Leukemia  >>  Thymoglobulin (anti-thymocyte globulin (rabbit))  >>  Phase 3
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
2021-003282-36: Studying Conditioning Regimen In Pediatric Transplantation – AML

Ongoing
3
230
Europe
Cyclophosphamide, Melphalan, Fludarabine, Clofarabine, Concentrate for dispersion for infusion, Powder for solution for infusion, Powder for dispersion for infusion, Busilvex, Grafalon, Thymoglobuline
Västra Götalands Regionen, Funding application submitted.
Acute myeloid leukemia (AML) in children, AML is a type of blood cancer, Diseases [C] - Blood and lymphatic diseases [C15]
 
 
NCT01295710: Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)

Checkmark For moderate to severe chronic graft-versus-host-disease
Oct 2017 - Oct 2017: For moderate to severe chronic graft-versus-host-disease
Completed
3
260
US, RoW
US-ATG-F, Anti-human-T-lymphocyte Immune Globulin, Rabbit, Placebo
Neovii Biotech
GVHD, Adult Acute Myeloid Leukemia, Adult Acute Lymphoid Leukemia, Myelodysplastic Syndrome
10/15
10/15
NCT00568633: Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML

Terminated
3
58
US
Allogeneic HSCT, Hematopoietic stem cell transplantation (HSCT), Peripheral blood stem cell (PBSC) transplantation, Anti-thymocyte globulin (ATG), Thymoglobulin, Anti-thymocyte globulin (rabbit) (ATG), Cyclosporine (CSP), Ciclosporin, cyclosporin A, cyclosporin, Mycophenolate mofetil (MMF), Cellcept, Total lymphoid irradiation (TLI), Methylprednisolone sodium succinate, Solumedrol, Medrol, Depo-Medrol, P-Care D40, P-Care D80, Best standard care, Standard of Care (physician discretion), Regular medical care
Stanford University, Genzyme, a Sanofi Company
Leukemia, Myeloid, Leukemia, Acute Myeloid Leukemia (AML)
12/15
12/15
NCT01471444: Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Completed
3
256
US
Fludarabine, Fludarabine Phosphate, Fludara, Clofarabine, Clofarex, Clolar, Busulfan, Busulfex, Myleran, Thymoglobulin, ATG, Antithymocyte Globulin, Stem Cell Infusion, Bone marrow transplant, Tacrolimus, Prograf, Methotrexate
M.D. Anderson Cancer Center, Sanofi
Disorder Related to Bone Marrow Transplantation, Leukemia, Transplantation Infection
12/20
12/20
NCT04547049: A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies

Recruiting
3
160
RoW
Cytarabine, Busulfan, Cyclophosphamide, Me-CCNU, Rabbit antithymocyte globulin, Allogeneic HSCT, Cyclosporin A, Mycophenolate Mofetil, MTX
First Affiliated Hospital of Zhejiang University
Leukemia
09/25
12/25
OPTISAGE, NCT06083129: Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor

Not yet recruiting
3
324
NA
Grafalon, Thymoglobulin
Assistance Publique - Hôpitaux de Paris
GVHD
02/27
11/28
NCT05457556: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Recruiting
3
435
Canada, US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Busulfan, 1, 4-Bis[methanesulfonoxy]butane, BUS, Busilvex, Bussulfam, Busulfanum, Busulfex, Busulphan, CB 2041, CB-2041, Glyzophrol, GT 41, GT-41, Joacamine, Methanesulfonic Acid Tetramethylene Ester, Methanesulfonic acid, tetramethylene ester, Mielucin, Misulban, Misulfan, Mitosan, Myeleukon, Myeloleukon, Myelosan, Mylecytan, Myleran, Sulfabutin, Tetramethylene Bis(methanesulfonate), Tetramethylene bis[methanesulfonate], WR-19508, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Asta B 518, B-518, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamide Monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR- 138719, WR-138719, Echocardiography, EC, Fludarabine, Fluradosa, Haploidentical Hematopoietic Cell Transplantation, Haploidentical Stem Cell Transplantation, HLA-Haploidentical Hematopoietic Cell Transplantation, Stem Cell Transplantation, Haploidentical, Lapine T-Lymphocyte Immune Globulin, Anti-Thymocyte Globulin Rabbit, Antithymocyte Globulin Rabbit, Grafalon, Rabbit Anti-Human Thymocyte Globulin (RATG), Rabbit Anti-Thymocyte Globulin, Rabbit Antithymocyte Globulin, Rabbit ATG, Thymoglobulin, Lumbar Puncture, LP, Spinal Tap, Matched Unrelated Donor Hematopoietic Cell Transplantation, MUD-HCT, Melphalan, Alanine Nitrogen Mustard, CB-3025, L-PAM, L-Phenylalanine Mustard, L-Sarcolysin, L-Sarcolysin Phenylalanine mustard, L-Sarcolysine, Melphalanum, Phenylalanine Mustard, Phenylalanine Nitrogen Mustard, Sarcoclorin, Sarkolysin, WR-19813, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, CL 14377, CL-14377, Emtexate, Emthexat, Emthexate, Farmitrexat, Fauldexato, Folex, Folex PFS, Lantarel, Ledertrexate, Lumexon, Maxtrex, Medsatrexate, Metex, Methoblastin, Methotrexate LPF, Methotrexate Methylaminopterin, Methotrexatum, Metotrexato, Metrotex, Mexate, Mexate-AQ, MTX, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Mycophenolate Mofetil, CellCept, MMF, Myeloablative Conditioning, Myeloablation, Myeloablative, Myeloablative Cytoreduction, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Rituximab, ABP 798, BI 695500, C2B8 Monoclonal Antibody, Chimeric Anti-CD20 Antibody, CT-P10, IDEC-102, IDEC-C2B8, IDEC-C2B8 Monoclonal Antibody, Ikgdar, Mabtas, MabThera, Monoclonal Antibody IDEC-C2B8, PF-05280586, Riabni, Rituxan, Rituximab ABBS, Rituximab ARRX, Rituximab Biosimilar ABP 798, Rituximab Biosimilar BI 695500, Rituximab Biosimilar CT-P10, Rituximab Biosimilar GB241, Rituximab Biosimilar IBI301, Rituximab Biosimilar JHL1101, Rituximab Biosimilar PF-05280586, Rituximab Biosimilar RTXM83, Rituximab Biosimilar SAIT101, Rituximab Biosimilar SIBP-02, rituximab biosimilar TQB2303, Rituximab PVVR, Rituximab-abbs, Rituximab-arrx, Rituximab-pvvr, RTXM83, Ruxience, Truxima, T-Cell Depletion Therapy, T-Cell Depletion, T-Lymphocyte Depletion Therapy, Tacrolimus, FK 506, FK-506, Fujimycin, Hecoria, Prograf, Protopic, Tacforius, Thiotepa, 1,1',1''-Phosphinothioylidynetrisaziridine, Girostan, N,N', N''-Triethylenethiophosphoramide, Oncotiotepa, STEPA, Tepadina, TESPA, Tespamin, Tespamine, Thio-Tepa, Thiofosfamide, Thiofozil, Thiophosphamide, Thiophosphoamide, Thiophosphoramide, Thiotef, Tifosyl, TIO TEF, Tio-tef, Triethylene Thiophosphoramide, Triethylenethiophosphoramide, Tris(1-aziridinyl)phosphine sulfide, TSPA, WR 45312, Total-Body Irradiation, SCT_TBI, TBI, Total Body Irradiation, Whole Body, Whole Body Irradiation, Whole-Body Irradiation
Children's Oncology Group
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome
12/27
12/27
GLOBAL, NCT00354120 / 2005-000805-68: Thymoglobuline Versus Alemtuzumab in Patients Undergoing Allogeneic Transplant

Completed
2/3
121
Europe
Alentuzumab, Globulina antilinfocitaria
Gruppo Italiano Trapianto di Midollo Osseo
Acute Myeloblastic Leukemia, Lymphoblastic Leukemia, Myelodysplasia, Chronic Myeloid Leukemia, Myelofibrosis, Lympho-proliferative Diseases
08/11
08/11
NCT01015742: Unrelated Double Umbilical Cord Blood Units Transplantation

Unknown status
2/3
10
RoW
Stem cell Transplantation
Tehran University of Medical Sciences
Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, Acute, Leukemia, Myeloid, Chronic
12/12
01/13
NCT02707393 / 2008-000569-50: Allogeneic Stem Cell Transplantation for Children With CML

Completed
2/3
13
Europe, RoW
Fludarabine, Fludara, Thiotepa, Thioplex, TESPA, Melphalan, Alkeran, ATG, Thymoglobulin, Cyclosporine A, Sandimmune, Mycophenolate mofetil, CellCept, bone marrow or peripheral blood stem cells
St. Anna Kinderkrebsforschung
Chronic Myeloid Leukemia
12/20
12/20
FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting
2/3
1800
Europe, Canada, RoW
VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin
St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group
Acute Lymphoblastic Leukaemia
06/25
04/30

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