fentanyl citrate / Generic mfg. 
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  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Fentanyl depression of respiration: comparison with heroin and morphine. (Pubmed Central) -  Sep 10, 2019   
    We propose that several factors (potency, rate of onset, lowered sensitivity to naloxone and lowered cross tolerance to heroin) combine to make fentanyl more likely to cause opioid overdose deaths than other commonly abused opioids. Lipophilic antagonists such as diprenorphine may be better antidotes than naloxone to treat fentanyl overdose.
  • ||||||||||  Duragesic (fentanyl) / J&J
    Pacemaker-mediated-tachycardia – case report. () -  Sep 10, 2019 - Abstract #EUSEM2019EUSEM_1469;    
    We practiced biphasic synchronous cardioversion with 70J SEE under the anesthetic induction sequence (fentanyl and midazolam) that stopped stimulating and restored sinusal rythm...The educational issue and clinical relevance of the case is related to: - Recognition of the mechanism of producing of the rhythm disturbance (repetitive atrioventricular retrograde conduction, in a ICD carrier, can generate pacemaker-mediated-tachycardia or VA synchrony when the pacemaker detects retrograde P-wave), is not always easy for the young emergency doctors - The limited possibilities of arrhythmia interruption, in a hemodynamic unstable patient, in the pre-hospital environment. If cardioversion is opted for, it is a priori admited device magnetization and future pacemaker malfunction and, therefore, the necessity of his compulsory reprogramming - The usual medication is not an option when pacemaker-mediated-tachycardia, but medication-induced depression of inotropism may become a precipitating factor of left ventricular insufficiency - Emergency dispatchers and telemedicine reception centers should require field crews, to transmit the ECG to be interpreted by an emergency department consultant in case of rhythm disturbances occuring to ICD carriers.
  • ||||||||||  quetiapine / Generic Mfg.
    Cord transection as a rare cause of respiratory failure in a drowsy patient with Parkinson's disease. () -  Sep 10, 2019 - Abstract #EUSEM2019EUSEM_1343;    
    Post-intubation a fentanyl infusion (35mcg/hour) was started...Additional questioning revealed his mentioning physical abuse by the carer but he had also started Quetiapine for hallucinations at that time...This case highlights a) the need for vigilance for signs of trauma with even fading bruises taken seriously and spinal precautions taken, b) the prudence of spinal precautions when drowsiness limits ability to complete a neurological examination, and c) the need to consider non-accidental injury in the vulnerable population, especially when the signs do not match the story. Clues to watch for include bradycardia that accompanies the sudden dips in the BP, that suggest neurogenic shock as a differential to infective causes.
  • ||||||||||  Duragesic (fentanyl) / J&J
    Coma caused by multipl transdermal fentanyl application. () -  Sep 10, 2019 - Abstract #EUSEM2019EUSEM_1334;    
    An 78 year-old white male with lung cancer was admitted to emergency service with eight 100 mg/h fentanyl patches on his backchest. This case demonstrates the need for caution in self-administration of transdermal fentanyl patches, in particular, the dangers inherent in the application of multiple patches which can result in the release of potentially toxic, comatose and lethal doses.
  • ||||||||||  fentanyl citrate / generics
    Acute pain and weakness in one leg: unusual presentation of a ruptured abdominal aortic aneurysm. () -  Sep 10, 2019 - Abstract #EUSEM2019EUSEM_1262;    
    Due to the strong pain that the patient presented, we administered two doses of 50 mcg of Fentanyl, without any improvement and even worsening of the pain...Ruptured AAA was suspected, but it was considered unlikely due to the clinic and therefore he moved to his nearest center without vascular surgery but able to perform CT. Despite the usual presentation of ruptured aortic aneurysm is abdominal and / or back pain, other presentation may occur, so the diagnosis always requires a high suspicion.
  • ||||||||||  fentanyl citrate / generics
    MUSED: Metoxyflurane Use in Emergency Department: head to head study of metoxyflurane vs. standard of care. () -  Sep 10, 2019 - Abstract #EUSEM2019EUSEM_1047;    
    We will include 60 patients in this study, 30 of which will get metoxyflurane, and 30 who will get standard of care, which can be different depending on the operator, and includes hemathoma block, classic PSA with propofol or midazolam with fentanyl, parenteral nonstreroids, or some other medication for pain management...During the aplication od metoxyflurane or SoC we will also record side effects, and up to 30 minutes postprocedure. Primary aim of tis study is to show that metoxyflurane is not inferior to standard of care, in terms of change of NRS pain intensity at any moment after the medication application.
  • ||||||||||  fentanyl citrate / generics
    Ultra-sound guided femoral nerve block for pain mangement in femur fractures in the emergency department. () -  Sep 10, 2019 - Abstract #EUSEM2019EUSEM_1004;    
    Pin prick was done every 2 hours after confirmation of successful block and duration of the block was identified as the duration between local anesthetic injection and regaining of sensation in the dermatomal distribution of the femoral nerve,Fentanyl consumption , Adverse effects , Patients satisfaction. Results : ultrasound guided femoral nerve block (FNB) improved the analgesic regimen in patients admitted to the emergency department (ED) with femur fractures, when added to the standard multimodal analgesic protocol conclusion : ultrasound (US) guided femoral nerve block (FNB) by emergency physician was safe, rapid, effective, and long lasting option when added to standard analgesia in patients with femur fractures in the emergency department.
  • ||||||||||  fentanyl citrate / generics
    Are men and women treated equally when presenting with a renal colic? () -  Sep 10, 2019 - Abstract #EUSEM2019EUSEM_820;    
    Intercurrent urinary tract infection is more frequently found in women, leading to higher CRP levels and a justified increase in the use of antibiotics and urinary antiseptics. Previous studies showed similar results.
  • ||||||||||  fentanyl citrate / generics
    The Characteristics of Out-Patient Use of Intravenous Milrinone in the United States () -  Sep 9, 2019 - Abstract #HFSA2019HFSA_235;    
    There is geographic variability in the use of home milrinone, and the patients receiving it are relatively young. While some use of home milrinone appears to be as a bridge to advanced heart failure treatment, much appears to be related to end of life care.
  • ||||||||||  fentanyl citrate / generics
    Clinical, Journal:  Not all pains are the same: breakthrough pain in cancer patients. A case report (Pubmed Central) -  Sep 8, 2019   
    Some fentanyl formulations represent a good option to handle this symptom. We report the case of one of our patients where early integration of palliative care service consented an optimal management of cancer pain.
  • ||||||||||  Duragesic (fentanyl) / J&J
    Journal:  Palliative Care Development in Kyrgyzstan. (Pubmed Central) -  Sep 7, 2019   
    Today palliative care is included in many national health care policies and laws, a national palliative care association has been established, undergraduate medical and nursing education include elements of palliative care, oral morphine and fentanyl patches are now available in parts of the country, inpatient services exist in the National Cancer Center in Osh and Bishkek, two TB hospitals with MDR/XDR, and home care services in Osh and Bishkek. Public information campaigns and advocacy activities continue to increase public awareness about palliative care and press government action.
  • ||||||||||  fentanyl citrate / generics, ketamine / generics
    Journal:  A Novel Rat Model of Extremity Trauma for Pre-hospital Pain Management Research. (Pubmed Central) -  Sep 7, 2019   
    Our model produces acute, steady, and reproducible trauma-related pain behaviors, and is clinically relevant regarding the pain behaviors and established responses to common analgesics. This model of acute pain due to ET is ideal for pre-hospital pain management research.
  • ||||||||||  carbamazepine / Generic Mfg.
    Journal:  Prolonged therapy with the anticonvulsant carbamazepine leads to increased plasma clearance of fentanyl. (Pubmed Central) -  Sep 6, 2019   
    Chronic carbamazepine therapy leads to increased fentanyl clearance and decreased AUC, which may result in decreased duration of therapeutic plasma concentrations of fentanyl and an increased dose requirement. Assuming that carbamazepine does not change fentanyl pharmacodynamics, patients on chronic carbamazepine therapy may require more frequent or higher fentanyl doses to maintain therapeutic plasma concentrations.
  • ||||||||||  Trial completion:  Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures (clinicaltrials.gov) -  Sep 6, 2019   
    P2,  N=33, Completed, 
    The findings of this study should facilitate the identification and classification of new OR ligands with fentanyl-like structures. Terminated --> Completed
  • ||||||||||  Ultane (sevoflurane) / Generic Mfg.
    Journal:  MULTIMODAL LOW-OPIOID ANESTHESIA - A NEW APPROACH TO THE ISSUE OF ADEQUATE INTRAOPERATIVE ANALGESIA. (Pubmed Central) -  Sep 3, 2019   
    The average dose of fentanyl, which was used for the entire period of anesthesiology support was 1,09±0.03 μg/kg/h (358,3±27,1 μg for the duration of surgery). As a result of the carried-out researches it was established, that multimodal low-opioid anesthesia, provides an adequate analgesic effect, and allows to refuse from intraoperative application of high doses of narcotic analgesics in the performance of highly traumatic operations, which is confirmed by the lack of hemodynamic and endocrine-metabolic shifts in its use.
  • ||||||||||  fentanyl citrate / generics
    Clinical, Journal:  Retrograde Intrathecal Drug Delivery: A Report of Three Cases for the Management of Cancer-Related Sacropelvic Pain. (Pubmed Central) -  Sep 1, 2019   
    Improving linkage to and engagement in risk-reduction services and evidence-based treatment for persons with opioid and other substance use disorders with attention to polysubstance use or misuse is also needed. We report three cases of sacral and pelvic pain resistant to oral medications successfully managed with intraspinal drug delivery through a catheter placed at the intrathecal sacral space to deliver low doses of bupivacaine and fentanyl with local effects.
  • ||||||||||  fentanyl citrate / generics, lorazepam / generics
    Clinical, Journal:  Sedation and analgesia in patients on mechanical ventilation in pediatric intensive care units in Argentina. (Pubmed Central) -  Aug 30, 2019   
    We report three cases of sacral and pelvic pain resistant to oral medications successfully managed with intraspinal drug delivery through a catheter placed at the intrathecal sacral space to deliver low doses of bupivacaine and fentanyl with local effects. Only a low percentage of surveyed PICUs had a protocol in place for the routine management of sedation and analgesia in patients on MV.
  • ||||||||||  fentanyl citrate / generics
    Journal:  Mass Spectral Character of Fentanyl Analogues. (Pubmed Central) -  Aug 30, 2019   
    While in the EI mode, dissociation of the piperidine ring, as well as cleavage between the piperidine ring and the phenethyl were the main fragmentation pathways. Conclusion This study summarizes the main fragmentation pathways and characteristic ions of fentanyl analogues in the CID and EI modes, which is useful for forensic laboratories to identify and structural analyze fentanyl type new psychoactive substance in practical work.
  • ||||||||||  fentanyl citrate / generics
    Journal:  Pre-induction fentanyl dose-finding study for controlled hypotension during functional endoscopic sinus surgery. (Pubmed Central) -  Aug 30, 2019   
    Surgical field conditions and surgeon satisfaction scores were significantly superior in fentanyl 3 μg/kg and 4 μg/kg groups than in fentanyl 2 μg/kg group. Pre-induction fentanyl 3 μg/kg and 4 μg/kg group showed superior controlled hypotension facilitation than 2 μg/kg fentanyl during FESS in terms of measurable haemodynamic endpoints and favourable operative conditions, surgeon's satisfaction and sparing of additional hypotensive agents.