fentanyl citrate / Generic mfg. 
Welcome,         Profile    Billing    Logout  
 39 Diseases   5 Trials   5 Trials   18506 News 


«12...184185186187188189190191192193194...222223»
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Journal:  Safety of a Modified Community Trailer to Manage Patients with Presumed Fentanyl Overdose. (Pubmed Central) -  Jul 4, 2020   
    We treated 269 patients with opioid OD, transferred three (1.1%) to a local ED, started 43 (16.0%) on opioid agonists, and provided 220 (81.7%) with THN. Our program appears to be safe and may serve as a model for other settings dealing with a large numbers of opioid OD.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal, HEOR:  Health Care Utilization of Opioid Overdose Decedents with No Opioid Analgesic Prescription History. (Pubmed Central) -  Jul 4, 2020   
    Decedents who did not fill an opioid prescription were less likely to die of an overdose involving prescribed opioids (7.3% vs 19.5%, p < .001) and more likely to fatally overdose on heroin (63% vs 50.4%, p < .001) or fentanyl/fentanyl analogues (50.3% vs 41.8%, p = .001)...We identified a subset of individuals in Illinois who may not be impacted by such interventions. Additional research is needed to understand what strategies may be successful among high-risk populations that have limited opioid analgesic prescription history and low health care utilization.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Retrospective data, Journal:  A retrospective analysis of the epidural use of bupivacaine 0.0625-0.125% with opioids in bitches undergoing cesarean section. (Pubmed Central) -  Jul 4, 2020   
    Cases of dogs undergoing cesarean section that were anesthetized without epidural (n = 29) (control) and dogs with low-dose epidural bupivacaine with fentanyl or buprenorphine (n = 37) were reviewed...Intraoperative opioids were administered more to control (93%) than to treated dogs (18%; P < 0.0001). Epidural bupivacaine 0.0625-0.125% combined with an opioid reduced the use of intraoperative opioids and did not exacerbate arterial hypotension during cesarean section in anesthetized dogs.
  • ||||||||||  fentanyl citrate / Generic mfg., Analgin (metamizole) / Sedico
    Clinical, Journal:  Drug prescription patterns in osteoarthris patients in a tertiary care hospital in China. (Pubmed Central) -  Jul 3, 2020   
    The combination-regimens could cause potential drug interactions, may impact the health of OA patients. In this study, the increment in the use of COX-2 inhibitors and opioids is substantial due to the effect on safety and prices of the medication.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Journal:  Prevalence of Cesarean Section and Analysis of Neonatal Apgar Score and the Mean Time of Second Phase of Labor in Pregnant Women. (Pubmed Central) -  Jul 3, 2020   
    Patients in the labor epidural group underwent analgesia using marcaine and fentanyl and after fully assuring the normal hemodynamic status of the mother and fetal hearth rate (FHR), labor spinal analgesia was used for other group...Labor epidural analgesia and labor spinal analgesia result in a significant reduction in pain due to normal delivery. Due to the similarity of Apgar and arterial blood gas (ABG) in neonates, labor epidural analgesia may serve as an alternative in childbirth delivery.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  The Effect of Prophylactic Doses of Reviparin on the Postoperative Value of Platelets. (Pubmed Central) -  Jul 3, 2020   
    All patients had the same endotracheal anesthesia with Propofol, Fentanyl, and Atracurium supplemented with oxygen and nitric oxide at the appropriate dose...that patients who had higher preoperative values retained more platelet values even during postoperative measurements. Platelet values do not change significantly postoperatively with the use of prophylactic doses of Reviparin, after an open cholecystectomy.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Performing High-resolution Impedance Manometry After Endoscopy With Conscious Sedation Has Negligible Effects on Esophageal Motility Results. (Pubmed Central) -  Jul 3, 2020   
    Twelve asymptomatic adult volunteers and 7 adult patients completed high-resolution impedance manometry (HRIM) approximately 1 hour after conscious sedation with midazolam and fentanyl (post-sedation) and again on a different day with no-sedation...Performing HRIM after endoscopy with conscious sedation had minimal clinical impact on the motility diagnosis or motility parameters. Thus, this approach may be a viable alternative for patients who cannot tolerate unsedated catheter placement.
  • ||||||||||  fentanyl citrate / Generic mfg., cordycepin (OVI-123) / OncoVista
    Preclinical, Journal:  In vitro nociceptor neuroplasticity associated with in vivo opioid-induced hyperalgesia. (Pubmed Central) -  Jul 2, 2020   
    Using this model, we have found qualitative and quantitative differences between cultured nociceptors from opioid naïve and opioid primed animals, and provide evidence for the important role of nociceptor MOR-mediated calcium signaling and peripheral protein translation, in the weakly IB4-binding population of nociceptors, in OIH. These findings provide information useful for the design of therapeutic strategies to alleviate OIH, a serious adverse event of opioid analgesics.
  • ||||||||||  fentanyl citrate / Generic mfg., nalbuphine / Endo
    Retrospective data, Review, Journal:  Sex differences in the response to opioids for pain relief: A systematic review and meta-analysis. (Pubmed Central) -  Jul 2, 2020   
    However, the role of these factors is not usually evaluated in the prescription of opioids for pain control. There is an urgent need to conduct clinical trials on the use of opioid medications for pain, in which information about all possible influencing factors are provided and broken down for men and women.
  • ||||||||||  fentanyl citrate / Generic mfg., levamisole / Generic mfg.
    Journal:  Drug checking services at music festivals and events in a Canadian setting. (Pubmed Central) -  Jul 2, 2020   
    We found a large proportion of substances that contained unexpected adulterants. Our findings highlight the value of continued drug checking and will be helpful in designing future harm reduction interventions in similar contexts.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Correlates of take-home naloxone kit possession among people who use drugs in British Columbia: A cross-sectional analysis. (Pubmed Central) -  Jul 2, 2020   
    Lower kit possession among those that preferred inhaling, smoking or snorting drugs may reflect misconceptions around overdose risk of non-injection drug administration. Our study supports the need for enhanced awareness around the risk of opioid overdose with non-injection administration and suggests a need for comprehensive public health messaging that aims to address overdose risk and response.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Examining opioid-involved overdose mortality trends prior to fentanyl: New York City, 2000-2015. (Pubmed Central) -  Jul 2, 2020   
    In particular, the tamper-resistant reformulation of oxycodone 80 mg may have increased the use of heroin among primary OA users. Notably, older adults may have had established heroin use practices prior to the proliferation of OAs and thus may have been less likely to modify drug use practices.
  • ||||||||||  fentanyl citrate / Generic mfg., methadone / Generic mfg.
    Journal:  Characteristics and circumstances of heroin and pharmaceutical opioid overdose deaths: Comparison across opioids. (Pubmed Central) -  Jul 2, 2020   
    Notably, older adults may have had established heroin use practices prior to the proliferation of OAs and thus may have been less likely to modify drug use practices. Findings suggest the need to: educate PO consumers about the risks of overdose at the time of prescribing; increase coverage and engagement in opioid dependence treatment (particularly in regional/remote areas); and increase uptake of take-home naloxone to reduce opioid overdose mortality.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Atomistic Molecular Dynamics Simulations of Propofol and Fentanyl in Phosphatidylcholine Lipid Bilayers. (Pubmed Central) -  Jul 1, 2020   
    From the calculated free-energy profiles, we determined that both molecules show a preference for the low-density, low-order acyl chain region of the bilayers and both significantly preferred the DOPC bilayer with propofol and fentanyl having energy minima at -6.66 and -43.07 kcal mol, respectively. This study suggests that different chain lengths and levels of saturation directly affect the properties of these two important molecules, which are seen to work together to control anesthesia in surgical applications.
  • ||||||||||  esmolol / Generic mfg.
    Clinical, Journal:  Randomized, double-blind, placebo-controlled study of the analgesic effect of intraoperative esmolol for laparoscopic gastroplasty. (Pubmed Central) -  Jun 30, 2020   
    This study suggests that different chain lengths and levels of saturation directly affect the properties of these two important molecules, which are seen to work together to control anesthesia in surgical applications. Intraoperative esmolol promotes reductions in pain intensity and the need for analgesic supplementation without adverse effects, thus representing an effective drug for multimodal analgesia in gastroplasty.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Journal:  Opioid and Benzodiazepine Requirements in Obese Adult Patients Receiving Extracorporeal Membrane Oxygenation. (Pubmed Central) -  Jun 29, 2020   
    Fentanyl equivalents were significantly higher on day 3 in the obese group (P = 0.02) despite similar RASS scores with no differences in midazolam requirements...Conclusion and Relevance: Daily midazolam requirements were not significantly different, and opioid requirements were only significantly higher in the obese group on day 3 despite similar levels of sedation. The impact of obesity with the addition of ECMO and how to adapt doses of medications remains elusive.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Modulation of the Gloeobacter violaceus Ion Channel by Fentanyl: A Molecular Dynamics Study. (Pubmed Central) -  Jun 28, 2020   
    In this paper, we identify multiple extracellular fentanyl binding sites, which are different from the transmembrane general anesthetic binding sites observed for propofol and other general anesthetics. Our simulations identify a novel fentanyl binding site within the GLIC that results in conformational changes that inhibit conduction through the channel.
  • ||||||||||  remifentanil / Generic mfg.
    Clinical, Journal:  Remifentanil and perioperative glycaemic response in cardiac surgery: an open-label randomised trial. (Pubmed Central) -  Jun 28, 2020   
    P4
    Intraoperative use of the hypotonic solution in children causes increased FLACC scale scores, leading to higher opioid consumption in post-anesthesia care unit. Compared with patients treated with intermittent fentanyl, patients receiving continuous remifentanil infusion had fewer episodes of hyperglycaemia and less need for insulin administration during the intraoperative period of cardiac surgery.
  • ||||||||||  fentanyl citrate / Generic mfg., methadone / Generic mfg.
    Review, Journal:  The United States opioid epidemic. (Pubmed Central) -  Jun 26, 2020   
    Initially driven by increased consumption and availability of pharmaceutical opioids, an increasing number of opioid overdoses are now related to heroin and illicitly manufactured fentanyl and fentanyl analogs. Addressing this epidemic requires addressing the stigma associated with opioid use disorders and its treatment, improving access to efficacious treatment options, specifically methadone and buprenorphine, and reducing opioid overdose fatalities with distribution of the opioid antagonist and overdose reversal agent naloxone.
  • ||||||||||  fentanyl citrate / Generic mfg., ketamine / Generic mfg.
    Journal:  Factors associated with post-intubation sedation after emergency department intubation: A Report from The National Emergency Airway Registry. (Pubmed Central) -  Jun 26, 2020   
    Addressing this epidemic requires addressing the stigma associated with opioid use disorders and its treatment, improving access to efficacious treatment options, specifically methadone and buprenorphine, and reducing opioid overdose fatalities with distribution of the opioid antagonist and overdose reversal agent naloxone. Post-intubation sedation rates in NEAR are higher than previously reported and multiple factors including the indication for intubation and succinylcholine use, are associated with higher odds of receiving post-intubation sedation.
  • ||||||||||  fentanyl citrate / Generic mfg., ketamine / Generic mfg.
    Clinical, Journal:  Comparing intranasal ketamine with intravenous fentanyl in reducing pain in patients with renal colic: A double-blind randomized clinical trial. (Pubmed Central) -  Jun 26, 2020   
    Post-intubation sedation rates in NEAR are higher than previously reported and multiple factors including the indication for intubation and succinylcholine use, are associated with higher odds of receiving post-intubation sedation. Ketamine was found to be less effective than fentanyl in controlling renal colic-induced pain, and to be associated with a higher prevalence of side-effects; nevertheless, ketamine can be effective in controlling this pain in conjunction with other medications.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Journal:  Management of Opioid-Tolerant Patients with Acute Pain: Approaching the Challenges. (Pubmed Central) -  Jun 25, 2020   
    In large part, this is attributed to the growing availability of illicitly manufactured fentanyl...For some patients, perioperative care may be best coordinated by a perioperative or post-discharge service with referral to multidisciplinary pain and addiction medicine services as indicated. Carefully planned and communicated discharge prescribing, with a weaning plan for additional opioids, is essential.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Effects of Massage on Post-Operative Pain in Infants with Complex Congenital Heart Disease. (Pubmed Central) -  Jun 23, 2020   
    This study provides beginning evidence that post-operative massage may reduce pain and improve physiologic parameters in infants with congenital heart disease. This non-pharmacological adjunct to pain management may provide a particular benefit for this population by reducing demand on the cardiorespiratory system.