| Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi |
ACTRN12611001224910: REmoval Of Tacrolimus For Sirolimus Following Thymoglobulin Induction On The Development of REgulatory T Cells in Kidney Transplant Patients |
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| Not yet recruiting | 4 | 30 | | | Department of Health, Genzyme Australia, Pfizer Australia | Development of circulating regulatory T cells, Kidney transplant function, complications and biopsy, Cardiovascular health, Metabolic outcomes (glucose abnormality), Clinical significant infections and cancers | | | | |
ACTRN12610000697088: Ciclosporine Azathioprine versus Tacrolimus mycophenolate mofetil in renal transplantation |
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| Active, not recruiting | 4 | 300 | | | Assistance publique des Hopitaux de Marseille, Assistance publique des Hopitaux de Marseille | renal transplantation, Immunosuppressive treatment in renal transplantation, Acute rejection and transplant survival in renal transplantation | | | | |
2006-004830-34: TACROLIMUS AND PRETRANSPLANT HIGH-DOSE R-ATG INDUCTION VS TACROLIMUS MONOTHERAPY AS TOLEROGENIC IMMUNOSUPPRESSION IN ADULT LIVER TRANSPLANTATION.AN OPEN LABEL, RANDOMISED, PROSPECTIVE AND CONTROLLED TRIAL. |
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| Ongoing | 4 | 100 | Europe | R-ATG, TACATG, Intravenous infusion, R- ATG | UNIVERSITY HOSPITALS ST LUC | Studying the possibility of tolerance induction in adult liver transplantation adding one single dose of polyclonal antilymphocytic antibodies to an calcineurin -inhibitor based immunosuppression using tacrolimus. | | | | |
2005-000855-14: Multicenter, not controlled, prospectic clinical phase IV study: safety and efficacy of an immunosuppressive regimen with Thymoglobuline and Rapamune in patients receiving a renal transplantation from a marginal donor. |
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| Ongoing | 4 | 65 | Europe | NA, NA, RAPAMUNE*1MG 100 CPR, RAPAMUNE*2MG 30 CPR, RAPAMUNE*OS 60 ML 1 MG, THYMOGLOBULINE*IV 1F 25MG +F, RAPAMUNE*1MG 100 CPR, RAPAMUNE*2MG 30 CPR, RAPAMUNE*OS 60 ML 1 MG, THYMOGLOBULINE*IV 1F 25MG +F | AZIENDA OSPEDALIERA DI PADOVA | Acute rejection prophylaxis after single-double kidney transplantation from marginal donors making use of a not nephrotoxic immunosuppressive regimen. | | | | |
ChiCTR1800017266: A single center prospective study comparing the effects of induction therapy in Chinese donation after cardiac death (DCD) patients between rabbit anti-human thymocyte immunoglobulin (Thymoglobulin) and basiliximab ( Simulect) |
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| Recruiting | 4 | 80 | | rATG standard dose (5.0-6.0 mg/kg) ;rATG standard dose (4.0-5.0 mg/kg) ;Basiliximab standard dose | General Hospital of Chinese People's Armed Police Forces; General Hospital of Chinese People's Armed Police Forces, Hospital | Kidney Transplantation | | | | |
ChiCTR-OIN-17011174: A Study of Thymoglobuline? Induction Therapy in Adult Recipients of Donated After Cardiac Death Kidney Transplant |
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| Recruiting | 4 | | | | The First Affiliated Hospital of Xi'an JiaoTong University; Sanofi (Beijing) Pharmaceutical Co., Ltd., Sanofi (Beijing) Pharmaceutical Co., Ltd. | Diseases of the kidney and urinary system | | | | |
NCT02745717: The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Severe Aplastic Anemia |
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| Completed | 4 | 60 | RoW | Thymoglobulin, Thymoglobuline, Cord blood, Cyclosporine Oral Product, cyclosporine A | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Ruijin Hospital, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Tongji Hospital, Tongji University School of Medicine, Zhejiang Provincial Hospital of TCM | Severe Aplastic Anemia | 12/21 | 12/21 | | |
NCT02938741: ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors |
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| Recruiting | 4 | 130 | RoW | Anti-human Thymoglobulin, (r-ATG ）, Placebo | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | Lymphoblastic Lymphoma | 12/21 | 12/22 | | |
NCT04009525: Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study |
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| Recruiting | 4 | 800 | RoW | Busulfan, Bu, Cyclophosphamide, Cy, Fludarabine, Flu, Thymoglobulin, ATG, cyclosporine A, CsA, Mycophenolate mofetil, MMF, Tacrolimus, FK506, Methotrexate, MTX, Basiliximab, Simulect, Ruxolitinib | First Affiliated Hospital of Guangxi Medical University, Peking University People's Hospital, Ruijin Hospital, The 923th Hospital of People's Liberation Army, Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou General Hospital, Hainan General Hospital, The Affiliated Hospital Of Guizhou Medical University, The First People's Hospital of Yunnan | Thalassemia Major | 05/22 | 05/23 | | |
| Recruiting | 4 | 80 | US | Twice-daily Tacrolimus, Once-daily envarsus XR, Induction Immunosuppression with Basiliximab or Rabbit Anti Thymoglobulin (rATG), Methylprednisolone, prednisone, Steroids, Mycophenolate mofetil (MMF) or Mycophenolic acid (MPA), Twice a day anti-metabolite, Azathioprine, Once a day anti-metabolite | University of Southern California, Veloxis Pharmaceuticals | Kidney Transplantation, Kidney Transplant Rejection | 02/25 | 02/25 | | |
BETTER, NCT04849533: Belatacept With Early Steroid Withdrawal rATG and Everolimus in Renal Transplantation ( Trial) |
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| Recruiting | 4 | 120 | US | Belatacept, Nulojix, Everolimus, Zortress, mycophenolate mofetil, Cellcept, corticosteroids, Prednisone, rabbit antithymocyte globulin, rATG, thymoglobulin | University of Cincinnati | Kidney Transplant Rejection | 07/23 | 07/24 | | |
NCT05634915: Clinical Study of rATG Individualized Administration in Haploidentical Hematopoietic Stem Cell Transplantation |
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| Recruiting | 4 | 90 | RoW | Individual ATG, ATG | The First Affiliated Hospital of Soochow University | Hematopoietic Stem Cell Transplantation, Acute Leukemia | 12/24 | 05/25 | | |
PHASAL-GA, NCT05743400: Thymoglobulin® Pharmacokinetics in Patients Undergoing Hematopoietic Stem Cell Transplantation |
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| Recruiting | 4 | 35 | Europe | Thymoglobulin 25 milligrams (mg) Injection, blood test | Hospices Civils de Lyon | Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy | 04/25 | 04/25 | | |
2011-002052-14: EURO-HIT-HLH European cooperative pilot study for testing Hybrid ImmunoTherapy for Hemophagocytic LymphoHistiocytosis Studio cooperativo pilota per la valutazione della terapia immunologica combinata della Linfoistiocitosi Emofagocitica Familiare |
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| Ongoing | 3/4 | 24 | Europe | THYMOGLOBULINE*1F 25MG 10ML, DESAMETASONE FOSF*IM EV 3F 4MG, ETOPOSIDE TEVA*FL 10ML 20MG/ML, METHOTREXATE*INIET 1FL 500MG20, THYMOGLOBULINE*1F 25MG 10ML, DESAMETASONE FOSF*IM EV 3F 4MG, ETOPOSIDE TEVA*FL 10ML 20MG/ML, METHOTREXATE*INIET 1FL 500MG20 | AZIENDA OSPEDALIERA MEYER, AOU Meyer, AOUMeyer, Florence, HistiozytoseHilfe e.V., Universitätsklinikum Hamburg Eppendorf, St. Anna Kinderkrebsforschung e.V. | Familial hemophagoytic lymphohistiocytosis Linfoistiocitosi emofagocitica familiare. | | | | |
