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20 Diseases |  |
17 Trials |
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- || budesonide / Generic mfg.
How about budesonide? Does that help with outcomes? (Twitter) - May 18, 2022
- | budesonide / Generic mfg.
Journal: Systemic allergic dermatitis due to budesonide patch testing. (Pubmed Central) - May 15, 2022
No abstract available
- || budesonide / Generic mfg.
Review: Quantitative comparison of different inhaled corticosteroids in the treatment of asthma in children. (Pubmed Central) - May 14, 2022
This study analyzed the entire time-course of the drug efficacy of Inhaled corticosteroids in the treatment of asthma in children aged 5-12, which found that although the maximum efficacy of both ciclesonide and budesonide was the same, the onset speed of ciclesonide was faster than that of budesonide. The above information provides the necessary quantitative information for the implementation of medication guidelines for steps 2-3 asthma in children.
- | budesonide / Generic mfg., methotrexate / Generic mfg.
Journal: Gastrointestinal Conditions: Inflammatory Bowel Disease. (Pubmed Central) - May 12, 2022
Surgery (complete resection of involved colon) can be curative in UC. In CD, surgery typically is only used for complications or refractory disease.
- || loratadine / Generic mfg., budesonide / Generic mfg.
Retrospective data, Review, Journal: Evaluation of efficiency and safety of combined loratadine and budesonide in patients with anaphylactic rhinitis: A protocol for systematic review and meta-analysis. (Pubmed Central) - May 12, 2022
Without correct data or information, there is a need for Publication bias, which is assessed by performing the Begg and Egger test and generating a funnel plot. The study provides a trustable clinical foundation for loratadine and budesonide for AR treatment.OSF registration number: DOI 10.17605/OSF.IO/M2RFGEthics and dissemination: Because the present study is founded on existing studies, it does not require ethics approval.
- || budesonide / Generic mfg.
And in this book a chapter “The Dogs That Didn’t Bark” for all of the research that could easily have been done but wasn’t Masks Replicate budesonide All The Ivermectins (to get them to pipe down) Airplane exposure What the hell was NIH doing with their billions of research $? (Twitter) - May 11, 2022
- ||| budesonide / Generic mfg.
But 'gorilla glue-balls' felt like large cancer metastasis. Treatment with nebulized budesonide and mechanical chest percussion cleared it up with one or two treatments. (Twitter) - May 11, 2022
- | budesonide / Generic mfg.
Retrospective data, Journal: Inhaled corticosteroids increase risk of nontuberculous mycobacterial lung disease: a nested case control study and meta-analysis. (Pubmed Central) - May 11, 2022
In addition, budesonide had a smaller impact on the risk of NTM-LD than other ICS medications. The present study and meta-analysis provided evidence for ICS adjustment including dose, discontinuation effect and medications to possibly reduce the risk of NTM-LD.
- Tarpeyo (budesonide) / Calliditas, Stada
NEFECON® (BUDESONIDE) IS AN EPIGENETIC MODIFIER IN IGA NEPHROPATHY (Hall S03) - May 5, 2022 - Abstract #ERAEDTA2022ERA_EDTA_561;
P2
Treatment with Nefecon ® 16 mg/day for 9 months selectively downregulated exosomal miR-122-5p, while having no effect on exosomal miR-483-5p levels, arguing against a generalized ‘anti-miR’ effect of Nefecon ® . Studies are ongoing to both precisely delineate the cellular source(s) of these exosomes and determine the downstream impact of these changes on glomerular and tubulointerstitial biology.
- | fluocinonide / Generic mfg., budesonide / Generic mfg.
Journal: Determination and level investigation of 45 hormones in edible bird's nest by solid phase extraction-high performance liquid chromatography-tandem mass spectrometry (Pubmed Central) - May 5, 2022
The results showed that the levels of hormones in EBNs were much lower than those in eggs, milk, and dairy products for daily consumption. Based on this investigation, the health effect of the hormones in EBNs may be insignificant.
- || budesonide / Generic mfg.
Agree. Use a lot for PO/PR mesalamine. I have also used for budesonide vials (EOE) and PPIs when plan coverage stinks. (Twitter) - May 2, 2022
- ||| famotidine / Generic mfg., fluvoxamine / Generic mfg., budesonide / Generic mfg.
On my 3rd infection. LC since Mar 20. Utterly sick of this shit. Caught from a brief visit to the local shop. This time I have ivormectin, Fluvoxamine, Budesonide, famotidine & various supplements. 52 years old & only had Flu 3 times. I am raging. (Twitter) - May 1, 2022
- |||| budesonide / Generic mfg.
Clinical: Something to be said for gut-selective steroids (budesonide as Entocort)>> systemic steroids in this situation. Can slow down intestinal inflammation without a big systemic immunosuppression. But not much prospective data on this approach in the setting of an abscess. #IBD (Twitter) - May 1, 2022
- |||| budesonide / Generic mfg.
Agree with Peter and Amy. Confirm no ongoing abscess and that infection is controlled. Then I would use budesonide, EEN (controls inflammation and improves outcomes if they come to surgery) and look at commencing anti-TNF medications. Would usually try and avoid IV steroids. (Twitter) - Apr 30, 2022
- | dexamethasone / Generic mfg., budesonide / Generic mfg.
Journal: Presumed adrenal insufficiency in neonates treated with corticosteroids for the prevention of bronchopulmonary dysplasia. (Pubmed Central) - Apr 30, 2022
The use of dexamethasone alone was not associated with increased PAI, when adjusted for prematurity-related factors. The combination of budesonide with dexamethasone was significantly associated with increased PAI.
- || dexamethasone / Generic mfg.
Clinical, Journal: Multicenter randomized clinical trial comparing dexamethasone versus placebo in preventing upper airway obstruction after extubation in critically ill children. (Pubmed Central) - Apr 29, 2022
Dexamethasone prior to extubation did not significantly reduce moderate-severe UAO symptoms, except for patients under 2-years of age. Dexamethasone could decrease Taussig score and the need of rescue therapies, as well as reintubation rates in those intubated for more than 5 days.
- | budesonide / Generic mfg.
Journal: Covid-19 Rehabilitation Therapy: A novel strategy to reduce Covid-19 respiratory complications and significantly improve lung function. (Pubmed Central) - Apr 28, 2022
Dexamethasone could decrease Taussig score and the need of rescue therapies, as well as reintubation rates in those intubated for more than 5 days. Covid-19 Rehabilitation Therapy is cost effective,easy and convenient approach to reduce and prevent related pulmonary complications and must be advocated.
- ||| budesonide / Generic mfg.
And we ignored Omicron Ventriculitis in 20 million children, skipped giving budesonide. We ignored cranial lymphatic obstruction and massive posterior demyelination in children believing children to be only mildly ill. (Twitter) - Apr 28, 2022
- | budesonide / Generic mfg.
Journal, IO biomarker: Interplay between nuclear factor-κB, p38 MAPK and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells. (Pubmed Central) - Apr 27, 2022
Here, we explore synergy occurring between synthetic glucocorticoids (dexamethasone and budesonide) and proinflammatory cytokines (IL1B and TNF) on the expression of the toll-like receptor 2 (TLR2)...We conclude that glucocorticoid-plus-cytokine-driven synergy at TLR2 involves GR and NF-κB acting via specific enhancer regions, which combined with inhibition of p38α MAPK promotes TLR2 expression. Subsequent inflammatory effects that occur following TLR2 agonism may be pertinent in severe neutrophilic asthma or chronic obstructive pulmonary disease, where glucocorticoid-based therapies are less efficacious.
- |||| budesonide / Generic mfg.
Adverse events: We used Budesonide Controlled release formulations in IGAN thinking that its action probably at local site as TRF budesonide not available in India. But it resulted in side effects similar to prednisolone. I dont think Budesonide CR is similar to TRF Budesonide (Twitter) - Apr 27, 2022
- || budesonide / Generic mfg.
You just can’t take systemically absorbed steroids forever, but this concern may not be so obvious with budesonide (trial went 24 months) assuming it if affordable to take indefinitely. Agree though we may never know. (Twitter) - Apr 27, 2022
- |||| prednisone / Generic mfg., Tarpeyo (budesonide) / Calliditas, Stada, budesonide / Generic mfg.
Clinical: Is there a real difference in safety/efficacy between Budesonide-XR and Tarpeyo or between moderate doses of oral (Systemic) prednisone and Tarpeyo in IgAN. No one knows, since the necessary studies have never been done, and this situation is likely to remain indefinitely, (Twitter) - Apr 26, 2022
- | budesonide / Generic mfg.
Journal: Continuous flow process for preparing budesonide. (Pubmed Central) - Apr 26, 2022
In another aspect, particle size optimization studies are also performed to get the desired budesonide solid product. A continuous flow process for preparation of budesonide is identified from the present research investigation which can be readily transferred to industrial scale up.
- budesonide / Generic mfg.
A MULTICENTER, OBSERVATIONAL STUDY OF A QUESTIONNAIRE SURVEY ON ANXIETY AND BEHAVIORAL CHANGES FELT BY JAPANESE PATIENTS WITH INFLAMMATORY BOWEL DISEASE DUE TO COVID-19 EPIDEMIC (ePoster - DDW Virtual) - Apr 25, 2022 - Abstract #DDW2022DDW_1391;
Regarding IBD medications, about 80% of the patients were taking 5-ASA, followed by thiopurine (31.4%), biological agents (47.4%), and less than 10% of the patients were taking steroids or budesonide...The percentage of patients with a behavioral change was small. Based on the content of anxiety obtained in this study, we should continue to proactively inform patients about infectious diseases such as SARS-COV-2 and the accompanying accurate information related to IBD management, thereby relieving their anxiety.
- || Veramyst (fluticasone furoate nasal spray) / GSK
Clinical, Review, Journal: Risk of diabetes mellitus during regular long-term inhaled glucocorticoid treatment in COPD patients: narrative review of the literature. (Pubmed Central) - Apr 20, 2022
The inhaled glucocorticoids administered were: fluticasone propionate (7 studies), budesonide (6 studies), mometasone furoate (3 studies), beclomethasone dipropionate (1 study), triamcinolone acetonide (1 study), and fluticasone furoate (1 study) respectively. Only 3 out of the 19 trials identified in our narrative review reported data on diabetes mellitus, and in these the incidence of diabetes mellitus was not significantly different in both treatment arms (inhaled glucocorticoids and placebo), regardless of the type of glucocorticoid used.
- || budesonide / Generic mfg.
Clinical, Review, Journal: Review of efficacy of ciclesonide for the treatment of asthma in children. (Pubmed Central) - Apr 19, 2022
In children with asthma, once-daily CIC significantly improved large and small airway function, asthma symptoms, and asthma control, and reduced rescue medication use compared with placebo. CIC was comparable with other ICS used to treat asthma in children, which demonstrated its worth for the pediatric population.
- || budesonide / Generic mfg., fluticasone / Generic mfg.
Clinical, Review, Journal: Safety of ciclesonide in children with asthma: A review of randomized controlled trials. (Pubmed Central) - Apr 19, 2022
Data from 13 studies demonstrate that CIC is associated with low rates of oropharyngeal AEs, with no indication of clinically relevant systemic effects in children with asthma. The favorable safety profile and demonstrated improvements in asthma control make CIC an ideal inhaled corticosteroid for the treatment of asthma in children.
- | budesonide / Generic mfg.
Journal: Identification and Quantification by NMR Spectroscopy of the 22R and 22S Epimers in Budesonide Pharmaceutical Forms. (Pubmed Central) - Apr 19, 2022
This technique makes it possible to identify budesonide epimers and determine their weight ratio directly, without constructing a calibration curve and using any standards. The results of measuring the 22S epimer content by qNMR are comparable with the results of measurements using the reference HPLC method.
- ||| budesonide / Generic mfg.
How about budesonide and UST (instead of VDZ)? Both VDZ and UST should be pretty safe, and UST seems to be more efficacious for Crohn's (Twitter) - Apr 19, 2022
- ||| budesonide / Generic mfg., Entyvio (vedolizumab) / Takeda
Start with budesonide and vedolizumab, and try to make it to 2 years with non-systemic Rx if possible. Population-level data in Denmark suggest that anti-TNF use after 2 years is suprisingly safe. https://t.co/DpuixKNG5m (Twitter) - Apr 18, 2022
- || budesonide / Generic mfg.
Agree. No role for mesalamine here. Budesonide to facilitate symptom relief as a bridge to vedo. UST is a reasonable alternative as well. (Twitter) - Apr 18, 2022
- || budesonide / Generic mfg.
Options : Budesonide , Vedo , possibly uste And if low risk based on receptor status and stage TNFis after 2 years (Twitter) - Apr 18, 2022
- ||| budesonide / Generic mfg., Tavegil (clemastine) / GSK
Stop inflammation in the brain: budesonide in nebulizer twice a week. Ear drops daily. Osteopathic cranial therapy. Percussion massage to RIB cage. Clemastine for re-myelination, SPHINGOLIN for new BRAIN cells. Elastin for the lungs and cerebral brain vessels, Melatonin and C! (Twitter) - Apr 15, 2022
- | budesonide / Generic mfg.
Journal: Budesonide capsules for peristomal pyoderma gangrenosum. (Pubmed Central) - Apr 15, 2022
The results of measuring the 22S epimer content by qNMR are comparable with the results of measurements using the reference HPLC method. No abstract available
- | budesonide / Generic mfg.
Retrospective data, Journal: Pattern of contact sensitisation in patients with and without atopic dermatitis in an Asian dermatology centre. (Pubmed Central) - Apr 15, 2022
Nickel sulfate was the most frequently sensitizing allergen. The prevalence of contact allergies in atopic patients is comparable to that in non-atopic patients.
- | levofloxacin / Generic mfg., budesonide / Generic mfg.
Preclinical, Journal: In vitro and In silico Interactions of Antiulcer, Glucocorticoids and Urological Drugs on Human Carbonic Anhydrase I and II isozymes. (Pubmed Central) - Apr 14, 2022
Drug-enzyme interactions were also estimated by molecular docking. This study could contribute to the discovery of new drug candidates and as well as target proteins.
- | Tarpeyo (budesonide) / Calliditas, Stada
Journal: First Drug to Reduce Proteinuria in Berger's Disease. (Pubmed Central) - Apr 14, 2022
Budesonide (Tarpeyo) has received accelerated approval to reduce proteinuria in adults with primary immunoglobulin A nephropathy, also known as Berger's disease.Nurses should assess if any coprescribed drugs could induce a drug-drug interaction via the cytochrome P-450 isoenzyme system. Because budesonide causes immunosuppression, patients are at high risk for developing infections and should be told to avoid anyone who is known to have an infection.
- | methotrexate IV / Generic mfg., budesonide / Generic mfg.
Journal: Fecal microbiota transplantation for refractory Clostridioides difficile infection with Crohn's disease in an allogeneic bone marrow transplant recipient (Pubmed Central) - Apr 14, 2022
These interventions resulted in a marked improvement in both CDI and Crohn's disease. Twenty-eight months after FMT, both CDI and Crohn's disease remained in remission with oral mesalamine monotherapy.
- ||| budesonide / Generic mfg., Entyvio (vedolizumab) / Takeda
Clinical: A query on would you consider long-term maintenance for steroid-dependent MC on 6 mg budesonide life-long vs starting a steroid-sparing therapy such as Entyvio? I tend to prefer the latter. (Twitter) - Apr 13, 2022
- |||| budesonide / Generic mfg.
P3 data: Amazing talk by Dr Pietro Canetta on IgA Nephropathy and promising therapies: Targeted release Budesonide: NEFIGARD Phase 3 study. #NKFClinicals @NKF_NephPros (Twitter) - Apr 9, 2022
- ||| budesonide / Generic mfg.
Clinical: Now I'm crying. Now I'm pissed. I took two hours if it took two hours. I found treatment to untwist the occiput and get cervical lymphatics moving. We bought nebulizers and didn't charge for budesonide. I think of 25 million children and I tried to tell everyone - June, July... (Twitter) - Apr 8, 2022
- |||| fluvoxamine / Generic mfg., budesonide / Generic mfg., Paxlovid (nirmatrelvir and ritonavir) / Pfizer
Clinical: Depends on risk of deterioration. If at risk hospitalization/mortality, paxlovid if caught early, fluvoxamine plus inh high dose budesonide if caught late. If fully boosted and imm'competent, probably nothing bc cost/NNT will be higher than NNH. If diabetic or obese, MET or FF. (Twitter) - Apr 7, 2022
- || budesonide / Generic mfg.
What you mean 2 mg of budesonide plus 8 packets of Splenda isn’t scientific enough for you 😂😂😂 (Twitter) - Apr 7, 2022
- || Remicade (infliximab) / Merck (MSD), Mitsubishi Tanabe, J&J, Entyvio (vedolizumab) / Takeda
Review, Journal, Checkpoint inhibition: Pharmacological Interventions for the Prevention and Treatment of Immune Checkpoint Inhibitor-Associated Enterocolitis: A Systematic Review. (Pubmed Central) - Apr 6, 2022
Current treatment recommendations for ICI-associated enterocolitis are based on very low quality evidence, primarily from case reports and case series. Large-scale prospective cohort studies and RCTs are needed to develop prophylactic and therapeutic treatments to minimize interruption or discontinuation of oncological therapies.
- || budesonide / Generic mfg.
Review, Journal: Current treatment of IgA nephropathy. (Pubmed Central) - Apr 5, 2022
Beyond corticosteroids, there is little evidence that any additional immunosuppression is helpful, with the exception of mycophenolate mofetil in patients of Asian descent. A considerable number of clinical trials ranging from enteric coated budesonide to blockade of B-cell function to complement inhibitors are currently ongoing and will hopefully allow a more targeted therapy of high-risk patients with progressive IgAN in the future.
- | zidovudine / Generic mfg., budesonide / Generic mfg.
Journal: Seawater fungi-derived compound screening to identify novel small molecules against dengue virus NS5 methyltransferase and NS2B/NS3 protease. (Pubmed Central) - Apr 5, 2022
Both licensed medications, estramustine (DB01196) and quinestrol (DB04575), were found to be similar to Chevalone E, with prediction scores of 0.818 and 0.856, respectively. In addition, cholic acid (DB02659), acitretin (DB00459), and mupirocin (DB00410) are similar to Sterolic acid, zidovudine (DB00495), imipenem (DB01598), and nadolol (DB01203) are similar to Brocazine A, and budesonide (DB01222) and colchicine (DB01394) are related to Brevione K. These findings suggest that these could be feasible dengue virus treatment options, meaning that more research is needed.
- |||| Tarpeyo (budesonide) / Calliditas, Stada, budesonide / Generic mfg.
Clinical: I fully agree. But, of course, none of the delayed release Budesonide formulations commonly used for IBD have ever been formally tested for efficacy in IgAN. Nor has NEFECON ever been directly compared to moderate dose oral systemic steroids. Questions remain. (Twitter) - Apr 3, 2022
- ||| Tarpeyo (budesonide) / Calliditas, Stada, budesonide / Generic mfg.
Help me understand differences between budesonide-XR preparations, those for GI disorders vs. Tarpeyo for IgAN? I can find nothing to indicate a substantive difference in pharmacology or kinetics of these agents. There are far less expensive generics. Why not use these for IgAN? (Twitter) - Apr 2, 2022
- || budesonide / Generic mfg., favipiravir / Generic mfg.
Rajasthan State India Population 68m Confounder: Less occurrence of deadly Kappa & Alpha+E484 compared to states like Goa & Gujarat. Deaths dropped off a cliff after 600mcg/kg IVM + Doxy Cocktails often with Budesonide, Azithro, HCQ, Favipiravir, Zn, etc Delta was controlled (Twitter) - Mar 31, 2022
- | budesonide / Generic mfg.
Journal: Blood metabolomics in infants enrolled in a dose escalation pilot trial of budesonide in surfactant. (Pubmed Central) - Mar 23, 2022
A subset of glucocorticoid-regulated biochemicals is associated with lung inflammatory status as assessed by lung fluid cytokine concentration. Lower doses of budesonide in surfactant than currently used may provide adequate anti-inflammatory responses in the lung with fewer systemic effects, improving the benefit:risk ratio.