letter H20083372. Each course lasts for 4 weeks, with a total of 3 courses.
Shanghai Municipal Hospital of Traditional Chinese Medicine; Shanghai Municipal Hospital of Traditional Chinese Medicine, Task Book for the Construction of the Three Year Action Plan for Further Accelerating the Inheritance, Innovation and Development of Traditional Chinese Medicine in Shanghai - ZY (2021-2023) -0209-05
adenoidal hypertrophy
 
 
NCT06887673: Lipid Mediators & Cancer: Montelukast, SPM, and Almonds

Not yet recruiting
1
56
US
No Interventions, Sports Pro Resolve 4 g, Double Wood SPM 4 g, 20 California Sweet Almonds, Montelukast 10 Mg Oral Tablet, Montelukast 10 Mg Oral Tablet and SPM 4 g, Cold- Pressed Almond Oil 30 mL
University of South Florida
Colorectal Cancer, Sarcoma, Brain Tumors, Endometrial Cancer, Ovarian Cancer
03/26
03/26
(GWI), NCT05992311: Clinical Evaluation of Montelukast in Veterans with Gulf War Illness

Not yet recruiting
1
80
US
Montelukast, Singulair, Placebo
Baylor College of Medicine, Michael E. DeBakey VA Medical Center, Texas A&M University
Gulf War Syndrome
04/28
08/28
ChiCTR-TRC-09000688: Receptor Antagonist in the Treatment of Allergic Rhinitis

Completed
N/A
46
 
Montelukast 26 weeks per subject versus placebo
Prof. Albert Martin Li; Level of the institution：, MSD
asthma, allergic rhinitis
 
 
ChiCTR-OCC-13004324: The Effect of Jade Screen Powder on IgE and Eosinophils in Childhood Asthma of stable situation

Completed
N/A
500
 
Budesonide ;Montelukast ;Budesonide & JSP ;Montelukast & JSP ;JSP
Department of Pediatrics, Shanghai TCM-Integrated Hospital; Shanghai TCM-Integrated Hospital, TCM developing office of Shanghai health Bureau
childhood asthma
 
 
ChiCTR-OOC-15005841: Montelukast Sodium Tablets treatment clinical study for intractable cough by idiopathic pulmonary fibrosis

Recruiting
N/A
60
 
Montelukast Sodium Tablets: oral, 1 tablets each time (10mg), 1 time a day, at bedtime, for a period of 12 weeks ;Don't take Montelukast Sodium Tablets
Shanghai Pulmonary Hospital; None, no funding
Idiopathic pulmonary fibrosis
 
 
ChiCTR-INR-17010689: Clinical Study of Patients with Airway Hyperresponsiveness companied by Cough Variant Asthma

Completed
N/A
60
 
Allergy Decoction & Montelukast ;Montelukast
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University; Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Hospital-level Project Fund
CVA
 
 
LT and BPD, ChiCTR-ORN-16008890: Research on relationship of leukotrienes and bronchopulmonary dysplasia

Recruiting
N/A
200
 
therapy of Montelukast
First affiliated hospital of Nanjing Medical University; First affiliated hospital of Nanjing Medical University, self-financing
Bronchopulmanary dysplasia
 
 
ChiCTR-IOR-17012434: Clinical Observation of Chinese medicine acupoint sticking Combined with Montelukast in Treating Allergic Rhinitis in Children

Recruiting
N/A
180
 
Chinese medicine acupoint sticking Combined with Montelukast ;Chinese medicine acupoint sticking ;Montelukast
Shanghai Children's Medical Center Affiliated Shanghai Jiao Tong University; Shanghai Children's Medical Center, Shanghai Scinece and Technology Commission
allergic rhinitis
 
 
ChiCTR-IOR-17010765: Study on the curative evaluation of the Gufei Tang in the treatment of combined allergic rhinitis and asthma syndrome

Recruiting
N/A
106
 
Granule of Gufei Tang plus Montelukast Sodium Tablets ;Placebo granule of Gufei Tang plus Montelukast Sodium Tablets
Guangdong Provincial Hospital of Chinese Medicine; Guangdong Provincial Hospital of Chinese Medicine, Special subject construction of Guangdong high level University
Combined allergic rhinitis and asthma syndrome
 
 
NCT04561687: Comparison of Montelukast and Azelastine in Treatment of Moderate to Severe Allergic Rhinitis

Recruiting
N/A
66
RoW
Montelukast, Azelastine, Budesonide, Placebo
Shiraz University of Medical Sciences
Allergic Rhinitis
09/21
12/21
NCT04621513: Collaborative Care Model for Allergic Rhinitis With Obstructive Sleep Apnea From Prevention to Treatment.

Recruiting
N/A
60
RoW
laser acupuncture (RJ laser S/N 1813458), western medicine, intra-nasal corticosteroid(AVAMYS) with Montelukast (singulair)
China Medical University Hospital
Pediatric Sleep Apnea
12/21
12/22
ChiCTR2000032153: Clinical study on the treatment of chronic persistent stage of bronchial asthma with the method of Jieyu Sufei Decoction

Not yet recruiting
N/A
66
 
JieYuSuFei decoction ;Montelukast sodium tablets and/or Salmeterol ticasone powder inhaler
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine; Xiyuan Hospital, Chinese Academy of traditional Chinese Medicine, Xiyuan Hospital, Chinese Academy of traditional Chinese Medicine
Asthma
 
 
NCT04322422: Clinical Characteristics and Treatment of Chest Tightness Variant Asthma

Recruiting
N/A
300
RoW
Inhaled corticosteriod/long-acting beta-agonist plus Montelukast, Inhaled corticosteriod/long-acting beta-agonist only
Second Affiliated Hospital, School of Medicine, Zhejiang University
Asthma, Chest Syndrome, Clinical Anxiety, Clinical Depression, Lung Function, Quality of Life, Eosinophilia, Nitric Oxide, Airway Responsiveness, Induced Sputum
07/22
12/22
ChiCTR2100052064: The efficacy of sanjietongqiao prescription in the treatment of children with adenoid hypertrophy

Not yet recruiting
N/A
60
 
Sanjietongqiao prescription ;Montelukast Sodium (MS) combined with Mometasone Furoate Nasal Spray Nasal Spray (MFNSNS)
Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Shandong University of Chinese Medicine, Self-funded
adenoid hypertrophy
 
 
ChiCTR1900028522: Nasal eosinophilia in nasal smears of patients with chronic rhinitis

Recruiting
N/A
600
 
Budesonide nasal spray ;Budesonide nasal spray+montelukast ;Budesonide nasal spray +Loratadine
Jinhua Hospital of Zhejiang University; Jinhua Central Hospital, the Young and Middle-aged Research Startup Fund of Jinhua Central Hospital
chronic rhinitis
 
 
NCT05457855: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Montelukast vs Fluticasone

Active, not recruiting
N/A
75678
US
Montelukast, Fluticasone
Brigham and Women's Hospital, National Institute on Aging (NIA), Rutgers University, Johns Hopkins University
Asthma
07/23
12/23
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
montelukast / Generic mfg.
ChiCTR-TRC-07000028: Randomized controlled study of montelukast on patients with bronchiolitis

Completed
4
132
 
Regular treatment plus administration of montelukast for 7 days ;General regular treatment: anti-infection, oxygen uptake, cough suppression, sedation and inhalation therapy ofα2-receptor agonists ventolin ;Regular treatment and inhalation therapy of budesonide ;Regular treatment and inhalation therapy of Montelukast for 28 days
Postgraduate Department in the First Hospital Affiliated to Xinjiang Medical University; the First Hospital Affiliated to Xinjiang Medical University, Special fund for Evidence-Based Medicine in the First Hospital Affiliated to Xinjiang Medical College
Bronchiolitis
 
 
ChiCTR-TNRC-10000998: Impact of Smoking on Asthma and the Effect of Leukotriene Receptor Antagonist in asthma with smoking

Completed
4
37
 
Budesonide 200ug, inhalation, twice daily; salbutamol, inhalation, prn; Montelukast 10mg qn po. for 2 months ;Budesonide 200ug,inhalation, twice daily; salbutamol, inhalation, prn for 1month
Zhongshan Hospital, Fudan University; Level of the institution：, Zhongshan Hospital,Fudan University
asthma
 
 
ChiCTR-TRC-12002963: The Effcacy of Intranasal Budesonide and Leukotriene ModifierTherapy for Mild-moderate Pediatric Obstructive Sleep Apnean Hypopnea Syndrome

Completed
4
75
 
Montelukast Sodiuma 4mg or 5mg PO QN ;Rhinocort per puff per nostril to both nostrils b.i.d ;Rhinocort per puff per nostril to both nostrils b.i.d
The Fist Affiliated Hospital of Guangzhou Medical University; Level of the institution：, Principal Investigator Funds
Pediatric Obstructive Sleep Apnean Hypopnea Syndrome
 
 
ChiCTR-TRC-13003735: Add-on therapy with Montelukast in treatment of bronchiolitis

Completed
4
124
 
Add-on treatment with Montelukast ;Add-on treatment with Montelukast
Department of Pediatrics, The First Affiliated Hospital with Nanjing Medical University; The First Affiliated Hospital with Nanjing Medical University, Medical Emphasis Grant (No.56RC2002056) from Government of Jiangsu Province, China
bronchiolitis
 
 
ChiCTR-TRC-12002597: Clinical Study on the effects of add-on therapy with Montelukast in treatment of Henoch-Schnlein purpura

Completed
4
130
 
Routine treatment ;Routine treatment+Montelukast
Department of Pediatrics, First Affiliated Hospital of Nanjing Medical University; Department of Pediatrics, First Affiliated Hospital of Nanjing Medical University, Medical Emphasis Grant (No.56RC2002056) from Government of Jiangsu Province, China.
Henoch-Sch?nlein purpura(HSP)
 
 
2007-004541-15: A Randomized Controlled Open-Label Phase IV Mono Center Study to Compare the Reponse Profiles of Montelukast versus Fluticason in Children with Preschool Asthma

Ongoing
4
100
Europe
Singulair, Flutide, Singulair junior, Singulair mini 4mg Kautablette, Flutide mite 50 Dosier-Aerosol, Singulair junior 5mg Kautablette, Singulair mini 4mg Kautablette, Flutide mite 50 Dosier-Aerosol, Singulair junior 5mg Kautablette
Johann Wolfgang Goethe-Universität Frankfurt am Main
bronchial asthma is a very common medical problem in 3-7 year old children, often requiring hospitalization and demanding treatment on demand or permanently. Our trial is to compare to established treatment regimens with regard to their clinical efficacy
 
 
2005-001997-29: A Proof of Concept Study into the Effects on Inhlaed Extra-Fine and Standard Formulations of Beclomethasone Dipropionate and Oral Montelukast on Surrogate Markers of Small and Large Airway Inflammation in Asthma

Ongoing
4
30
Europe
Beclazone, QVAR, Singulair, Beclazone, QVAR, Singulair
University of Dundee
Asthma
 
 
2005-004115-29: Investigation to identify predictors of response to a treatment with montelukast

Ongoing
4
30
Europe
singulair junior 5 mg, SINGULAIR junior° 5 mg, SINGULAIR junior° 5 mg
Research Institute for the prevention of allergy and airway diseases in childhood
asthma bronchiale in childhood
 
 
2006-000334-12: A RANDOMIZED, PLACEBO CONTROLLED, DOUBLE-BLIND, CROSS-OVER, MONOCENTER STUDY TO EVALUATE THE EFFECT OF A 7-DAY MONTELUKAST TREATMENT ON AIRWAY INFLAMMATION AND FUNCTION BY MEANS OF BRONCHOPROVOCATION WITH ADENOSINE-5’-MONOPHOSPHATE IN PATIENTS WITH MILD OR MODERATE ALLERGIC ASTHMA

Ongoing
4
18
Europe
Montelukast, Montelukast capsule,
Almirall Prodesfarma
Mild to moderate asthma according to GINA (Global initiative for Asthma, 2004) guidelines.
 
 
2008-000511-16: Management of Asthma in School age Children On Therapy

Ongoing
4
450
Europe
Flixotide Accuhaler, Seretide Accuhaler, Singulair, Flixotide Accuhaler, Seretide Accuhaler, Singulair
Keele University, University Hospital of North Staffordshire NHS Trust
Chronic asthma (paediatric population)
 
 
2011-003652-39: Exercise induced bronchoconstriction in children – a single dose of montelukast as alternative to regular daily doses. Anstrengelsesudløst astma hos børn – enkeltdosering af montelukast som alternativ til fast daglig dosering.

Ongoing
4
32
Europe
Singulair, Singulair
Karen Schow Jensen, Forskningspuljen Hillerød Hospital, Kaptajnløjtnant Harald Jensens og hustrus Fond, Aase og Ejnar Danielsens Fond, Direktør Jacob Madsen & Hustru Olga Madsens Fond, Carl og Ellen Hertz’ legat til Dansk Læge- og Naturvidenskab, Dagmar Marshalls Fond
Exercise induced asthma
 
 
ChiCTR-IPR-16008163: The individualized treatment depended on combination the key nasal clinical manifestations with experimental detecting for histamine and leukotriene D4 in allergic rhinitis

Completed
4
120
 
Patients are treated with loratadine and montelukast or topical nasal steroids in 4 weeks.
Department of Otorhinolaryngology-Head and Neck Surgery, Zhujiang Hospital, Southern Medical University; Zhujiang Hospital, Scientific research project in 2013
Allergic Rhinitis
 
 
ChiCTR-TRC-14004375: Comparison of daily mometasone furoate nasal spray alone versus a combination with montelukast for treatment of chronic rhinosinusitis with asthma after functional endoscopic sinus surgery: a 9-month randomized, open-label, controlled study

Recruiting
4
60
 
Montelukast (10mg, once daily) for 6 months ;mometasone furoate nasal spray (200ug, once daily) for 6 months
The First Affiliated Hospital, Sun Yat-sen University; Level of the institution：, Industry Foundation of the Ministry of Health, China (201202005),
chronic rhinisinusitis with asthma
 
 
2016-003061-25: Brain activity changes under treatment with Montelukast.

Ongoing
4
24
Europe
Singulair, Coated tablet, Singulair
Department of Neurology, Christian Doppler Medical Center, Paracelsus Medical University Salzburg, Paracelsus Medical University Salzburg
Montelukast is indicated for prophylaxis and chronic treatment of asthma and for the relief of symptoms of seasonal allergic rhinitis.We investigate side effects of Montelukast, specifically potential effects on brain activity., Montelukast is used for treatment of asthma and allergic rhinitis. We examine the effect of Montelukast on brain activity., Diseases [C] - Respiratory Tract Diseases [C08]
 
 
2015-001736-38: The utility of feNO in the differential diagnosis of chronic cough

Not yet recruiting
4
60
Europe
Montelukast, Prednisolone, Film-coated tablet, Tablet, Montelukast, Prednisolone
Hull and East Yorkshire Hospitals NHS trust, Aerocrine Limited
Chronic cough is a common and poorly diagnosed condition. Younger patients tend to receive a diagnosis of asthma, whereas older patients are increasingly identified has having gastroesophageal reflux disease. Those patients presenting with upper airway symptoms are frequently labelled as having rhinitis. A considerable proportion of patients elude a diagnosis, either through testing or by the use of therapeutic trials and are then labelled as idiopathic cough., Chronic cough is a common and poorly diagnosed condition. There are different causes of chronic cough the most common causes are asthma, postnasal drip and gastro-oesophageal reflux., Diseases [C] - Respiratory Tract Diseases [C08]
 
 
ChiCTR-IIR-17012223: A Randomized, Open-labeled, Parallel Controlled Study on the Efficacy and Safety of Combined Medication with Procaterol Hydrochloride and Montelukast in Treatment of Cough variant Asthma in Children.

Completed
4
490
 
Procaterol Hydrochloride and Montelukast ;Montelukast
Beijing Children’s Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, Zhejiang Otsuka Pharmaceutical Co., Ltd
Cough variant Asthma
 
 
rhinitis, NCT06806826: The Effect of Omalizumab on Allergic Rhinitis Symptoms: a Comparative Study

Completed
4
50
RoW
Omalizumab, desloratadin + montelukast
Yuzuncu Yıl University
Allergic Rhinitis
01/20
03/20
2020-001747-21: Efficacy and safety of Montelukast as add on treatment to the novel coronavirus pneumonia (COVID-19)

Ongoing
4
160
Europe
Film-coated tablet, Montelucaste Generis
Instituto de Saúde Pública Universidade Porto, Instituto de Saúde Pública Universidade Porto, Centro Hospitalar Universitário de São João
Novel coronavirus pneumonia (COVID-19), Novel coronavirus pneumonia (COVID-19), Diseases [C] - Virus Diseases [C02]
 
 
NCT04957927: Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age

Recruiting
4
60
RoW
Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age
Usama Azhar, King Edward Medical University
Allergic Rhinitis
09/21
12/21
NCT05094596: Effect of Montelukast Therapy on Clinical Course, Pulmonary Function, and Mortality in Patients With COVID-19

Not yet recruiting
4
180
RoW
Standart treatment group, Montelukast sodium 10 mg treatment, Montelukast sodium 20 mg treatment
Bugra Kerget
COVID-19 Pneumonia
12/21
01/22
ChiCTR2000030676: A prospective randomized controlled clinical study of Montelukast in the treatment of postoperative lymphedema of breast cancer

Recruiting
4
80
 
complete decongestive therapy ;complete decongestive therapy combined with Montelukast
The Fifth Affiliated Hospital of Sun Yat-Sen University; The Fifth Affiliated Hospital of Sun Yat-Sen University, None
lymphedema
 
 
NCT04815187: Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's Disease

Active, not recruiting
4
39
US
Montelukast, Placebo
House Ear Institute, Cures Within Reach
Meniere Disease, Allergic Rhinitis, Vertigo
09/25
12/25
NCT04953741: A Comparative Study on the Efficacy of Different Stepping-down Therapy for Childhood Asthma

Not yet recruiting
4
90
RoW
Fluticasone propionate inhaled aerosol
Xijing Hospital
Asthma in Children
08/22
08/22
NCT05651750: Medical vs Surgical Treatment in OSA Among Children

Recruiting
4
90
RoW
Montelukast, Singulair, Fluticasone Furoate, Avamys
Assaf-Harofeh Medical Center
To Evaluate PSQ as Clinical Tool in the Decision Between Medical and Surgical Treatment for Adenotonsillar Hypertrophy, To Determine Clinical Response to Montelukast or Nasal Steroids Based on PSQ Results
05/23
06/23
AMBT, NCT04527016: Airway Microbiota Based Treatment of Asthma in Preschool Children

Completed
4
120
RoW
Microbiota and eosinophils based therapy, Clinical guidelines based therapy
Children's Hospital of Fudan University
Asthma in Children
06/23
06/24
NCT04613180: Evaluation of the Effectiveness of Montelukast in Children With Recurrent Obstructive Bronchitis

Active, not recruiting
4
100
RoW
Montelukast Sodium, Singulair, Placebo
Samarkand State Medical Institute
Acute Bronchiolitis
12/23
06/24
NCT04762472: Air Pollution (PM2.5) on Accelerated Atherosclerosis: A Montelukast Interventional Study in Modernizing China

Not yet recruiting
4
200
RoW
Montelukast Oral Tablet, Montelukast (active), Montelukast Placebo Oral Tablet, Montelukast Placebo (control)
Chinese University of Hong Kong, People's Hospital of Chongqing, Hong Kong University of Science and Technology, Chongqing Medical University, University of Sydney
Atherosclerosis, Coronary
12/24
12/25
SHORTEN, NCT06019728: A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazyme

Completed
4
8
US
AGALSIDASE BETA (GZ419828), Fabrazyme, Acetaminophen, Diphenhydramine, Dexamethasone, Montelukast, Loratadine, Cetirizine, Fexofenadine
Sanofi
Fabry's Disease
10/24
10/24
NCT05498116: Effect of Montelukast on Kidney and Vascular Function in Type 1 Diabetes

Recruiting
4
50
US
Montelukast, Placebo
University of Colorado, Denver
Albuminuria
10/25
10/25
ACTRN12605000397617: Towards better assessment and treatment of exercise induced wheeze

Not yet recruiting
3
60
 
University of Otago, Lottery Grants Board NZ, Asthma and Respiratory Foundation of NZ
Exercise induced wheeze, Asthma
 
 
2008-006437-26: Effect of montelukast on lung function in children younger than 2 years with wheezing.

Ongoing
3
40
Europe
Chewable tablet
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
Recurrent wheezing
 
 
2021-000605-24: Study to assess the efficacy of montelukast in improving respiratory symptoms in patients with long COVID: E-SPERANZA COVID PROJECT Estudio para valorar la eficàcia del montelukast en la mejoría de los síntomas respiratorios en pacientes con COVID persistente: PROYECTO E-SPERANZA COVID

Ongoing
3
284
Europe
Capsule
IDIAP Jordi Gol, Universitat Autònoma de Barcelona (UAB), IDIAP Jordi Gol
Patients with a history of SAR-Cov-2 infection (PCR positive) with long Covid-19 and mild or moderate respiratory symptoms of more than 1 month and less than 4 months of evolution, attended in Primary Care. Pacientes con antecedentes de infección por SAR-Cov-2 (PCR positivo) con Covid-19 persistente y síntomas respiratorios leves o moderados de mas de 1 mes y menos de 4 meses de evolución, atendidos en Atención Primaria., Patients attended in Primary Care with persistent Covid in which mild or moderate respiratory symptoms last more than 1 month and less than 4 months. Pacientes atendidos en Atención Primaria con Covid persistente en los cuales los síntomas respiratorios leves o moderados duran mas de 1 mes y menos de 4 meses., Diseases [C] - Virus Diseases [C02]
 
 
2021-001465-20: Clinical trial to assess the efficacy and safety of Montelukast in patients with erosive / inflammatory arthrosis of the hands Ensayo clínico para evaluar la eficacia y seguridad de Montelukast en pacientes con artrosis erosiva/inflamatoria de manos

Not yet recruiting
3
280
Europe
Montelukast sodium, Capsule, hard
Laboratorios Farmalíder S.A., Laboratorios Farmalíder S.A.
Erosive / inflammatory arthrosis of the hands Artrosis erosiva/inflamatoria de manos, Erosive / inflammatory arthrosis of the hands Artrosis erosiva/inflamatoria de manos, Diseases [C] - Musculoskeletal Diseases [C05]
 
 
ESPERANZACOVID, NCT04695704: Efficacy of Montelukast in Mild-moderate Respiratory Symptoms in Patients With Long-COVID-19:

Terminated
3
86
Europe
Montelukast, antileukotriene, placebo
Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina, Institut Català de la Salut
Covid19, SARS (Disease)
07/23
08/23
NCT05894577: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast)

Completed
3
1453
US
Placebo, Montelukast
Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center
Covid19
07/23
01/24
CADET-PAD, NCT04277702 / 2020-000715-71: Cysteinyl Leukotriene Antagonist in Atherosclerosis Inhibition in Patients After Endovascular Treatment Due to Peripheral Arterial Disease

Not yet recruiting
3
200
NA
Montelukast 10mg, Endovascular treatment, Standard anti-platelet treatment
Jagiellonian University, National Science Centre
Peripheral Arterial Disease, Peripheral Vascular Diseases, Lower Limb Ischemia, Atherosclerosis of Artery
10/23
12/23
NCT05325489: Comparison of Nebulized Budesonide and Intranasal Budesonide Spray in Children With Adenotonsillar Hypertrophy

Not yet recruiting
3
100
RoW
Nebulized Budesonide, Intranasal Budesonide Spray
Second Xiangya Hospital of Central South University
Snoring, Mouth Breathing
11/23
09/24
NCT02793375: Does Montelukast Decrease Post Adenotonsillectomy Pain in Children

Completed
3
117
US
Montelukast, Placebo
Children's Hospital Medical Center, Cincinnati
Pain
11/24
11/24
NCT04885530: ACTIV-6: COVID-19 Study of Repurposed Medications

Completed
3
10956
US
Ivermectin, Ivermectin Tablets, Fluvoxamine, Fluvoxamine Maleate Tablets, Fluticasone, Fluticasone Furoate, Placebo, Montelukast, Metformin
Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center
Covid19
04/24
04/24
NCT05362474: Targeting Leukotrienes in Kidney Disease

Terminated
3
5
US
Montelukast
University of Colorado, Denver
Diabetic Kidney Disease
06/23
06/23
IRAKLIA, NCT05405166 / 2021-002485-41: SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM

Active, not recruiting
3
531
Europe, Canada, Japan, US, RoW
Isatuximab IV, SAR650984, SARCLISA®, Isatuximab SC, Dexamethasone, Pomalidomide, Pomalyst or equivalent, Montelukast, Paracetamol / Acetaminophen, Diphenhydramine, Methylprednisolone
Sanofi, Sanofi-aventis recherche & developpement
Plasma Cell Myeloma Recurrent
11/24
03/27
NCT06340984: Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast

Not yet recruiting
3
60
NA
Montelukast 10 Mg Oral Tablet, level of serum intercellular adhesion molecule -1 will be measured by performing an enzyme-linked immune sorbent assay (E LISA)
South Valley University
Acne Vulgaris
11/24
02/25
AIRSA001, NCT06429475: Anti-Inflammatory Reliever South Africa

Enrolling by invitation
3
1038
RoW
Budesonide/formoterol, No other intervention names, standard of care, beclomethasone or budesonide & salbutamol or mentelukast
University of KwaZulu
Asthma
05/25
05/26
NCT03770923: Effect of Some Drugs on Rheumatoid Arithritis Activity

Recruiting
3
75
RoW
Rupatadine, Montelukast
Sherief Abd-Elsalam
Rheumatoid Arthritis
10/26
10/27
ITHACA, NCT04270409 / 2019-003139-47: Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma

Active, not recruiting
3
337
Europe, Canada, Japan, US, RoW
Isatuximab SAR650984, Sarclisa, Lenalidomide, Dexamethasone, Montelukast or equivalent, Acetaminophen, Diphenhydramine or equivalent, Methylprednisolone or equivalent
Sanofi
Plasma Cell Myeloma
10/30
10/33
ACTRN12617001516370: MOM trial. MOntelukast Myeloma A pilot study to determine whether Montelukast added to standard Chemotherapy improves response in patients who have failed standard Chemotherapy for Multiple Myeloma.

Active, not recruiting
2/3
6
 
Dr Stephen Kenneth O'Mara, Dr Stephen O'Mara
Multiple Myeloma
 
 
2017-004539-36: Study of Montelukast In Children with Sickle Cell Disease

Ongoing
2/3
200
Europe
Montelukast, N/A, Chewable tablet, Montelukast
Great Ormond Street Hospital for Children NHS Foundation Trust
Sleep-disordered breathing, Obstructive Sleep Apnoea, Psychiatry and Psychology [F] - Psychological processes [F02]
 
 
COSMO, NCT04389411: The Covid-19 Outpatient Symptom Montelukast Oximetry Trial

Not yet recruiting
2/3
250
NA
Montelukast 10mg
McGill University, Segal Cancer Centre, The McGill Practice Based Research Network, Lady Davis Institute
COVID-19
01/23
02/25
NCT05293132: Effect of Montelukast Versus Co Enzyme in Sepsis

Completed
2/3
90
RoW
Montelukast Sodium 10 mg, (Singulair®; Merck & Co Inc) or (Clear air®; Amoun Pharmaceutical Company S.A.E., Egypt), Co-Enzyme Q10, Co enzyme Q10(MEPACO Pharmaceutical Company (Egypt), Standard Treatment, Standard sepsis treatment
Ain Shams University
Sepsis
06/23
06/23
NCT04673422: Effect of Montelukast in Preventing Dengue With Warning Signs in Dengue Patients

Completed
2/3
358
RoW
Montelukast, Placebo
Phramongkutklao College of Medicine and Hospital
Dengue, Dengue With Warning Signs, Dengue Shock Syndrome
06/23
06/23
SMILES, NCT04351698: Study of Montelukast in Sickle Cell Disease

Recruiting
2/3
200
Europe
Montelukast, singulair, Oral Placebo
Great Ormond Street Hospital for Children NHS Foundation Trust, Guy's and St Thomas' NHS Foundation Trust, University College London Hospitals, North Middlesex University Hospital, King's College Hospital NHS Trust, The Whittington Hospital NHS Trust
Anemia, Sickle Cell, Sleep-Disordered Breathing
09/24
09/24
NCT06113640: Montelukast in Parkinson Disease

Recruiting
2/3
60
RoW
levodopa-carbidopa, Montelukast
Mostafa Bahaa
Parkinson Disease
11/24
12/25
NCT06747130: Efficacy of Montelukast in Preventing Transaminase Elevation in Adult Dengue Patients

Not yet recruiting
2/3
82
NA
Montelukast, Montelukast Placebo
Phramongkutklao College of Medicine and Hospital
Dengue, Montelukast, Transaminases
01/27
01/27
ChiCTR-IPR-15006578: The efficacy and safety evaluation of Xiao'er Kechuan Granule in children’s Cough Variant Asthma with syndrome of wind invading lung: a randomized, double-blind, double-dummy, parallel, active-controlled, Dose exploration,multi-center clinical trial

Recruiting
2
96
 
Take Xiao'er Kechuan Granule 2 bags,Tid; montelukast (Singulair) placebo,1 pill ,Qn p.o ;Take Xiao'er Kechuan Granule 1 bag and Xiao'er Kechuan Granule placebo 1 bag,Tid; montelukast (Singulair) placebo,1 pill ,Qn p.o ;Take Xiao'er Kechuan Granule placebo 2 bags,Tid; montelukast (Singulair) placebo,1 pill ,Qn p.o ;Take Xiao'er Kechuan Granule 2 bags,Tid; montelukast (Singulair),1 pill ,Qn p.o
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; Level of the institution：, Beijing Sihuan Kebao Pharmaceutical Co., Ltd.
Cough Variant Asthma
 
 
NCT04551755: Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19

Not yet recruiting
2
188
NA
Ivermectin and Doxycycline, Placebo
Bangladesh Medical Research Council (BMRC)
Covid19
11/20
12/20
2020-000715-71: The assessment of cysteinyl leuktriene receptor antagonist (montelukast) role in inhibition of atherosclerosis in patients undergoing endovascular treatment due to peripheral arterial disease. Ocena wpływu zastosowania antagonisty receptora leukotrienowego (montelukast) na zahamowanie rozwoju miażdżycy zarostowej tętnic u pacjentów leczonych wewnątrznaczyniowo z powodu niedokrwienia kończyn dolnych

Not yet recruiting
2
200
Europe
Tablet, Asmenol
Jagiellonian University Medical College, National Science Centre
Occlusive atherosclerosis in patients treated endovascularly due to ischemia of the lower limbs in the course of obstructive artery disease. Miażdżyca zarostowa tętnic u pacjentów leczonych wewnątrznaczyniowo z powodu niedokrwienia kończyn dolnych w przebiegu miażdżycy zarostowej tętnic., Ischemia of the lower limbs in the course of obstructive artery disease Niedokrwienie kończyn dolnych w przebiegu miażdżycy tętnic kończyn dolnych., Diseases [C] - Cardiovascular Diseases [C14]
 
 
2020-000148-76: Effects of the Montelukast drug on brain inflammation in Parkinson's disease.

Not yet recruiting
2
15
Europe
Montelukast Krka, Film-coated tablet, Montelukast
Stockholm Health Care Services, Axel och Margaret Ax:son Johnson’s foundation
Parkinson's disease, Parkinson's disease, Diseases [C] - Nervous System Diseases [C10]
 
 
ChiCTR2000039630: Phase II clinical trial of the superiority of montelukastine in combination with TPO-MPL agonists for the treament of primary immune thrombocytopenia

Recruiting
2
102
 
Montelukast sodium 10mg/day; rhTPO 15000 units ;rhTPO 15000 units
Department of Hematology, Second Medical Center, Chinese PLA General Hospital; Chinese PLA General Hospital, Hospital research projects
Primary immune thrombocytopenia
 
 
NCT04718285: Investigation the Effect of Montelukast in COVID-19

Recruiting
2
380
RoW
Montelukast Oral Tablet, Montelukast plus Favicovir (Favipiravir), Favicovir (Standard Treatment)
Bahçeşehir University, Medipol University, The Scientific and Technological Research Council of Turkey
COVID-19, SARS-CoV-2
05/22
06/22
ISAKIDS, NCT03860844 / 2018-002697-45: Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Hourglass Jan 2022 - Dec 2022 : From trial in pediatrics with r/r AML/ALL
Terminated
2
67
Europe, US, RoW
Isatuximab, SAR650984, Sarclisa, Dexamethasone or equivalent, Fludarabine, Cytarabine, Liposomal daunorubicin, Daunorubicin (nonliposomal), Idarubicin, Filgrastim or equivalent, Mitoxantrone, Doxorubicin, Vincristine, Pegaspargase (PEG) Asparaginase, Cyclophosphamide, Etoposide, Methotrexate, L - Asparginase, Hydroxyurea, L - Asparaginase (Erwinase)
Sanofi
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
09/22
05/23
NCT05447520: Montelukast Use in Rheumatoid Arthritis

Completed
2
92
RoW
Montelukast, Placebo, Conventional DMARDs
Noha Mansour
Rheumatoid Arthritis
12/22
12/22
2022-000974-25: Evaluation of Amivantamab Infusion Related Reaction Mitigation Evaluación de la Mitigación de las Reacciones Relacionadas con la Infusión de Amivantamab.

Not yet recruiting
2
120
Europe
Lazertinib mesylate monohydrate, Amivantamab, Dexamethasone, Montelukast Sodium, Methotrexate, JNJ-73841937-ZCY/YH25448AM, JNJ-61186372, Film-coated tablet, Concentrate for solution for infusion, Tablet, Injection, Dexamethasone, Montelukast Sodium, Methotrexate
Janssen-Cilag International NV, Janssen Research & Development, LLC
EGFR-mutated Advanced or Metastatic Non-small Cell Lung Cancer Mutación del EGFR en Cáncer de Pulmón No Microcítico avanzado o metastásico, A specific type of lung cancer called "Non-Small Cell Lung Cancer Tipo específico de Cáncer de Pulmón llamado "Cáncer de Pulmón No Microcítico", Diseases [C] - Cancer [C04]
 
 
2020-005135-73: A clinical trial to evaluate the safety and the efficacy of a combination of Rupatadine and Montelukast compared to Rupatadine in patients with allergic rhinitis Un ensayo clínico para evaluar la seguridad y la eficacia de la combinación de rupatadina y montelukast en comparación con solo rupatadina en pacientes con rinitis alérgica

Not yet recruiting
2
300
Europe, RoW
Rupatadine, Montelukast, Tablet, Rupatadina Uriach 10 mg comprimidos EFG, SINGULAIR 10 mg COMPRIMIDOS RECUBIERTOS CON PELICULA
Biohorm S.L, Biohorm, S.L., Biohorm S.L, Biohorm, S.L.
Seasonal allergic rhinitis with and without mild to moderate bronchial asthma Rinitis alérgica estacional con y sin asma bronquial leve a moderada, Seasonal alergic rhinitis with or without asthma Rinitis alérgica estacional con y sin asma, Diseases [C] - Immune System Diseases [C20]
 
 
NCT04198623: Efficacy of Montelukast in Reducing the Incidence and Severity of Monoclonal Antibodies Associated Infusion Reactions

Completed
2
40
US
Montelukast 10 Mg Oral Tablet, Singulair
University of California, San Francisco
Infusion Reaction, Monoclonal Antibody
07/24
07/24
NCT05704049: A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Active, not recruiting
2
74
Europe, Japan, RoW
Isatuximab, Carfilzomib, Kyprolis, Dexamethasone, Dexamethasone IV, Montelukast, Acetaminophen, Diphenhydramine, Methylprednisolone
Sanofi
Relapsed/Refractory Multiple Myeloma
11/24
03/27
SKIPPirr, NCT05663866: Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Active, not recruiting
2
73
Europe, US, RoW
Dexamethasone, Montelukast, Methotrexate, Amivantamab, JNJ-61186372, Lazertinib, JNJ-73841937
Janssen Research & Development, LLC
Carcinoma, Non-Small-Cell Lung
03/24
10/25
NCT05922761: BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

Recruiting
2
45
US
Belumosudil, Rezurock, KD025, 2-{3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy}-N-(propan-2-yl) acetamide, C26H24N6O2, Fluticasone, Fluticasone Propionate, Azithromycin, Zithromax, Prednisone, Montelukast, Singulair
Dana-Farber Cancer Institute, Sanofi, National Heart, Lung, and Blood Institute (NHLBI)
Bronchiolitis Obliterans Syndrome, Bronchiolitis Obliterans, Lung Diseases, Chronic Graft Versus Host Disease
06/26
12/26
SubQSA, NCT06356571: A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Recruiting
2
64
US
Isatuximab SC-OBDS, SAR650984, Sarclisa, Montelukast, Dexamethasone, Acetaminophen, Diphenhydramine, Methylprednisolone, Carfilzomib
Sanofi
Plasma Cell Myeloma Refractory
01/27
07/27
NCT05807048: Daratumumab in STK11 Mutated NSCLC

Recruiting
2
14
US
Daratumumab and Hyaluronidase-fihj, DARZALEX FASPRO, Pre-Intervention Medication, Post-Intervention Medication
NYU Langone Health
Non-small Cell Lung Cancer With STK11/LKB1 Mutation
05/26
12/26
TEAM, NCT05819541: Treating Exacerbations of Asthma With Oral Montelukast in Children

Recruiting
2
90
US
Montelukast Oral Granules, Singulair, Albuterol, Inhaled albuterol, Corticosteroid, Systemic corticosteroid
Vanderbilt University Medical Center
Status Asthmaticus
06/25
10/25
FLASH, NCT05251259 / 2021-003338-35: Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-Severe Uncontrolled Asthma

Recruiting
2
666
Europe, Japan, US, RoW
Atuliflapon, AZD5718, Placebo
AstraZeneca, AstraZeneca AB
Asthma
01/26
01/26
NCT04268498: A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma

Recruiting
2
306
Europe, US
Bortezomib, Dexamethasone, Lenalidomide, Revlimid, Acetaminophen, Diphenhydramine, Montelukast, Carfilzomib, Daratumumab, Autologous Stem Cell Transplant (ASCT)
University of Miami, Amgen, Janssen Pharmaceuticals
Multiple Myeloma
02/27
02/27
NCT03277170: Pragmatic RCT of High-dose Oral Montelukast for Moderate and Severe Pediatric Acute Asthma Exacerbations

Withdrawn
2
320
US
Montelukast Oral Granules, Singulair
Vanderbilt University Medical Center
Asthma; Status, Asthma in Children, Asthma Acute, Asthma Attack, Acute Asthma Exacerbation
08/28
09/29
Iber-KDd, NCT05896228: Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone () in Patients with Relapsed/Refractory Multiple Myeloma

Recruiting
2
30
US
Iberdomide, Carfilzomib, Daratumumab, Dexamethasone, Acetaminophen, Diphenhydramine, Montelukast
Benjamin T Diamond, MD, Bristol-Myers Squibb
Refractory Multiple Myeloma, Relapsed Multiple Myeloma
03/29
03/31
NCT05143502: Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.

Active, not recruiting
1/2
60
RoW
Montelukast, Prednisolone, Fluticasone Furoate
Assiut University
Montelukast, Chronic Rhinosinusitis With Nasal Polyps
01/24
03/24
ACTRN12618001112257: A long term follow up study of ATX-101 given by intravenous infusion once every week in patients with advanced solid tumours.

Recruiting
1
36
 
Therapim Pty Ltd, Therapim Pty Ltd
Advanced Solid Tumors
 
 
EQUULEUS, NCT01998971: A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma

Checkmark The positive opinion of the CHMP on split dosing regimen for Darzalex
Nov 2018 - Nov 2018: The positive opinion of the CHMP on split dosing regimen for Darzalex
Checkmark Filed for a split dosing regimen
Aug 2018 - Aug 2018: Filed for a split dosing regimen
Checkmark Filed for Type II Variation of a split dosing regimen
More
Completed
1
240
Europe, US
Daratumumab, Velcade, Pomalidomide, Dexamethasone, Melphalan, Prednisone, Thalidomide, Diphenhydramine, Acetaminophen, Carfilzomib, Lenalidomide, Montelukast
Janssen Research & Development, LLC
Multiple Myeloma
01/19
01/24
ChiCTR2300075040: Effect of preoperative application of antiallergic drugs on adenoid pathology and postoperative recovery

Completed
1
20
 
Administration of the anti-allergy drug montelukast sodium ;Placebo control
Dalian municipal Central Hospital; Dalian municipal Central Hospital, Postgraduate research funding
Adenoid hypertrophy
 
 
NCT04075110: Investigation the Safety and Efficacy of The Antileukotriene Agents, Montelukast, as Adjuvant Therapy in Obese Patients With Type 2 Diabetes Mellitus

Completed
1
100
RoW
Montelukast 10mg, Placebo
Sadat City University
Obesity; Endocrine; Diabetes Type 2
06/22
04/23
NCT05852769: A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Completed
1
18
US
BMS-986196, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, Pravastatin
Bristol-Myers Squibb
Healthy Volunteers
08/23
08/23
NCT05607446: To Evaluate the Efficacy and Safety of TQC3564 Tablets in the Treatment of Persistent Allergic Rhinitis

Terminated
1
12
RoW
TQC3564 tablets, Placebo tablets, TQC3564 tablets, montelukast sodium tablets, Placebo tablets, montelukast sodium tablets
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Allergic Rhinitis
05/23
12/23
MOCHA, NCT04572256: MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction ( Trial)

Recruiting
1
30
US
Montelukast, Singulair, Placebo
Austin V Stone, Duke University, The Cleveland Clinic, University of California, San Francisco
ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
04/25
04/25
NCT05381207: Impact Of Montelukast On Allergic Rhinitis And Its Inflammatory Makers

Not yet recruiting
1
60
NA
Montelukast Oral Tablet, Fluticasone Furoate nasal spary
Assiut University
Allergic Rhinitis
10/24
10/24
Clinical and basic research on adenoid hypertrophy in children, ChiCTR2400083549: Clinical and Basic Research on Yinbei Granules in the Treatment of Children with Adenoid Hypertrophy and Phlegm Accumulation Syndrome

Recruiting
1
100
 
Honeysuckle 9g, Fritillaria thunbergii 9g, Forsythia suspensa 9g, oyster 15g, burdock 9g, magnolia 6g, mint 6g, Atractylodes macrocephala 9g, Astragalus membranaceus 9g. Usage: The above traditional Chinese medicine granules are provided by Sichuan New Green Pharmaceutical Company< 1/2 dose per day for 3-year-old individuals and 1 dose per day for 3-6-year-old individuals. Rinse with warm water and take in separate doses in the morning and evening. Each course lasts for 4 weeks, with a total of 3 courses.; Oral administration of Montelukast sodium tablets: 3+~6 years old, 4mg each time, once every night; 6+to 14 years old, 5mg per dose, once per night. Pingqi (Menglujite Sodium Tablets), Lunanbeite Pharmaceutical Co., Ltd., Product Approval Number: National Pharmaceutical Approval Letter H20083372. Each course lasts for 4 weeks, with a total of 3 courses.
Shanghai Municipal Hospital of Traditional Chinese Medicine; Shanghai Municipal Hospital of Traditional Chinese Medicine, Task Book for the Construction of the Three Year Action Plan for Further Accelerating the Inheritance, Innovation and Development of Traditional Chinese Medicine in Shanghai - ZY (2021-2023) -0209-05
adenoidal hypertrophy
 
 
NCT06887673: Lipid Mediators & Cancer: Montelukast, SPM, and Almonds

Not yet recruiting
1
56
US
No Interventions, Sports Pro Resolve 4 g, Double Wood SPM 4 g, 20 California Sweet Almonds, Montelukast 10 Mg Oral Tablet, Montelukast 10 Mg Oral Tablet and SPM 4 g, Cold- Pressed Almond Oil 30 mL
University of South Florida
Colorectal Cancer, Sarcoma, Brain Tumors, Endometrial Cancer, Ovarian Cancer
03/26
03/26
(GWI), NCT05992311: Clinical Evaluation of Montelukast in Veterans with Gulf War Illness

Not yet recruiting
1
80
US
Montelukast, Singulair, Placebo
Baylor College of Medicine, Michael E. DeBakey VA Medical Center, Texas A&M University
Gulf War Syndrome
04/28
08/28
ChiCTR-TRC-09000688: Receptor Antagonist in the Treatment of Allergic Rhinitis

Completed
N/A
46
 
Montelukast 26 weeks per subject versus placebo
Prof. Albert Martin Li; Level of the institution：, MSD
asthma, allergic rhinitis
 
 
ChiCTR-OCC-13004324: The Effect of Jade Screen Powder on IgE and Eosinophils in Childhood Asthma of stable situation

Completed
N/A
500
 
Budesonide ;Montelukast ;Budesonide & JSP ;Montelukast & JSP ;JSP
Department of Pediatrics, Shanghai TCM-Integrated Hospital; Shanghai TCM-Integrated Hospital, TCM developing office of Shanghai health Bureau
childhood asthma
 
 
ChiCTR-OOC-15005841: Montelukast Sodium Tablets treatment clinical study for intractable cough by idiopathic pulmonary fibrosis

Recruiting
N/A
60
 
Montelukast Sodium Tablets: oral, 1 tablets each time (10mg), 1 time a day, at bedtime, for a period of 12 weeks ;Don't take Montelukast Sodium Tablets
Shanghai Pulmonary Hospital; None, no funding
Idiopathic pulmonary fibrosis
 
 
ChiCTR-INR-17010689: Clinical Study of Patients with Airway Hyperresponsiveness companied by Cough Variant Asthma

Completed
N/A
60
 
Allergy Decoction & Montelukast ;Montelukast
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University; Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Hospital-level Project Fund
CVA
 
 
LT and BPD, ChiCTR-ORN-16008890: Research on relationship of leukotrienes and bronchopulmonary dysplasia

Recruiting
N/A
200
 
therapy of Montelukast
First affiliated hospital of Nanjing Medical University; First affiliated hospital of Nanjing Medical University, self-financing
Bronchopulmanary dysplasia
 
 
ChiCTR-IOR-17012434: Clinical Observation of Chinese medicine acupoint sticking Combined with Montelukast in Treating Allergic Rhinitis in Children

Recruiting
N/A
180
 
Chinese medicine acupoint sticking Combined with Montelukast ;Chinese medicine acupoint sticking ;Montelukast
Shanghai Children's Medical Center Affiliated Shanghai Jiao Tong University; Shanghai Children's Medical Center, Shanghai Scinece and Technology Commission
allergic rhinitis
 
 
ChiCTR-IOR-17010765: Study on the curative evaluation of the Gufei Tang in the treatment of combined allergic rhinitis and asthma syndrome

Recruiting
N/A
106
 
Granule of Gufei Tang plus Montelukast Sodium Tablets ;Placebo granule of Gufei Tang plus Montelukast Sodium Tablets
Guangdong Provincial Hospital of Chinese Medicine; Guangdong Provincial Hospital of Chinese Medicine, Special subject construction of Guangdong high level University
Combined allergic rhinitis and asthma syndrome
 
 
NCT04561687: Comparison of Montelukast and Azelastine in Treatment of Moderate to Severe Allergic Rhinitis

Recruiting
N/A
66
RoW
Montelukast, Azelastine, Budesonide, Placebo
Shiraz University of Medical Sciences
Allergic Rhinitis
09/21
12/21
NCT04621513: Collaborative Care Model for Allergic Rhinitis With Obstructive Sleep Apnea From Prevention to Treatment.

Recruiting
N/A
60
RoW
laser acupuncture (RJ laser S/N 1813458), western medicine, intra-nasal corticosteroid(AVAMYS) with Montelukast (singulair)
China Medical University Hospital
Pediatric Sleep Apnea
12/21
12/22
ChiCTR2000032153: Clinical study on the treatment of chronic persistent stage of bronchial asthma with the method of Jieyu Sufei Decoction

Not yet recruiting
N/A
66
 
JieYuSuFei decoction ;Montelukast sodium tablets and/or Salmeterol ticasone powder inhaler
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine; Xiyuan Hospital, Chinese Academy of traditional Chinese Medicine, Xiyuan Hospital, Chinese Academy of traditional Chinese Medicine
Asthma
 
 
NCT04322422: Clinical Characteristics and Treatment of Chest Tightness Variant Asthma

Recruiting
N/A
300
RoW
Inhaled corticosteriod/long-acting beta-agonist plus Montelukast, Inhaled corticosteriod/long-acting beta-agonist only
Second Affiliated Hospital, School of Medicine, Zhejiang University
Asthma, Chest Syndrome, Clinical Anxiety, Clinical Depression, Lung Function, Quality of Life, Eosinophilia, Nitric Oxide, Airway Responsiveness, Induced Sputum
07/22
12/22
ChiCTR2100052064: The efficacy of sanjietongqiao prescription in the treatment of children with adenoid hypertrophy

Not yet recruiting
N/A
60
 
Sanjietongqiao prescription ;Montelukast Sodium (MS) combined with Mometasone Furoate Nasal Spray Nasal Spray (MFNSNS)
Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Shandong University of Chinese Medicine, Self-funded
adenoid hypertrophy
 
 
ChiCTR1900028522: Nasal eosinophilia in nasal smears of patients with chronic rhinitis

Recruiting
N/A
600
 
Budesonide nasal spray ;Budesonide nasal spray+montelukast ;Budesonide nasal spray +Loratadine
Jinhua Hospital of Zhejiang University; Jinhua Central Hospital, the Young and Middle-aged Research Startup Fund of Jinhua Central Hospital
chronic rhinitis
 
 
NCT05457855: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Montelukast vs Fluticasone

Active, not recruiting
N/A
75678
US
Montelukast, Fluticasone
Brigham and Women's Hospital, National Institute on Aging (NIA), Rutgers University, Johns Hopkins University
Asthma
07/23
12/23
 

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