Lymphoproliferative Disorders  >>  Thymoglobulin (anti-thymocyte globulin (rabbit))  >>  Phase 2
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13 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
NCT00378768: Antithymocyte Globulin in Treating Patients Undergoing Stem Cell Transplant for Multiple Myeloma

Completed
2
12
US
anti-thymocyte globulin
Fred Hutchinson Cancer Center, National Cancer Institute (NCI)
Multiple Myeloma and Plasma Cell Neoplasm
 
06/07
NCT00133367: Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

Completed
2
32
US
Tacrolimus, Sirolimus, G-CSF, Antithymocyte globulin, Thymoglobulin, Fludarabine, Melphalan
Massachusetts General Hospital, Dana-Farber Cancer Institute
Multiple Myeloma, Non-Hodgkin's Lymphoma, Hodgkin's Disease, Myelogenous Leukemia, Lymphoblastic Leukemia
11/07
11/11
NCT00635024: Anti-thymocyte Globulin and Melphalan in Treating Patients With Relapsed Multiple Myeloma

Terminated
2
1
US
anti-thymocyte globulin, melphalan
Mayo Clinic, National Cancer Institute (NCI)
Multiple Myeloma and Plasma Cell Neoplasm
07/08
11/10
NCT00787761: Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Completed
2
24
US
anti-thymocyte globulin, Thymoglobulin, ATG, busulfan, cyclophosphamide, fludarabine phosphate, Fludara, methotrexate, Amethopterin, MTX, tacrolimus, Prograf, FK506, nonmyeloablative allogeneic HSCT
Northside Hospital, Inc., Blood and Marrow Transplant Group of Georgia
Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
07/10
05/12
NCT00589563: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

Completed
2
32
US
anti-thymocyte globulin, cyclophosphamide, etoposide, fludarabine phosphate, melphalan, methotrexate, sirolimus, tacrolimus, allogeneic hematopoietic stem cell transplantation, hematopoietic stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation
City of Hope Medical Center, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition, Secondary Myelofibrosis, Small Intestine Cancer
02/12
02/12
NCT00916045 / 2007-001657-26: Pilot Study of Unrelated Cord Blood Transplantation

Terminated
2
40
Europe
Thiotepa, Fludarabine, Intravenous busulphan, Busilvex, Thymoglobulin, Ciclosporin, Mycophenolate mofetil (MMF), Cyclophosphamide, Radiotherapy, Melphalan
King's College Hospital NHS Trust
Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Leukemia, Lymphoblastic, Acute, Lymphoma, Non-Hodgkin, Hodgkin Disease, Chronic Lymphocytic Leukemia
03/12
03/12
NCT01044745: Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

Terminated
2
20
US
rituximab, IDEC-C2B8, IDEC-C2B8 monoclonal antibody, Mabthera, MOAB IDEC-C2B8, Rituxan, mycophenolate mofetil, Cellcept, MMF, tacrolimus, FK 506, Prograf, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, allogeneic hematopoietic stem cell transplantation, laboratory biomarker analysis, graft versus host disease prophylaxis/therapy, prophylaxis/therapy, graft versus host disease, prophylaxis/therapy, GVHD, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, fludarabine phosphate, 2-F-ara-AMP, Beneflur, Fludara, busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, total-body irradiation, TBI, graft-versus-tumor induction therapy, graft versus host disease induction, graft versus tumor induction, immunosuppressive therapy, immunosuppression
University of Nebraska, National Cancer Institute (NCI)
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Blastic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, de Novo Myelodysplastic Syndromes, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Graft Versus Host Disease, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Splenic Marginal Zone Lymphoma, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Adult T-cell Leukemia/Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Cutaneous T-cell Non-Hodgkin Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Mycosis Fungoides/Sezary Syndrome, Stage I Small Lymphocytic Lymphoma, Stage II Adult T-cell Leukemia/Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage II Cutaneous T-cell Non-Hodgkin Lymphoma, Stage II Mycosis Fungoides/Sezary Syndrome, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Mycosis Fungoides/Sezary Syndrome, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Mycosis Fungoides/Sezary Syndrome, Stage IV Small Lymphocytic Lymphoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia, Waldenström Macroglobulinemia
12/12
10/17
NCT01116232: Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

Terminated
2
4
US
anti-thymocyte globulin, rituximab, Rituxan®, sirolimus, Rapamune®, tacrolimus, Prograf, laboratory biomarker analysis, allogeneic hematopoietic stem cell transplantation, management of therapy complications, peripheral blood stem cell transplantation
Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
05/13
06/13
NCT01534143: High Dose Busulfan and Bortezomib in Treating Patients With High Risk Multiple Myeloma Undergoing Stem Cell Transplant

Terminated
2
1
US
pharmacological study, pharmacological studies, tacrolimus, FK 506, Prograf, sirolimus, AY 22989, Rapamune, rapamycin, SLM, anti-thymocyte globulin, ATG, ATGAM, lymphocyte immune globulin, Thymoglobulin, fludarabine phosphate, 2-F-ara-AMP, Beneflur, Fludara, busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, bortezomib, LDP 341, MLN341, VELCADE, allogeneic hematopoietic stem cell transplantation, laboratory biomarker analysis
Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI)
Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
05/13
05/13
AHCTALL, NCT01037764: Donor-specific Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (ALL)

Terminated
2
100
RoW
alloHCT, allogeneic hematopoietic stem cell transplantation
Asan Medical Center
Acute Lymphoid Leukemia
12/14
12/16
NCT01621477: T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

Terminated
2
34
US
clofarabine, Cl-F-Ara-A, CAFdA, Clofarex, Clolar(TM), cytarabine, Ara-C, busulfan, Myleran(R), Busulfex, Plerixafor, AMD3100, Mozobil(R), cyclophosphamide, Cytoxan, antithymocyte globulin (rabbit), Rabbit ATG, Rabbit Thymoglobulin(R), stem cells, HSC infusion, Tacrolimus, FK506, Prograf(R), Protonic(R), mycophenolate mofetil, MMF, CellCept(R)
St. Jude Children's Research Hospital, Assisi Foundation
Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Hodgkin or Non-Hodgkin Lymphoma, Sarcoma, Myeloid
12/15
12/15
NCT00385788: Allogeneic Blood Stem Cell Transplantation and Adoptive Immunotherapy for Hodgkin's Disease

Completed
2
52
US
Gemcitabine, Gemzar, Gemcitabine hydrochloride, Fludarabine, Fludarabine Phosphate, Fludara, Melphalan, Antithymocyte Globulin, ATG, Thymoglobulin, Allogeneic Stem Cell Infusion, AST, Stem Cell Transplantation, SCT, Tacrolimus, Prograf, Filgrastim (G-CSF), Granul, Methotrexate, MTX
M.D. Anderson Cancer Center
Hodgkin's Disease
08/16
08/16
NCT00593554: Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies

Terminated
2
9
US
Total Body Irradiation, Thiotepa, Fludarabine, Rabbit ATG, Antithymocyte globulin, Thymoglobulin, Palifermin, Recombinant human keratinocyte growth factor, Kepivance
Sherif S. Farag
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplasia, Chronic Myeloid Leukemia
08/16
07/17

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