- |||||||||| fentanyl citrate / Generic mfg.
Review, Journal: Fentanyl harm reduction strategies among Latinx communities in the United States: a scoping review. (Pubmed Central) - Aug 17, 2024
Even fewer publications exist on the targeting and cultural adaptation of harm reduction interventions responsive to Latinx communities, especially those using theoretical approaches or frameworks to support these interventions. Future research is needed to assess the unique needs of Latinx populations and to develop culturally responsive programs to prevent opioid-related overdose deaths among this population.
- |||||||||| fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg.
Journal, Surgery: Bilateral ultrasound-guided erector spinae plane block for postoperative pain relief in major traumatic spine surgery: A randomized controlled trial. (Pubmed Central) - Aug 16, 2024
VAS scores at rest and movement at 0, 3, 6, 9, 12, 18, and 24 hours were significantly lower (P value = 0.05) in the ESPB group compared with the control group at all time points. Bilateral ultrasound-guided Erector spinae plane block, when administered in traumatic spine patients undergoing spine fixation surgery, provides better analgesia with statistically decreased VAS scores and less postoperative opioid requirement.
- |||||||||| Olinvyk (oliceridine) / Trevena
Journal: Activation of ? receptors by SR-17018 through a distinctive mechanism. (Pubmed Central) - Aug 15, 2024
Integrating these data with more traditional epidemiologic surveillance approaches has the potential to inform community overdose response efforts. Limiting receptor availability by prior exposure to ?-FNA (100
- |||||||||| fentanyl citrate / Generic mfg., sevoflurane / Generic mfg.
Retrospective data, Journal, Machine learning: Machine learning-based identification of the risk factors for postoperative nausea and vomiting in adults. (Pubmed Central) - Aug 15, 2024
Intraoperative total blood loss was identified as the potential risk factor most strongly associated with PONV, although it may correlate with duration of surgery, and insufficient circulating blood volume. The use of sevoflurane and fentanyl and the anesthesia time were not identified as risk factors for PONV in this study.
- |||||||||| fentanyl citrate / Generic mfg.
Journal: The quantitative and qualitative analysis of dye in fentanyl tablets via ultraviolet-visible spectroscopy-A forensic approach. (Pubmed Central) - Aug 13, 2024
The concentration of dye in individual tablets within a seizure proved to be very minimal, and the small sample size made it difficult to draw linkages from case to case. Analysis of the dyes could not effectively differentiate between the drug trafficking organizations in the tested population due to each DTO using the same dye; however, it is important to note that the dye found was consistent between illicit tablets.
- |||||||||| fentanyl citrate / Generic mfg., methamphetamine / Generic mfg.
Journal: Harm Reduction and Treatment Among People at High Risk of Overdose. (Pubmed Central) - Aug 12, 2024
Adults who used cocaine, methamphetamine, or opioids in the past 30 days called a study hotline and completed an interview in English or Spanish...Recent use of any harm reduction services, fentanyl test strips, naloxone possession, treatment, and self-reported barriers to services...In this cross-sectional study of people who used drugs in the past 30 days, findings highlighted low use of harm reduction and treatment services among people who use stimulants. Additional communication regarding their importance may help increase the use of the services amidst a rapidly changing drug supply.
- |||||||||| fentanyl citrate / Generic mfg.
Journal: Prevalence of fentanyl in the pediatric postmortem population from 2019 to 2023. (Pubmed Central) - Aug 12, 2024
This report contrasts the differences in postmortem pediatric fentanyl toxicology results for three groups of case histories: likely medical intervention (n?=?113), pregnancy/birth related (n?=?136), and inadvertent/intentional exposure (n?=?196). Overall, this study provides a retrospective review of postmortem pediatric fentanyl concentrations in a variety of biological matrices and highlights the need for comprehensive toxicology testing in postmortem pediatric casework.
- |||||||||| fentanyl citrate / Generic mfg., rocuronium / Generic mfg.
Journal: Stability and compatibility of an intramuscular fetal anesthetic cocktail for fetal intervention. (Pubmed Central) - Aug 11, 2024
Overall, this study provides a retrospective review of postmortem pediatric fentanyl concentrations in a variety of biological matrices and highlights the need for comprehensive toxicology testing in postmortem pediatric casework. The combination of rocuronium, fentanyl, and atropine for intramuscular fetal administration is physically compatible and chemically stable for 6 h.
- |||||||||| hydromorphone hydrochloride / Generic mfg.
Clinical, Retrospective data, Review, Journal: Efficacy and safety of hydromorphone for cancer pain: a systematic review and meta-analysis. (Pubmed Central) - Aug 10, 2024
These findings are consistent with prior comprehensive analyses, suggesting that hydromorphone is a feasible choice for alleviating cancer-associated pain. Additional investigations are warranted to determine its efficacy in distinct patient cohorts and for different modes of administration.
- |||||||||| fentanyl citrate / Generic mfg.
Observational data, Retrospective data, Journal: Effectiveness and Safety of Sublingual Fentanyl in the Treatment of (Pubmed Central) - Aug 8, 2024
The onset of analgesia was significantly more rapid for half of the patients ?75?years, compared with 65-69 and 70-74 age groups. SFC appears then to be effective, well-tolerated, and safe to treat BtCP in older cancer patients.
- |||||||||| fentanyl citrate / Generic mfg.
Journal: Reconsidering the usefulness of long-term high-dose buprenorphine. (Pubmed Central) - Aug 8, 2024
While the package insert of the combination product buprenorphinenaloxone continues to recommend a maximum dose of 16 mg daily for maintenance, the emergence of fentanyl and synthetic analogs in the current drug supply may be limiting the effectiveness of this standard dose...Some patients' path of recovery may never reach this stabilization phase (i.e., several months of adherence to medications, opioid abstinence, and other clinical indicators of stability). Side effects of buprenorphine may not have much salience when patients are struggling for survival and safety, but for those who are fortunate enough to advance in their recovery, the side effects become more problematic and can limit quality of life and adherence.
- |||||||||| naloxone injection / Generic mfg., fentanyl citrate / Generic mfg.
Journal: Missouri's overdose field report: descriptive analysis, survival trends, and naloxone dosing patterns from a community-based survey tool, 2018-2022. (Pubmed Central) - Aug 7, 2024
Our reporting form provides a comprehensive picture of the events surrounding reported overdoses, including factors associated with survival, how much naloxone was used, and the effects of respondents believing fentanyl was involved. Missouri's report can provide support for current naloxone dosing, contextualize refusing post-overdose transport, and can be used to improve overdose response by community and first responders.
- |||||||||| fentanyl citrate / Generic mfg., morphine sulphate / Generic mfg.
Journal: Isobutyryl-carfentanyl has strong acute toxicity and analgesic effects with high addiction potential. (Pubmed Central) - Aug 7, 2024
Overnight exposure of co-cultures to 100 nM fentanyl severely reduced the proportion of MSNs with spontaneous action potentials, which was unaffected by co-exposure to the opioid receptor antagonist naloxone (10 In summary, isobutyryl-carfentanyl has high acute toxicity and analgesic effect, with strong psychological dependence approximately 5 times that of fentanyl and 0.5 times that of carfentanyl, and has extremely high abuse potency.
- |||||||||| fentanyl citrate / Generic mfg., lignocaine / Generic mfg.
Journal, Intubation: Comparison of the Magnesium Sulphate With Paracetamol Combination vs the Fentanyl With Lignocaine Combination in Attenuating the Hemodynamic Response During Laryngoscopy and Intubation: A Prospective, Double-Blinded Randomized Controlled Study. (Pubmed Central) - Aug 7, 2024
The percentage change from baseline at one-minute post-induction was 3.3 in Group A and 2.8 in Group B. The percentage change from baseline was found to be within 15%, for HR in Group A and for systolic blood pressure (SBP), diastolic blood pressure (DBP), and MAP in Group B. However, there was no statistically significant difference (p > 0.05) between the mean HR, SBP, DBP, and MAP between the time points. Conclusion In our study, both the combinations of drugs, magnesium sulphate with paracetamol (Group A drugs) and fentanyl with lignocaine (Group B drugs) were found to be equally effective (i.e. neither group was superior to the other) in attenuating the hemodynamic response to laryngoscopy and intubation.
- |||||||||| ondansetron / Generic mfg.
A Cautionary Tale: Polypharmacy and the Zofran Dilemma (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5849;
Suspecting opioid-induced respiratory depression compounded by Zofran, naloxone was administered, improving his condition. Monitoring and supportive care ensued until respiratory stability and full consciousness was regained.
- |||||||||| fentanyl citrate / Generic mfg.
Differential Diagnosis of Paediatric Laryngospasm on Induction: Think Fast (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5637;
IV Propofol 80 mg, Fentanyl 15 mcg were administered...She was transported intubated to CT scan which revealed an asymmetric, 4.9 x 2.3 x 4.6cm retropharyngeal mass with regional mass effect. Patient was extubated in PICU uneventfully and scheduled for confirmed lipoma excision one week later.
- |||||||||| Hip Replacement Surgery in a Patient with Recent STEMI: a Case Report (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5287;
Her oxygenation then improved to 100%SpO2 and she was extubated smoothly. Anesthetic management consisted of general anesthesia with fentanyl,midazolam,rocuronium, and sevoflurane.A central line and radial arterial line with FloTrac
- |||||||||| fentanyl citrate / Generic mfg., hydroxyzine hydrochloride / Generic mfg., sevoflurane / Generic mfg.
Naloxone-induced restlessness after general anesthesia: a case report (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5245;
A 67-year-old woman underwent thyroidectomy due to thyroid cancer under general anesthesia using sevoflurane and fentanyl. Several minutes after, she complained restlessness and couldn
- |||||||||| fentanyl citrate / Generic mfg.
(Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5229;
Catheter infusion of 0.0625% bupivacaine with 2 ?g/mL fentanyl started at reduced rate...Finally, with a third dose, adequate T4 blockade allowed safe delivery. Catheter positioning issues likely resulted from improper placement or catheter malfunctions, underscoring the importance of meticulous technique in epidural anesthesia.
- |||||||||| fentanyl citrate / Generic mfg., enoxaparin sodium / Generic mfg.
Management of a Parturient with Severe SLE and its High-Risk Sequelae (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5217;
She subsequently is on dialysis and has CHF with moderate mitral regurgitation, recurrent right IJ DVT on Enoxaparin, and chronic back pain s/p spinal cord stimulator. After multidisciplinary planning, the patient had an uncomplicated vaginal delivery with labor analgesia of inhaled nitrous oxide, IV fentanyl PCA, and strict fluid management.
- |||||||||| fentanyl citrate / Generic mfg., ropivacaine / Generic mfg.
Unilateral Horner Syndrome After Lumbar Epidural Anesthesia for Labor and Delivery (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5214;
One hour after catheter placement and ropivacaine and fentanyl infusion, patient presented unilateral Left sided facial ptosis, miosis, dose dependent, which resolved minutes after catheter removal. The patient underwent delivery the same day without complications or sequelae for her or her baby.
- |||||||||| Opportune Perioperative Management of a Patient with Multiple Allergies (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5112;
Before her third attempt, prednisone, cetirizine, and famotidine were started one week before surgery as additional premedication. Following uneventful inhalation induction and total thyroidectomy, test doses of acetaminophen, propofol, and fentanyl were given without incident to provide the patient with an anesthetic pharmaceutical profile in the event of future surgeries.
- |||||||||| fentanyl citrate / Generic mfg.
Anesthetic Management of Neonate with Coarctation of Aorta and Possible Family History of Malignant Hyperthermia (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5062;
Anesthetic plan was transitioned from primary-inhalational anesthetic to fentanyl-TIVA consequently. Discussion points of this case include proper evaluation of family history of MH, if anesthetic management should change given limited and/or improbable family history of MH, and optimal induction and maintenance strategies of MH-susceptible cardiac-comorbid neonates.
- |||||||||| fentanyl citrate / Generic mfg.
Fifth Cardiac Surgery for Noncompliant Shone (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_4933;
There were brief periods of instability, but overall, she tolerated the procedure well. She was extubated, transferred to PACU, and discharged home on post-op day 2.
- |||||||||| dexmedetomidine / Generic mfg.
Dexmedetomidine to Potentiate Epidural Analgesia During the Second Stage of Labor: A Case Report (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_4836;
We present utility in dexmedetomidine (DXM) to enhance sacral analgesia without motor impairment.Case Description: 28-year-old G4P2 in labor received lumbar LEA with ropivacaine/fentanyl. During the second stage, patient developed uncontrolled groin pain, which was relieved after administering 2
- |||||||||| fentanyl citrate / Generic mfg., dexmedetomidine / Generic mfg.
Using intrathecal dexmedetomidine instead of fentanyl in spinal anesthesia for cesarean delivery: 2 case reports (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_4826;
These cases support the use of Dexmedetomidine (DXM) as a substitute for fentanyl as it demonstrated rapid onset of anesthesia, dense blockade, and avoided conversion to general anesthesia. Possible benefits of DXM as an adjuvant for anesthesia include faster onset, denser blockade, and longer duration.3 Use of DXM may also reduce risks of pruritus, respiratory depression, and addiction.
- |||||||||| fentanyl citrate / Generic mfg., buprenorphine/naloxone sublingual film / Generic mfg.
Anesthetic Implications of Polysubstance Street Drug Abuse and Dependency in Parturients (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_4824;
The newborn was born with an Apgar score of 7 and admitted to the NICU for neonatal abstinence syndrome. The mother remained in the hospital for opioid tapering and Suboxone initiation however left AMA.
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