levetiracetam / Generic mfg. 
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111 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
levetiracetam / Generic mfg.
ACTRN12608000293369: Intravenous Levetiracetam in the Acute Management of Seizures

Not yet recruiting
4
20
 
Prof. David C. Reutens, UCB Pharma
acute seizures
 
 
ACTRN12606000102572: Neuropsychiatric, Neurocognitive And Quality Of Life Outcomes In Patients With Epilepsy Treated With Levetiracetam (Keppra) Verses Older AEDs As First Substitution Monotherapy.

Recruiting
4
200
 
Associate Prof. Terence O'Brien and RMH Neurosciences Foundation, UCB Pharma Belgium
Epilepsy
 
 
ACTRN12615000643572: EpiNet-First Trial 1: Comparison of efficacy of levetiracetam, lamotrigine and carbamazepine in people with previously untreated epilepsy who have focal seizures.

Recruiting
4
1467
 
EpiNet Study Group, Health Research Council of New Zealand, Neurological Foundation of New Zealand, Julius Brendel Trust
Epilepsy
 
 
ChiCTR-TRC-13003743: Anti-epilepsy drugs prophylaxis in cranioplasty for patients with skull defection: A prospective randomized controlled study

Completed
4
200
 
levetiracetam prophylaxis vs without levetiracetam prophylaxis
The First Affiliated Hospital of PLA General Hospital; Level of the institution:, Research funds
Epilepsy
 
 
2012-001884-64: A study of Standard and New Antiepileptic Drugs – SANAD-II.

Ongoing
4
1510
Europe
Sodium Valproate, Lamotrigine, Levetiracetam, Zonisamide, Tablet, Capsule, hard, Lamictal, Keppra, Zonegran
University of Liverpool, The Walton Centre NHS Foundation Trust, National Institute for Health Research (NIHR) Health Technology Assessment Program (HTA)
Epilepsy, Brain disorder, Diseases [C] - Nervous System Diseases [C10]
 
 
ChiCTR-OCC-11001874: Evaluate the efficacy and safety of Levetiracetam for prophylaxis and treatment of febrile seizure in children

Completed
4
67
 
NA ;starting dose with LEV 30mg/kg
PLA General Hospital; PLA General Hospital, NA
febrile seizure
 
 
2014-002188-13: Emergency treatment with levetiracetam or phenytoin in status epilepticus in children (EcLiPSE) - a randomsied unblinded controlled trial

Ongoing
4
308
Europe
Levetiracetam, Phenytoin, Concentrate for solution for infusion, Keppra, Epanutin
University of Liverpool, Alder Hey Children's NHS Foundation Trust, National Institute Health Research Health Technology Assessment (NETSCC), ational Institute Health Research Health Technology Assessment (NETSCC)
Convulsive Status Epilepticus, A convulsive seizure which continues for a prolonged period (longer than five minutes), or when convulsive seizures occur one after the other with no recovery between., Diseases [C] - Nervous System Diseases [C10]
 
 
2004-002114-11: A double blind, randomized, placebo-controlled, cross-over study to evaluate the effects of Levetiracetam on membrane excitability properties of afferent myelinated and unmyelinated fibers and change in neuropathic pain in patients with painful traumatic nerve injury.

Ongoing
4
20
Europe
Levetiracetam, - Keppra 250mg, - Keppra 500mg, - Keppra 250mg, - Keppra 500mg
Infociencia Clinical Research
Neuropathic pain due to a traumatic nerve lesion
 
 
2005-001516-41: Efficacy and safety of Levetiracetam treatment in patients suffering from Restless Legs SyndromeEficacia y seguridad de un tratamiento con levetiracetam en pacientes con síndrome idiopático de piernas inquietas

Ongoing
4
12
Europe
Levetiracetam, Keppra 250, Keppra 500, Keppra 250, Keppra 500
Clínica Plató Fundació Privada
Restless legs syndrome (RLS)
 
 
2005-002042-19: Double-blind, placebo controlled cross-over study to assess the efficacy of Levetiracetam in paediatric and childhood non-epileptic myoclonusEstudio cruzado, aleatorizado, doble ciego controlado con placebo, para evaluar la eficacia del Levetiracetam en el tratamiento del mioclonus no epiléctico en pacientes pediátricos y adolescentes

Ongoing
4
20
Europe
Levetiracetam, Keppra 250 mg, Keppra 500 mg, Keppra 250 mg, Keppra 500 mg
Hospital Sant Joan de Déu
Non-epileptic myoclonus
 
 
2005-002041-40: Double-blind, placebo controlled cross-over study to assess efficacy of Levetiracetam in paediatric and childhood Tourette syndrome. Estudio cruzado, aleatorizado, doble ciego controlado con placebo, para evaluar la eficacia del Levetiracetam en el control de los tics de pacientes pediátricos y adolescentes con síndrome de Gilles de la Tourette

Ongoing
4
20
Europe
Levetiracetam, Keppra 250 mg, Keppra 500 mg, Keppra 250 mg, Keppra 500 mg
Hospital Sant Joan de Déu
Tourette syndrome
 
 
2005-002474-30: Influence of levetiracetam on gamma band activity in a group of epilepsy patientsEstudio sobre la influencia de levetiracetam en la actividad de las ondas gamma en pacientes con epilepsia

Ongoing
4
25
Europe
Levetiracetam, Keppra 500mg, Keppra 1000mg, Keppra 500mg, Keppra 1000mg
Hospital Ruber Internacional
Epilepsy with partial and/or generalized seizures
 
 
2005-003903-35: : The Role of Keppra in the Treatment of Tremor in Multiple Sclerosis

Ongoing
4
20
Europe
Keppra ®, Keppra 250mg, Keppra 500mg
Newcastle-upon-Tyne Hospitals NHS Trust
Multiple Sclerosis
 
 
2005-003411-75: Estudio sobre la utilización de levetiracetam en monoterapia en pacientes HIV-positivos con epilepsia

Ongoing
4
20
Europe
levetiracetam, ucb-L059, Keppra 500 / 1000 mg comprimidos con cubierta pelicular, Keppra 500 / 1000 mg comprimidos con cubierta pelicular
Fundación para la Investigación Biomédica del Hospital Clínico de San Carlos
Pacientes HIV-positivos con epilepsia
 
 
2008-000370-20: Evaluation of pharmacokinetic and pharmacodynamic interactions between escitalopram and drugs used for the treatment of bipolar disorders.

Ongoing
4
24
Europe
Lamotrigine, Gabapentin, Carbamazepine, Oxcarbazepine, Levetiracetam, Valproic acid, CIPRALEX, LITIO CARBONATO, CIPRALEX, LITIO CARBONATO
AZIENDA OSPEDALIERA PISANA
bipolar disorders
 
 
2011-005971-18: TTS (Time To Stop) Trial

Ongoing
4
40
Europe
carbamazepine, Levetiracetam, Lamotrigine, RVG 11401 (tabletten 100 mg), RVG 03899 (tabletten, RVG 29546, We won\'t be investigating a specific IMP but a group of antiepileptic drugs to be withdrawn earlier after epilepsy surgery. The earlier withdrawal is the research question. As discussed 3 IMPs wille be given; carbamazepine, Levetiracetam, Lamotrigine, We won\'t be investigating a specific IMP but a group of antiepileptic drugs to be withdrawn earlier after epilepsy surgery. The earlier withdrawal is the research question. As discussed 3 IMPs wille be given; carbamazepine, Levetiracetam, Lamotrigine
University Medical Center Utrecht, Dutch national epilepsy fund
We will investigate possible cognitive benifits of early antiepileptic drug withdrawal after pediatric epilepsy surgery. The concerning medical condition is refractory epilepsy
 
 
2015-004827-30: Rapid versus slow withdrawal of antiepileptci monotherapy in two-year seizure free patients. Sospensione rapida contro sospensione lenta della monoterapia con un farmaco antiepilettico in pazienti senza crisi da almeno due anni

Ongoing
4
350
Europe
Tablet, KEPPRA - 1000MG-COMPRESSA RIVESTITA CON FILM-USO ORALE BLISTER DIVISIBILE (ALLUMINIO/PVC)-100X1 (DOSE UNITARIA)
AZIENDA OSPEDALIERA "BIANCHI-MELACRINO-MORELLI", Ministero della Salute, REGIONE CALABRIA
Epilepsy Epilessia, Epilepsy Epilessia, Diseases [C] - Nervous System Diseases [C10]
 
 
2018-000781-10: EFFICACY AND TOLERABILITY OF LOW versus STANDARD DAILY DOSES OF ANTIEPILEPTIC DRUGS IN NEWLY DIAGNOSED, PREVIOUSLY UNTREATED EPILEPSY Efficacia e tollerabilit¿ di basse dosi contro dosi standard dei farmaci antiepilettici in pazienti non trattati di nuova diagnosi.

Not yet recruiting
4
374
Europe
CARBAMAZEPINA, OXCARBAZEPINA, LAMOTRIGINA, LEVETIRACETAM, TOPIRAMATO, ACIDO VALPROICO, GABAPENTIN, ZONISAMIDE, CARBAMAZEPINA BASSA DOSE, OXCARBAZEPINA BASSA DOSE, LAMOTRIGINA BASSA DOSE, LEVETIRACETAM BASSA DOSE, TOPIRAMATO BASSA DOSE, ACIDO VALPROICO BASSA DOSE, GABAPENTIN BASSA DOSE, ZONISAMIDE BASSA DOSE, CARBAMAZEPINA, OXCARBAZEPINA, LAMOTRIGINA, LEVETIRACETAM, TOPIRAMATO, ACIDO VALPROICO, GABAPENTIN, ZONISAMIDE, CARBAMAZEPINA BASSA DOSE, OXCARBAZEPINA BASSA DOSE, LAMOTRIGINA BASSA DOSE, LEVETIRACETAM BASSA DOSE, TOPIRAMATO BASSA DOSE, ACIDO VALPROICO BASSA DOSE, GABAPENTIN BASSA DOSE, ZONISAMIDE BASSA DOSE, Tablet, Capsule, hard, TEGRETOL - 200 MG COMPRESSE A RILASCIO MODIFICATO 30 COMPRESSE, TOLEP - 300 MG COMPRESSE 50 COMPRESSE DIVISIBILI, LAMOTRIGINA DOC - 100 MG COMPRESSE DISPERSIBILI 56 COMPRESSE IN BLISTER ACLAR/PVC/AL, LEVETIRACETAM DOC - 500 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE, TOPIRAMATO DOC GENERICI - 100 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE IN BLISTER AL/AL, ACIDO VALPROICO SANDOZ - 300 MG COMPRESSE A RILASCIO PROLUNGATO30 COMPRESSE, GABAPENTIN MYLAN GENERICS - 400 MG CAPSULE RIGIDE 500 (5X100) CAPSULE IN BLISTER PVC/ALU CONFEZIONE OSPEDALIERA, ZONEGRAN - 100 MG CAPSULA RIGIDA USO ORALE BLISTER (PVC/ALL) 196 CAPSULE
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI, Ministero della Salute, Regione Lombardia
EPILEPSY EPILESSIA, EPILEPSY EPILESSIA, Diseases [C] - Nervous System Diseases [C10]
 
 
ChiCTR-IPR-15007241: Intermittent oral levetiracetam preventing the recurrence of febrile seizure with epileptiform discharges under the monitoring of iThermonitor: a multicenter randomized controlled trail

Not yet recruiting
4
400
 
LEV 15-30mg/kg ;NA
Chinese PLA General Hospital; PLA General Hospital, NA
febrile seizure
 
 
ACTRN12615000556549: EpiNet-First Trial 2: Comparison of efficacy of levetiracetam and sodium valproate in people with previously untreated epilepsy who have generalised seizures.

Terminated
4
506
 
EpiNEt Study Group, Health Research Council of New Zealand;, Neurological Foundation of New Zealand, Julius Brendel Trust
Epilepsy
 
 
ACTRN12615000641594: EpiNet-First Trial 5: Comparison of efficacy of levetiracetam and lamotrigine in people with previously untreated epilepsy who have unclassified seizures, and for whom sodium valporate is not deemed an acceptable anti-epileptic drug.

Terminated
4
664
 
EpiNet Study Group, Health Research Council of New Zealand, Neurological Foundation of New Zealand, Julius Brendel Trust
Epilepsy
 
 
ACTRN12615000640505: EpiNet-First Trial 4: Comparison of efficacy of levetiracetam, lamotrigine and sodium valproate in people with previously untreated epilepsy who have unclassified seizures.

Terminated
4
1176
 
EpiNet Study Group, Health Research Council of New Zealand, Neurological Foundation of New Zealand, Julius Brendel Trust
Epilepsy
 
 
ACTRN12615000639527: EpiNet-First Trial 3: Comparison of efficacy of levetiracetam and lamotrigine in people with previously untreated epilepsy who have generalised seizures, and for whom sodium valporate is not deemed an acceptable anti-epileptic drug.

Terminated
4
664
 
EpiNet Study Group, Health Research Council of New Zealand, Neurological Foundation of New Zealand, Julius Brendel Trust
Epilepsy
 
 
NCT04829838: Comparison of Efficacy of Phenytoin With Levetireacetam for the Management of Children With Status Epilepticus

Recruiting
4
244
RoW
intravenous levetireacetam
ayesha tariq, King Edward Medical University
Status Epilepticus
07/21
07/21
ChiCTR2200057041: Cost-effectiveness analysis of domestic and imported levetiracetam tablets in the treatment of children with focal epilepsy (real world study)

Not yet recruiting
4
80
 
Domestic levetiracetam treatment ;Imported levetiracetam treatment
Beijing Children's Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, none
Focal epilepsy in children
 
 
ChiCTR2000030052: A single prospective randomized controlled clinical trial of antiepileptic drug regimen for glioma patients with non-preoperative epilepsy

Not yet recruiting
4
100
 
take levetiracetam for 1 week ;take levetiracetam for 4 weeks
Beijing Tiantan Hospital, Capital Medical University; Beijing Tiantan Hospital, Capital Medical University, Beijing Natural Science Foundation
Glioma related epilepsy
 
 
ChiCTR2000030228: A single prospective randomized controlled clinical trial for antiepileptic drug regimen in the treatment of patients with glioma-related epilepsy

Not yet recruiting
4
100
 
levetiracetam for 6 months ;levetiracetam for 12 months
Beijing Tiantan Hospital, Capital Medical University; Beijing Tiantan Hospital, Capital Medical University, Beijing Natural Science Foundation
Glioma-related epilepsy
 
 
NCT06403150: The Efficacy and Safety of Levetiracetam Versus Fosphenytoin in Convulsive Status Epilepticus

Enrolling by invitation
4
62
RoW
Levetiracetam Injection, Iracet Injection, Neurocet Injection, Fosphenytoin Injection, Fosfen Injection
Dhaka Medical College
Status Epilepticus
08/24
10/24
2020-004878-22: Pharmacokinetic and Placental Transfer of Levetiracetam Etude de la pharmacocinétique maternelle et du passage transplacentaire du Lévétiracétam

Not yet recruiting
4
50
Europe
Film-coated tablet
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, DGOS
Epilepsy in pregnancy l'épilepsie pendant la grossesse, Epilepsy in pregnancy l'épilepsie pendant la grossesse, Diseases [C] - Nervous System Diseases [C10]
 
 
SPAR, NCT01801072: Seizure Prophylaxis in Aneurysm Repair

Completed
4
82
US
Levetiracetam, Keppra
University of Michigan
Intracranial Aneurysms, Seizure
10/23
10/23
GENESIS, NCT04759196: Generating Evidence on NonEpileptic, Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hematomas

Recruiting
4
56
Canada
Topamax, Topiramate, TPM, Levetiracetam, LEV, Keppra
Université de Sherbrooke
Chronic Subdural Hematoma, Epilepsy; Seizure, Cortical Depression; Cortical Depolarization, Nonepileptic, Stereotypical and Intermittent Symptoms, NESIS
09/24
12/24
NCT06081283: Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Active, not recruiting
4
54
US
Phenobarbital Sodium Injection, phenobarbital, Levetiracetam, Lacosamide Injectable Product, Valproate Sodium, Valproate, Phosphenytoin
University of North Carolina, Chapel Hill
Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia, Hypoxia-Ischemia, Brain, Heart Arrest, Stroke, Intracranial Hemorrhages, Coma, Persistent Vegetative State
01/25
04/25
SEIZE-TBI, NCT06866691: Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

Not yet recruiting
4
600
US
levetiracetam, Keppra, lacosamide, Vimpat
Wake Forest University Health Sciences
Traumatic Brain Injury
04/26
04/26
NCT05969054: Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy

Recruiting
4
140
RoW
Lacosamide 100 mg, Levetiracetam 250mg
Xiangya Hospital of Central South University
Alzheimer Disease 3, Epilepsy
12/25
12/25
STING, NCT03048084: Seizure Treatment in Glioma

Recruiting
4
120
Europe
Levetiracetam, Keppra, Valproic Acid, Depakine
Leiden University Medical Center, Medical Center Haaglanden, Erasmus Medical Center, Amsterdam UMC, location VUmc
Glioma
07/26
07/28
NCT05737511: Efficacy of Hydroxyzine for Patients With Panic Disorder

Not yet recruiting
4
80
NA
Hydroxyzine, Atarax, Vistaril, Escitalopram Oxalate, citalopram, fluoxetine, fluvoxamine, paroxetine, paroxetine CR, sertraline, venlafaxine XR,, Alprazolam, clomipramine, clonazepam, diazepam, imipramine, lorazepam, mirtazapine, reboxetine, Bupropion SR, divalproex, duloxetine, gabapentin, levetiracetam, milnacipran, moclobemide, olanzapine, phenelzine, quetiapine, risperidone, tranylcypromine
Sultan Qaboos University
Panic Disorder
12/26
12/26
2005-001776-13: Efficacy of Levetiracetam in the treatment of spasticity in MS: a ranomized double blind cross over study

Ongoing
3
24
Europe
Levetiracetam,
Organisation name was not entered
Multiple Sclerosis
 
 
2007-005414-40: Efficacy and activity of levetiracetam on Multiple Sclerosis cerebellar symptoms: a multicenters double blind, randomized, placebo-controlled, cross over study

Ongoing
3
60
Europe
KEPPRA, KEPPRA
AZIENDA SANITARIA N. 3 GENOVESE
Patients with an established and stable Multiple Sclerosis (according to Poser criteria).
 
 
2018-001312-30: Investigating the use of levetiracetam to prevent seizures after brain surgery.

Not yet recruiting
3
804
Europe
Keppra, ucb 22059, Tablet, Keppra
Common Services Agency
Seizures in patients with suspected cerebral glioma, Seizures in patients with suspected primary brain tumour, Diseases [C] - Cancer [C04]
 
 
PEACH, NCT03340064 / 2021-003372-13: A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging From 1 Month to Less Than 4 Years of Age

Completed
3
38
Japan
Levetiracetam, Keppra, E-Keppra, LEV
UCB Japan Co. Ltd., UCB Japan Co. Ltd.
Partial Seizures
06/21
07/23
2021-003392-34: Aggressive or less aggressive treatment of persistent epileptic seizures

Ongoing
3
140
Europe
Briviracetam, e.g. Keppra, e.g. Topimax, e.g. orfiril, Vimpat, n.a. many producers, different producers, Concentrate and solvent for solution for infusion, Infusion, Tablet, Briviract, Levetiracetam, Fosfenytoin, Topriamate, Orfiril/valproic acid, Vimpat, Propofol, Midazolam
Odense Universitetshospital, In-house funding Odense University Hospital
Verfied non convulsive status epilepticus refractory to standard treatment with benzodiazepines and at least one first line drug, Persistent epileptic seizures that do not respond to standard treatment, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT05722951: Metformin Efficacy and Safety in Epileptic Patients

Completed
3
60
RoW
Levetiracetam &/or sodium valproate, Levetiracetam &/or valproic acid, Metformin
Tanta University
Epilepsy
06/24
06/24
2021-003372-13: A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging from 1 Month to Less Than 4 Years of Age

Not yet recruiting
3
48
Japan
Solution for infusion, Powder for syrup, E Keppra® for I.V. infusion 500 mg, E Keppra® Dry Syrup 50%
UCB Japan Co. Ltd., UCB Japan Co. Ltd.
Partial Seizures, A partial seizure is a seizure which occurs in just one area of the brain., Diseases [C] - Nervous System Diseases [C10]
 
 
LeviTaTe Pilot, NCT05897658: Levetiracetam Prophylaxis in Brain Tumor Resection Pilot

Not yet recruiting
3
70
NA
Levetiracetam, Placebo
Hamilton Health Sciences Corporation, McMaster University
Seizures, Brain Tumor
03/26
03/26
LIBRA, NCT06442748: Short Versus Long-term Levetiracetam in Brain Tumors

Recruiting
3
604
RoW
Levetiracetam
Tata Memorial Centre
Seizures, Brain Tumors, Antiepileptics, Levetiracetam
06/31
06/31
KISS, NCT06851078: Evaluation of Early Administration of Levetiracetam in the Prevention and Treatment Encephalopathy in Septic Shock: Randomized, Double-blind, Placebo-controlled Trial

Not yet recruiting
3
280
NA
Levetiracetam IV, Placebo control
Assistance Publique - Hôpitaux de Paris
Septic Shock
06/27
06/27
EAST, NCT06773364: Early Initiated Ambulance-delivered Levetiracetam and Headposition in Hyper-acute Stroke Trial

Not yet recruiting
3
2423
NA
Levetiracetam, Guide-recommended management, The lying flat (0°) head position, The sitting-up (≥30°) head position
Shanghai East Hospital
Suspected Stroke
12/28
12/29
MAST, NCT04573803: Pharmacological Management of Seizures Post Traumatic Brain Injury

Not yet recruiting
3
1649
NA
Phenytoin Sodium, Levetiracetam, Keppra
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge
Traumatic Brain Injury, Post Traumatic Seizures
03/26
03/28
2008-001098-13`ACTRN12617001195347: Simultaneous administration of lorazepam and levetiracetam in non-convulsive status epilepticus, followed by IV valproate: a prospective, randomized, placebo-controled, double-blind pilot trial.

Ongoing
2
80
Europe
LEVETIRACETAM, L059, KEPPRA®, KEPPRA®
UZ Leuven, Department of Health, Western Australia
Peanut allergy
 
 
2020-003698-24: A study to investigate JNJ-40411813 in combination with levetiracetam in epilepsy

Ongoing
2
112
Europe
JNJ-40411813, JNJ-40411813, Tablet
Janssen-Cilag International NV, Janssen Research and Development LLC, US
Focal Onset Seizures, Seizures, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT01857934: Therapy for Children With Advanced Stage Neuroblastoma

Active, not recruiting
2
153
US
cyclophosphamide, Cytoxan(R), topotecan, Hycamtin(R), hu14.18K322A, humanized anti-GD2 antibody, monoclonal antibody, dinutuximab, peripheral blood stem cell harvest, PBSCH, surgical resection, cisplatin, Platinol-AQ(R), etoposide, VP16, Vepesid(R), Etopophos(R), doxorubicin, Adriamycin(R), vincristine, Oncovin(R), busulfan, Busulfex(R), melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, Alkeran(R), peripheral blood stem cell transplantation, PBSCT, natural killer cell infusion, NK cell infusion, radiation therapy, GM-CSF, sargramostim, Leukine(R), granulocyte macrophage colony stimulating factor, G-CSF, Granulocyte colony stimulating factor, Neupogen(R), Filgrastim, mesna, Mesnex(R), levetiracetam, Keppra, interleukin-2, IL-2, aldesleukin, Proleukin(R), Isotretinoin, 13-cis retinoic acid, CliniMACS, Cell Selection System
St. Jude Children's Research Hospital, Cookies for Kids' Cancer, CURE Childhood Cancer, Inc.
Neuroblastoma
10/21
12/25
LEVNEONAT-1, NCT02229123 / 2014-000791-26: Levetiracetam Treatment of Neonatal Seizures: Safety and Efficacy Phase II Study

Completed
2
18
Europe
Intravenous Levetiracetam
University Hospital, Tours, Assistance Publique - Hôpitaux de Paris, Rennes University Hospital, Amiens University Hospital
Neonatal Seizures
02/22
02/22
ILiAD, NCT03489044 / 2016-003109-32: An Investigation of Levetiracetam in Alzheimer's Disease

Completed
2
8
Europe
Levetiracetam, Placebo Oral Tablet
University of Oxford, Oxford University Hospitals NHS Trust, Oxford Health NHS Foundation Trust, Northumberland, Tyne and Wear NHS Foundation Trust, UCB Pharma
Alzheimer Disease, Epilepsy
03/22
03/22
TRIP, NCT04643327: Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease

Recruiting
2
28
RoW
Levetiracetam, Placebo
The University of Queensland, Queensland University of Technology, Johns Hopkins University, Cleveland Clinic Lou Ruvo Center for Brain Health, Royal Brisbane and Women's Hospital
Parkinson Disease, Mild Cognitive Impairment, Memory Impairment
01/25
12/25
NCT03875638: Treating Hyperexcitability in AD With Levetiracetam

Recruiting
2
85
US
Levetiracetam, Placebo oral capsule
Beth Israel Deaconess Medical Center
Alzheimer Dementia, Alzheimer Disease, Dementia of Alzheimer Type, Mild Cognitive Impairment
10/25
11/25
NCT04317807: R33: Levetiracetam in Early Psychosis

Recruiting
2
84
US
Levetiracetam Pill, Keppra, Placebo
NYU Langone Health
Early Psychosis
01/25
01/25
NCT04836559 / 2020-003698-24: A Study to Investigate JNJ-40411813 in Combination With Levetiracetam or Brivaracetam in Epilepsy

Completed
2
110
Europe, US, RoW
JNJ-40411813, Placebo
Janssen Research & Development, LLC, Janssen Research and Development LLC, US
Focal Onset Seizures
02/24
02/24
NCT06345495: High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

Recruiting
2
30
US
Ruxolitinib, Jakafi, INCB018424, INC424, Allogeneic Stem Cell Transplantation, Autologous stem cell transplant, Cord Blood, Levetiracetam, Eltrombopag, Promacta®, Busulfan, Busulfex™, Myleran®, Romiplostim, AMG 531, Nplate, Fludarabine phosphate, Fludarabine, Fludara®, Cyclophosphamide, Cytoxan®, Neosar®, Mesna, Mesnex™, Tacrolimus, Prograf®
M.D. Anderson Cancer Center, Incyte Corporation
Splenomegaly, Myelofibrosis
01/27
01/29
LAPSE, NCT04004702: Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial

Not yet recruiting
2
65
US
Levetiracetam, Keppra
Walter Reed National Military Medical Center
Alzheimer Disease
12/24
06/25
NCT04559529: Pharmacological Modulation of Hippocampal Activity in Psychosis 2

Completed
2
62
US
Levetiracetam (LEV) 500 mg, Keppra, Placebo
Vanderbilt University Medical Center
Schizophrenia; Psychosis
12/23
12/23
NEOLEV3, NCT05610085: A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures

Recruiting
2
133
US, RoW
Levetiracetam Injection, Phenobarbital Sodium Injection
University of California, San Diego, University of Minnesota, Rady Children's Hospital, San Diego, Auckland City Hospital, University of Auckland, New Zealand, Middlemore Hospital, New Zealand
Neonatal Seizure, Neonatal Encephalopathy, Hypoxic-Ischemic Encephalopathy, Seizure Newborn
07/27
12/27
NCT05735717: MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Recruiting
2
150
US
Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam, Keppra
Masonic Cancer Center, University of Minnesota
Hematologic Malignancy, Acute Leukemia, Remission, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, AML, TP53, Intrachromosomal Amplification of Chromosome 21, Cytogenetic Abnormality, CNS Leukemia, Minimal Residual Disease, Myelodysplasia, Juvenile Myelomonocytic Leukemia, Somatic Mutation, PTPN11 Gene Mutation, N-RAS Gene Amplification, Neurofibromatosis 1, NF1 Mutation, CBL Gene Mutation, Monosomy 7, Chromosome Abnormality, Fetal Hemoglobin
11/27
11/30
2006-006804-12: Levetiracetam (Keppra®) in neonates

Ongoing
1/2
10
Europe
Keppra, Keppra
ErasmusMedical Center-Sophia
epileptic seizures in neonates admitted to the intensive care unit
 
 
NCT02602015: Levetiracetam Treatment of Neonatal Seizures

Not yet recruiting
1/2
100
RoW
Oral levetiracetam, Keppra, Intravenous phenobarbital, phenobarbitone
The People's Hospital of Dehong Autonomous Prefecture, Children's Hospital of Fudan University, Xiamen Children's Hospital, Fujian of China, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Guangzhou Women and Children's Medical Center, Second Affiliated Hospital of Wenzhou Medical University, Maternal and Child Health Hospital of Hubei Province
Neonatal Seizures
12/18
12/18
ZUMA-1, NCT02348216 / 2015-005007-86: Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma

Checkmark Data from ZUMA-1 trial for R/R LBCL at ASH 2022
Dec 2022 - Dec 2022: Data from ZUMA-1 trial for R/R LBCL at ASH 2022
Checkmark Presentation from ZUMA-1 trial for DLBCL at ASTCT 2021
Feb 2021 - Feb 2021: Presentation from ZUMA-1 trial for DLBCL at ASTCT 2021
Checkmark Presentation from ZUMA-1 trial for DLBCL at ASH 2020
More
Completed
1/2
307
Europe, Canada, US, RoW
Axicabtagene Ciloleucel, Yescarta®, Fludarabine, Cyclophosphamide, Levetiracetam, Tocilizumab, Dexamethasone, High-dose methylprednisolone, Bendamustine, Rituximab, Doxorubicin, Prednisone, Vincristine, Ifosfamide, Carboplatin, Etoposide, Gemcitabine, Oxaliplatin, Cisplatin, Methylprednisolone
Kite, A Gilead Company
Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B-Cell Lymphoma, Transformed Follicular Lymphoma (TFL), Primary Mediastinal B-cell Lymphoma (PMBCL), High Grade B-cell Lymphoma (HGBCL)
07/23
07/23
NCT04497142: Effect of Perampanel on Peritumoral Hyperexcitability in HGG

Completed
1/2
12
US
Perampanel, E2007, Fycompa, Standard of Care, Standard treatment (typically the anti-seizure medication levetiracetam)
Dana-Farber Cancer Institute, National Cancer Institute (NCI), Eisai Inc.
Glioma, Malignant, Surgery, Seizures
05/23
05/23
CAN-GT, NCT04833907: rAAV-Olig001-ASPA Gene Therapy for Treatment of Children With Typical Canavan Disease

Recruiting
1/2
24
US
rAAV-Olig001-ASPA, MYR-101, Levetiracetam, Keppra, Prednisone
Myrtelle Inc.
Canavan Disease
08/26
08/27
NCT03034356: Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia

Completed
1/2
67
US
Levetiracetam, Keppra, Placebo
VA Office of Research and Development
Schizophrenia
06/24
06/24
NCT02550028: Levetiracetam Treatment of Neonatal Seizures

Terminated
1/2
60
RoW
Oral levetiracetam, Keppra, Intravenous phenobarbital, phenobarbitone
Children's Hospital of Fudan University, Xiamen Children's Hospital, Fujian of China, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Guangzhou Women and Children's Medical Center, Second Affiliated Hospital of Wenzhou Medical University, Maternal and Child Health Hospital of Hubei Province, The Maternal & Children Health Hospital of Dehong, Yunnan of China
Neonatal Seizures
01/17
01/17
ChiCTR2000032328: Human bioequivalence test of levetiracetam injection

Completed
1
24
 
levetiracetam injection versus levetiracetam tablet
Peking University First Hospital; Sichuan Dingnuo Taichen Technology Co., Ltd., Sichuan Dingnuo Taichen Technology Co., Ltd.
epilepsy
 
 
NCT00227461: Levetiracetam (Keppra) to Improve Chronic Aphasia in Post-stroke Patients.

Active, not recruiting
1
50
US
Wait first, then levetiracetam, Keppra, Levetiracetam first, then wait
Kessler Foundation, UCB Pharma
Aphasia, Stroke
12/21
12/21
ACTRN12624001326583: Efficacy of levetiracetam versus phenytoin in children with convulsive status epilepticus, Single blinded Randomized controlled trial

Not yet recruiting
N/A
134
 
Dr Hina Parvaiz- Medical Teaching Institute Lady Reading Hospital Peshawar
Status epilepticus
 
 
ACTRN12623001032640: The ALLEVIATE study. A prospective observational comparative plasma and cerebrospinal fluid pharmacokinetics study of levetiracetam in aneurysmal subarachnoid haemorrhage and traumatic brain injury.

Recruiting
N/A
40
 
The University of Queensland, Royal Brisbane and Women's Hospital & RBWH Foundation Project Grant
traumatic brain injury, aneurysmal subarachnoid haemorrhage
 
 
ChiCTR1800015004: Bioequivalence study of Levetiracetam Tablets in Healthy Chinese Volunteers

Recruiting
N/A
48
 
RT in fasted states ;TR in fasted states ;RT in fed states ;TR in fed states
First Affiliated Hospita, College of Medicine, Zhejiang University; ZHEJIANG JINGXIN PHARMACEUTICAL CO., LTD., ZHEJIANG JINGXIN PHARMACEUTICAL CO.,LTD.
Healthy Volunteers
 
 
ChiCTR2000031542: The effects of selective dorsal root rhizotomy in children with spastic cerebral palsy

Completed
N/A
90
 
selective dorsal root rhizotomy and levetiracetam ;routine rehabilitation and levetiracetam ;levetiracetam
The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital; China National Nuclear Corporation 416 Hospital Ethics Committee, the health planning committee of Sichuan Foundation Project
children with spastic cerebral palsy
 
 
ChiCTR1900028636: Effect of pregabalin monotherapy on sleep in patients with epilepsy

Completed
N/A
60
 
pregabalin; levetiracetam
The First Hospital of Shanxi Medical University; The First Hospital of Shanxi Medical University, Funding support for Shanxi Province key R & D plan (international cooperation) project
epilepsy
 
 
ChiCTR1900028463: Study for comparison of levetiracetam and oxcarbazepine/Sodium valproate monotherapy among infants with newly diagnosed focal epilepsy

Recruiting
N/A
300
 
oxcarbazepine ;levetiracetam ;Sodium valproate
Children's Hospital, Chongqing Medical University; Children's Hospital, Chongqing Medical University, self-financing
focal epilepsy in infants
 
 
NCT02866877: Effects of Augmented Renal Clearance on Pharmacokinetic and Pharmacodynamic Properties of Levetiracetam in Subarachnoid Hemorrhage

Completed
N/A
15
US
Pharmacokinetic modeling
University of Colorado, Denver
Subarachnoid Hemorrhage
06/19
03/21
ChiCTR2100050276: Pilot study to evaluate the bioequivalence of levetiracetam extended-release tablets in healthy subjects

Recruiting
N/A
32
 
the reference preparation was given on an empty stomach in large size ;the test preparation was given on an empty stomach in large size ;the reference preparation was given on an empty stomach in small size ;the test preparation was given on an empty stomach in small size ;the reference preparation was given after meals in large size ;the test preparation was given after meals in large size ;the reference preparation was given after meals in small size ;the test preparation was given after meals in small size
Dongyang Hengdian Hospital; Dongyang Hengdian Hospital, Hangzhou Bio-Sincerity Pharma-Tech Co., Ltd.
Pharmacokinetic study
 
 
LEVAGE, NCT06393309: Levetiracetam Versus Valproate in Idiopathic Generalized Epilepsy

Completed
N/A
169
RoW
Levetiracetam, Sodium valproate
Mazandaran University of Medical Sciences
Treatment of Idiopathic Generalized Epilepsy
03/24
03/24
levcbz, NCT06138847: Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy?

Active, not recruiting
N/A
119
RoW
electroencephalogram
İpek Dokurel
Epilepsy; Syndrome, Seizures of Localized Onset
08/23
12/23
NCT06067412: Efficacy of Phenytoin vs Levetiracetam in Status Epilepticus at Institute of Child Health,Faisalabad

Completed
N/A
70
RoW
Levetiracetam, Phenytoin
Shaheed Zulfiqar Ali Bhutto Medical University
Status Epilepticus
01/23
01/23
EPICEINTE, NCT04117425: Pharmacokinetic and Placental Transfer of Levetiracetam

Recruiting
N/A
50
Europe
biological collection
Assistance Publique - Hôpitaux de Paris
Epilepsy in Pregnancy
06/23
09/23
NCT04939675: Modification of Epilepsy Screen Questionnaire and Treatment Feasibility Evaluation

Not yet recruiting
N/A
40
NA
Zonisamide 100mg, Zonegran 100mg, Levetiracetam 500mg, Keppra 500mg, LamoTRIgine 50mg, Lamictal 50mg
National Taiwan University Hospital
Epilepsy
06/23
06/25
ChiCTR1800016975: Short-course prevention of febrile seizures in children: A Prospective, Multi-Center, and Real-World study

Recruiting
N/A
6000
 
without intervention ;Oral diazepam at the early stage of fever to prevent febrile seizure, 0.3mg/kg (Max≤10 mg), q8h (≤3 times in 24h) ;oral Levetiracetam after the first episode, 15-30mg/(kg.d), bid, for 3-5 days
The Second Affiliated Hospital of Shantou University Medical College (Department of Pediatrics); The Second Affiliated Hospital of Shantou University Medical College, Patients own expense on necessary medical care
febrile seizures(FS)
 
 
NCT04858841: Post-stroke Epilepsy: Primary Prophylaxis Study

Recruiting
N/A
180
RoW
Levetiracetam Oral Product, keppra, Perampanel Oral Product, fycompa, Placebo
National Cheng Kung University, Ministry of Science and Technology, Taiwan, National Cheng-Kung University Hospital
Middle Cerebral Artery Stroke
07/23
07/23
SUPER-CAT, NCT05756621: Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest

Recruiting
N/A
80
Europe
Ketamine, Perampanel, Any anti-epileptic and anesthetic therapy, excluding Ketamine and Perampanel, Levetiracetam, Valproate, Phenytoin, Lacosamide, Topiramate, Propofol, Midazolam, Thiopental
University of Milano Bicocca, Azienda Ospedaliera San Gerardo di Monza, Azienda Ospedaliero-Universitaria di Modena, Azienda Ospedaliera Universitaria Integrata Verona, Ospedale Centrale Bolzano, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Azienda Ospedaliero-Universitaria Careggi, Azienda Ospedaliero-Universitaria di Parma, Santa Chiara Hospital, Ospedale M. Bufalini Cesena, Azienda Ospedaliera Brotzu, Istituto Di Ricerche Farmacologiche Mario Negri
Status Epilepticus, Cardiac Arrest
03/25
03/25
LEVET, NCT06498362: The "New" Place of IRACETAM in the Management of Status Epilepticus in Children

Recruiting
N/A
151
Europe
University Hospital, Strasbourg, France
Epilepsy in Children
05/25
05/25
NCT02647437: Effects of Low-dose Levetiracetam on Clinical Symptoms, Cognition and Hippocampal Hyperactivity in Schizophrenia

Recruiting
N/A
30
US
Levetiracetam, Keppra, Placebo
University of Colorado, Denver
Schizophrenia
06/24
06/24
NCT05543122: Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants

Completed
N/A
39
Canada
either of Atenolol, Bupropion, Brivaracetam, Escitalopram, Fluconazole, Lacosamide, Lamotrigine, Levetiracetam, Methotrexate or Ezetimibe, Typical brand names include, but not limited to: Tenoretic, Wellbutrin, Zyban, Briviact, Cipralex, Lexapro, Diflucan, Vimpat, Lamictal, Keppra, Trexall, Xatmep, Ezetrol, Nexlizet
The Hospital for Sick Children, St. Justine's Hospital, University of Waterloo
Breast Feeding
12/23
03/24
NCT06181383: Phenobarbital Versus Levetiracetam Neonatal Convulsion

Not yet recruiting
N/A
42
NA
Assiut University
Neonatal Convulsion
11/24
05/25
ChiCTR2100041861: Clinical application of nocturnal high-dose levetiracetam in the treatment of BECT

Recruiting
N/A
90
 
2 hours before going to bed at night, 3 doses for 2 stroke and 3 doses for 1 stroke in the morning. ;The total dose should be taken at a time of 2 hours before going to bed at night. ;The total dose was divided into two parts, one hour before bedtime and one dose in the morning, with an interval of 12 hours.
West China Second University Hospital, Sichuan University; West China Second University Hospital, Sichuan University, Clinical Research Foundation of West China Second Hospital of Sichuan University-KL072
Benign childhood epilepsy with centro-temporal spikes, BECT
 
 
ChiCTR2000041512: Clinical application of nocturnal high-dose antiepileptic drugs in the treatment of BECT

Recruiting
N/A
240
 
levetiracetam ;oxcarbazepine ;levetiracetam ;oxcarbazepine
West China Second Hospital of Sichuan University; West China Second Hospital of Sichuan University, KL072
Benign childhood epilepsy with centro-temporal spikes, BECT
 
 
NCT05860153: Intermittent Levetricetam in Treatment of Febrile Convulsions

Not yet recruiting
N/A
100
NA
Levetiracetam, Tiratam, Diazepam, Valinil
Assiut University
Febrile Convulsion
01/24
08/24
NCT01666080: Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

Recruiting
N/A
30
US
Busulfan, Busulfex, Fludarabine, Fludara, Total body irradiation, Stem cell transplant, Keppra, Levetiracetam
Masonic Cancer Center, University of Minnesota
Hematologic Disorders, Hemoglobinopathies, Immunodeficiencies
06/25
06/25
LEVHIPPRO, NCT06224530: Investigating the Effect of a Single-dose of Levetiracetam on Brain Function, Chemistry and Cognitive Performance in Psychosis Risk

Recruiting
N/A
69
Europe
Levetiracetam, Keppra, Placebo
King's College London
Psychosis
02/26
02/26
ChiCTR2200059080: A randomized, controlled, multicenter clinical study evaluating the efficacy and safety of perampanel versus levetiracetam monotherapy in newly diagnosed focal epilepsy greater than or equal to 12 years of age

Not yet recruiting
N/A
200
 
Oral perampanel ;Oral Levetiracetam
The Seventh Affiliated Hospital, Sun Yat-Sen University; The Seventh Affiliated Hospital, Sun Yat-Sen University, China Association Against Epilepsy
Epilepsy
 
 
NCT03511118: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting
N/A
1600
Canada, US
Tranexamic acid (TXA), labetalol, metformin, nifedipine, clindamycin, oxycodone, azithromycin, escitalopram, sertraline, ondansetron, Ciprofloxacin, Doxycycline, Levofloxacin, Methylphenidate, Sumatriptan, Citalopram, Cyclobenzaprine, Furosemide, Gabapentin, Hydrochlorothiazide, Hydroxyurea, Rosuvastatin, Topiramate, Trazodone, Valganciclovir, Venlafaxine, Verapamil, Remdesivir, Anakinra, Tocilizumab, Fluvoxamine, Amoxicillin, Bupropion, Duloxetine, Hydrocodone, Levetiracetam, Paroxetine, Buprenorphine
Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
07/26
07/27
NCT06491303: Effects of Levetiracetam Monotherapy on Various Hematological Parameters in Adult Patients Suffering of Epilepsy

Not yet recruiting
N/A
45
NA
Assiut University
Neutropenia, Thrombocytopenia, Aplastic Anemia, Anemia, Epilepsy
11/25
12/25
BDE, NCT05450822: Precision Medicine in the Treatment of Epilepsy

Recruiting
N/A
550
Europe
Levetiracetam, [11C]-UCB-J PET-MR scan, Levetiracetam Tablets, Lamotrigine tablet, Lamotrigine
Gitte Moos Knudsen
Epilepsy
12/26
12/31
 

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