budesonide / Generic mfg. 
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  • ||||||||||  budesonide / Generic Mfg.
    IS INHALED STEROID-FORMOTEROL ESSENTIAL FOR SUCCESS IN ASTHMA ACTION PLANS? () -  Nov 21, 2019 - Abstract #APSR2019APSR_186;    
    Several recent studies report that inhaled combined Budesonide-Formoterol as needed may be better than regular inhaled steroids in mild asthma [N Engl J Med...We conclude the SMART-KILAT is not superior to KILAT with other inhalational drugs in AAP. This suggests that it is the timeliness of treatment escalation during AAEs rather than steroid-formoterol itself which is essential for AAP success.
  • ||||||||||  budesonide / Generic mfg.
    Clinical, Retrospective data, Journal:  Features of Adult Autoimmune Enteropathy Compared With Refractory Celiac Disease. (Pubmed Central) -  Nov 19, 2019   
    In a retrospective study of 30 patients with AIE, followed for a median 28 months, we found this disease to have has distinct demographic, clinical, and histologic characteristics compared to refractory celiac disease type 1. Most patients with AIE (85%) have a clinical response to budesonide, all of whom were unsuccessfully treated with conventional therapies.
  • ||||||||||  budesonide / Generic mfg.
    Journal:  Topical Corticosteroid Pretreatment Mitigates Cellular Damage After Caustic Injury to the Nasal Upper Airway Epithelium. (Pubmed Central) -  Nov 19, 2019   
    Topical corticosteroid treatment to the nasal epithelium can mitigate several of the early deleterious effects of acute epithelial damage in experimental airway injuries caused by TCA. These findings suggest a novel, direct cytoprotective effect of corticosteroids on the nasal epithelium, and the potential of expanding the use of prophylactic periprocedural topical corticosteroids for respiratory epithelial tissues.
  • ||||||||||  budesonide / Generic Mfg.
    Clinical, Journal:  Off-label use of Budesonide suspensions to treat a patient with lymphocytic esophagitis (Pubmed Central) -  Nov 14, 2019   
    These findings suggest a novel, direct cytoprotective effect of corticosteroids on the nasal epithelium, and the potential of expanding the use of prophylactic periprocedural topical corticosteroids for respiratory epithelial tissues. Our case report is meant to describe an empirical therapeutic concept, which led to clinical and histological remission of chronic LyE.
  • ||||||||||  budesonide oral (TAK-721) / Takeda
    BUDESONIDE ORAL SUSPENSION TREATMENT IMPROVES DYSPHAGIA SYMPTOMS IN PATIENTS WITH EOSINOPHILIC ESOPHAGITIS () -  Nov 13, 2019 - Abstract #ACAAI2019ACAAI_991;    
    P3
    A maintenance study assessing long-term response (SHP621-302) is on-going. Figure caption:Data are mean (SD) unless otherwise stated.b.i.d., twice daily (every morning after meals and at bedtime); BMI, body mass index; DSQ, dysphagia symptom questionnaire; EoE HSS, eosinophilic esophagitis histologic scoring system; eos, eosinophils; EREFS, Endoscopic Reference Score; hpf, high-powered field; SD, standard deviation; aCategories included White, Black or African American, Native Hawaiian or Other Pacific Islander, Asian, American Indian or Alaska Native or Other; bDSQ combined score relates to the frequency and intensity of dysphagia events; cTotal grade and stage score ratios are normalized to the number of non-missing sections analyzed.
  • ||||||||||  budesonide / Generic Mfg.
    Clinical, Journal:  Moving from efficacy to effectiveness: budesonide multimatrix in ulcerative colitis. (Pubmed Central) -  Nov 9, 2019   
    Figure caption:Data are mean (SD) unless otherwise stated.b.i.d., twice daily (every morning after meals and at bedtime); BMI, body mass index; DSQ, dysphagia symptom questionnaire; EoE HSS, eosinophilic esophagitis histologic scoring system; eos, eosinophils; EREFS, Endoscopic Reference Score; hpf, high-powered field; SD, standard deviation; aCategories included White, Black or African American, Native Hawaiian or Other Pacific Islander, Asian, American Indian or Alaska Native or Other; bDSQ combined score relates to the frequency and intensity of dysphagia events; cTotal grade and stage score ratios are normalized to the number of non-missing sections analyzed. No abstract available
  • ||||||||||  Remicade (infliximab) / Mitsubishi Tanabe, J&J, budesonide / Generic Mfg., Humira (adalimumab) / Eisai, AbbVie
    Clinical, Journal:  Single-centre experience with anti-tumour necrosis factor treatment in budesonide-refractory microscopic colitis patients. (Pubmed Central) -  Nov 9, 2019   
    Over half of budesonide-refractory microscopic colitis patients can achieve clinical remission or response on anti-tumour necrosis factor agents. Prospective studies are mandatory to evaluate the efficacy and safety of anti-tumour necrosis factor treatments in budesonide-refractory microscopic colitis.
  • ||||||||||  budesonide / Generic Mfg.
    RAPID ONSET OF ACTION OF A NOVEL BUDESONIDE NASAL SPRAY IN GRASS POLLEN ALLERGIC RHINITIS (Monitor 10) -  Nov 9, 2019 - Abstract #ACAAI2019ACAAI_964;    
    Total nasal symptom score (TNSS) (y- axis) of Budesolv (blue line) and placebo (orange line) during grass pollen allergen challenge; indicated are measurements taken every 15 minutes from time point 0 (time point 1) until 6 hours (time point 25) (x- axis). Significant differences between groups are indicated by asterisks (*).
  • ||||||||||  budesonide / Generic Mfg.
    ALLERGIC CONTACT DERMATITIS ON THE EAR: NOT COMMONLY HEARD OF (Monitor 6) -  Nov 9, 2019 - Abstract #ACAAI2019ACAAI_852;    
    Pictures five and seven days after patch removal showed papule, vesicles and blistering. Discussion There is a need to create awareness of allergic contact dermatitis to topical agents including antibiotics and corticosteroids in recalcitrant or recurrent dermatitis.
  • ||||||||||  budesonide / Generic Mfg.
    ALLERGIC FUNGAL RHINOSINUSITIS, A RARE FORM OF CHRONIC RHINOSINUSITIS (Monitor 5) -  Nov 9, 2019 - Abstract #ACAAI2019ACAAI_840;    
    The diagnostic criteria for AFRS require the presence of CRS with nasal polyposis, eosinophilic mucin, IgE-mediated allergy to fungus, and no evidence of invasive fungal disease, diabetes mellitus, or immunodeficiency. The main purpose of this case is to discuss the management of allergic fungal rhinosinusitis, and difficulty in controlling symptoms without prompt surgical debridement.
  • ||||||||||  sirolimus / generics
    ALTERNATIVE TREATMENT FOR A PATIENT WITH PHOSPHOINOSITIDE-3-KINASE DELTA (PI3KD) DEFECT (Monitor 4) -  Nov 9, 2019 - Abstract #ACAAI2019ACAAI_753;    
    Fecal Calprotectin is being utilized as a non-invasive stool bio-marker for inflammation and medication adjustments. His case highlights, as more APDS patients with varied clinical presentations are identified - new alternative therapies continue to emerge.
  • ||||||||||  budesonide / Generic Mfg.
    ORAL BUDESONIDE DESENSITIZATION: A CASE REPORT (Monitor 1) -  Nov 9, 2019 - Abstract #ACAAI2019ACAAI_664;    
    A limitation of this case was that the diagnosis of budesonide allergy was made through clinical history, we were unable to confirm the diagnosis by skin testing. The patient has been seen in our clinic for follow-up and has been tolerating oral budesonide well without any reoccurrence of angioedema.
  • ||||||||||  Remicade (infliximab) / Mitsubishi Tanabe, J&J, Stelara (ustekinumab) / J&J
    EOSINOPHILIA WHILE ON CROHN’S THERAPY WITH INFLIXIMAB (Monitor 2) -  Nov 9, 2019 - Abstract #ACAAI2019ACAAI_637;    
    His Crohn’s disease remained well-controlled and his eosinophil normalized over the next 6 months to an AEC of 500. EGD showed normal mucosa while on swallowed budesonide and four-food elimination.
  • ||||||||||  Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  APRiCCOT: Antibiotics and Hydroxychloroquine in Crohn's (clinicaltrials.gov) -  Oct 31, 2019   
    P2,  N=59, Completed, 
    Key areas of research include repeated surfactant administration, using surfactant as a vehicle for budesonide and stem cell therapy. Recruiting --> Completed | N=100 --> 59 | Trial completion date: Dec 2019 --> Sep 2019 | Trial primary completion date: Dec 2019 --> Apr 2019
  • ||||||||||  budesonide / Generic Mfg.
    Review, Journal:  Microscopic colitis: diagnosis and management. (Pubmed Central) -  Oct 29, 2019   
    Several treatment options exist, but budesonide is the only treatment proven in randomised-controlled trials to be effective and safe for induction and maintenance of remission. This article provides a practical overview for the gastroenterologist looking after patients with MC.
  • ||||||||||  budesonide / Generic Mfg., Nucala (mepolizumab) / GSK
    Journal:  Efficacy of Pharmacologic Therapy for Eosinophilic Esophagitis: A Systematic Review and Network Meta-Analysis. (Pubmed Central) -  Oct 24, 2019   
    Among patients with asthma, switching to BF Spiromax was associated with reduced exacerbations, reduced SABA use and improved treatment stability versus continuing on BF Turbuhaler. On the basis of this network meta-analysis, viscous budesonide was shown to be the most effective pharmacologic therapy for EoE among the reported pharmacologic treatments.
  • ||||||||||  budesonide / Generic Mfg.
    Clinical, Journal:  Montelukast and Budesonide for Childhood Cough Variant Asthma. (Pubmed Central) -  Oct 24, 2019   
    Curative effects on young children with cough variant asthma of montelukast combined with budesonide are significant. The therapy may improve clinical symptoms and pulmonary function and reduce serum inflammatory factor level of sick children, with high application value and worthy of application and promotion.
  • ||||||||||  budesonide / Generic Mfg.
    What you didn't know about budesonide (Ernest N. Morial Convention Center - Exhibit Hall - Learning Theater 3) -  Oct 23, 2019 - Abstract #CHEST2019CHEST_4579;    
    A retrospective review of the budesonide molecule and its history. Challenge your assumptions, revisit data and learn new information as this session takes you into a deep dive of budesonide’s mechanism, unique characteristics, and other considerations.
  • ||||||||||  budesonide / Generic Mfg.
    Journal:  Nanoporous CD-MOF particles with uniform and inhalable size for pulmonary delivery of budesonide. (Pubmed Central) -  Oct 18, 2019   
    When Rhodamine B was carried by the DPI particles, the fluorescence signal at the lung tissue was markedly improved after cholesterol modification compared with CD-MOF, whilst the bioavailability of CHO-CD-MOF-BUD in rat was equivalent with that of the commercial product of Pulmicort Turbuhaler. Therefore, the CD-MOF powders modified by cholesterol can be used as a promising inhalable carrier for pulmonary delivery of drugs with small dose.
  • ||||||||||  Remicade (infliximab) / Mitsubishi Tanabe, J&J, Humira (adalimumab) / Eisai, AbbVie
    Retrospective data, Review, Journal:  Interventions for maintenance of surgically induced remission in Crohn's disease: a network meta-analysis. (Pubmed Central) -  Oct 18, 2019   
    Evidence on the safety of the interventions was inconclusive, however cases of pancreatitis and leukopenia from purine analogues were evident in the studies. Larger trials are needed to further understand the effect of the interventions on endoscopic relapse.