mexiletine / Generic mfg.  >>  Phase 3
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8 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
mexiletine / Generic mfg.
NCT00000518: Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)

Completed
3
US
electrophysiology, electrocardiography, ambulatory, imipramine, mexiletine, procainamide, quinidine, sotalol
University of Utah, National Heart, Lung, and Blood Institute (NHLBI)
Arrhythmia, Cardiovascular Diseases, Death, Sudden, Cardiac, Heart Diseases, Tachycardia, Ventricular, Ventricular Arrhythmia, Ventricular Fibrillation
 
12/92
CASCADE, NCT00000464: Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation

Completed
3
US
amiodarone, imipramine, mexiletine, procainamide, propafenone, quinidine, sotalol
University of Washington, National Heart, Lung, and Blood Institute (NHLBI)
Arrhythmia, Cardiovascular Diseases, Heart Arrest, Heart Diseases, Myocardial Infarction, Ventricular Fibrillation
12/92
 
NCT00004647: Phase III Randomized, Double-Blind, Placebo-Controlled Study of Mexiletine for Painful Diabetic Neuropathy

Completed
3
40
US
mexiletine
National Center for Research Resources (NCRR), University of Tennessee
Pain, Diabetic Neuropathies, Paresthesia
 
02/99
MYOMEX, NCT02336477 / 2010-020923-37: Mexiletine and Non Dystrophic Myotonias

Completed
3
24
Europe
Mexiletine, placebo
Assistance Publique - Hôpitaux de Paris
Non-dystrophic Myotonias, Paramyotonia Congenita, Myotonia Congenita
01/14
01/14
2021-003784-94: Which treatment are the best to reduce myotonia?

Ongoing
3
32
Europe
Capsule, hard, Capsule, Namuscla, Lamotrigin ”Nordic Prime" 25 mg, Lamotrigin ”Nordic Prime" 50 mg, Lamotrigin ”Nordic Prime" 100 mg
Rigshospitalet, department of Neurology, Region Hovedstadens Forskningsfond til Sundhedsforskning
Myotonia Congenita (Becker and Thomsen type), Paramyotonia Congenita, and Hyperkalemic periodic paralysis, Non-dystofic myotonia, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]
 
 
MEND, NCT05017155: MExiletine Versus Lamotrigine in Non-Dystrophic Myotonias

Recruiting
3
60
Europe
Mexiletine, Lamotrigine 25Mg Oral Tablet, Extended Release
University College, London
Non-Dystrophic Myotonia
08/23
04/24
NCT04624750 / 2019-003757-28: Open Label Study in Adolescents and Children With Myotonic Disorders

Recruiting
3
14
Europe
Mexiletine, Namuscla ™
Lupin Ltd.
Myotonic Dystrophy
06/24
08/24
MIND, NCT04700046: Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2

Withdrawn
3
158
NA
Mexiletine 167 mg, Placebo
Lupin Ltd.
Myotonic Dystrophy Type 1 and Type 2
07/24
08/24

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