Syndrome  >>  Thymoglobulin (anti-thymocyte globulin (rabbit))  >>  Phase 2
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38 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
NCT01056614: Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies

Completed
2
23
US
fludarabine phosphate, 2-F-ara-AMP, Beneflur, Fludara, busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, tacrolimus, FK 506, Prograf, methotrexate, amethopterin, Folex, methylaminopterin, Mexate, MTX, peripheral blood stem cell transplantation, PBPC transplantation, PBSC transplantation, peripheral blood progenitor cell transplantation, transplantation, peripheral blood stem cell, allogeneic hematopoietic stem cell transplantation, laboratory biomarker analysis
Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI)
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Phase Chronic Myelogenous Leukemia, de Novo Myelodysplastic Syndromes, Hematopoietic/Lymphoid Cancer, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia
08/05
04/16
NCT00346359: Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancer

Completed
2
40
US
anti-thymocyte globulin, busulfan, fludarabine phosphate, methotrexate, tacrolimus, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation
Fred Hutchinson Cancer Center, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
 
11/07
NCT00611351: Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer

Completed
2
5
US
anti-thymocyte globulin, immunosuppressant, busulfan, Busulfex, Myleran, cyclophosphamide, cytophosphane, mycophenolate mofetil, CellCept, tacrolimus, Protopic, Envarsus XR, Astagraf XL, polymerase chain reaction, polymorphism analysis, flow cytometry, laboratory biomarker analysis, pharmacogenomic studies, pharmacological study, allogeneic bone marrow transplantation, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation
University of Nebraska, National Cancer Institute (NCI)
Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Secondary Myelofibrosis
02/08
09/08
NCT00582933: Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor

Completed
2
96
US
BUSULFAN, MELPHALAN, FLUDARABINE, G-CSF
Memorial Sloan Kettering Cancer Center
Leukemia, Myelodysplastic Syndrome, Non-Hodgkin's Lymphoma, Allogeneic Marrow Transplant
04/08
04/09
NCT00176917: Stem Cell Transplantation for Hurler

Completed
2
41
US
Stem Cell Transplant, Bone Marrow Transplant, Busulfan, Cyclophosphamide, ATG, Busulfex, Cytoxan, Thymoglobulin
Masonic Cancer Center, University of Minnesota
Mucopolysaccharidosis I, Mucopolysaccharidosis VI, Mannosidosis, Mucolipidosis Type II (I-cell Disease)
05/08
05/10
NCT00593645: Clofarabine, Cytarabine, and Thymoglobulin for Allogeneic Transplantation

Terminated
2
7
US
Clofarabine, Clolar, Cytarabine, Ara-C, Cytosar, Thymoglobulin, Anti-thymocyte globulin, Stem cell infusion, Stem cell transplant, Hematopoietic stem cell transplant, Peripheral blood stem cell transplant, Bone marrow transplant
Washington University School of Medicine
Myelodysplastic Syndromes, Acute Myeloid Leukemia
12/08
07/09
RISE, NCT00542828 / 2007-002532-28: Rabbit Anti-thymocyte Globulin in the Treatment of Patients With Low to Intermediate-1 Risk Myelodysplastic Syndrome

Terminated
2
16
Europe
Thymoglobulin®, Rabbit Anti-thymocyte Globulin (rATG), Rabbbit Anti-human thymocyte immunoglobulin
Genzyme, a Sanofi Company
Myelodysplastic Syndrome (MDS)
05/09
07/09
NCT00038857: Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases

Completed
2
29
US
Megadose of CD34 Selected Progenitor Cells, Melphalan, Alkeran, Thiotepa, Fludarabine, Fludarabine Phosphate, Fludara, Rabbit ATG, Rabbit antithymocyte globulin, ATG, rATG, Genzyme, Thymoglobulin
M.D. Anderson Cancer Center
Leukemia, Lymphoma
06/09
06/09
NCT00795132: Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignancies

Completed
2
47
US
Busulfan, Busulfex, Anti-Thymocyte Globulin, Thymoglobulin® [Anti-thymocyte Globulin, (Rabbit)], Fludarabine, Fludara, Cyclosporine, Mycophenolate mofetil, MMF, CellCept
University of Utah
Acute Leukaemia, Chronic Disease, Leukemia, Myelodysplasia, Lymphoma
07/09
07/09
NCT00787761: Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Completed
2
24
US
anti-thymocyte globulin, Thymoglobulin, ATG, busulfan, cyclophosphamide, fludarabine phosphate, Fludara, methotrexate, Amethopterin, MTX, tacrolimus, Prograf, FK506, nonmyeloablative allogeneic HSCT
Northside Hospital, Inc., Blood and Marrow Transplant Group of Georgia
Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
07/10
05/12
NCT00392782: Donor Stem Cell Transplant in Treating Patients With Myeloid Cancer or Other Disease

Terminated
2
24
US
anti-thymocyte globulin, ATG, fludarabine phosphate, Fludara, thiotepa, peripheral blood stem cell transplantation, PBSC, total-body irradiation, TBI
Masonic Cancer Center, University of Minnesota, Center for International Blood and Marrow Transplant Research
Leukemia, Myelodysplastic Syndromes
05/11
05/11
FB-ATG, NCT00915811 / 2006-004452-20: Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin

Terminated
2
20
Europe
Fludarabine, Busulphan, Thymoglobuline (Anti-thymocyte globulin [rabbit]) - Genzyme, Haematopoietic stem cell infusion
King's College Hospital NHS Trust
Myelodysplastic Syndromes, Leukemia, Myeloid, Acute
06/11
06/11
NCT00589563: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

Completed
2
32
US
anti-thymocyte globulin, cyclophosphamide, etoposide, fludarabine phosphate, melphalan, methotrexate, sirolimus, tacrolimus, allogeneic hematopoietic stem cell transplantation, hematopoietic stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation
City of Hope Medical Center, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition, Secondary Myelofibrosis, Small Intestine Cancer
02/12
02/12
NCT00916045 / 2007-001657-26: Pilot Study of Unrelated Cord Blood Transplantation

Terminated
2
40
Europe
Thiotepa, Fludarabine, Intravenous busulphan, Busilvex, Thymoglobulin, Ciclosporin, Mycophenolate mofetil (MMF), Cyclophosphamide, Radiotherapy, Melphalan
King's College Hospital NHS Trust
Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Leukemia, Lymphoblastic, Acute, Lymphoma, Non-Hodgkin, Hodgkin Disease, Chronic Lymphocytic Leukemia
03/12
03/12
NCT00806598: Thymoglobulin and Cyclosporine in Patients With Aplastic Anemia or Myelodysplastic Syndrome

Completed
2
53
US
Thymoglobulin, ATG, Antithymocyte globulin, Cyclosporine, CYA, Sandimmune, Cyclosporine A, Methylprednisolone, Duralone®, Medralone®, Medrol®, M-Prednisol®, Solu-Medrol®, G-CSF, Neupogen®, Granulocyte - Colony Stimulating Factor
M.D. Anderson Cancer Center, Genzyme, a Sanofi Company
Myelodysplastic Syndrome, Aplastic Anemia
06/12
06/12
NCT01044745: Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

Terminated
2
20
US
rituximab, IDEC-C2B8, IDEC-C2B8 monoclonal antibody, Mabthera, MOAB IDEC-C2B8, Rituxan, mycophenolate mofetil, Cellcept, MMF, tacrolimus, FK 506, Prograf, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, allogeneic hematopoietic stem cell transplantation, laboratory biomarker analysis, graft versus host disease prophylaxis/therapy, prophylaxis/therapy, graft versus host disease, prophylaxis/therapy, GVHD, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, fludarabine phosphate, 2-F-ara-AMP, Beneflur, Fludara, busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, total-body irradiation, TBI, graft-versus-tumor induction therapy, graft versus host disease induction, graft versus tumor induction, immunosuppressive therapy, immunosuppression
University of Nebraska, National Cancer Institute (NCI)
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Blastic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, de Novo Myelodysplastic Syndromes, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Graft Versus Host Disease, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Splenic Marginal Zone Lymphoma, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Adult T-cell Leukemia/Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Cutaneous T-cell Non-Hodgkin Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Mycosis Fungoides/Sezary Syndrome, Stage I Small Lymphocytic Lymphoma, Stage II Adult T-cell Leukemia/Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage II Cutaneous T-cell Non-Hodgkin Lymphoma, Stage II Mycosis Fungoides/Sezary Syndrome, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Mycosis Fungoides/Sezary Syndrome, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Mycosis Fungoides/Sezary Syndrome, Stage IV Small Lymphocytic Lymphoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia, Waldenström Macroglobulinemia
12/12
10/17
NCT01116232: Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

Terminated
2
4
US
anti-thymocyte globulin, rituximab, Rituxan®, sirolimus, Rapamune®, tacrolimus, Prograf, laboratory biomarker analysis, allogeneic hematopoietic stem cell transplantation, management of therapy complications, peripheral blood stem cell transplantation
Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
05/13
06/13
Cloric, NCT00863148: Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL)

Completed
2
30
Europe
Clofarabine in combination with IV busulfan and ATG
Nantes University Hospital
MDS, AML, ALL, BAL
06/13
06/13
NCT01246206: Tacrolimus and Thymoglobulin, as GvHD Prophylaxis in Patients Undergoing Related Donor HCT

Completed
2
21
US
Tacrolimus and Thymoglobulin, PROGRAF®
Barbara Ann Karmanos Cancer Institute
Hematological Malignancies
10/13
10/13
NCT00720629: Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation

Terminated
2
8
US
Visilizumab, Tacrolimus, Methotrexate, Antithymocyte globulin (ATG), Thymoglobulin-ATG
H. Lee Moffitt Cancer Center and Research Institute, National Institutes of Health (NIH), National Cancer Institute (NCI)
Graft Versus Host Disease
12/13
12/13
NCT01622556: Conditioning Treatment With Umbilical Cord Blood Transplant for Hematologic Malignancies

Terminated
2
6
US
Fludarabine, Busulfan, Thymoglobulin, Total Body Irradiation, Umbilical Cord Blood
University of Virginia
Hematologic Malignancies
02/14
01/17
NCT00709592: Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT

Completed
2
42
US
Thymoglobulin, anti-thymocyte globulin (rabbit), ATG, Genzyme, anti-thymocyte globulin, Rabbit, Rabbit-ATG, Total-Body Irradiation, Whole-Body Irradiation, Total Body Irradiation [TBI], Allogeneic PBSCT or BMT, PBPC transplantation, Peripheral Blood Progenitor Cell Transplantation, Peripheral Blood Stem Cell Transplantation [Allogenic PBSCT], Allogeneic Bone Marrow Transplantation [BMT], Allogeneic BMT, Allogeneic Hematopoietic Stem Cell Transplantation, HSCT, Tacrolimus, Fujimycin, Hecoria, Prograf, Protopic, Mycophenolate Mofetil, CellCept, MMF
Virginia Commonwealth University, Genzyme, a Sanofi Company
Non-Hodgkin's Lymphoma, Leukemia, Multiple Myeloma, Acute Myeloid Leukemia, Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome
02/14
06/17
NCT00185796: TLI & ATG for Non-Myeloablative Allogeneic Transplantation for MDS and MPD

Completed
2
77
US
Total Lymphoid Irradiation (TLI), Anti-Thymocyte Globulin as Conditioning (ATG)
Stanford University, National Institutes of Health (NIH)
Myeloproliferative Disorders, Blood Cancer, Myelodysplastic Syndromes
04/14
02/15
NCT00691015: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant

Completed
2
48
US
rituximab, Rituxan, MabThera, Zytux, busulfan, Busulfex, Myleran, carmustine, Bicnu, Gliadel, cyclophosphamide, Cytoxan, Cytoxan Lyophilized, Neosar, cytarabine, Depocyt, etoposide, Etopophos, Toposar, fludarabine phosphate, Fludara®, melphalan, Alkeran, total body irradiation (TBI), radiotherapy, anti-thymocyte globulin IV, Thymoglobulin
Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
04/14
04/14
NCT00617929: Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant

Terminated
2
12
US
anti-thymocyte globulin, Thymoglobulin®, rituximab, Rituxan(R), clofarabine, CLOLAR™, stem cell transplantation
Masonic Cancer Center, University of Minnesota
Cancer
10/14
10/15
NCT01745913: Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

Terminated
2
2
US
CliniMACS® CD34 Reagent System, Miltenyi CliniMACS® device, Fludarabine, Melphalan, Rabbit ATG, rATG, Double Umbilical Cord Blood Transplantation, UCB SCT, Haplo-Identical Cord Transplantation, Haplo-cord transplant
Weill Medical College of Cornell University
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Acute Lymphocytic Leukemia, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
04/15
04/15
NCT01082133: Multicenter Transplant Study for Fanconi Anemia

Completed
2
45
US
Chemotherapy, Miltenyi CliniMACS
Children's Hospital Medical Center, Cincinnati
Fanconi Anemia
07/15
07/15
NCT01093586: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Completed
2
14
US
double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration, fluorescence in situ hybridization, fluorescence in situ hybridization (FISH), busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, Myelosan, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, Enduxan, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, methylprednisolone, A-MethaPred, Depo-Medrol, Medrol, MePRDL, Solu-Medrol, Wyacort, cyclosporine, 27-400, ciclosporin, cyclosporin, cyclosporin A, CYSP, Sandimmune, mycophenolate mofetil, Cellcept, MMF, flow cytometry, allogeneic hematopoietic stem cell transplantation
Case Comprehensive Cancer Center
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Erythroleukemia (M6a), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Adult Pure Erythroid Leukemia (M6b), B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Burkitt Lymphoma, Childhood Acute Erythroleukemia (M6), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Minimally Differentiated Myeloid Leukemia (M0), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Juvenile Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Previously Treated Myelodysplastic Syndromes, Prolymphocytic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Secondary Myelofibrosis, Splenic Marginal Zone Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic Leukemia, T-cell Adult Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic Leukemia, T-cell Large Granular Lymphocyte Leukemia, Waldenstrom Macroglobulinemia
12/15
12/15
NCT01621477: T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

Terminated
2
34
US
clofarabine, Cl-F-Ara-A, CAFdA, Clofarex, Clolar(TM), cytarabine, Ara-C, busulfan, Myleran(R), Busulfex, Plerixafor, AMD3100, Mozobil(R), cyclophosphamide, Cytoxan, antithymocyte globulin (rabbit), Rabbit ATG, Rabbit Thymoglobulin(R), stem cells, HSC infusion, Tacrolimus, FK506, Prograf(R), Protonic(R), mycophenolate mofetil, MMF, CellCept(R)
St. Jude Children's Research Hospital, Assisi Foundation
Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Hodgkin or Non-Hodgkin Lymphoma, Sarcoma, Myeloid
12/15
12/15
NCT00593554: Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies

Terminated
2
9
US
Total Body Irradiation, Thiotepa, Fludarabine, Rabbit ATG, Antithymocyte globulin, Thymoglobulin, Palifermin, Recombinant human keratinocyte growth factor, Kepivance
Sherif S. Farag
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplasia, Chronic Myeloid Leukemia
08/16
07/17
NCT01566656: Allogeneic Hematopoietic Stem Cell Transplantation Using a Non-myeloablative Preparative Regimen of Total Lymphoid Irradiation and Anti-thymocyte Globulin for Older Patients With Relapsed Lymphoid Malignancies

Completed
2
15
Europe
total lymphoid irradiation and anti-thymocyte globulin
Nantes University Hospital
Haemato-lymphoid Malignancies or Syndromes in Whom Allogeneic Stem Cell Transplantation is Warranted
11/16
11/16
NCT00038831: Allo Transplantation With Mylotarg, Fludarabine and Melphalan for AML, CML and MDS

Completed
1/2
47
US
Mylotarg, Gemtuzumab, Gemtuzumab ozogamicin, Fludarabine, Fludara, Fludarabine Phosphate, Melphalan, Alkeran, Anti-thymocyte globulin, Rabbit anti-thymocyte globulin, Anti-thymocyte globulin (ATG), Stem cell transplant, alloBMT, Allo PBSCT
M.D. Anderson Cancer Center
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Chronic Lymphocytic Leukemia
03/05
10/06
NCT00054340: Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder

Completed
1/2
US
anti-thymocyte globulin, busulfan, cyclophosphamide, cyclosporine, methotrexate, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation
Fred Hutchinson Cancer Center, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
 
09/06
NCT00801931: Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders

Terminated
1/2
1
US
Alemtuzumab, Lemtrada, Campath, Total Body Irradiation, TBI, Melphalan, Alkeran, Busulfan, Busulfex, Myleran, Phenytoin, Fosphenytoin, Dilantin, Fludarabine, Fludara, Cyclophosphamide, Cytoxan, Neosar, Horse Antithymocyte Globulin, Atgam, ATG[horse], Rabbit Antithymocyte Globulin, Thymoglobulin, Thiotepa, Tepadina
Columbia University
Leukemia, Lymphoma, Neuroblastoma, Immunodeficiencies, Anemia
05/09
05/09
NCT00885833: Study of Reduced Toxicity Myeloablative Conditioning Regimen for Wiskott-Aldrich Syndrome (WAS)

Completed
1/2
5
RoW
Fludarabine, Busulfan, Thymoglobulin
The Korean Society of Pediatric Hematology Oncology
Wiskott-Aldrich Syndrome
03/12
03/12
NCT01050764: Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells

Terminated
1/2
10
US
Regulatory T-cells, T-reg cells, Conventional T-cells, T-con cells, Melphalan, L-PAM, L-Sarcolysin, Phenylalanine Mustard, Thiotepa, thiophosphamide, TESPA, TSPA, Fludarabine, Fludarabine phosphate, Fludarabine 5'-monophosphate, FAMP, Fludara, Anti-thymocyte globulin, rabbit, Thymoglobulin, rATG, CliniMACS CD34 Reagent System
Everett Meyer, Doris Duke Charitable Foundation
Leukemia, Acute, Chronic Myelogenous Leukemia (CML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL), Chronic Lymphocytic Leukemia (CLL), Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL)
08/12
06/14
NCT00396968: AMD3100 With Busulfan, Fludarabine and Thymoglobulin for Allogeneic Stem Cell Transplant for AML and MDS

Withdrawn
1/2
0
US
AMD3100, Allogeneic Stem Cell Transplantation
Genzyme, a Sanofi Company, AnorMED
Acute Myelogenous Leukemia, Myelodysplastic Syndromes
 
 
NCT00448357: Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen

Completed
1/2
54
US
rabbit anti-thymocyte globulin (ATG), therapeutic allogeneic lymphocytes, busulfan, fludarabine phosphate, tacrolimus, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, methotrexate
UNC Lineberger Comprehensive Cancer Center, National Cancer Institute (NCI), Otsuka America Pharmaceutical
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
11/15
11/15

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