| Recruiting | 1a/1b | 198 | Europe, US | NG-350A plus Pembrolizumab | Akamis Bio, Merck Sharp & Dohme LLC | Epithelial Tumor, Metastatic Cancer | 03/25 | 05/25 | | |
REVOLUTION, NCT04787991: Exploratory Platform Trial to Evaluate Immunotherapy Combinations With Chemotherapy for the Treatment of Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma |
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| Active, not recruiting | 1 | 45 | US | Nivolumab (Cohort A), Opdivo, Ipilimumab (Cohort A, B and C), Yervoy, Hydroxychloroquine (HCQ) (Cohort B), Plaquenil, Nab-paclitaxel (nP) (Cohort A, B and C), Abraxane, Gemcitabine (gem) (Cohort A, B and C), Gemzar, NG350A (Cohort C) | Cancer Insight, LLC, Bristol-Myers Squibb, Cancer Research Institute, New York City, Akamis Bio | Metastatic Pancreatic Adenocarcinoma | 10/24 | 01/25 | | |
| Not yet recruiting | 1 | 30 | NA | NG-350A IV administration, Capecitabine oral administration, Radiotherapy | Akamis Bio | Locally Advanced Rectal Cancer (LARC) | 02/26 | 01/29 | | |