fentanyl citrate / Generic mfg. 
Welcome,         Profile    Billing    Logout  
 39 Diseases   5 Trials   5 Trials   18506 News 


«12...164165166167168169170171172173174...222223»
  • ||||||||||  fentanyl citrate / Generic mfg., isoflurane / Generic mfg.
    Preclinical, Journal:  In vivo imaging of deep neural activity from the cortical surface during hippocampal epileptiform events in the rat brain using electrical impedance tomography. (Pubmed Central) -  Feb 20, 2021   
    These revealed a focus of neural activity localised to the dentate gyrus which was spatially and temporally aligned to local field potential (LFP) recordings and could be reconstructed reproducibly in all animals with a localisation accuracy of ≤400 μm (p < 0.03125, N = 5). These findings represent the first experimental evidence of the ability of EIT to image neural activity in subcortical structures from the surface of the cortex with high spatiotemporal resolution and suggest that this method may be used for improving understanding of functional connectivity between cortico-hippocampal networks in both physiological and pathophysiological states.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  The Opioid Epidemic Within the COVID-19 Pandemic: Drug Testing in 2020. (Pubmed Central) -  Feb 20, 2021   
    Among individuals tested, positivity increased by 35% for non-prescribed fentanyl and 44% for heroin during the pandemic...In summary, these findings demonstrate decreased drug testing overall, with increased positivity for high-risk drugs and dangerous drug combinations. The convergence of the drug abuse epidemic and COVID-19 pandemic has led to an increased need for health care and public health resources dedicated to supporting vulnerable patients and addressing the underlying causes of these disturbing trends.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Fentanyl transdermal patches induced chemical leucoderma. (Pubmed Central) -  Feb 20, 2021   
    Spontaneous repigmentation may occur after discontinuing the chemical exposure, and follow-ups are recommended to monitor whether spontaneous repigmentation occurs. Additionally, several treatment options have been proposed as specific treatments for chemical leucoderma, including psoralens, corticosteroids, calcineurin inhibitors, immunosuppressive agents and phototherapy.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Accurate prediction of terahertz spectra of molecular crystals of fentanyl and its analogs. (Pubmed Central) -  Feb 20, 2021   
    Further, the study of THz spectra of a series of stereoisomers shows that small changes in molecular structure results in distinct crystal packing and significantly alters THz spectra as well. We discuss spectral features of synthetic opioids with higher potency than conventional fentanyl such as ohmefentanyl and sufentanil and discover the pattern of THz spectra of fentanyl analogs.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Fentanyl is used in Mexico's northern border. Current challenges for drug health policies. (Pubmed Central) -  Feb 18, 2021   
    Pre-emptive ultrasound-guided mandibular nerve block reduces morphine consumption, prolongs the time for a request for rescue analgesic, reduces intraoperative fentanyl consumption, provides better control of intraoperative heart rate, and better pain scores postoperatively when compared to the postoperative mandibular nerve block. In a sample of 89 heroin users in Mexico, most white powder heroin users were unknowingly exposed to fentanyl, with fentanyl detected in 93% of white powder samples.
  • ||||||||||  fentanyl citrate / Generic mfg., methamphetamine / Generic mfg., methadone / Generic mfg.
    Journal:  Trends and Geographic Patterns in Drug and Synthetic Opioid Overdose Deaths - United States, 2013-2019. (Pubmed Central) -  Feb 18, 2021   
    From 2018 to 2019, the largest relative increase in the synthetic opioid-involved death rate occurred in the West (67.9%), and the largest relative increase in the psychostimulant-involved death rate occurred in the Northeast (43.8%); these increases represent important changes in the geographic distribution of drug overdose deaths. Evidence-based prevention and response strategies including substance use disorder treatment and overdose prevention and response efforts focused on polysubstance use must be adapted to address the evolving drug overdose epidemic.
  • ||||||||||  midazolam hydrochloride / Generic mfg.
    [VIRTUAL] UTILITY OF CAPNOGRAPHY DURING PRIMARY PERCUTANEOUS CORONARY INTERVENTION (eAbstract site) -  Feb 17, 2021 - Abstract #ACC2021ACC_5352;    
    The ASA capnography mandate for conscious sedation does not appear to provide benefit in primary PCI. The addition of another physiologic parameter, such as capnography, to display and monitor in the interventional cardiology setting should only become standard if there are clear patient safety benefits to compensate for the distractions of false alarms.
  • ||||||||||  midazolam hydrochloride / Generic mfg.
    [VIRTUAL] WOODEN CHEST SYNDROME (eAbstract site) -  Feb 17, 2021 - Abstract #ACC2021ACC_2965;    
    WCS is a rare complication that occurs within minutes of fentanyl administration and is characterized by sudden laryngospasm and respiratory failure. It can be treated promptly with naloxone, paralytics and mechanical ventilation if needed.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Changes in drug use behaviors coinciding with the emergence of illicit fentanyl among people who use drugs in Vancouver, Canada. (Pubmed Central) -  Feb 17, 2021   
    The majority of PWUD in our sample did not change their drug use behavior despite a high prevalence of fentanyl exposure, indicating a need for targeted behavior change messaging and overdose prevention efforts such as naloxone and addiction treatment for this sub-population of PWUD. Further, the high fentanyl exposure observed in our sample suggests a need to address upstream structural factors shaping the overdose risk in addition to individual behavioral change.
  • ||||||||||  dexmedetomidine / Generic mfg.
    Clinical, Journal:  Study of Dexmedetomidine in Caudal Block for Children Undergoing Inguino-scrotal Surgery. (Pubmed Central) -  Feb 16, 2021   
    The intraoperative requirement for supplement Fentanyl was significantly reduced in group B. Adverse events were comparable between the groups. Conclusion Dexmedetomidine prolongs the duration of analgesia when mixed with caudal Bupivacaine, without increasing adverse events.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Untargeted Metabolic Profiling of 4-Fluoro-Furanylfentanyl and Isobutyrylfentanyl in Mouse Hepatocytes and Urine by Means of LC-HRMS. (Pubmed Central) -  Feb 14, 2021   
    We have recently reported the characterization of two new analogs of fentanyl, i.e., 4-fluoro-furanylfentanyl (4F-FUF) and isobutyrylfentanyl (iBF), which were found for the first time in Italy in 2019; 4F-FUF was identified for the first time in Europe and was notified to the European Early Warning System...N-dealkylation of 4-FFUF dihydrodiol and oxidation to carbonyl metabolites for iBF were also major biotransformations. Despite some differences, in general there was a good agreement between in vitro and in vivo samples.
  • ||||||||||  ketamine / Generic mfg.
    Clinical, Journal:  Analgesia for trauma patients in emergency medicine (Pubmed Central) -  Feb 12, 2021   
    Basic prerequisites for safe and effective analgesia by healthcare professionals are the use of adequate monitoring, the provision of well-defined emergency equipment, and the mastery of emergency procedures. In a structured competence system, paramedics and nursing personnel can perform safe and effective analgesia.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Transdermal intoxication through broken opioid ampules : Accidental intoxication in a paramedic (Pubmed Central) -  Feb 12, 2021   
    He developed the typical clinical picture of opioid intoxication with clouding of consciousness, miosis, and respiratory depression. This necessitated continuous monitoring of vital signs as well as repetitive administration of naloxone under the improvised circumstances of a mission abroad.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Journal:  Two Cyclopropyl Fentanyl Case Studies in Los Angeles. (Pubmed Central) -  Feb 12, 2021   
    However, many of the fentalogs are only prevalent for a short amount of time as they are constantly changing to avoid detection and criminality. No other fatal cyclopropyl fentanyl cases have been identified in Los Angeles County Medical Examiner-Coroner cases since the fall 2017.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Postmortem Brain-Blood Ratios of Codeine, Fentanyl, Oxycodone and Tramadol. (Pubmed Central) -  Feb 12, 2021   
    Intravenous and transdermal fentanyl administration could not be distinguished based on the blood or brain concentration or the brain-blood ratio. The results of this study may benefit the toxicological investigation in postmortem cases where one of the four analgesics are suspected of having contributed to or caused a fatal intoxication.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Review, Journal:  Opioid transdermal delivery system: a useful method for pain management in children. (Pubmed Central) -  Feb 12, 2021   
    In this review, we describe the main features of the adhesive TDDS and the main characteristics of pediatric skin and the differences from the adult one. Moreover, we focus on fentanyl and buprenorphine patches and their non-invasive mechanism of action, and on the main aspects that make them suitable for pain management among the pediatric population.
  • ||||||||||  ketamine / Generic mfg.
    Review, Journal:  Narrative review of intrathecal drug delivery (IDD): indications, devices and potential complications. (Pubmed Central) -  Feb 12, 2021   
    The infusion pumps available on the market are both non-programmable (with continuous IT deliver of drugs) and programmable (with variable deliver of drugs according to their flow rate). Moreover, we describe the procedure of implantation and the potential complications of IT drug delivery (such as bleeding, infection, loss of cerebrospinal fluid, wound seroma, loss of catheter pump propellant).
  • ||||||||||  fentanyl citrate / Generic mfg.
    Retrospective data, Review, Journal:  Nebulized Fentanyl for Dyspnea: A Retrospective Chart Review. (Pubmed Central) -  Feb 10, 2021   
    Our preliminary data suggest that nebulized fentanyl has limited side effects and may have a role in the treatment of dyspnea. Further research is necessary to determine its efficacy.
  • ||||||||||  pregabalin / Generic mfg.
    Journal:  Fatal poisoning in drug addicts in the Nordic countries in 2017. (Pubmed Central) -  Feb 10, 2021   
    Pregabalin and gabapentin were detected in all countries, especially pregabalin, which was detected in 42% of the Finnish cases. New psychoactive substances (NPS) occurred in all countries except Iceland.