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39 Diseases |  |
5 Trials |
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5 Trials |  |
18506 News |  |
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- || fentanyl citrate / Generic mfg.
Clinical, Journal: Evaluation of Serratus Anterior Plane Block for Pain Relief in Patients Undergoing MIDCAB Surgery. (Pubmed Central) - Jan 26, 2021
SAP block reduced the postoperative pain scores and opioid requirements in patients undergoing MIDCAB surgery.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Influences of UGT2B7 rs7439366 and rs12233719 Polymorphisms on Fentanyl Sensitivity in Chinese Gynecologic Patients. (Pubmed Central) - Jan 26, 2021
All of the clinical features studied had no close association with rs12233719 SNP. CONCLUSIONS Gynecologic patients with rs7439366 TT genotype had significantly lower fentanyl sensitivity than the other 2 genotype carriers.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Use of acupuncture as adjuvant analgesic technique in dogs undergoing thoracolumbar hemilaminectomy. (Pubmed Central) - Jan 26, 2021
Rescue intraoperative fentanyl was administered following a 20% increase in cardiovascular parameters compared to baseline values, measured before incision...The improvement in postoperative CPS score (P = 0.013), VAS score (P = 0.003) and MT (P = 0.001) compared to preoperative values was greater for group A than for group C, whereas the treatment assignment had no effect on postoperative changes in GCPS compared to baseline. Pre-operative acupuncture may help improving perioperative analgesia in dogs with intervertebral disc herniation undergoing thoracolumbar hemilaminectomy.
- | fentanyl citrate / Generic mfg., dexamethasone / Generic mfg.
Journal: Nociception level-guided fentanyl titration: potential impact of multimodal anaesthesia and false positives. Comment on Br J Anaesth 2020; 125: 1070-8. (Pubmed Central) - Jan 26, 2021
Pre-operative acupuncture may help improving perioperative analgesia in dogs with intervertebral disc herniation undergoing thoracolumbar hemilaminectomy. No abstract available
- | fentanyl citrate / Generic mfg., remifentanil / Generic mfg.
Journal: Nociception level monitoring for personalized analgesic treatment. Response to Br J Anaesth 2020; 125: 1070-8. (Pubmed Central) - Jan 26, 2021
No abstract available No abstract available
- || fentanyl citrate / Generic mfg.
Clinical, Journal, Video: Ultrasound guided rhomboid intercostal block: A pilot study to assess its analgesic efficacy in paediatric patients undergoing video-assisted thoracoscopy surgery. (Pubmed Central) - Jan 26, 2021
Postoperative opioid consumption was also less in this group R (2.90 ± 0.91 vs 5.56 ± 1.08) (P < 0.05). Less number of patients experienced nausea (2 vs 6) and respiratory depression (2 vs 7) in group R. Ultrasound guided RIB reduces perioperative opioid consumption in patients undergoing VATS surgery with lesser postoperative pain scores.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Effect of intrathecal fentanyl on the incidence, severity, and duration of postdural puncture headache in parturients undergoing caesarean section: A randomised controlled trial. (Pubmed Central) - Jan 26, 2021
The incidence of PDPH decreased in the BF group in a non-significant manner, whereas its severity and duration increased significantly in the B0 group. Although the addition of intrathecal fentanyl to bupivacaine for SA in CS patients did not reduce the incidence of PDPH significantly, its severity and duration decreased significantly.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Ultrasound-guided Bilateral Erector Spinae Plane Block for Postoperative Analgesia in Laparoscopic Cholecystectomy: A Randomized Controlled Trial. (Pubmed Central) - Jan 26, 2021
Postoperative static and dynamic pain score as per the visual analog scale (VAS), intraoperative requirement of fentanyl, postoperative use of diclofenac, time to ambulation after surgery, and presence of any pain after surgery were noted...ESPB provides effective analgesia and early ambulation after LC. The benefit extends to 1 week thereafter.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: A Randomized Controlled Study Comparing Dexmedetomidine-Midazolam with Fentanyl-Midazolam for Sedation during awake Fiberoptic Intubation in Anticipated Difficult Airway. (Pubmed Central) - Jan 26, 2021
Fentanyl-midazolam and dexmedetomidine-midazolam are both effective for awake fiberoptic intubation under topical anesthesia. Dexmedetomidine allows better endurance and more stable hemodynamics.
- | fentanyl citrate / Generic mfg., ketamine / Generic mfg.
Journal: Cardiac Preconditioning Effect of Ketamine-Dexmedetomidine versus Fentanyl-Propofol during Arrested Heart Revascularization. (Pubmed Central) - Jan 26, 2021
As regard tracheal extubation time, patients assigned to KD group extubated earlier than whom in FP group 202.22 ± 28.674 versus 304.67 ± 40.598 min respectively P < 0.001. The use of KD during on-pump CABG confers better myocardial protective and anti-inflammatory effect than fentanyl propofol.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Evaluating Analgesic Efficacy of Single Femoral Nerve Block versus Combined Femoral-Sciatic Nerve Block Post Total Knee Arthroplasty. (Pubmed Central) - Jan 26, 2021
A total of 150 adult patients of American Society of Anesthesiologists physical status class I and II scheduled for elective TKA under spinal anesthesia with 3.4-mL bupivacaine 0.5% and 20-μg fentanyl were randomly allocated to two groups...We conclude that the FNB, when combined with SNB, shows superior results than femoral block alone. SNB reduced pain scores and opiate consumption postoperatively up to 48 h.
- || Eladur (bupivacaine) / Amneal
Clinical, Journal: Effect of Fentanyl on Block Characteristics as Adjuvant to Intrathecal Bupivacaine for Lower Limb Surgeries. (Pubmed Central) - Jan 26, 2021
However, the incidence of hypotension, nausea, and pruritus was more in Group III. 2 mg intrathecal bupivacaine with 20 μg fentanyl provides reliable and satisfactory sensory and motor block without increasing the incidence of side effects.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: The comparison of effects of fentanyl and dexmedetomidine as adjuvants to ropivacaine for ultrasound-guided transversus abdominis plane block for postoperative pain in cesarean section under spinal anesthesia -A randomized controlled trial. (Pubmed Central) - Jan 26, 2021
The amount of analgesics used in the postoperative period in both the groups were analyzed using the Chi-square test not found to have any significant difference between both the groups (P-value = 0.512). Fentanyl and dexmedetomidine as adjuvants to ropivacaine in ultrasound-guided TAP block were equally effective in both prolongation of analgesia and reducing the total consumption of analgesics.
- | fentanyl citrate / Generic mfg., isoflurane / Generic mfg.
Journal: Comparison of hemodynamic responses to laryngoscopy and intubation using Macintosh or McCoy or C-MAC laryngoscope during uniform depth of anesthesia monitored by entropy. (Pubmed Central) - Jan 26, 2021
General anesthesia was administered with glycopyrrolate 0.1 mg, fentanyl 2 ug/kg and intravenous thiopentone, 4 mg/kg...By titrating isoflurane concentration, Entropy maintained between 40 and 60, orotracheal intubation done, with Macintosh or McCoy or C-MAC blades according to simple randomisation...Hemodynamic responses during laryngoscopy and intubation using Macintosh or McCoy or C-MAC laryngoscope were statistically insignificant (p > 0.05) between the three groups, provided the depth of anesthesia is maintained constant. It is the depth of anesthesia that decides the magnitude of hemodynamic responses and not the choice of laryngoscope.
- || fentanyl citrate / Generic mfg., sevoflurane / Generic mfg.
Clinical, Journal, Video: Paravertebral Block Versus Intercostal Nerve Block in Non-Intubated Uniportal Video-Assisted Thoracoscopic Surgery: A Randomised Controlled Trial. (Pubmed Central) - Jan 23, 2021
It is the depth of anesthesia that decides the magnitude of hemodynamic responses and not the choice of laryngoscope. Regional anaesthesia by either preoperative paravertebral block or thoracoscopic intercostal nerve block with ipsilateral vagal block provided an anaesthetic sparing effect, guided by lower Ef sevo concentration, with comparable bi-spectral index in patients undergoing uniportal thoracoscopic surgery.
- || alprazolam / Generic mfg.
Clinical, Journal: Prevalence of illicit and prescribed neuropsychiatric drugs in three communities in Kentucky using wastewater-based epidemiology and Monte Carlo simulation for the estimation of associated uncertainties. (Pubmed Central) - Jan 23, 2021
Among narcotics, the per-capita consumption rate of fentanyl and morphine was significantly higher in urban communities while codeine, hydrocodone, hydromorphone, and buprenorphine were dominant in a rural community. The significantly higher prevalence of buprenorphine (˜20-30 folds), oxycodone (˜2-3 folds), and alprazolam (˜2-3 folds) determined in these communities compared to the conventional estimates based on the electronically reported prescriptions and drug-related inpatient hospitalizations suggest the abuse of these drugs.
- || ketamine / Generic mfg.
Clinical, Observational data, Journal: Clinical practice of pre-hospital analgesia: An observational study of 20,978 missions in Switzerland. (Pubmed Central) - Jan 23, 2021
Pre-hospital analgesia is mostly adequate, especially when done with ketamine or fentanyl. Female paramedics provided better analgesia and in selected patients, an emergency physician on scene improved quality of analgesia in critical patients.
- | fentanyl citrate / Generic mfg.
Journal: Effect of Timing of Intravenous Fentanyl Administration on the Incidence of Posttonsillectomy Nausea and Vomiting. (Pubmed Central) - Jan 23, 2021
Although there was no beneficial effect on PONV, recovery of regular breathing and consciousness was quicker with earlier fentanyl administration. Emergence delirium was well-controlled, similar to that with fentanyl administration at the end of surgery.
- | fentanyl citrate / Generic mfg.
Journal: A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope. (Pubmed Central) - Jan 23, 2021
A double conjugation strategy was implemented to produce an anti-fentanyl vaccine, which was predicated upon preformed-antibody-assisted antigen presentation. The new vaccine was found to reduce the psychoactive effects of fentanyl without the addition of the immunostimulant CpG oligodeoxynucleotide.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors. (Pubmed Central) - Jan 23, 2021
In summary, substituted fentanyls with high MOR potencies, selectivities, and efficacies are likely to have abuse and overdose potential. The work presented here is a prototype to investigate fentanyl derivatives and their abuse potential.
- | fentanyl citrate / Generic mfg., ketamine / Generic mfg.
Journal: Perinatal fentanyl exposure leads to long-lasting impairments in somatosensory circuit function and behavior. (Pubmed Central) - Jan 22, 2021
These findings demonstrate the lasting sequelae of perinatal fentanyl exposure on sensory processing and function.Significance Statement This is the first study to show that exposure to fentanyl in the womb results in behavioral, circuitry, and synaptic effects that last at least to adolescence. We also show, for the first time, that this exposure has different, lasting effects on synapses in different cortical areas.
- | fentanyl citrate / Generic mfg.
Journal: The Rapidly Changing US Illicit Drug Market and the Potential for an Improved Early Warning System: Evidence from Ohio Drug Crime Labs. (Pubmed Central) - Jan 21, 2021
We also show, for the first time, that this exposure has different, lasting effects on synapses in different cortical areas. Crime lab data has the potential to be used as an early warning system to alert persons who inject drugs, harm reduction services, first responders, and law enforcement about changes in the illicit opioid risk environment.
- || fentanyl citrate / Generic mfg., paracetamol / Generic mfg.
Clinical, Journal: Opioid prescriptions in patients with osteoarthritis: a population-based cohort study. (Pubmed Central) - Jan 21, 2021
Oxycodone and fentanyl were increasingly prescribed, while prescriptions of paracetamol/codeine decreased. Since the benefit of opioids for OA pain is questionable and side effects are common, opioids should be prescribed with caution.
- | Duragesic (fentanyl) / J&J
Journal: Cancer Cachexia May Hinder Pain Control When Using Fentanyl Patch. (Pubmed Central) - Jan 21, 2021
Subsequently, to investigate whether dry skin was involved in poor pain control in the cancer cachexia group, transepidermal water loss (TEWL) was compared between 15 additional patients classified into cancer cachexia and non-cancer cachexia groups; the mean TEWL in the cancer cachexia group was found to be significantly lower. Our data suggest that cancer cachexia may be a risk factor for poor pain control in patients receiving FP treatment, and that uncontrolled pain in FP treatment may be caused by the inhibition of fentanyl transdermal absorption due to dry skin.
- || fentanyl citrate / Generic mfg., lactulose / Generic mfg.
Clinical, Journal: Prevalence and management of constipation in pediatric acute lymphoblastic leukemia in U.S. children's hospitals. (Pubmed Central) - Jan 21, 2021
A large portion of hospitalized children with ALL experience constipation and required medications. Increased attention should be paid to constipation prophylaxis and treatment in ALL patients, particularly at the start of induction therapy.
- || fentanyl citrate / Generic mfg., sevoflurane / Generic mfg.
Clinical, Journal: Effect of dexmedetomidine on perioperative hemodynamics and organ protection in children with congenital heart disease: A randomized controlled trial. (Pubmed Central) - Jan 21, 2021
Increased attention should be paid to constipation prophylaxis and treatment in ALL patients, particularly at the start of induction therapy. Dex anesthesia can effectively maintain hemodynamic stability and diminish organ injuries in CHD children.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Women, opioid use and addiction. (Pubmed Central) - Jan 21, 2021
Thus, the public health crisis of opioid addiction has endured. This paper highlights the importance of understanding differences among women and men in opioid use and its biological and psychosocial effects to advance the gender-based treatment approaches and effective public health policy.
- | fentanyl citrate / Generic mfg.
Journal: Mass spectral similarity mapping applied to fentanyl analogs. (Pubmed Central) - Jan 20, 2021
When applied to a reference set of spectra for Type I fentanyl analogs (molecules differing from fentanyl by a single modification), the map illuminates clustering that is applicable to automated structure assignment of unidentified molecules. An open-source software implementation that generates mass spectral similarity mappings of unknowns against a library of Type I fentanyl analog spectra is available at http://github.com/asm3-nist/FentanylClassifier.
- || fentanyl citrate / Generic mfg., isoflurane / Generic mfg.
Clinical, Journal: Volatile Sedation for Acute Respiratory Distress Syndrome Patients on Venovenous Extracorporeal Membrane Oxygenation and Ultraprotective Ventilation. (Pubmed Central) - Jan 20, 2021
Aspartate aminotransferase levels were lower during the volatile sedation phases (p < 0.001), whereas alanine aminotransferase, triglycerides, and creatine phosphokinase were more altered during the IV sedation phase before isoflurane (p < 0.001). Volatile sedation represents an alternative to IV agents to achieve long-term deep sedation in critically ill patients on extracorporeal membrane oxygenation undergoing ultraprotective ventilation.
- ||| fentanyl citrate / Generic mfg.
No doubt. Overdoses are a big problem here in the City. Fentanyl has made the existing problem of opiate addiction much worse. (Twitter) - Jan 20, 2021
- || Neforex (nefopam) / Incepta
Clinical, Journal: Analgesic Efficacy of Nefopam as an Adjuvant in Patient-Controlled Analgesia for Acute Postoperative Pain After Laparoscopic Colorectal Cancer Surgery. (Pubmed Central) - Jan 17, 2021
The day of PCA discontinuation, time to pass flatus, length of the hospital stay, and incidence of nausea/vomiting, dizziness, and headache also did not differ between the groups. Fentanyl PCA with 80 mg of nefopam as an adjuvant did not have a superior analgesic effect after laparoscopic colorectal cancer surgery.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Deep Sedation for Pediatric Parotid Sialendoscopy in Juvenile Recurrent Parotitis. (Pubmed Central) - Jan 17, 2021
Effectiveness of sialendoscopy under deep sedation was subjectively attested by high positive scores obtained at post-operative standardized questionnaires administered to the patients and their parents, and objectively by the lack of clinical recurrences during the follow-up. The combination of propofol and fentanyl seems to be a reliable and safe means of sedating children with JRP undergoing sialendoscopy.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Analgesic efficacy and spread of local anesthetic in ultrasound-guided paravertebral, pectoralis II, and serratus anterior plane block for breast surgeries: A randomized controlled trial. (Pubmed Central) - Jan 16, 2021
Onset of sensory blockade, postoperative fentanyl consumption, and pain scores was measured...TPVB and SAP group result in a greater spread of the drug and provide equivalent analgesia and are superior to the PECS II block in providing analgesia for breast surgeries. SAP block is easier to perform than TPVB with lesser chances of complications and results in faster onset.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Pain, stress, analgesia and postpartum depression: Revisiting the controversy with a randomized controlled trial. (Pubmed Central) - Jan 16, 2021
CSE parturients received 0.5 ml of 0.5% hyperbaric bupivacaine intrathecally and PCEA with continuous infusion of 0.1% levobupivacaine and 2 μg/ml fentanyl @5 ml/h along with patient-controlled boluses with a lockout interval of 15 min...CSE analgesia in laboring parturients does not reduce PPD at 6 weeks. Instead, perceived high stress during pregnancy appears to be the most important factor.
- | fentanyl citrate / Generic mfg.
Retrospective data, Journal: Sedation with alfentanil versus fentanyl in patients receiving extracorporeal membrane oxygenation: outcomes from a single-centre retrospective study. (Pubmed Central) - Jan 15, 2021
There was a statistically significant reduction in some adjunctive sedatives in patients managed with a fentanyl-based regimen. Prospective studies are required to confirm these results.
- | ketamine / Generic mfg.
Journal: The Use of Ketamine for Air Medical Rapid Sequence Intubation Was Not Associated With a Decrease in Hypotension or Cardiopulmonary Arrest. (Pubmed Central) - Jan 15, 2021
The incidence of hypotension and arrest did not change over time despite an increase in the prevalence of ketamine use for air medical RSI. These data do not support a safer hemodynamic profile for ketamine.
- || fentanyl citrate / Generic mfg., remifentanil / Generic mfg.
Clinical, Journal: Does Erector Spinae Plane Block Have a Visceral Analgesic Effect?: A Randomized Controlled Trial. (Pubmed Central) - Jan 15, 2021
The significantly reduced opioid consumption in ESPB group may imply that while preliminary and in need of confirmation, ESPB has potential visceral analgesic effect. Therefore, performing ESPB solely may be feasible in inducing both somatic and visceral analgesia.
- || fentanyl citrate / Generic mfg., remifentanil / Generic mfg., sevoflurane / Generic mfg.
Clinical, Journal: Impact of short-acting vs. standard anaesthetic agents on obstructive sleep apnoea: a randomised, controlled, triple-blind trial. (Pubmed Central) - Jan 15, 2021
In conclusion, short-acting anaesthetic agents did not reduce the impact of general anaesthesia on sleep apnoea severity compared with standard agents. These data should prompt an update of current recommendations.
- | fentanyl citrate / Generic mfg.
Journal: Effect of combined acupuncture-medicine anesthesia in thyroid nodule ablation and its effect on serum β-endorphin (Pubmed Central) - Jan 15, 2021
In microwave ablation of benign thyroid nodules, combined acupuncture-medicine anesthesia has good sedative and analgesic effects and can reduce the amounts of anesthetics used as well as the incidence rates of intraoperative snore and respiratory depression. The analgesic effect of acupuncture anesthesia is associated with increased β-endorphin secretion.
- | ketamine / Generic mfg., amphetamine / Generic mfg.
Journal: Development and implementation of SafeMedWaste, a chemical denaturant for non-hazardous disposal of controlled medications. (Pubmed Central) - Jan 15, 2021
Another formulation of SafeMedWaste was tested on solid medications, which were fully denatured in 48-72 h. In conclusion, SafeMedWaste irreversibly denatures controlled medications that present a problem in our society.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Understanding the increase in opioid overdoses in New Hampshire: A rapid epidemiologic assessment. (Pubmed Central) - Jan 15, 2021
Despite consensus that fentanyl is the primary cause of overdoses, individuals continue to use it and affirm limited availability of resources to address the problem. Policies targeting innovative prevention, harm reduction, and treatment efforts are needed to more effectively address the crisis.
- | fentanyl citrate / Generic mfg.
Journal: Effect of positive urine fentanyl screen on attitudes toward heroin use. (Pubmed Central) - Jan 13, 2021
This study suggests a novel clinical utility in toxicology screens to inform behavior in the setting of illicit fentanyl exposure. In addition to linkages to evidence-based treatment, linkages to harm-mitigating strategies associated with ongoing substance use may be critical to a comprehensive overdose prevention strategy in the clinical setting.
- || fentanyl citrate / Generic mfg., chlorpromazine / Generic mfg.
Clinical, Retrospective data, Journal: Efficacy and safety of implantable cardioverter-defibrillator implantation in pediatric tachycardia cases (Pubmed Central) - Jan 13, 2021
ICD implantation is safe and effective in children and adolescent patients. The electric storm may happen after operation, which could be prevented by the comprehensive strategies including appropriate ICD parameter-setting, analgesics-sedatives treatment and psychological support.
- || Vecuron (vecuronium) / Sun Pharma
Clinical, Journal: Effects of different concentrations of desflurane on index of cardiac electrophysiological balance in gynecologic surgery patients. (Pubmed Central) - Jan 13, 2021
There was no significant difference in Tp-e interval and iCEB at any time (P>0.05). The study suggested that inhalation of desflurane at a normal concentration can not cause arrhythmogenic characteristics and affect the cardiac electrophysiologic stability.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial. (Pubmed Central) - Jan 13, 2021
Patients undergoing thyroid surgery with FLMA had less postoperative laryngopharyngeal symptoms when compared with ETT. The use of FLMA also achieved less buckling during extubation and better hemodynamic profiles during intubation.
- | Journal: OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery. (Pubmed Central) - Jan 13, 2021
No association was found between COMT haplotype and other pain outcomes or OPRM1 polymorphisms and the different pain modalities. COMT haplotype appears to explain part of the variability in acute postoperative pain in adult cardiac surgery patients.
- || Duragesic (fentanyl) / J&J
LOL. That reminds me I need to google is Limbaugh dead yet or at least on fentanyl patch😺 (Twitter) - Jan 12, 2021
- | fentanyl citrate / Generic mfg.
Journal: D-Amphetamine Accelerates Recovery of Consciousness and Respiratory Drive After High-Dose Fentanyl in Rats. (Pubmed Central) - Jan 12, 2021
Overall, d-amphetamine attenuated respiratory acidosis, increased arterial oxygenation, and accelerated the return of consciousness in the setting of fentanyl intoxication. This suggests that d-amphetamine may be a useful adjunct or alternative to opioid receptor antagonists such as naloxone.
- || fentanyl citrate / Generic mfg.
🤔🤷🏼♀️ I have sent relatively coherent work emails while intubated on propofol/fentanyl/dex so you have a high standard to beat 🤭😬 (Twitter) - Jan 10, 2021
- | fentanyl citrate / Generic mfg.
Journal: Detection and classification of fentanyl and its precursors by surface-enhanced Raman spectroscopy. (Pubmed Central) - Jan 9, 2021
The vibrational spectra of this family of analytes are very similar, making them difficult to distinguish by traditional means. In addition to taking advantage of the sensitivity provided by SERS, we developed a chemometric approach utilizing a hierarchical partial least squares-discriminant analysis algorithm that allowed us to distinguish spectra that possess many similar features.