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HS135, a Novel Activin and GDF Trap, Is Efficacious in Models of Pulmonary Hypertension (PH) and Heart Failure (HF) (Walter E. Washington Convention Center, Area B, Hall C (Lower Level)) - Mar 25, 2023 - Abstract #ATS2023ATS_5746; The best-in-class target engagement profile of HS135 translates into increased and differentiated efficacy improving the PH and HF phenotype in preclinical models. Collectively, these data support the development of HS135 as a novel agent in cardiometabolic and cardiopulmonary diseases including PAH and PH-associated with left heart disease.
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