levetiracetam / Generic mfg. 
Welcome,         Profile    Billing    Logout  
 185 Diseases   81 Trials   81 Trials   6476 News 


«12...4950515253545556575859...8182»
  • ||||||||||  Trileptal (oxcarbazepine) / Novartis
    [VIRTUAL] Women with Epilepsy and Postpartum Toxicity: A Retrospective Analysis () -  Mar 18, 2021 - Abstract #AAN2021AAN_840;    
    Pregnant WWE on LTG may benefit from careful postpartum clinical management, LTG dose reduction, and education. Further research is needed to define the best clinical practices for ASD modifications during postpartum care.
  • ||||||||||  Vimpat (lacosamide) / UCB, Daiichi Sankyo
    [VIRTUAL] Alternating Seizure Focus In Mitochondrial Disease () -  Mar 18, 2021 - Abstract #AAN2021AAN_834;    
    Migrating imaging lesions are a known feature of MELAS commonly caused by the A3243G mutation. The prognosis of epilepsy in mitochondrial disease is poor.
  • ||||||||||  levetiracetam / Generic mfg.
    [VIRTUAL] Extreme Delta Brush: The Key to Anti-NMDA Receptor Encephalitis () -  Mar 18, 2021 - Abstract #AAN2021AAN_799;    
    Anti-NMDA-receptor encephalitis is a life-threatening condition that is treatable when diagnosed timely and immunosuppressive treatment is established promptly. Presence of EDB, although only present in a minority of patients, can streamline investigation and allow for rapid initiation of therapy.
  • ||||||||||  levetiracetam / Generic mfg., topiramate / Generic mfg.
    [VIRTUAL] The Rarest of The Rare: Late-Onset Pyridoxine Dependent Epilepsy in a Child () -  Mar 18, 2021 - Abstract #AAN2021AAN_713;    
    Literature surrounding atypical cases with a late onset is further sparse. While typically seen in neonates, this case shows that late onset PDE, especially after 2 years of age, must be considered in patients with intractable seizures or refractory status epilepticus without an underlying diagnosis, and especially in those unresponsive to conventional AEDs.
  • ||||||||||  lorazepam / Generic mfg.
    [VIRTUAL] A Stroke Alert With Unexpected Outcome: Thrombolytic Therapy And Intracranial Neoplasms () -  Mar 18, 2021 - Abstract #AAN2021AAN_464;    
    Our case suggests that thrombolysis inadvertently administered to a stroke mimic may be potentially safe in patients with high-grade gliomas and acceptable medical comorbidities and performance status. This underlines the need for further prospective studies for validation of this observation.
  • ||||||||||  levetiracetam / Generic mfg.
    [VIRTUAL] Phantosmia associated with Anti-Phospholipid Antibody Syndrome () -  Mar 18, 2021 - Abstract #AAN2021AAN_324;    
    It was postulated that these spells of phantosmia (olfactory aura / hallucination) were a part of the seizure semiology caused by autoimmune mediated pathology in APS which resolved with treatment. Conclusions : APS should be considered in the differentials for patients presenting with adult-onset seizures in the setting of SLE.
  • ||||||||||  levetiracetam / Generic mfg.
    [VIRTUAL] Cortical Venous Thrombosis as the Presenting Symptom of Hugh-Stovin Syndrome () -  Mar 18, 2021 - Abstract #AAN2021AAN_313;    
    It typically affects the young adult population with a statistical predilection for males. Although no formal diagnostic criteria have been formulated, the diagnosis of HSS is made when both venous thrombosis and multiple pulmonary and/or bronchial aneurysms are present.
  • ||||||||||  Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
    [VIRTUAL] Hyperammonemia in Critically Ill Patients, and Interplay of Pathophysiologic and Iatrogenic Factors () -  Mar 14, 2021 - Abstract #ATS2021ATS_4170;    
    Case Report: 76-year-old male with history of follicular lymphoma treated with R-CHOP was admitted to ICU one month after his most recent chemotherapy with sepsis and ruptured urinary bladder requiring intubation...Subsequently valproate was substituted with levetiracetam due to concern for worsening hyperammonemia, but unfortunately, he progressed to status epilepticus and ammonia level continued to worsen...Lactulose and rifaximin provide palliative treatment, by increasing gastrointestinal elimination and reducing gastrointestinal production of ammonia respectively, while we treat the underlying cause. Severe hyperammonemia (>200 µmol/L) with signs of cerebral edema or seizures should prompt emergent nephrology consultation and initiation of hemodialysis.
  • ||||||||||  levetiracetam / Generic mfg.
    [VIRTUAL] An Uncommon Cause of Acute Kidney Injury After Prolonged Seizure () -  Mar 14, 2021 - Abstract #ATS2021ATS_2723;    
    Neurology was consulted and he was treated with levetiracetam and monitored on a continuous Electroencephalogram...Evaluation of urine is quick and helps with diagnosis. This case emphasizes the significance of a timely diagnosis of an uncommon phenomenon and the importance of early interventions and administration of raspburicase to prevent irreversible kidney damage and progression to renal replacement therapy.
  • ||||||||||  carbamazepine / Generic mfg.
    [VIRTUAL] The Paradoxical Effect: Carbamazepine Overdose Leading to Seizures () -  Mar 14, 2021 - Abstract #ATS2021ATS_2519;    
    Case Presentation: This case describes a 36-year-old female who was found unconscious with empty bottles of Carbamazepine, Lamotrigine, Hydroxyzine, and Olanzapine...She was subsequently intubated for airway protection, given activated charcoal, and initiated on Propofol and Keppra given concerns for possible seizures...Treatment begins with stabilization of airway and breathing, and ranges from physiological clearance, use of activated charcoal, or extracorporeal therapy such as hemodialysis. This case highlights the serious neurological complications that accompanies severe carbamazepine toxicity, however, with early recognition and aggressive treatment, patients can have a favorable prognosis.
  • ||||||||||  levetiracetam / Generic mfg.
    [VIRTUAL] Consequences of Benadryl Overdose () -  Mar 14, 2021 - Abstract #ATS2021ATS_284;    
    ICU course was complicated with status epilepticus and she was started on Keppra for seizure control...This sets the stage for ventricular arrhythmias. This case highlights the importance of consideration of diphenhydramine overdose in cases of cardiac arrest after suspected toxic ingestion, particularly as this medication does not have a routine laboratory assay and is a rare occurrence.
  • ||||||||||  levetiracetam / Generic mfg.
    Journal:  Assessment of a white matter reference region for C-UCB-J PET quantification. (Pubmed Central) -  Mar 13, 2021   
    The current study aims to validate the CS as a reference region by (1) optimizing CS region of interest (ROI) to minimize spill-in from gray matter with high radioactivity concentrations; (2) investigating convergence of CS ROI values using ordered subset expectation maximization (OS-EM) reconstruction, and (3) comparing baseline CS volume of distribution (V) to nondisplaceable uptake in gray matter, V. Improving ROI definition and increasing OS-EM iterations during reconstruction decreased the difference between CS V and V. However, even with these corrections, CS V overestimated V by ∼35-40%. These measures showed significant correlation, suggesting that, though biased, the CS may be a useful estimate of nondisplaceable uptake, allowing for noninvasive quantification for SV2A PET.
  • ||||||||||  sodium valproate / Generic mfg., levetiracetam / Generic mfg.
    Journal, IO biomarker:  The effect of complicated febrile convulsion on hippocampal function and its antiepileptic treatment significance. (Pubmed Central) -  Mar 13, 2021   
    The incubation period of pups in the model group was significantly higher than that of the normal group, VPA group, and LEV group (P<0.05), and the number of crossing the station area was significantly less than that of the normal group, VPA group, and LEV group (P<0.05). Antiepileptic drugs are effective in preventing the recurrence of complicated febrile seizures (CFS), and the main mechanism may be related to the targeted regulation of BCL-2 on the apoptosis of the hippocampus in the nervous system.
  • ||||||||||  levetiracetam / Generic mfg., carbamazepine / Generic mfg.
    Clinical, Journal:  Efficacy of Levetiracetam in the Treatment of Sydenham Chorea. (Pubmed Central) -  Mar 10, 2021   
    Levetiracetam might be an option in the treatment of Sydenham chorea because of its acceptable effect and safety profile. This observation needs further support with evidence obtained through controlled and blinded trials.
  • ||||||||||  levetiracetam / Generic mfg.
    Enrollment open, Trial completion date, Trial primary completion date:  Levetiracetam Treatment of Neonatal Seizures (clinicaltrials.gov) -  Mar 9, 2021   
    P1/2,  N=100, Recruiting, 
    Early diagnosis and effective treatment play a vital role for favorable prognosis. Active, not recruiting --> Recruiting | Trial completion date: Dec 2020 --> Dec 2021 | Trial primary completion date: Dec 2019 --> Dec 2021
  • ||||||||||  Vimpat (lacosamide) / UCB, Daiichi Sankyo
    Clinical, Journal:  Nonconvulsive Status Epilepticus Associated with Theophylline: A Case Report (Pubmed Central) -  Mar 9, 2021   
    However, she developed severe tonic-clonic seizures with right sensory aphasia and right hemiplegia, for which an increased dose of lacosamide was added...We suspect that cerebral infarction may have aggravated the central nervous system damage caused by theophylline, thereby resulting in aminophylline-related non-convulsive status epilepticus. (Received 20 July 2020; Accepted 27 October 2020; Published 1 March 2021).
  • ||||||||||  Actemra IV (tocilizumab) / Roche, JW Pharma, Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
    Review, Journal:  Diagnosis and Treatment of Status Epilepticus. (Pubmed Central) -  Mar 5, 2021   
    Use of ketamine, megadose phenobarbital therapy, and multiple combinations of various AEDs including high doses of oral AEDs can also be considered...AEDs alone are poorly effective in the treatment of SE in autoimmune encephalitis. Immunotherapy such as steroids, immunoglobulin, rituximab, or tocilizumab can be effective.
  • ||||||||||  lorazepam / Generic mfg., midazolam hydrochloride / Generic mfg.
    Review, Journal:  Update on Anticonvulsant Therapy in the Emergent Small Animal Patient. (Pubmed Central) -  Mar 4, 2021   
    The benzodiazepine class of drugs (diazepam, midazolam, and lorazepam) often are the drug class of choice; however, levetiracetam and propofol also have been gaining favor as anticonvulsant drugs for acute seizure management. After cessation of seizures, practitioners then can discuss long-term seizure control on a case-by-case basis with clients.
  • ||||||||||  levetiracetam / Generic mfg.
    Review, Journal:  Modulation of Brain Hyperexcitability: Potential New Therapeutic Approaches in Alzheimer's Disease. (Pubmed Central) -  Mar 3, 2021   
    Clinical trials are ongoing to evaluate the potential efficacy in targeting hyperexcitability in AD, with levetiracetam showing some encouraging effects...Diagnostic challenges include identifying best biomarkers for measuring sub-clinical epileptiform discharges. Determining the timing of any intervention is critical and future trials will need to carefully stratify participants with respect to the phase of disease pathology.
  • ||||||||||  acyclovir / Generic mfg.
    [VIRTUAL] Prompt diagnosis and intervention for acyclovir associated acute kidney injury () -  Mar 2, 2021 - Abstract #NKFSCM2021NKF-SCM_701;    
    Creatinine reached a max of 2.72 mg/dL before trending down to 1.05 mg/dL. CONCLUSION The risk of acyclovir induced nephropathy can be minimized by utilizing IV fluid resuscitation to establish euvolemia before and after drug administration, avoiding rapid infusion and adjusting for reduced glomerular filtration rate.
  • ||||||||||  dexamethasone / Generic mfg., levetiracetam / Generic mfg.
    [VIRTUAL] Levetiracetam Associated High Anion Gap Metabolic Acidosis (HAGMA) in End Stage Renal Disease () -  Mar 2, 2021 - Abstract #NKFSCM2021NKF-SCM_641;    
    This constitutes the 4th reported critically ill patient with worsening HAGMA secondary to levetiracetam. The IV prescribed dose exceeded the recommended dose for creatinine clearance < 15 ml/min, which led to worsening HAGMA in this patient. CONCLUSION Awareness and careful dose adjustment is necessary for levetiracetam in patients with renal failure.