Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi  >>  Phase 1
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12 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
FluBuATG, NCT02916979: Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using

Completed
1
20
US
Fludarabine, Busulfan, Rabbit ATG, Methotrexate
Dartmouth-Hitchcock Medical Center
Leukemia, Lymphoid, Leukemia, Myeloid, Myelodysplastic Syndromes, Myelofibrosis, Lymphoma, Malignant, Multiple Myeloma, Waldenstrom Macroglobulinemia
06/19
02/22
NCT02867800: Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

Completed
1
24
US
Diphenhydramine, Benadryl, Acetaminophen, Tylenol, Methylprednisolone, Medrol, Meperidine, Demerol, Alemtuzumab, Lemtrada, Thymoglobulin, Genzyme, Fludarabine, Fludara, Melphalan, Alkeran, Thiotepa, Thioplex, Cyclosporine, Neoral, Tacrolimus, Protopic, Methotrexate, Trexall, Abatacept, CTLA4-Ig, Orencia, Marrow infusion, stem cell transplant, Sirolimus, Rapamune, Mycophenolate Mofetil, MMF
Monica Bhatia
Sickle Cell Disease, Graft Versus Host Disease
12/21
12/23
NCT02122081: Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

Completed
1
33
US
radiation therapy, irradiation, radiotherapy, therapy, radiation, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, tacrolimus, FK 506, Prograf, methotrexate, amethopterin, Folex, methylaminopterin, Mexate, MTX, allogeneic bone marrow transplantation, bone marrow therapy, allogeneic, bone marrow therapy, allogenic, transplantation, allogeneic bone marrow, transplantation, allogenic bone marrow, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, PBPC transplantation, PBSC transplantation, peripheral blood progenitor cell transplantation, transplantation, peripheral blood stem cell, laboratory biomarker analysis
Sumithira Vasu
Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia
09/22
09/22
NCT04776850: Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Withdrawn
1
40
NA
Bortezomib, [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid, LDP 341, MLN341, PS-341, PS341, Velcade, Busulfan, 1, 4-Bis[methanesulfonoxy]butane, BUS, Bussulfam, Busulfanum, Busulfex, Busulphan, CB 2041, CB-2041, Glyzophrol, GT 41, GT-41, Joacamine, Methanesulfonic Acid Tetramethylene Ester, Methanesulfonic acid, tetramethylene ester, Mielucin, Misulban, Misulfan, Mitosan, Myeleukon, Myeloleukon, Myelosan, Mylecytan, Myleran, Sulfabutin, Tetramethylene Bis(methanesulfonate), Tetramethylene bis[methanesulfonate], WR-19508, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamide Monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR- 138719, Dexamethasone, Aacidexam, Adexone, Aknichthol Dexa, Alba-Dex, Alin, Alin Depot, Alin Oftalmico, Amplidermis, Anemul mono, Auricularum, Auxiloson, Baycadron, Baycuten, Baycuten N, Cortidexason, Cortisumman, Decacort, Decadrol, Decadron, Decadron DP, Decalix, Decameth, Decasone R.p., Dectancyl, Dekacort, Deltafluorene, Deronil, Desamethasone, Desameton, Dexa-Mamallet, Dexa-Rhinosan, Dexa-Scheroson, Dexa-sine, Dexacortal, Dexacortin, Dexafarma, Dexafluorene, Dexalocal, Dexamecortin, Dexameth, Dexamethasone Intensol, Dexamethasonum, Dexamonozon, Dexapos, Dexinoral, Dexone, Dinormon, Dxevo, Fluorodelta, Fortecortin, Gammacorten, Hexadecadrol, Hexadrol, Lokalison-F, Loverine, Methylfluorprednisolone, Millicorten, Mymethasone, Orgadrone, Spersadex, TaperDex, Visumetazone, ZoDex, Fludarabine Phosphate, 2-F-ara-AMP, 9H-Purin-6-amine, 2-fluoro-9-(5-O-phosphono-.beta.-D-arabinofuranosyl)-, Beneflur, Fludara, SH T 586, Hematopoietic Cell Transplantation, HCT, Hematopoietic Stem Cell Transplantation, HSCT, Stem Cell Transplant, stem cell transplantation, Lapine T-Lymphocyte Immune Globulin, Anti-Thymocyte Globulin Rabbit, Grafalon, Rabbit Anti-Human Thymocyte Globulin (RATG), Rabbit Anti-Thymocyte Globulin, Rabbit Antithymocyte Globulin, Rabbit ATG, rATG, Thymoglobulin, Mycophenolate Mofetil, CellCept, MMF, Plasmapheresis, Plasma Exchange, Therapeutic Plasma Exchange, Therapeutic Plasmapheresis, Rituximab, ABP 798, BI 695500, C2B8 Monoclonal Antibody, Chimeric Anti-CD20 Antibody, CT-P10, IDEC-102, IDEC-C2B8, IDEC-C2B8 Monoclonal Antibody, MabThera, Monoclonal Antibody IDEC-C2B8, PF-05280586, Rituxan, Rituximab ABBS, Rituximab Biosimilar ABP 798, Rituximab Biosimilar BI 695500, Rituximab Biosimilar CT-P10, Rituximab Biosimilar GB241, Rituximab Biosimilar IBI301, Rituximab Biosimilar JHL1101, Rituximab Biosimilar PF-05280586, Rituximab Biosimilar RTXM83, Rituximab Biosimilar SAIT101, Rituximab Biosimilar SIBP-02, rituximab biosimilar TQB2303, rituximab-abbs, RTXM83, Truxima, Tacrolimus, FK 506, Fujimycin, Hecoria, Prograf, Protopic
M.D. Anderson Cancer Center
Beta Thalassemia Major, Sickle Beta 0 Thalassemia, Sickle Beta Plus Thalassemia, Sickle Beta Thalassemia, Sickle Cell Disease, Sickle Cell-SS Disease
12/22
12/22
NCT02512497: Romidepsin Maintenance After Allogeneic Stem Cell Transplantation

Recruiting
1
10
US
Romidepsin, Istodax, Depsipeptide, FK228, Busulfan, Busulfex, Myleran, Fludarabine, Fludarabine Phosphate, Fludara, Stem Cell Transplant, Thymoglobulin, ATG, Rabbit Antithymocyte Globulin, Rabbit Antilymphocyte Globulin, Rabbit ATG, rATG
Ohio State University Comprehensive Cancer Center, Celgene Corporation
Cutaneous T-cell Lymphoma, T-Prolymphocytic Leukemia, T-Large Granulocytic Leukemia, T-Lymphoblastic Leukemia/Lymphoma, Peripheral T-Cell Lymphoma
12/22
12/22
NCT03531736: T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

Active, not recruiting
1
17
US
Antithymocyte globulin (Rabbit), ATG, fludarabine, total body irradiation, TBI, cyclophosphamide, Rituxan, Allogeneic Hematopoietic Stem Cell Transplantation
Memorial Sloan Kettering Cancer Center
Myeloid Diseases
05/25
05/25
NCT02928991: Fludarabine Based RIC for Bone Marrow Failure Syndromes

Recruiting
1
25
US
MRD-BMT with Fludarabine-based RIC for Acquired AA, MRD-BMT with Fludarabine-based RIC for iBMF with trilineage aplasia, MRD-BMT with Fludarabine-based RIC for iBMF without trilineage aplasia
Children's Hospital of Philadelphia
Bone Marrow Failure Syndromes
02/25
12/26
NCT03249831: A Blood Stem Cell Transplant for Sickle Cell Disease

Active, not recruiting
1
3
US
Cyclophosphamide, Cytoxan, Pentostatin, NIPENT, Rabbit anti-thymocyte globulin, Rabbit ATG, Thymoglobulin, Tacrolimus, PROGRAF®, Mycophenolate mofetil, MMF, CellCept®, Myfortic, CD4+ T-cell-depleted Haploidentical Hematopoietic Transplant, CD4+ T-cell depleted HaploHCT, CD4+ T-cell depleted hematopoietic progenitor cell (HPC) product
City of Hope Medical Center, California Institute for Regenerative Medicine (CIRM)
Sickle Cell Disease, Sickle Cell Disorder, Hemoglobinopathies, Thalassemia, Anemia, Sickle Cell
11/24
11/24
NCT04540380: Renal Allograft Tolerance Through Mixed Chimerism - SMC/MGH

Recruiting
1
20
US
Rituximab, Fludarabine, Cyclophosphamide, Thymic irradiation and Siplizumab, Combined bone marrow and kidney transplant
Massachusetts General Hospital
Renal Failure
01/25
06/25
NCT05806749: Immunological Tolerance in Patients With Mismatched Kidney Transplants

Active, not recruiting
1
16
US
Donor CD34+, CD3+. and belumosudil
University of California, Los Angeles
End Stage Kidney Disease, Immunological Tolerance, Kidney Transplant Failure and Rejection, Chronic Kidney Diseases
08/25
08/26
NCT04098393: Giving Chemotherapy for a Shortened Amount of Time Before a Stem Cell Transplantation

Active, not recruiting
1
39
US
Busulfan 3.2 mg/kg/day, Fludarabine, Melphalan, Antithymocyte globulin (ATG), Busulfan 0.8 mg/kg, Allogeneic hematopoietic cell transplantation (Allo-HCT)
Memorial Sloan Kettering Cancer Center
Hematologic Malignancies
09/25
09/25
NCT05298358: RIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis

Recruiting
1
30
US
RIC alloBMT w PTCy in refractory SSc
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Systemic Sclerosis
08/27
11/27

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