fentanyl citrate / Generic mfg. 
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  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Multidisciplinary Team Reviews of Drug Overdose Deaths and the Use of Minigrants to Advance Recommendations: A Statewide Pilot in Rhode Island. (Pubmed Central) -  Apr 27, 2021   
    The RI Department of Health was able to successfully pilot a multidisciplinary review process for overdose deaths and has recently institutionalized this process through legislation. The successful implementation of many of the team's community-oriented recommendations, supported through a minigrant process, highlights the impact that small financial investments can have to address the opioid epidemic and may be a model for other jurisdictions seeking to advance recommendations from these types of reviews.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Delivering Opioid Overdose Prevention in Bars and Nightclubs: A Public Awareness Pilot in New York City. (Pubmed Central) -  Apr 27, 2021   
    The campaign's rapid dissemination reached people at potential risk of opioid overdose in a short period of time following the identification of fentanyl in the cocaine supply. Public health authorities in states with high rates of opioid-involved overdose death should consider similar campaigns to deliver overdose prevention education in the context of a drug supply containing fentanyl.
  • ||||||||||  fentanyl citrate / Generic mfg., methamphetamine / Generic mfg.
    Journal:  Shifts in drug seizures in the United States during the COVID-19 pandemic. (Pubmed Central) -  Apr 27, 2021   
    The COVID-19 pandemic was associated with an immediate decrease in marijuana and methamphetamine seizures, and then increases throughout 2020 with some months exceeding the number (and weights) of seizures from the previous year. More research is warranted to determine the extent to which these seizures reflect changes in drug use.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Network Analysis and Visualisation of Opioid Prescribing Data. (Pubmed Central) -  Apr 24, 2021   
    Prescribing data for Fentanyl patches, a strong opioid with high potential for misuse and subsequent harm, across Queensland, Australia from 2011 to 2018 is analysed as an example of using network analysis, where prescribing patterns are viewed as a dynamic, bipartite graph of the interactions between patients and prescribers over time...A variety of network statistics that measure network structural and dynamic properties are presented to reveal the characteristics and trends of drug seeking and prescribing behaviours. This approach has been recognised by healthcare professionals at Queensland Health as leading to new and useful insights on the relationship between patients and prescribers and supporting their advisory role to reduce patient harm from inappropriate use of prescription drugs.
  • ||||||||||  Belviq (lorcaserin) / Eisai
    Preclinical, Journal:  Adjunctive effect of the serotonin 5-HT receptor agonist lorcaserin on opioid-induced antinociception in mice. (Pubmed Central) -  Apr 24, 2021   
    Lorcaserin (s.c.) did not alter the brain or blood concentrations of oxycodone, which suggests that its adjunctive effects on opioid-induced antinociception do not depend upon changes in opioid metabolism. Together, these data indicate that lorcaserin-mediated activation of the 5-HTR may represent a new pharmacological approach to augment opioid-induced antinociception.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Review, Journal:  History of Respiratory Stimulants. (Pubmed Central) -  Apr 24, 2021   
    Unfortunately, two new troubling phenomena force a reconsideration of the status-quo: (1) overdoses due to highly potent opioids such as fentanyl, and even more-potent licit and illicit fentanyl analogs, and (2) overdose due to polysubstance use (the combination of an opioid plus one or more non-opioid drug, such as a benzodiazepine, sedating antidepressant, skeletal muscle relaxant, or various other agents)...This interest can be informed by a short review of the history of this interesting class of medications. We present a short history of the trajectory of advances toward more selective and safer respiratory stimulants.
  • ||||||||||  midazolam hydrochloride / Generic mfg.
    Review, Journal:  Opioids for newborn infants receiving mechanical ventilation. (Pubmed Central) -  Apr 22, 2021   
    We are uncertain whether opioids have an effect on pain and neurodevelopmental outcomes at 18 to 24 months; the use of morphine or fentanyl probably has little or no effect in reducing the duration of mechanical ventilation and neonatal mortality. Data on the other comparisons planned in this review (opioids versus analgesics; opioids versus other opioids) are extremely limited and do not allow any conclusions. In the absence of firm evidence to support a routine policy, opioids should be used selectively - based on clinical judgement and evaluation of pain indicators - although pain measurement in newborns has limitations.
  • ||||||||||  fentanyl citrate / Generic mfg., sevoflurane / Generic mfg., rocuronium / Generic mfg.
    Clinical, Journal:  Evaluation of a Safety Protocol for the Management of Thirst in the Postoperative Period. (Pubmed Central) -  Apr 21, 2021   
    Level of consciousness was the main criterion of disapproval. The protocol identified crucial clinical conditions that made it impossible for the patient to receive thirst relief strategies and demonstrated that thirst can be satiated precociously with safety.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Lever-press duration as a measure of frustration in sucrose and drug reinforcement. (Pubmed Central) -  Apr 20, 2021   
    These data also show that average bar-press durations do not correlate with the number of bar presses, meaning that press duration is an independent measurement that represents a behavioral construct distinct from craving, which is typically measured with number of bar presses. Essentially, these results support that bar press durations can be used as a real-time measure of frustration as a 4th major facet of addiction-related behavior, adding to craving, impulsivity, and habit.
  • ||||||||||  fentanyl citrate / Generic mfg., methadone / Generic mfg.
    Clinical, Journal:  Increased HIV testing in people who use drugs hospitalized in the first wave of the COVID-19 pandemic. (Pubmed Central) -  Apr 17, 2021   
    Contrary to our hypothesis, HIV testing increased during the COVID-19 pandemic, and we discuss explanations for this finding. The decrease in HIV testing post-pandemic peak is a reminder that we must work to develop interventions that lead to sustained high rates of HIV testing for all people, and especially for PWUD.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Synergistic Recognition-Triggered Charge Transfer Enables Rapid Visual Colorimetric Detection of Fentanyl. (Pubmed Central) -  Apr 16, 2021   
    Additionally, we successfully fabricate a smartphone-based portable device to determine FTN, which is appropriate for field tests. The present work not only provides the first visual assay for FTN but also reveals the molecular structure-property relationship, which will guide the design and development of various probes for recognizing FTN.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Death in Sauna Associated With a Transdermal Fentanyl Patch. (Pubmed Central) -  Apr 14, 2021   
    The cause of death was determined to be fatal poisoning by fentanyl with the contributing factor of external heat from the sauna.Risks associated with transdermal administration of a potent opioid-like fentanyl are widely described in the scientific literature and described in the manufacturer's summary of product characteristics. Physicians and pharmacists should take particular care to ensure that patients understand these risks.
  • ||||||||||  fentanyl citrate / Generic mfg.
    [VIRTUAL] Injectable Weekly and Monthly Buprenorphine in the Outpatient Treatment of Fentanyl Users with Oud. () -  Apr 13, 2021 - Abstract #ASCP2021ASCP_7;    
    Consistent with previous post-hoc analyses of subgroups reporting heroin or IV drug use at baseline, treatment with CAM2038 resulted in a greater percentage of urine samples negative for illicit opioids in participants with evidence of fentanyl use prior to randomization vs SL BPN/NX. CAM2038 may have an advantage over SL BPN/NX on illicit opioid use outcome among difficult-to-treat patient population, including those who test positive for fentanyl at treatment initiation.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Journal:  Online Conversation Monitoring to Understand the Opioid Epidemic: Epidemiological Surveillance Study. (Pubmed Central) -  Apr 13, 2021   
    Furthermore, content was notably different based on media origin, and studies that exclusively use either social media sites (such as Twitter) or blogs and forums could miss important content. This study sets out sustainable, ongoing methodology for surveilling internet postings regarding these drugs.
  • ||||||||||  fentanyl citrate / Generic mfg., methamphetamine / Generic mfg.
    Clinical, Journal:  Impact of polysubstance use on high-sensitivity cardiac troponin I over time in homeless and unstably housed women. (Pubmed Central) -  Apr 13, 2021   
    Fentanyl use and the co-use of cocaine and alcohol are associated with myocardial injury, suggesting that the use of these substances may act as long-term cardiac insults. Whether risk counseling on these specific substances and/or including their use in CVD risk stratification would improve CVD outcomes in populations where substance use is high merits further investigation.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Clinical, Journal:  Fentanyl analog positivity among near-real-time urine drug test results in patients seeking health care. (Pubmed Central) -  Apr 13, 2021   
    However, acetyl fentanyl and 4-ANPP positivity may not be consistent with fentanyl analog use since both are process impurities, and 4-ANPP is a metabolite of fentanyl. Near-real-time, definitive UDT results reveal fentanyl analogs in patients seeking health care, helping clinicians and public health officials better understand their contribution to overdoses and help mitigate the risks they pose.
  • ||||||||||  fentanyl citrate / Generic mfg.
    Journal:  Implementing an Integrated Multi-Technology Platform for Drug Checking: Social, Scientific, and Technological Considerations. (Pubmed Central) -  Apr 13, 2021   
    The illicit drug overdose crisis in North America continues to devastate communities with fentanyl detected in the majority of illicit drug overdose deaths...We also highlight the implementation of a various service models that co-exist in a research setting, with particular emphasis on the way that drug checking technicians and harm reduction workers interact with service users. Finally, we provide a description of the challenges associated with data interpretation and the communication of results to a diverse audience.
  • ||||||||||  pregabalin / Generic mfg.
    Journal:  Premedication with pregabalin 150mg versus 300mg for postoperative pain relief after laparoscopic cholecystectomy. (Pubmed Central) -  Apr 13, 2021   
    The total amount of fentanyl required in 24 h was least in group B (228.33 ± 42.41μg) followed by group A (292.50 ± 46.49μg) and group C (322.50 ± 39.58μg) (P-value 0.0001). The incidence of sedation, dizziness, and visual disturbances was more in group B as compared to group A and was least in group C. Pregabalin 150 mg is effective in decreasing postoperative pain after laparoscopic cholecystectomy with fewer incidences of adverse effects such as sedation and visual disturbances as compared to pregabalin 300 mg.