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39 Diseases |  |
5 Trials |
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5 Trials |  |
18506 News |  |
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- | Trial termination: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Jul 27, 2018
P2, N=33, Terminated, Sponsor: Wake Forest University Health Sciences
Suspended --> Terminated
- | fentanyl buccal / Generic mfg.
Clinical, Journal: Effect of Prophylactic Fentanyl Buccal Tablet on Episodic Exertional Dyspnea: A Pilot Double-Blind Randomized Controlled Trial. (Pubmed Central) - Jul 5, 2018
This study supports that prophylactic FBT was associated with a reduction of exertional dyspnea and was well tolerated. Our findings support the need for larger trials to confirm the therapeutic potential of rapid-onset opioids.
- | Trial completion date, Trial primary completion date, Surgery: Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery (clinicaltrials.gov) - Mar 29, 2018
P=N/A, N=50, Recruiting, Sponsor: University of Pennsylvania
Our findings support the need for larger trials to confirm the therapeutic potential of rapid-onset opioids. Trial completion date: Nov 2018 --> May 2019 | Trial primary completion date: Feb 2018 --> Nov 2018
- | Vycavert (10 mg hydrocodone bitartrate/325 mg acetaminophen) / Acura Pharma, 3-day fentanyl transdermal patcht / Generic mfg.
Clinical, Journal, HEOR: Self-reported prevalence, description and management of pain in adults with haemophilia: methods, demographics and results from the Pain, Functional Impairment, and Quality of life (P-FiQ) study. (Pubmed Central) - Mar 21, 2018
Patients with chronic pain, particularly those with both acute/chronic pain, frequently experience psychological issues, functional disability and reduced HRQoL. Treatment strategies for acute pain (e.g. routine infusions to prevent bleeding) and for chronic pain (e.g. long-acting opioids) may be underused.
- | fentanyl citrate / Generic mfg., 3-day fentanyl transdermal patcht / Generic mfg., fentanyl buccal / Generic mfg.
Enrollment open: Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia (clinicaltrials.gov) - Mar 9, 2018
P2/3, N=105, Recruiting, Sponsor: Loyola University
Treatment strategies for acute pain (e.g. routine infusions to prevent bleeding) and for chronic pain (e.g. long-acting opioids) may be underused. Not yet recruiting --> Recruiting
- | Trial primary completion date: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Jan 26, 2018
P2, N=40, Suspended, Sponsor: Wake Forest University Health Sciences
Not yet recruiting --> Recruiting Trial primary completion date: Feb 2018 --> Aug 2018
- | fentanyl citrate / Generic mfg., 3-day fentanyl transdermal patcht / Generic mfg., fentanyl buccal / Generic mfg.
Trial initiation date: Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia (clinicaltrials.gov) - Jan 11, 2018
P2/3, N=105, Not yet recruiting, Sponsor: Loyola University
Trial primary completion date: Feb 2018 --> Aug 2018 Initiation date: Jul 2017 --> Jan 2018
- | 3-day fentanyl transdermal patcht / Generic mfg.
Clinical, Journal: The Opioid Rotation Ratio from Transdermal Fentanyl to "Strong" Opioids in Patients with Cancer Pain. (Pubmed Central) - Dec 23, 2017
Initiation date: Jul 2017 --> Jan 2018 The median ORR from TDF mg/day to MEDD is 100 and from TDF mcg/hour to MEDD is 2.4, suggesting that TDF 100 mcg/hour is equivalent to an MEDD of 240 mg.
- | Lazanda (fentanyl) / Assertio, Kyowa Hakko Kirin
Clinical, Journal: Impact of Prophylactic Fentanyl Pectin Nasal Spray on Exercise-Induced Episodic Dyspnea in Cancer Patients: A Double-Blind, Randomized Controlled Trial. (Pubmed Central) - Dec 23, 2017
P2
FPNS was safe, reduced dyspnea at rest, and increased walk distance in before-after comparison. The placebo effect was substantial, which needs to be factored in future study designs.
- | Trial primary completion date, Surgery: Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery (clinicaltrials.gov) - Nov 14, 2017
P=N/A, N=50, Recruiting, Sponsor: University of Pennsylvania
The placebo effect was substantial, which needs to be factored in future study designs. Trial primary completion date: Sep 2017 --> Feb 2018
- | fentanyl citrate / Generic mfg.
Journal: Nebulized Fentanyl for Dyspnea in a Hospice Patient with True Allergy to Morphine and Hydromorphone. (Pubmed Central) - Sep 21, 2017
However, the patient had a true morphine and hydromorphone allergy. She was administered nebulized fentanyl for symptomatic relief of dyspnea with good effect and she did not experience any allergic response.
- | fentanyl citrate / Generic mfg.
Journal: A comparison of 3 ventilation strategies in children younger than 1 year using a Proseal laryngeal mask airway: a randomized controlled trial. (Pubmed Central) - Sep 3, 2017
All 3 modes of ventilation using a PLMA were safe in children younger than 1 year. Although we did not observe a statistically significant increase in etco2, differences in TV and RR, and the small but significant incidence of apnea may make PSV or PCV more optimal ventilation strategies in children younger than 1 year when using a PLMA.
- | Instanyl (fentanyl) / Takeda
Journal: Intranasal fentanyl for initial treatment of vaso-occlusive crisis in sickle cell disease. (Pubmed Central) - Sep 2, 2017
Children who received INF had a greater decrease in pain score at 20 min compared to those who received placebo. Further studies should evaluate how to best incorporate INF into the emergency care of a child with a VOC.
- | fentanyl citrate / Generic mfg.
New trial: Cerebral Prophylactic Irradiation With Saving Hippocampus and Amygdala (clinicaltrials.gov) - Jul 5, 2017
P=N/A, N=20, Recruiting, Sponsor: Centre Francois Baclesse, Luxembourg
- | Phase classification: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - May 30, 2017
P2, N=40, Suspended, Sponsor: Wake Forest University Health Sciences
Further studies should evaluate how to best incorporate INF into the emergency care of a child with a VOC. Phase classification: P=N/A --> P2
- | fentanyl citrate / Generic mfg., 3-day fentanyl transdermal patcht / Generic mfg., fentanyl buccal / Generic mfg.
Trial initiation date, Trial primary completion date: Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia (clinicaltrials.gov) - Apr 28, 2017
P2/3, N=105, Not yet recruiting, Sponsor: Loyola University
Phase classification: P=N/A --> P2 Initiation date: Jul 2013 --> Jul 2017 | Trial primary completion date: Jul 2018 --> Jul 2020
- | Trial primary completion date: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Mar 14, 2017
P=N/A, N=40, Suspended, Sponsor: Wake Forest University Health Sciences
Initiation date: Jul 2013 --> Jul 2017 | Trial primary completion date: Jul 2018 --> Jul 2020 Trial primary completion date: Feb 2017 --> Feb 2018
- | fentanyl citrate / Generic mfg., Subsys (fentanyl sublingual spray) / Insys Therap, 3-day fentanyl transdermal patcht / Generic mfg.
Journal: Fentanyl sublingual spray for breakthrough cancer pain in patients receiving transdermal fentanyl. (Pubmed Central) - Mar 1, 2017
P3
FSS can be safely titrated to an effective dose for BTCP in patients receiving ATC TFP as chronic cancer pain medication. ClinicalTrials.gov identifier: NCT00538850.
- New trial, Surgery: Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery (clinicaltrials.gov) - Nov 20, 2016
P=N/A, N=50, Recruiting, Sponsor: University of Pennsylvania
- dexmedetomidine / Generic mfg.
Surgery: Dexmedetomidine and Desflurane Consumption (clinicaltrials.gov) - Nov 10, 2016
P=N/A, N=40, Completed, Sponsor: Theodor Bilharz Research Institute
ClinicalTrials.gov identifier: NCT00538850. Recruiting --> Completed | Trial primary completion date: Feb 2017 --> Oct 2016
- dexmedetomidine / Generic mfg.
Surgery: Dexmedetomidine and Desflurane Consumption (clinicaltrials.gov) - Nov 1, 2016
P=N/A, N=40, Recruiting, Sponsor: Theodor Bilharz Research Institute
Recruiting --> Completed | Trial primary completion date: Feb 2017 --> Oct 2016 Not yet recruiting --> Recruiting | Trial primary completion date: Jun 2017 --> Feb 2017
- fentanyl citrate / Generic mfg.
New trial: Effect of Product Related Factors on Platelet Concentrate Transfusion Response in Patients With Hematologic Malignacies (clinicaltrials.gov) - Aug 31, 2016
P=N/A, N=1101, Completed, Sponsor: Etablissement Fran
- | fentanyl citrate / Generic mfg., 3-day fentanyl transdermal patcht / Generic mfg.
Trial completion, Trial primary completion date: Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women (clinicaltrials.gov) - May 12, 2016
P3, N=105, Completed, Sponsor: Lawson Health Research Institute
Not yet recruiting --> Recruiting | Trial primary completion date: Jun 2017 --> Feb 2017 Not yet recruiting --> Completed | Trial primary completion date: Apr 2014 --> Oct 2014
- Trial suspension: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Apr 28, 2016
P=N/A, N=40, Suspended, Sponsor: Comprehensive Cancer Center of Wake Forest University
Not yet recruiting --> Completed | Trial primary completion date: Apr 2014 --> Oct 2014 Recruiting --> Suspended
- Trial primary completion date: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Feb 11, 2016
P=N/A, N=40, Recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
Recruiting --> Suspended Trial primary completion date: Jan 2016 --> Feb 2017
- dexmedetomidine / Generic mfg.
Surgery: Dexmedetomidine and Desflurane Consumption (clinicaltrials.gov) - Jan 11, 2016
P=N/A, N=40, Not yet recruiting, Sponsor: Theodor Bilharz Research Institute
- Trial primary completion date: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=40, Recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
Trial primary completion date: Jan 2016 --> Feb 2017 Trial primary completion date: Jul 2015 --> Jan 2016
- || fentanyl citrate / Generic mfg., 3-day fentanyl transdermal patcht / Generic mfg., fentanyl buccal / Generic mfg.
New P2/3 trial: Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia (clinicaltrials.gov) - Jul 2, 2015
P2/3, N=105, Recruiting, Sponsor: Loyola University
- dexmedetomidine / Generic mfg.
Clinical: Safety of Dexmedetomidine in Severe Traumatic Brain Injury (clinicaltrials.gov) - May 27, 2015
P2, N=0, Withdrawn, Sponsor: University of Maryland
Trial primary completion date: Jul 2015 --> Jan 2016 N=40 --> 0
- Trial primary completion date: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Feb 3, 2015
P=N/A, N=40, Recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
N=40 --> 0 Trial primary completion date: Jan 2015 --> Jul 2015
- Subsys (fentanyl sublingual spray) / Insys Therap
Enrollment change, Trial termination: An Observational, Non-Interventional Trial to Assess Patient Satisfaction and Safety of Subsys (clinicaltrials.gov) - Sep 5, 2014
P=N/A, N=4, Terminated, Sponsor: International Clinical Research Institute
Trial primary completion date: Jan 2015 --> Jul 2015 N=100 --> 4 | Active, not recruiting --> Terminated; Enrollment was more challenging than anticipated.
- || fentanyl citrate / Generic mfg., 3-day fentanyl transdermal patcht / Generic mfg.
New P3 trial: Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women (clinicaltrials.gov) - Dec 5, 2013
P3, N=105, Not yet recruiting, Sponsor: Lawson Health Research Institute
- Subsys (fentanyl sublingual spray) / Insys Therap
Enrollment closed: An Observational, Non-Interventional Trial to Assess Patient Satisfaction and Safety of Subsys (clinicaltrials.gov) - Aug 15, 2013
P=N/A, N=100, Active, not recruiting, Sponsor: International Clinical Research Institute
N=100 --> 4 | Active, not recruiting --> Terminated; Enrollment was more challenging than anticipated. Recruiting --> Active, not recruiting
- fentanyl citrate / Generic mfg.
New P1 trial: Pharmacokinetic Study of Fentanyl 400 (clinicaltrials.gov) - Jan 29, 2013
P1, N=40, Completed, Sponsor: Insys Therapeutics Inc
- | Rapinyl (fentanyl) / Kyowa Kirin, Orexo, Zydus Cadila
Clinical: Alternative Sedation During Bronchoscopy (clinicaltrials.gov) - Jan 13, 2013
P4, N=50, Completed, Sponsor: University of Pennsylvania
Recruiting --> Active, not recruiting Recruiting --> Completed
- ketamine / Generic mfg.
Trial withdrawal: Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients (clinicaltrials.gov) - May 31, 2012
P=N/A, N=0, Withdrawn, Sponsor: University of Utah
Recruiting --> Completed Not yet recruiting --> Withdrawn
- ketamine / Generic mfg.
Enrollment change: Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients (clinicaltrials.gov) - May 31, 2012
P=N/A, N=0, Withdrawn, Sponsor: University of Utah
Not yet recruiting --> Withdrawn N=150 --> 0
- Emla-cream / Akorn, AstraZeneca
Enrollment change: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Mar 8, 2012
P=N/A, N=40, Recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
N=150 --> 0 N=20 --> 40
- Emla-cream / Akorn, AstraZeneca
Enrollment open: Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) - Feb 14, 2012
P=N/A, N=40, Recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
N=20 --> 40 Not yet recruiting --> Recruiting