Sarcoma |
ChiCTR-PRC-08000244: A randomized, controlled, multi-center study evaluating combined operation modality vs imatinib alone (COMVIA) in patients with recurrent/metastatic c-kit positive gastrointestinal stromal tumor |
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| Completed | 4 | 210 | | imatinib + surgery ;imatinib | Cancer hospital affiliated to Fudan University; Beijing Novartis Pharma Co., Ltd., Beijing Novartis Pharma Co.,Ltd. Cancer hospital affiliated to Fudan University | gastrointestinal stromal tumor(GIST) | | | | |
2013-000052-17: Study to investigate the early prediction of toxicity following chemotherapy and differences in drug handling in Ewing's sarcoma patients |
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| Ongoing | 4 | 120 | Europe | Cyclophosphamide, Etoposide, Doxorubicin, Vincristine, Ifosfamide, Powder for solution for injection, Concentrate for solution for infusion, Solution for infusion, Solution for injection, Powder for concentrate for solution for infusion, Cyclophosphamide, Eposin, Doxorubicin Hydrochloride, Vincristine Sulphate, Ifosfamide | The Newcastle Upon Tyne Hospitals NHS Foundation Trust | Ewing sarcoma patients, Bone cancer, Diseases [C] - Cancer [C04] | | | | |
2014-001044-38: To study the effect of coca-cola on the exposure to imatinib in patients who underwent major gastrectomy. |
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| Ongoing | 4 | 11 | Europe | Glivec | Radboud University Nijmegen Medical Center, Radboud University Nijmegen Medical Center | Patients who are treated or will be treated with imatinib, who previously underwent major gastrectomy., Patients who are treated or will be treated with imatinib, who previously underwent major gastrectomy., Diseases [C] - Cancer [C04] | | | | |
2014-001561-27: Neuropathy caused by vincristine in children with leukemia: comparing one-hour infusions with short-term infusions Neuropathie door vincristine bij kinderen met leukemie: één-uurs infusen vergeleken met kortdurende infusies |
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| Ongoing | 4 | 88 | Europe | Vincristine sulfate, Vincristine Sulphate, VCR, Solution for infusion, Solution for injection | VU university medical center, The Netherlands Organisation for Health Research and Development (in Dutch: ZonMw) | Pediatric oncology, acute lymphoblastic leukemia, nephroblastoma, medulloblastoma, low-grade glioma, Hodgkin lymphoma, rhabdomyosarcoma Kinderoncologie, acute lymfatische leukemie, nefroblastoom, medulloblastoom, laaggradig glioom, Hodgkin lymfoom en rhabdomyosarcoom, Childhood cancer Kinderkanker, Diseases [C] - Cancer [C04] | | | | |
2006-005644-92: ENSAYO CLÍNICO ABIERTO, NO ALEATORIZADO, PILOTO, EN FASE II, DE LA COMBINACIÓN DE IFOSFAMIDA Y DOXORRUBICINA LIPOSÓMICA SEGUIDO DE RADIOTERAPIA COMO TRATAMIENTO ANTINEOPLÁSICO NEOADYUVANTE EN PACIENTES CON SARCOMA DE PARTES BLANDAS DE EXTREMIDADES DE ALTO GRADO (OPEN CLINICAL TEST, NOT RANDOMIZED, PILOT, IN PHASE II, OF IFOSFAMIDA AND DOXORRUBICINA LIPOSÓMICA COMBINATION FOLLOWED OF X-RAY LIKE NEOADJUVANT TREATMENT ANTINEOPLÁSICO IN PATIENTS WITH SARCOMA OF SOFT PARTS OF EXTREMITIES OF HIGH DEGREE) |
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| Ongoing | 4 | 36 | Europe | Doxorrubicina Liposomal (doxorrubicine liposomal), Ifosfamida, Doxorrubicina liposomal. En el protocolo, el tratamiento está definido por el principio activo (In protocol, treatment is defined only by active substance), Doxorrubicina liposomal. Ifosfamida En el protocolo, el tratamiento está definido por el principio activo (In protocol, treatment is defined only by active substance), Doxorrubicina liposomal. En el protocolo, el tratamiento está definido por el principio activo (In protocol, treatment is defined only by active substance), Doxorrubicina liposomal. Ifosfamida En el protocolo, el tratamiento está definido por el principio activo (In protocol, treatment is defined only by active substance) | Antonio Cubillo Gracián (Servicio de Oncología Médica - Hospital MD Anderson) | PACIENTES CON SARCOMA DE PARTES BLANDAS DE EXTREMIDADES DE ALTO GRADO(PATIENTS WITH OF SOFT PARTS SARCOMA OF HIGH DEGREE EXTREMITIES) | | | | |
2011-005554-62: A study investigating the pharmcokintetics (how the body processes with a drug) and pharmcodynamics (what effect the drug has on the body) of the chemotherapy drug doxorubicin, when used to treat children, adolescents and young adults with newly diagnosed cancers: osteosarcoma, Ewing\'s family of tumours, and Hodgkin lymphoma. |
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| Ongoing | 4 | 30 | Europe | doxorubicin, Doxorubicin, Doxorubicin, Doxorubicin | Australian Sarcoma Group (ASSG), ASSG (Australian Sarcoma Study Group) | Ewing family of tumoursOsteosarcomaHodgkin lymphoma | | | | |
2012-000425-45: Effect van ochtend- of avondinname van sunitinib op de medicijnspiegels in het bloed |
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| Ongoing | 4 | 18 | Europe | Sunitinib, Midazolam, EU/1/06/347/001-008, PL 29831/0140, Sutent, Dormicum, Sutent, Dormicum | | Renal Cell Cancer, GIST, pancreatic neuroendocrine tumor Niercelcarcinoom, GIST, p-NET | | | | |
ChiCTR-RNC-14004667: Study of plasma concentration of Imatinib in Chinese patients with gastrointestinal stromal tumor |
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| Completed | 4 | 300 | | Imatinib | The First Affiliated Hospital of Nanjing Medical University; The First Affiliated Hospital of Nanjing Medical University, The First Affiliated Hospital of Nanjing Medical University, Novartis China | Gastrointestinal stromal tumor | | | | |
2016-005252-21: Increasing the amount of pazopanib in the blood by splitting intake moments Verhogen van de hoeveelheid pazopanib in het bloed door het spreiden van inname momenten |
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| Ongoing | 4 | 10 | Europe | Tablet, Votrient | Netherlands Cancer Institute, Netherlands Cancer Institute | Patients for whom pazopanib is considered standard care (advanced renal cell carcinoma and advanced soft-tissue sarcoma). Patiënten voor wie behandeling met pazopanib standaard zorg is (gevorderd renaal cel carcinoom of gevorderd weke delen sarcoom)., Patients with advanced renal cell carcinoma or advanced soft-tissue sarcoma Patiënten met nierkanker of weke delen kanker, Diseases [C] - Cancer [C04] | | | | |
ChiCTR-OPN-15006162: Detection for effective plasma drug concentration in the field for patients with gastrointestinal stromal tumor with intolerance to 400mg Imatinib |
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| Not yet recruiting | 4 | 200 | | Imatinib 300mg/d ;Imtinib 400mg/d | West China Hospital, Sichuan University; Level of the institution:, none | Gastrointestinal stromal tumor | | | | |
ChiCTR-OPC-15006846: Study on preoperative plasma drug concentration for patients with giant gastrointestinal stromal tumors |
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| Not yet recruiting | 4 | 50 | | preoperative IM treatment | Department of gastrointestinal surgery, West China Hospital, Sichuan University; None, none | gastrointestinal stromal tumors | | | | |
ChiCTR-OPC-16007953: Clinical study of apatinib mesylate tablets in the treatment of refractory soft tissue sarcoma |
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| Not yet recruiting | 4 | 30 | | Medical and nursing education for patients with soft tissue sarcoma | Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, Henry csco- Cancer Research Fund | Refractory soft tissue sarcoma | | | | |
2017-002437-36: Study for an innovative approach for the monitoring of patients with gastrointestinal stromal tumour treated with imatinib Studio per la valutazione di un nuovo approccio per il monitoraggio di pazienti affetti da tumore stromale gastrointestinale e trattati con il farmaco imatinib |
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| Ongoing | 4 | 58 | Europe | imatinib, [035372059], Capsule, hard, GLIVEC - 100 MG 120 CAPSULE RIGIDE USO ORALE | CENTRO DI RIFERIMENTO ONCOLOGICO, Risorse dell'Istituto | Patients with gastrointestinal stromal tumour Pazienti affetti da tumore stromale gastrointestinale, Patients with gastrointestinal stromal tumour Pazienti affetti da tumore stromale gastrointestinale, Diseases [C] - Digestive System Diseases [C06] | | | | |
ChiCTR-OPC-17010758: Mesylate apatinib combined with chemotherapy in the treatment of clinical study of osteosarcoma recurrence and metastasis |
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| Recruiting | 4 | 40 | | Apatinib or apatinib + chemotherapy | Xijing Hospital affiliated to The Fourth Military Medical University; Xijing Hospital affiliated to The Fourth Military Medical University, 经费自筹 Self financing | osteosarcoma | | | | |
NCT03932071: Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma |
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| Recruiting | 4 | 150 | RoW | Zoledronic Acid | Second Affiliated Hospital, School of Medicine, Zhejiang University | Lung Metastases, Tumor Necrosis | 01/20 | 01/23 | | |
ChiCTR1900022667: A prospective randomized controlled trial for recombinant human thrombopoietin (rhTPO) at different intervening times to prevent and treat thrombocytopenia after chemotherapy with doxoburicin combined with isocyclophosphamide (AI) regimen in osteosarcoma and soft tissue sarcoma |
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| Not yet recruiting | 4 | 96 | | The patients distributed in group A was treated with rhTPO immediately at a dose of 300 U.d-1.kg-1, ih. ;The patients distributed in group B continued to observe and check blood every other day. When platelets were found to be less than 75*109/L, rhTPO was administered subcutaneously at a dose of 300 U.d-1.kg-1 once a day. | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Beijing Xisike Clinical Oncology Research Foundation | Osteosarcoma and soft tissue sarcoma | | | | |
ChiCTR1800017424: Mesylate tablets of apatinib as first-line treatment of metastatic soft tissue sarcoma, randomized, crossover, multi center clinical study |
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| Recruiting | 4 | 80 | | IFO+EPI regimen ;Pan apatinib scheme | General Hospital of Shenyang Military Area Command; General Hospital of Shenyang Military Area Command, Self-raising | metastatic soft tissue sarcoma | | | | |
ChiCTR1900022249: A prospective, single-arm, multi-center study for the efficacy and safety of Mecapegfilgrastim for the prevention of neutropenia 3 degrees and above in children with rhabdomyosarcoma or Ewing's sarcoma after chemotherapy |
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| Not yet recruiting | 4 | 30 | | Subcutaneous injection of Mecapegfilgrastim according to the patient's body weight 24-36 hours after chemotherapy | Capital Medical University, Beijing Children's Hospital; Capital Medical University, Beijing Children's Hospital, Researcher self-raising | Neutrophil reduction after chemotherapy | | | | |
2020-005751-21: Clinical Trial Extension Study with Avapritinib for Patients with Gastrointestinal Stromal Tumors |
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| Not yet recruiting | 4 | 5 | Europe | Avapritinib, BLU-285, Tablet | Blueprint Medicines, Blueprint Medicines | Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST), Gastrointestinal Tumours, Diseases [C] - Cancer [C04] | | | | |
ChiCTR1800016574: Comparative study of the efficacy of adriamycin and liposome doxorubicin in the treatment of osteosarcoma |
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| Recruiting | 4 | 150 | | Chemotherapy | Beijing Jishuitan Hospital; Beijing Jishuitan Hospital, None | Osteosarcoma | | | | |
ChiCTR-IPR-16008568: A clinical trial for zoledronic acid added into new adjuvant chemotherapy on osteosarcoma patients |
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| Recruiting | 4 | 150 | | zoledronate ;placebo | 2nd affiliated hospital of ZheJiang University; 2nd Affiliated Hospital, ZheJiang University, raise independently | osteosarcoma | | | | |
ChiCTR1800016838: Clinical trial of secondary prevention of recombinant human thrombopoietin in the prevention of thrombocytopenia in advanced osteosarcoma with apatinib and docetaxel |
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| Recruiting | 4 | 60 | | rhTPO | Affiliated Sixth People's Hospital, Shanghai Jiaotong University; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, funding | thrombocytopenia in advanced osteosarcoma | | | | |
ChiCTR1800016856: A prospective, randomized, controlled clinical trial of thalidomide against small molecule VEGFR oral targeted drug grade III-IV adverse reactions |
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| Recruiting | 4 | 440 | | Apatinib + thalidomide 50~150mg/d, po.QN ;Apatinib ;Anlotinib Hydrochloride + thalidomide 50~150mg/d, po.QN ;Anlotinib ;Apatinib + thalidomide 50~150mg/d, po.QN ;Apatinib ;Anlotinib Hydrochloride + thalidomide 50~150mg/d, po.QN ;Anlotinib | Affiliated Sixth People's Hospital, Shanghai Jiaotong University; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Self-raised | Patients with advanced gastric cancer, lung cancer, and osteosarcoma taking apatinib or antatinib | | | | |
ChiCTR1800015245: Five Versus Three Years of Adjuvant Imatinib in Patients at Significant Risk for Recurrence Following Complete Resection of Primary Gastrointestinal Stromal Tumor: A Phase III, Randomized, Multicenter Study (FAITH study) |
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| Recruiting | 4 | 380 | | Prolonging the adjuvant duration of imatinib mesylate for 2 years ;not prolong the adjuvant duration and follow up | Sun Yat Sen University, Cancer Center; Sun Yat Sen University, Cancer Center, self-financing | Gastrointestinal Stromal Tumor | | | | |
NCT04854018: Indo-cyanine Green (ICG) in Paediatric Oncology MIS |
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| Completed | 4 | 20 | Europe | Indocyanine green, Verdye, Diagnostic Green | Birmingham Women's and Children's NHS Foundation Trust | Pediatric Renal Tumor, Metastatic Osteosarcoma, Metastatic Ewing Sarcoma, Pulmonary Metastasis, Rhabdomyosarcoma, Non-Rhabdo. Soft Tissue Sarcoma | 09/22 | 09/22 | | |
ChiCTR1800019995: A Clinical Study for the Efficacy and Safety of Apatinib Combined with Gemcitabine plus Paclitaxel in Patients with Advanced Hepatosarcomatoid Carcinoma |
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| Not yet recruiting | 4 | 40 | | Apatinib 250mg, po, qd+Gemcitabine, iv, d1, d8+Paclitaxel, iv, d1 | First Affiliated Hospital of Zhengzhou University; First Affiliated Hospital of Zhengzhou University, Self-pay | Advanced Hepatosarcomatoid Carcinoma | | | | |
NCT04347122: Tranexamic Acid in Radical Resection and Endoprosthetic Reconstruction |
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| Completed | 4 | 16 | US | Tranexamic Acid (TXA) | University of Kansas Medical Center | Musculoskeletal Cancer, Sarcoma,Soft Tissue | 08/23 | 08/23 | | |
ChiCTR2100044810: A controlled clinical study the combination of first-line immunotherapy and targeted therapy for advanced sarcomatoid renal cell carcinoma |
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| Recruiting | 4 | 40 | | camrelizumab plus Pazopanib Tablets ;Pazopanib Tablets | Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, Partially self-financing | Advanced sarcomatoid renal cell carcinoma | | | | |
| Recruiting | 4 | 1200 | | Nil | Jiangsu Cancer Hospital; Jiangsu Cancer Hospital, CTTQ Pharmaceutical Group Co., Ltd. | Non-small cell lung cancer, soft tissue sarcoma, thyroid like cancer or other | | | | |
| Completed | 4 | 57 | Europe, Canada, US, RoW | Nilotinib, AMN107 | Novartis Pharmaceuticals | Chronic Myelogenous Leukemia (CML), Metastatic Gastrointestinal Stromal Tumors (GIST), Acute Lymphoblastic Leukemia (ALL), Receptor Tyrosine Kinase (KIT) Mutated Melanoma | 07/23 | 07/23 | | |
ChiCTR2100049974: An exploratory clinical study of Camrelizumab combined with AD chemotherapy in the first-line treatment of metastatic or inoperable undifferentiated pleomorphic sarcoma (UPS) |
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| Not yet recruiting | 4 | 30 | | Drug intervention | Peking University Cancer Hospital; Peking University Cancer Hospital, NA | undifferentiated pleomorphic sarcoma | | | | |
ChiCTR2100052208: An observational clinical study of ripatinib in the treatment of patients with complex genetically mutated gastrointestinal stromal tumors |
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| Not yet recruiting | 4 | 30 | | Ripatinib | The First Affiliated Hospital of Nanjing Medical University; The First Affiliated Hospital of Nanjing Medical University, Zai Lab Pharmaceutical Trading (Suzhou) Co., Ltd. | gastrointestinal stromal tumor | | | | |
Li2CO3, NCT01669369: Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma |
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| Recruiting | 4 | 400 | RoW | Lithium Carbonate, Lithobid, Placebo, PLACEBO TREATMENT | Sun Yat-sen University, Qilu Hospital of Shandong University, Nanfang Hospital of Southern Medical University, Shenzhen Second People's Hospital, Guangdong Provincial Hospital of Traditional Chinese Medicine, Shanghai 6th People's Hospital | Osteosarcoma | 12/23 | 12/23 | | |
NCT03244020: LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology |
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| Enrolling by invitation | 4 | 1434 | US | Aspirin 325mg, ASA, Enoxaparin 40Mg/0.4mL Prefilled Syringe, Lovenox | Massachusetts General Hospital | Sarcoma, Soft Tissue Sarcoma, Bone Sarcoma, Bone Metastases, Venous Thromboembolism, Hematoma, Anticoagulant-induced Bleeding | 12/27 | 07/28 | | |
SDCMK, NCT06236022: The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus |
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| Recruiting | 4 | 276 | RoW | Sirolimus | Tongji Hospital, Wuhan Central Hospital, Wuhan Fourth Hospital, Wuhan University | Dilated Cardiomyopathy, Kaposi's Sarcoma-Associated Herpesvirus Infection | 12/28 | 12/28 | | |
ChiCTR2200060233: A prospective, parallel controlled study of DEB-TACE versus arterial infusion chemotherapy in the treatment of metastatic or recurrent soft tissue sarcoma |
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| Not yet recruiting | 4 | 70 | | Drug elution embolism-Transcatheter arterial chemoembolization, DEB-TACE group ;Arterial infusion chemotherapy | The Fifth Medical Center of PLA General Hospital; The Fifth Medical Center of PLA General Hospital, Beijing Medical Award Foundation | Soft tissue sarcoma | | | | |
ChiCTR2100052825: Phase II clinical studies of single center, open, single arm of paclitaxel (albumin binding) in combination with camrelizumab second line and above line treatment of metastatic/locally unresectable soft tissue sarcoma |
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| Not yet recruiting | 4 | 40 | | Camrelizumab and chemotherapy | He'nan Tumor Hospital; He'nan Tumor Hospital, Self-funded | Soft tissue sarcoma | | | | |
ChiCTR2300075388: Clinical study of trilaciclib for the prevention of severe myelosuppression after chemotherapy in patients with bone and soft tissue sarcoma |
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| Recruiting | 4 | 550 | | Patients with bone and soft tissue sarcoma who had IV-degree bone marrow suppression in previous chemotherapy did not receive Turacilli for preventive treatment. ;Patients with bone and soft tissue sarcoma who have experienced IV-degree bone marrow inhibition in chemotherapy should receive trarasili (240 mg/m2, intravenous administration within 4 hours before chemotherapy, and the number of days of medication is determined according to the number of days of chemotherapy) before the next chemotherapy. ;Patients with bone and soft tissue sarcoma will not receive prophylactic treatment until they plan to receive a high-risk chemotherapy regimen. ;Before patients with bone and soft tissue sarcoma are proposed to receive high-FN-risk chemotherapy, trarasili (240 mg/m2, intravenous administration within 4 hours before chemotherapy, and the number of days of medication is determined according to the number of days of chemotherapy) for preventive treatment. | Affiliated Sixth People's Hospital, Shanghai Jiaotong University; Affiliated Sixth People's Hospital, Shanghai Jiaotong University, Self-finance | Bone and soft tissue sarcoma | | | | |
ChiCTR1800017181: A prospective, single-arm, multi-center clinical study of adjuvant treatment of Gastrointestinal Stromal Tumors with Imatinib Mesylate (Gnical) |
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| Not yet recruiting | 4 | 150 | | adjuvant Gastrointestinal Stromal Tumors after Imatinib Mesylate | Henan Provincial People's Hospital; Henan Provincial People's Hospital, enterprise | Gastrointestinal Stromal Tumors | | | | |
ChiCTR2000033298: A single-arm multicenter trial of the combination of anlotinib with chemotherapy in patients with Stage IIB classic osteosarcoma of the extremity |
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| Recruiting | 4 | 52 | | Anlotinib combined with Doxorubicin and cisplatin | West China Hospital of Sichuan University; West China Hospital of Sichuan University, CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD | Classic osteosarcoma | | | | |
ChiCTR1900023489: The Protection Role of Metformin in Female Reproductive System Development and Fertility Preservation for children with malignant tumors with Chemotherapy: A Double-Blind, Randomized, Placebo-Controlled Study |
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| Not yet recruiting | 4 | 138 | | Placebo ;Metformin | Tongji Medical College, Huazhong University of Science and Technology; Tongji Medical College, Huazhong University of Science and Technology, Foundation of research pioneering project of Tongji hospital | Childhood malignancy (leukemia, lymphoma, rhabdomyosarcoma, etc.) | | | | |
NCT04033081: Registry of Sarcoma Patients Treated With Permanently Implantable LDR CivaSheet® |
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| Recruiting | 4 | 100 | US | CivaSheet, brachytherapy, Intraoperative Radiation Therapy | CivaTech Oncology, TAB Clinical | Sarcoma | 12/24 | 12/28 | | |
| Active, not recruiting | 4 | 34 | Europe | Nilotinib | Novartis Pharmaceuticals | Gastrointestinal Stromal Tumors | 12/24 | 12/24 | | |
NCT03144206: Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study |
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| Recruiting | 4 | 20 | US | Hyperbaric oxygen | Duke University | Sarcoma, Hyperbaric Oxygen Therapy | 12/26 | 12/26 | | |
ChiCTR2000033695: A prospective, one-arm, clinical study for letrozole in the treatment of uterine sarcoma |
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| Not yet recruiting | 4 | 20 | | letrozole | International Peace Maternal and Child Health Center affiliated to Shanghai Jiaotong University; International Peace Maternal and Child Health Center affiliated to Shanghai Jiaotong University, International Natural Science Foundation | uterine sarcoma | | | | |
NCT04825574: Study for Patients Previously Treated in Avapritinib Clinical Trials |
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| Active, not recruiting | 4 | 5 | Europe | Avapritinib, BLU-285 | Blueprint Medicines Corporation | Gastrointestinal Stromal Tumors | 08/25 | 08/25 | | |
NATARS, NCT05844813: Neoadjuvant Chemotherapy Combined With Targeted Treatment in High-risk Retroperitoneal Sarcoma |
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| Enrolling by invitation | 4 | 102 | RoW | Doxorubicin+Ifosfamide+Anlotinib(AI+A), Radical Surgery | Peking University International Hospital, Shanghai Zhongshan Hospital, The Affiliated Hospital of Qingdao University, Peking University First Hospital, Shanghai Cancer Hospital, China, First Affiliated Hospital Xi'an Jiaotong University, Beijing Friendship Hospital | Retroperitoneal Sarcoma | 11/25 | 11/27 | | |
NCT01742299 / 2012-002540-25: Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator |
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| Active, not recruiting | 4 | 155 | Europe, US, RoW | imatinib mesylate, STI571 | Novartis Pharmaceuticals | GIST and CML | 04/33 | 04/33 | | |