Diseases
Companies
Products
Productz
Mechanisms of Action
Sites
STK-002
/
Stoke Therap
Welcome,
Profile
Billing
Logout
Diseases
Trials
Trials
News
|
|||||||||
STK-002
/
Stoke Therap
Journal:
Antisense Oligonucleotide STK-002 Increases OPA1 in Retina and Improves Mitochondrial Function in Autosomal Dominant Optic Atrophy Cells.
(Pubmed Central) - Sep 12, 2024
STK-002 and enhanced OPA1 immunofluorescence were visualized in retinal ganglion cells of cynomolgus monkeys treated with the ASO. Cumulatively, these data support the progression of STK-002 toward the clinic as the first potential disease-modifying treatment for ADOA.