tizanidine / Generic mfg. |
ChiCTR2000039318: Comparison of diclofenac with tramadol, tizanidine or placebo in the treatment of acute low back pain: multi-centre randomised controlled trial |
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| Recruiting | 4 | 369 | | encapsulated tramadol plus encapsulated tizanidine like placebo ;encapsulated tizanidine plus encapsulated tramadol like placebo ;encapsulated tramadol like placebo plus encapsulated tizanidine like placebo | Food and Health Bureau, Hong Kong SAR Government; Level of the institution:, Health and Medical Research Fund | adults aged from 18-65 with acute non-specific low back pain | | | | |
ChiCTR2000040075: Clinical study on prophylactic treatment of migraine with tizanidine |
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| Not yet recruiting | 4 | 150 | | placebo tid ;Tizanidine 1mg tid ;Tizanidine 2mg tid | West China Hospital, Sichuan University; West China Hospital, Sichuan University, 2020JDJQ0018 | Migraine | | | | |
NCT05488847: Opioid-Free Pain Protocol After Shoulder Arthroplasty |
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| Recruiting | 4 | 80 | US | Celecoxib, Celebrex, Pregabalin, Lyrica, Tramadol, Ultram, Dexamethasone, Decadron, Acetaminophen, tylenol, Ropivicaine, naropin, Epinephrine, Ketorolac, Tizanidine, Zanaflex, Magnesium, magnesium oxide, Ibuprofen, Motrin, Oxycodone Hydrochloride 5 Mg, Roxicodone | Henry Ford Health System | Shoulder Arthropathy, Shoulder Pain | 12/24 | 12/25 | | |
ChiCTR2300068058: Effect of drug metabolizing enzyme gene on drug metabolism in migraineurs treated with Tizanidine |
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| Not yet recruiting | 4 | 150 | | Tizanidine hydrochloride tablets(1mg,TID) ;Tizanidine hydrochloride tablets (1mg in the morning and at noon, 2mg in the evening) ;Tizanidine hydrochloride tablets(2mg,TID) | West China Hospital, Sichuan University; West China Hospital, Sichuan University, Major neuropsychiatric diseases - new target for the prevention and treatment of epilepsy (2020JDJQ0018) | migraine | | | | |
NCT06382662: Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cognition |
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| Recruiting | 4 | 20 | US | metaxalone m640, Metaxalone 640, tizanidine, Zanaflex | Primus Pharmaceuticals, Sun Valley Arthritis Center | Cognitive Impairment | 04/25 | 04/25 | | |
NCT06303076: Tizanidine vs. Zolpidem in Primary Insomnia: A Randomized Trial |
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| Not yet recruiting | 4 | 90 | NA | Tizanidine Hcl 4Mg Tab, Zolpidem Tartrate 10 mg | Sultan Qaboos University | Depressive Disorder, Major | 09/26 | 12/26 | | |
ChiCTR2300072407: Safety and efficacy of oral tizanidine hydrochloride in preventing migraine attacks in adults with migraine |
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| Recruiting | 4 | 189 | | Tizanidine hydrochloride 1mg tid, 1mg/ tablet ;Tizanidine hydrochloride 2mg tid, 2mg/ tablet ;Placebo 1 tablet tid | The Second Affiliated Hospital of Zhejiang University School of Medicine; The Second Affiliated Hospital of Zhejiang University School of Medicine, Sichuan Keride Pharmaceutical Co., LTD | migraine | | | | |
NCT06258785: Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous Suspension |
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| Not yet recruiting | 3 | 30 | NA | Tizanidine, Zanaflex | NorthShore University HealthSystem | Postoperative Urinary Retention, Sacrospinous Vaginal Vault Suspension, Reconstructive Pelvic Surgery | 12/24 | 04/25 | | |
NCT05484349: TIzanidine for the Preventive Treatment of Episodic MigrainE (TIME) |
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| Recruiting | 3 | 189 | RoW | Tizanidine Hydrochloride, Tizanidine Hydrochloride Placebo | Second Affiliated Hospital, School of Medicine, Zhejiang University, SICHUAN CREDIT PHARMACEUTICAL CO., LTD. | Migraine Without Aura, Migraine With Aura | 12/25 | 12/25 | | |
NCT06027099: CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial |
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| Not yet recruiting | 3 | 375 | NA | Tizanidine, MI-Opioid Taper, Placebo, Enhanced Usual Care | Stanford University | Chronic Pain, Back Pain, Neck Pain, Opioid Misuse | 01/28 | 07/28 | | |
2015-003770-32: A Randomized, Double-Blind, Four Treatment, Four period, Crossover Study, with Placebo, Tizanidine Immediate Release and Diphenhydramine to Study the Effect of Tizanidine Extended Release on Simulated Driving Performance, Cognitive, and Psychomotor Functioning |
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| Ongoing | 2 | 24 | Europe | Tizanidine Extended Release Tablets 12 mg, Zanaflex Tablets 4 mg, GALPHARM ONE A NIGHT NIGHTCALM 50MG TABLETS (Diphenhydramine Hydrochloride), Zanaflex Tablets, GALPHARM ONE A NIGHT NIGHTCALM 50MG TABLETS, Zanaflex Tablets, GALPHARM ONE A NIGHT NIGHTCALM 50MG TABLETS | Sun Pharma Advanced Research Company, Sun Pharma Advanced Research Company | healthy volunteers (acute musculoskeletal pain) | | | | |
NCT04429347: Gabapentin and Tizanidine for Insomnia in Chronic Pain |
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| Enrolling by invitation | 2 | 24 | US | Gabapentin, Neurontin, Placebo, Sham, Sugar Pill, Tizanidine, Zanaflex | University of California, San Diego, National Center for Advancing Translational Sciences (NCATS) | Insomnia Due to Medical Condition, Chronic Pain | 07/24 | 07/25 | | |
ACTRN12624001134516: Comparative, Multiple-Dose, Fixed Sequence, Pharmacokinetic Study of 2 Sizes of Daily MRX-4TZT TDS (Tizanidine Transdermal Delivery System) Applied for 3 Days and 2 Dose Levels of Oral Tizanidine in Healthy Adult Subjects |
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| Not yet recruiting | 1 | 24 | | | MEDRx Australia Pty Ltd , MEDRx Australia Pty Ltd | Spasticity | | | | |
NCT06274021: Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury |
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| Recruiting | 1 | 16 | US | Transcutaneous spinal stimulation at 100 Hz, Transcutaneous spinal stimulation at 50 Hz, Transcutaneous spinal stimulation at 50 Hz and single dose of baclofen, Transcutaneous spinal stimulation at 50 Hz and single dose of tizanidine, Sham transcutaneous spinal stimulation | University of Mississippi Medical Center, Methodist Rehabilitation Center, The Craig H. Neilsen Foundation | Spinal Cord Injuries, Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic | 12/25 | 12/25 | | |
NCT05789173: Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK |
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| Recruiting | 1 | 60 | US | Methadone and Tizanidine, Efavirenz, Methadone and Tizanidine | Indiana University, National Institute of General Medical Sciences (NIGMS) | Drug-Drug Interaction | 04/26 | 04/26 | | |
NCT05852093: Clinical Study on the Effect of Tizanidine on the Function and Pain of Patients After Shoulder Arthroscopy |
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| Not yet recruiting | 1 | 100 | NA | Celecoxib+Buprenorphine Transdermal Patch, Celecoxib+Buprenorphine Transdermal Patch+Tizanidine | Second Affiliated Hospital, School of Medicine, Zhejiang University | Rotator Cuff Tears | 06/26 | 06/27 | | |
NCT04574791: Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee Arthroplasty |
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| Enrolling by invitation | N/A | 240 | US | TiZANidine 2 MG Oral Capsule | Rothman Institute Orthopaedics | Pain, Postoperative | 09/21 | 09/21 | | |
ChiCTR2000040107: Clinical study of tizanidine combined with intrathecal analgesic pump on cancer pain |
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| Not yet recruiting | N/A | 20 | | intrathecal analgesic pump ;tizanidine + intrathecal analgesic pump | Affiliated Hospital of Qingdao University; Affiliated Hospital of Qingdao University, Self-pay | cancer pain | | | | |
ChiCTR2000040108: Clinical study of tizanidine combined with pregabalin on post herpes neuralgia |
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| Not yet recruiting | N/A | 40 | | pregabalin ;tizanidine+pregabalin | Affiliated Hospital of Qingdao University; Affiliated Hospital of Qingdao University, Self-pay | post herpes neuralgia | | | | |
ChiCTR2300077964: An exploratory study of clinical efficacy of Tizanidine hydrochloride tablets combined with acreoxib tablets in improving knee osteoarthritis |
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| Not yet recruiting | N/A | 176 | | Tizanidine hydrochloride tablets combined with imrecoxib tablets; Oral imrecoxib tablets | West China Hospital of Sichuan University; West China Hospital of Sichuan University, Beijing Life Oasis public Service Center | knee osteoarthritis | | | | |