| Amsidine (amsacrine) / Kyowa Kirin |
2014-000652-28: Study protocol for acute myeloid leukemia in children and adolescent protocollo per la leucemia acuta mieloide in età pediatrica |
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| Ongoing | 3 | 300 | Europe | AMSIDYL, MYOCET, Solution for infusion, AMSIDYL, myocet | A.I.E.O.P., ospedale pediatrico Bambino Gesù rome | pediatric patient with acute myeloid leukemia pazienti in età pediatrica affetti da leucemia acuta mieloide, pediatric patient with acute myeloid leukemia pazienti in età pediatrica affetti da leucemia acuta mieloide, Diseases [C] - Cancer [C04] | | | | |
2005-000279-16: Phase III Clinical Study of Allogeneic Stem Cell Transplantation with Reduced Conditioning(RICT) versus Best Standard of Care in Acute Myeloid Leukemia (AML) in First Complete Remission |
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| Ongoing | 3 | 10 | Europe | Mylotarg, Fludara, Busilvex, Cytarabine, Zavedos, Novantone, Amekrin, Etopofos, Mylotarg, Fludara, Busilvex, Cytarabine, Zavedos, Novantone, Amekrin, Etopofos, Mylotarg | Sahlgrenska University Hospital | Acute myeloid leukemia in first complete remission | | | | |
| Recruiting | 3 | 142 | Europe | Dexamethasone, Amsacrine, Cytarabine, Azacitidine | University Hospital, Toulouse | Relapsed or Refractory Acute Myeloid Leukemia | 12/25 | 12/25 | | |
| Active, not recruiting | 2/3 | 745 | Europe | Amsacrine, Clofarabine, Cyclophosphamide, Cytarabine, Daunorubicin hydrochloride, Dexamethasone, Doxorubicin hydrochloride, Etoposide phosphate, Mercaptopurine, Methotrexate, Methylprednisolone, Pegaspargase, Thioguanine, Vincristine sulfate, Whole-brain radiation therapy | Universitätsklinikum Hamburg-Eppendorf | Leukemia | 12/19 | 12/24 | | |
2012-004421-24: Sequential FLAMSA chemotherapy and T cell depleted reduced intensity conditioning allogeneic stem cell transplantation (TCD FLAMSA-RIC alloSCT) in elderly acute myeloid leukemia and high risk myelodysplasia patients FLAMSA chemotherapie direct gevolgd door donor stamceltransplantatie bij patiënten met acute myeloide leukemie (AML) of hoog risico myelodysplasie (MDS) |
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| Ongoing | 2 | 15 | Europe | Amsacrine, cytarabine, RVG 09084, RVG 11013, Solution for infusion | Leiden Universtity Medical Center, Leiden Universtity Medical Center | acute myeloid leukemia and high risk myelodysplasia Acute myeloide leukemie en hoog risico myelodysplasie, acute myeloid leukemia (AML) and high risk myelodysplasia (MDS) Acute myeloide leukemie (AML) en hoog risico myelodysplasie (MDS), Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
2012-005538-12: A Randomised Trial of the FLAMSA-BU Conditioning Regimen in Patients with Acute Myeloid Leukaemia and Myelodysplasia Undergoing Allogeneic Stem Cell Transplantation |
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| Ongoing | 2 | 170 | Europe | Alemtuzumab, Fludarabine, Melphalan, Busilvex, Cytarabine, Amsacrine, Thymoglobulin, Alemtuzumab, Fludarabine, Melphalan, Busulphan, Cytarabine, Amsacrine, Anti-thymocyte Globulin (Rabbit), Campath, Busilvex, Thymoglobulin, Campath, Busilvex, Thymoglobulin | University of Birmingham, Leukaemia and Lymphoma Research, Pierre Fabre | Acute Myeloid Leukaemia (AML) and Myelodysplasia (MDS) | | | | |
2022-002435-66: Trial evaluating the safety and efficacy of Venetoclax in addition to a standard conditioning regime in patients with certain forms of leukemia undergoing allogeneic blood stem cell transplantation Studie zur Bewertung der Sicherheit und Wirksamkeit von Venetoclax zusätzlich zu einer Standard-Konditionierung bei Patienten mit bestimmten Formen von Leukämie, die sich einer allogenen Blutstammzelltransplantation unterziehen |
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| Not yet recruiting | 2 | 38 | Europe | Film-coated tablet, , Venclyxto | Heinrich-Heine-Universität Düsseldorf represented by the Coordinating Investigator, AbbVie Deutschland GmbH & Co. KG, Medac GmbH, Eurocept International B.V. | Patients with myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML) or secondary acute myeloid leukemia (sAML) before stem cell transplantation Patienten mit myelodysplastischem Syndrom (MDS), chronischer myelomonozytärer Leukämie (CMML) oder sekundärer akuter myeloischer Leukämie (sAML) vor Stammzelltransplantation, Patients with certain forms of leukemia before stem cell transplantation Patienten mit bestimmten Formen von Leukämie vor Stammzelltransplantation, Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
NCT05807932: Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML |
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| Recruiting | 1/2 | 38 | Europe | Venetoclax, Amsacrine, Ara-C, Tacrolimus, Mycophenolate Mofetil | Heinrich-Heine University, Duesseldorf, Koordinierungszentrum für Klinische Studien - Duesseldorf | Myelodysplastic Syndromes, Secondary Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia | 01/26 | 01/28 | | |
