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PROTAC tau degrader for the treatment of Alzheimer (In-Person) - Jul 6, 2023 - Abstract #AAIC2023AAIC_8193; Tau PROTAC degrader generated from proprietary tau warhead can selectively decrease the oligomer/aggregated tau in both in vitro and in vivo models. Current effort is focused on optimization of ADME properties of tau degrader as a promising therapy for AD primary tauopathies.
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