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- || fentanyl citrate / Generic mfg.
Clinical, Journal: Comparison of Caudal Block vs. Penile Block vs. Intravenous Fentanyl Only in Children Undergoing Penile Surgery: A Prospective, Randomized, Double Blind Study. (Pubmed Central) - Apr 13, 2021
Regional blocks most effectively controlled pain for 30 min after surgery. The choice of intra-operative analgesia protocol had no effect on later pain and recovery parameters.
- ||| fentanyl citrate / Generic mfg.
Overdoses were on the rise long before Covid. Fentanyl is the culprit, but you already knew that doc. Just because you are a doctor doesn’t mean you are an expert about everything. It seems you are trying to get this to fit your narrative, but this argument is weak. (Twitter) - Apr 12, 2021
- || fentanyl citrate / Generic mfg.
Overdose deaths have neen increasing pre-pandemic and do not in any way correlate with regions where there have been increased lockdowns. Most happening in the West where polysubstance abuse and increased contamination (particularly with fentanyl) of drugs have spiked recently (Twitter) - Apr 12, 2021
- ||| fentanyl citrate / Generic mfg.
yeah blame it on Covid and lockdowns and not on the USA abuse of medic drugs... "... deaths from illicitly manufactured fentanyl and synthetic opioids are driving the increase in overdose deaths..." In europe you cant even buy those... (Twitter) - Apr 12, 2021
- fentanyl citrate / Generic mfg., oxycodone controlled release / Generic mfg.
[VIRTUAL] Coverage of the Opioid Crisis in National Network Television News from 2000-2020- A Content Analysis () - Apr 12, 2021 - Abstract #ISPOR2021ISPOR_870;
National television networks have frequently utilized personal stories to put a face on the opioid crisis and have increasingly discussed strategies to combat it. Through media coverage, the general population may become more aware and educated about the impact of the crisis in the US.
- |||| fentanyl citrate / Generic mfg.
Clinical: We still don’t have a CLIA waived POC immunoassay UDS for fentanyl. How are we supposed to appropriately treat our addiction patients when our UDS cups lack the test for the most commonly abused and deadly opioid we face in our daily practice. (Twitter) - Apr 10, 2021
- ||| fentanyl citrate / Generic mfg.
Clinical: But not fentanyl, drunk driving, smoking weed?....so racists go to re-education camps and victims sue for emotional damage. Another case of virtue signaling to obfuscate the border + China dilemmas. (Twitter) - Apr 10, 2021
- |||| fentanyl citrate / Generic mfg., ketamine / Generic mfg.
Clinical: The question that keeps me up at night is how much do we make women suffer with inadequate regional anesthesia to avoid these bad outcomes associated with GA? IV fentanyl 100 mcg and inhaled nitrous probably ok, “room air GA” with ketamine probably not (Twitter) - Apr 10, 2021
- | fentanyl citrate / Generic mfg.
Preclinical, Journal: Lasting effects of repeated ∆9-tetrahydrocannabinol (THC) vapor inhalation during adolescence in male and female rats. (Pubmed Central) - Apr 10, 2021
Through media coverage, the general population may become more aware and educated about the impact of the crisis in the US. Repeated THC vapor inhalation in adolescent rats results in lasting consequences observable in adulthood.
- | fentanyl citrate / Generic mfg., methadone / Generic mfg.
Journal: The Opioid Epidemic: Challenge to Military Medicine and National Security. (Pubmed Central) - Apr 10, 2021
Future evaluations from ongoing federally funded programs to the states for addiction surveillance and intervention may help create measures to address the proliferation of opioid addiction with increased death rates. Anticipated results from these federal efforts should help inform opioid programs in military and veterans' health systems.
- | fentanyl citrate / Generic mfg.
Journal: Fentanyl Detection Using Eosin Y Paper Assays. (Pubmed Central) - Apr 10, 2021
Finally, eosin Y was able to detect fentanyl in forensic case samples containing heroin and various cutting agents. Based on our results, eosin Y has the potential to screen for fentanyl and fentanyl analogues and can detect fentanyl in low amounts when mixed with common cutting agents.
- | midazolam hydrochloride / Generic mfg.
Journal: Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs. (Pubmed Central) - Apr 10, 2021
Based on our results, eosin Y has the potential to screen for fentanyl and fentanyl analogues and can detect fentanyl in low amounts when mixed with common cutting agents. Midazolam co-induction reduced the propofol induction dose and improved the quality of induction in critically ill dogs without an improvement in cardiopulmonary variables, when compared with a higher dose of propofol alone.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Binaural Beats Reduce Postoperative Morphine Consumption in Older adults After Total Knee Replacement Surgery. (Pubmed Central) - Apr 10, 2021
During general anesthesia, binaural beat (BB) listening has been found to reduce intraoperative fentanyl consumption as well as postoperative pain scores and discharge time...BB stimulation before surgery can be successfully used as a nonpharmacological treatment to reduce morphine consumption in older adults who undergo knee replacement. The use of a noninvasive, safe, and inexpensive BB intervention can result in a positive effect on patients' postoperative recovery.
- | fentanyl citrate / Generic mfg.
Journal: Comparison between intravenous lidocaine and fentanyl on cough reflex and sympathetic response during endotracheal intubation in dogs. (Pubmed Central) - Apr 10, 2021
The use of a noninvasive, safe, and inexpensive BB intervention can result in a positive effect on patients' postoperative recovery. At the stated doses, whilst reducing the alfaxalone dose, fentanyl is superior to lidocaine in suppressing the cough reflex and blunting the increase in HR at endotracheal intubation in dogs premedicated with methadone.
- || fentanyl citrate / Generic mfg.
Clinical, Observational data, Journal: Incidence and Risk Factors for Delirium in Older Patients Following Intensive Care Unit Admission: A Prospective Observational Study. (Pubmed Central) - Apr 10, 2021
The factors found in this study to be independently associated with delirium include poor sleep quality and physical restraints. Both critical care physicians and nurses should pay greater attention to the quality of the ICU stay experienced by their older patients.
- | fentanyl citrate / Generic mfg.
Journal: Barriers and facilitators to a novel low-barrier hydromorphone distribution program in Vancouver, Canada: a qualitative study. (Pubmed Central) - Apr 10, 2021
In particular, lower-barrier design and operational features should be considered to improve uptake and engagement. Safe opioid supply programs are a promising intervention to address North America's ongoing overdose crisis by providing people at high risk of fatal overdose an alternative to the toxic drug supply.
- | fentanyl citrate / Generic mfg.
Journal: The cost of opioid use disorder and the value of aversion. (Pubmed Central) - Apr 10, 2021
The age-specific values of averting an OUD allow for more robust and targeted economic evaluations of competing interventions to reduce the burden of opioids on multiple stakeholders. The rise in the annual OUD-related cost largely reflects the increase in overdose deaths attributable to synthetic opioids (e.g., fentanyl).
- ||| fentanyl citrate / Generic mfg.
Clinical: @POTUS @VP @FLOTUS @CDCDirector @CDCgov. Wake up! About time someone shutting CDC GUIDELINES DOWN since CDC falsely input wrong stats recorded about the opioid ODs. They blame RX patients when its mostly 97% streetdrugs like fentanyl whos the blame!! (Twitter) - Apr 10, 2021
- || tramadol hydrochloride / Generic mfg., ibuprofen / Generic mfg.
Clinical, Journal: Prescribing of Nonsteroidal Anti-inflammatory Drugs, Tramadol, and Opioids in Children: Patterns of Its Utilization. (Pubmed Central) - Apr 10, 2021
Prescriptions for nine NSAIDs (diclofenac, ketoprofen, etoricoxib, celecoxib, ibuprofen, indomethacin, mefenamic acid, meloxicam, and naproxen), tramadol, and five other opioids (morphine, oxycodone, fentanyl, buprenorphine, and dihydrocodeine) prescribed for children aged 12 y.o.) with the majority for naproxen (13-15 y.o. (28.2%) and 16-17 y.o. (28.2%). Other frequently prescribed analgesics for older children included ibuprofen (20.6%) and diclofenac (18.2%) for 12-15 y.o. and diclofenac (26.7%) and tramadol (17.6%) for 16-17 y.o. Ibuprofen was the primary analgesic for children less than 12 y.o., whereas there was a wide range of analgesics prescribed for children age >12 y.o. including naproxen, diclofenac, and tramadol.
- | morphine/oxycodone (Q8011) / QRxPharma, pethidine / Samaritan
Journal: Ten Years of Strong Opioid Analgesics Consumption in Malaysia and Other Southeast Asian Countries. (Pubmed Central) - Apr 10, 2021
Growing trends of strong opioids consumption in all five Southeast Asian countries demonstrated in this study may indicate improved access to opioid analgesics in these countries. Given the increasing trends, it is important to ensure that the utilization of opioids is according to the guideline to prevent the negative consequences of opioids particularly when used in chronic non-cancer pain.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Long-Term Cognitive Outcomes and Sleep in Adults After Extracorporeal Life Support. (Pubmed Central) - Apr 10, 2021
No statistically significant difference was seen between patients treated with or without venovenous extracorporeal membrane oxygenation in the mean daily Riker Sedation Agitation Score; however, patients in the venovenous extracorporeal membrane oxygenation group received greater amounts of fentanyl over their ICU stay as compared to patients receiving conventional mechanical ventilation only (p < 0.001)...In this small retrospective case series, no significant differences were found in sleep or cognitive outcomes between extracorporeal life support and non-extracorporeal life support survivors. Further, in this hypothesis-generating study, differences in administered sedative doses during the ICU stay seen between the two groups did not impact 6- or 12-month cognitive performance or actigraphy-estimated sleep time.
- || fentanyl citrate / Generic mfg.
.@CDCgov & @SAMSHAgov announced federal funds can now be used to buy rapid #fentanylteststrips -- a move Healio Peer Perspective Board member @DocAnitaGupta called a "first step in gaining another tool" to fight the #opioidepidemic https://t.co/ROimv97YZo (Twitter) - Apr 9, 2021
- || fentanyl citrate / Generic mfg.
Doubtful, and you run the risk of standard government nonsense and medical fentanyl and its analogues that we use would get caught in the crossfire. (Twitter) - Apr 9, 2021
- || fentanyl citrate / Generic mfg.
The doctors who testified today hit the nail on the head. Fentanyl doesn't cause air hunger. Being prone, crushed to the pavement does. (Twitter) - Apr 8, 2021
- | fentanyl citrate / Generic mfg., methamphetamine / Generic mfg.
Fentanyl is not methamphetamine. (Twitter) - Apr 8, 2021
- ||| fentanyl citrate / Generic mfg., methadone / Generic mfg.
Yet...this is how CDC responded? ALL illicit fentanyl OD from 2005 on, coded as a pain medication prescription.. ALL methadone OD listed as pain med rx, even when 80% is prescribed to treat addiction? That's NOT an improvement @CDCDirector. Its fraud. https://t.co/qTGRrvNPv8 (Twitter) - Apr 8, 2021
- | fentanyl citrate / Generic mfg.
But you didn't stop the deaths from heroin, and fentanyl. (Twitter) - Apr 8, 2021
- || fentanyl citrate / Generic mfg., buprenorphine/naloxone sublingual film / Generic mfg.
They found suboxone in the car as well as pills containing fentanyl & meth. Still not sure he had suboxone in his system. (Twitter) - Apr 7, 2021
- ||| fentanyl citrate / Generic mfg., methadone / Generic mfg.
I was on methadone for a couple of yrs as a long acting pain Med when I was in palliative care. I didn't really like it. When I switched to a pain clinic which was integrated w/my PCP, they wouldn't prescribe it & put me on a fentanyl patch. (Twitter) - Apr 7, 2021
- || midazolam hydrochloride / Generic mfg.
Clinical, Journal, Pleural effusion: Rigid Mini-Thoracoscopy Versus Semirigid Thoracoscopy in Undiagnosed Exudative Pleural Effusion: The MINT Randomized Controlled Trial. (Pubmed Central) - Apr 7, 2021
Diagnostic yield of rigid mini-thoracoscopy is not superior to semirigid thoracoscopy. Use of semirigid thoracoscope may provide greater patient comfort.
- | fentanyl citrate / Generic mfg.
Journal: Trends in opioid prescribing in Estonia (2011-2017). (Pubmed Central) - Apr 7, 2021
The use of the most potent opioids (morphine, fentanyl) was higher in noncancer than in cancer patients. The use of prescription opioids is low, and raises concern about the potential undertreatment of cancer pain, in parallel with misuse of opioids for either noncancer pain or diversion.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Letter to Editor-Postoperative Single Shot Epidural Fentanyl and Bupivacaine for Postoperative Analgesia After Lumbar Decompression: A Prospective, Double-Blind Randomized Study. (Pubmed Central) - Apr 7, 2021
The use of prescription opioids is low, and raises concern about the potential undertreatment of cancer pain, in parallel with misuse of opioids for either noncancer pain or diversion. No abstract available
- | fentanyl citrate / Generic mfg.
Journal: Opioid-related overdose mortality in the era of fentanyl: Monitoring a shifting epidemic by person, place, and time. (Pubmed Central) - Apr 7, 2021
In the era of increased availability of illicitly manufactured fentanyl (2013-2017), there has been a disproportionate increase in opioid-related overdose deaths among urban NH Black Americans. Interventions for urban NH Black Americans are urgently needed to halt the increase in overdose deaths.
- | fentanyl citrate / Generic mfg.
Journal: Steep increases in fentanyl-related mortality west of the Mississippi River: Recent evidence from county and state surveillance. (Pubmed Central) - Apr 7, 2021
Fentanyl has spread westward, increasing deaths in the short-term and threatening to dramatically worsen the nation's already severe opioid epidemic in the long-term. Increasing the standard dose of naloxone, expanding Medicaid, improving coverage of addiction treatment, and public health educational campaigns should be prioritized.
- | fentanyl citrate / Generic mfg., methylprednisolone oral / Generic mfg., methamphetamine / Generic mfg.
Journal: What is the drug of choice of young festivalgoers? (Pubmed Central) - Apr 7, 2021
Increasing the standard dose of naloxone, expanding Medicaid, improving coverage of addiction treatment, and public health educational campaigns should be prioritized. The drugs of choice for the attendees of this school-leaver festival were MDMA and MDA.
- || levamisole / Generic mfg.
Clinical, Review, Journal: Levamisole - A Toxic Adulterant in Illicit Drug Preparations: A Review. (Pubmed Central) - Apr 7, 2021
Levamisole is not currently included in routine drug testing panels, although a variety of confirmatory testing techniques exist across a range of antemortem and postmortem specimen options. Because of its varying presence in illicit drug markets, both the medical and forensic communities need to be aware of levamisole and its potential impact on toxicological investigations.
- Vecuron (vecuronium) / Sun Pharma
[VIRTUAL] On this patient with HLHS s/p Norwood operation and the initial hemodynamic instability the BEST initial step in sedation is: A. Low dose morphine (25 mcg/kg/hr)/fentanyl (1 mcg/kg/hr) and low dose-Precedex (0.3 mcg/kg/hr). B. Low dose morphine (25 mcg/kg/hr)/fentanyl (1 mcg/kg/hr) and continuous vecuronium infusion. C. Low dose morphine/fentanyl and vecuronium at intermittent doses. D. None of the above. (Topic Essentials 1) - Apr 7, 2021 - Abstract #ACC2021ACC_8905;
Because of its varying presence in illicit drug markets, both the medical and forensic communities need to be aware of levamisole and its potential impact on toxicological investigations. There is no abstract associated with this presentation.
- || nefopam / Generic mfg.
Clinical, Journal, Head-to-Head: The Analgesic Efficacy of Nefopam in Patient-Controlled Analgesia after Laparoscopic Gynecologic Surgery: A Randomized, Double-Blind, Non-Inferiority Study. (Pubmed Central) - Apr 7, 2021
No significant intergroup differences were observed in the cumulative dose of PCA usage and incidence of postoperative nausea and vomiting (PONV). In laparoscopic gynecological surgery, nefopam alone showed limited efficacy for postoperative pain control.
- | fentanyl citrate / Generic mfg.
Journal: A Molecularly Imprinted Sol-Gel Electrochemical Sensor for Naloxone Determination. (Pubmed Central) - Apr 7, 2021
The sensor also showed good run-to-run repeatability and batch-to-batch performance reproducibility with relative standard deviations (RSD) of 2.5-7.8% (n = 3) and 9.2% (n = 4), respectively. The developed sensor displayed excellent selectivity towards NLX compared to structurally similar compounds (codeine, fentanyl, naltrexone and noroxymorphone), and was successfully used to measure NLX in synthetic urine samples yielding recoveries greater than 88%.
- || midazolam hydrochloride / Generic mfg.
Clinical, Journal: Comparison of Two Different Sedation Protocols during Transvaginal Oocyte Retrieval: Effects on Propofol Consumption and IVF Outcome: A Prospective Cohort Study. (Pubmed Central) - Apr 7, 2021
From the IVF/ICSI secondary outcome parameters, we found a higher quality of embryos on day three in the study compared to the control group (p = 0.040). The comparison of the other secondary outcomes yielded non-significant differences; (4) The use of dexmedetomidine, as an alternative agent during OR, was associated with higher propofol consumption as a rescue dose compared to remifentanil but was linked with similar fertilization rates and higher quality of embryos produced.
- | fentanyl citrate / Generic mfg., methadone / Generic mfg.
Journal: Use of Spinal Anaesthesia with Anaesthetic Block of Intercostal Nerves Compared to a Continuous Infusion of Sufentanyl to Improve Analgesia in Cats Undergoing Unilateral Mastectomy. (Pubmed Central) - Apr 7, 2021
Four patients in the LR group required an extra dose of methadone after they achieved the sternal decubitus position, whereas those in the SUF group required many more doses. The analgesia achieved in the LR group was more satisfactory than that in the SUF group.
- || fentanyl citrate / Generic mfg.
Clinical, Journal: Randomized controlled trial comparing the efficacy of pectoral nerve block with general anesthesia alone in patients undergoing unilateral mastectomy. (Pubmed Central) - Apr 7, 2021
The secondary outcomes were post-operative pain scores at 2, 4, 6, 12, 18, and 24 h, total intraoperative fentanyl consumption, time to rescue analgesia, post-operative nausea vomiting, and complications, if any...Clinical Trials Registry of India, (CTRI/2017/04/008289). ctri.nic.in.
- || fentanyl citrate / Generic mfg., ketamine / Generic mfg.
Clinical, Journal: Comparative Study Among Ketamine, Fentanyl, and Ropivacaine, as Pre-incisional Analgesic Given by Surgical Site Infiltration, in Cases Posted for Elective Lower Segment Cesarean Section Under General Anesthesia. (Pubmed Central) - Apr 7, 2021
Conclusion Ketamine infiltration resulted in a better hemodynamic profile, a significantly longer duration of the postoperative pain-free interval, and more sedation in the postoperative anesthesia care unit (PACU). It did not affect the fetal wellbeing, as discernable from the APGAR scores.
- || ketamine / Generic mfg.
Review, Journal: Effect of anesthesia on electrocorticography for localization of epileptic focus: Literature review and future directions. (Pubmed Central) - Apr 7, 2021
There is evidence to avoid halothane, nitrous oxide, etomidate, ketamine, thiopental, methohexital, midazolam, fentanyl, and alfentanil due to undesired effects...The proper use of anesthetic agents and careful dose titration, and effective communication between the neurophysiologist and anesthesiologist based on ECoG activity are essential in optimizing recordings. Anesthesia is a crucial variate to consider in the design of studies investigating ECoG and related biomarkers.
- ||| fentanyl citrate / Generic mfg.
Only seen "excited delirium" regarding deaths in custody. Never in any other context. Regular delirium not lethal in isolation, & doesn't come on suddenly w/out cause in someone who was acting normally before. Drug intoxication from opioids like fentanyl present very differently. (Twitter) - Apr 6, 2021
- |||| fentanyl citrate / Generic mfg.
Clinical: Morphine? Kid stuff, ask @TGHCares they administer fentanyl to patients who aren’t in pain! 😉😉we know the real reason is #StealthEuthanasia (Twitter) - Apr 6, 2021
- || fentanyl citrate / Generic mfg.
There's as far as I know very little intentional morphine because it's hard to get. You can't really make it without Poppies. It's turned to heroin to boost its value but I suppose a few ppl might be using morphine itself. Fentanyl is definitely mostly illicitly made. (Twitter) - Apr 4, 2021
- || fentanyl citrate / Generic mfg.
*illicit fentanyl analog* which is distinct from fentanyl Rx’d for medical use. (Twitter) - Apr 4, 2021
- || fentanyl citrate / Generic mfg.
Well, peacock, it's a tie. I recently lost my stepson to fentanyl. And I often respond to assholes on Twitter. It's kind of a hobby. (Twitter) - Apr 4, 2021
- fentanyl citrate / Generic mfg.
[VIRTUAL] Evaluation of Commercially Available Cannabidiol Oils on the Metabolism of Commonly Prescribed Opioid Medications () - Apr 4, 2021 - Abstract #CPNP2021CPNP_31;
Materials and Five different commercial CBD oils at six different concentrations were tested with fentanyl, hydrocodone, and oxycodone... The findings of this study suggest that CBD oil could potentially inhibit the metabolism of these specific opioids putting the patient at increased risk of adverse events and toxicity when these drugs are taken concomitantly.