Leukemia  >>  Thymoglobulin (anti-thymocyte globulin (rabbit))  >>  Phase 2
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
NCT00506948: Thymoglobulin, Sirolimus and Mycophenolate Mofetil for Prevention of Acute Graft-Versus-Host Disease (GVHD)

Terminated
2
13
US
Mycophenolate Mofetil (MMF), CellCept, MMF, Thymoglobulin, Antithymocyte Globulin, rATG, ATG, Sirolimus, Rapamune, Stem Cell Transplant, hematopoietic stem cell transplantation, HSCT, transplantation
M.D. Anderson Cancer Center, Genzyme, a Sanofi Company
Hematological Malignancies, Myelodysplastic Syndrome, Leukemia, Lymphoma
10/10
10/10
NCT00469014: Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia

Completed
2
72
US
Clofarabine, Clofarex, Clolar, Busulfan, Busulfex, Myleran, Fludarabine, Fludarabine Phosphate, Fludara, Stem Cell Infusion, Bone Marrow Transplant, BMT, peripheral blood progenitor cells, PBPC, Unstimulated bone marrow transplant, bone marrow transplantation, ABM transplantations, autologous bone marrow transplantation, Thymoglobulin (ATG), Thymoglobulin, Antithymocyte Globulin, Filgrastim, G-CSF, Granulocyte colony-stimulating factor, GCSF
M.D. Anderson Cancer Center, Genzyme, a Sanofi Company
Acute Myeloid Leukemia, Myelodysplastic Syndrome, Chronic Myeloid Leukemia
03/13
03/13
NCT00709592: Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT

Completed
2
42
US
Thymoglobulin, anti-thymocyte globulin (rabbit), ATG, Genzyme, anti-thymocyte globulin, Rabbit, Rabbit-ATG, Total-Body Irradiation, Whole-Body Irradiation, Total Body Irradiation [TBI], Allogeneic PBSCT or BMT, PBPC transplantation, Peripheral Blood Progenitor Cell Transplantation, Peripheral Blood Stem Cell Transplantation [Allogenic PBSCT], Allogeneic Bone Marrow Transplantation [BMT], Allogeneic BMT, Allogeneic Hematopoietic Stem Cell Transplantation, HSCT, Tacrolimus, Fujimycin, Hecoria, Prograf, Protopic, Mycophenolate Mofetil, CellCept, MMF
Virginia Commonwealth University, Genzyme, a Sanofi Company
Non-Hodgkin's Lymphoma, Leukemia, Multiple Myeloma, Acute Myeloid Leukemia, Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome
02/14
06/17
NCT00813124: Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML)

Completed
2
24
US
Fludarabine, Fludarabine Phosphate, Busulfan, Busulfex, Myleran, Thymoglobulin, Antithymocyte globulin, ATG, Azacitidine, 5-Azacitidine, 5-Aza, 5-AZC, Ladakamycin, NSC-102816, Vidaza, Stem Cell Transplant, allotx, allogeneic stem cell transplantation
M.D. Anderson Cancer Center, National Cancer Institute (NCI), Celgene Corporation
Stem Cell Transplantation, Leukemia
09/14
09/14
NCT02500550 / 2015-002821-20: Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Checkmark AIR-008 study for GVHD
Jan 2018 - Jan 2018: AIR-008 study for GVHD
Checkmark Safety data readout from CR-AIR-008 trial for GVHD in patients with hematologic malignancies post-HSCT
Dec 2016 - Dec 2016: Safety data readout from CR-AIR-008 trial for GVHD in patients with hematologic malignancies post-HSCT
Completed
2
15
Europe, Canada, RoW
ATIR101, Haploidentical hematopoietic stem cell transplantation (HSCT), TBI regime, Non-TBI regime
Kiadis Pharma
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome
07/18
12/18
NCT00899431: Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL)

Terminated
2
39
US
Lenalidomide, CC-5013, Revlimid, Fludarabine, Fludara, Fludarabine Phosphate, Rituximab, Rituxan, Thymoglobulin, ATG, rabbit anti-thymocyte globulin, Stem Cell Transplantation, SCT, Nonmyeloablative Stem Cell Transplantation, Bendamustine, Bendamustine Hydrochloride, Bendamustine HCL, CEP-18083, SDX-105, Treanda, Allopurinol, Lopurin, Zurinol, Zyloprim
M.D. Anderson Cancer Center, Celgene Corporation
Chronic Lymphocytic Leukemia
10/18
10/18
NCT01490723: Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT)

Completed
2
20
US
Rituximab, Rituxan, 111In Ibritumomab, Zevalin, Planar Scintigraphy Imaging, 90Y IbritumomabTiuxetan, Fludarabine, Fludarabine Phosphate, Fludara, Bendamustine, Bendamustine Hydrochoride, Bendamustine HCL, CEP-18083, SDX-105, Treanda, Thymoglobulin, ATG, Antithymocyte Globulin, Tacrolimus, Prograf, Methotrexate, Mycophenolate, MMF, Mycophenolate Mofetil, CellCept, G-CSF, Filgrastim, Neupogen, Stem Cell Transplantation, Allogeneic transplantation
M.D. Anderson Cancer Center, Spectrum Pharmaceuticals, Inc
Leukemia, Lymphoma
04/19
04/19
NCT04202835: ATG Plus PTCy vs ATG for CGVHD Prophylaxis

Recruiting
2
80
Canada, RoW
Cyclophosphamide, Anti-Thymocyte globulin (rabbit), Thymoglobulin
McMaster University, Cell Therapy Transplant Canada, Sanofi, Ozmosis Research Inc.
Acute Leukemia, Myelodysplasia, Chronic Graft-versus-host-disease
10/24
12/24
NCT00822770: Plerixafor and Granulocyte Colony-stimulating Factor (G-CSF) With Busulfan, Fludarabine and Thymoglobulin

Completed
1/2
47
US
Plerixafor, AMD3100, Filgrastim, G-CSF, Neupogen, Fludarabine, Fludarabine Phosphate, Fludara, Busulfan, Busulfex™, Myleran®, Allogeneic blood stem cell transplant, Bone Marrow Transplantation, Blood Stem Cell Transplantation, ATG (Thymoglobulin), Antithymocyte globulin
M.D. Anderson Cancer Center, Genzyme, a Sanofi Company
Stem Cell Transplantation, Leukemia
10/12
10/12
NCT00396968: AMD3100 With Busulfan, Fludarabine and Thymoglobulin for Allogeneic Stem Cell Transplant for AML and MDS

Withdrawn
1/2
0
US
AMD3100, Allogeneic Stem Cell Transplantation
Genzyme, a Sanofi Company, AnorMED
Acute Myelogenous Leukemia, Myelodysplastic Syndromes
 
 
NCT00448357: Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen

Completed
1/2
54
US
rabbit anti-thymocyte globulin (ATG), therapeutic allogeneic lymphocytes, busulfan, fludarabine phosphate, tacrolimus, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, methotrexate
UNC Lineberger Comprehensive Cancer Center, National Cancer Institute (NCI), Otsuka America Pharmaceutical
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
11/15
11/15

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