Hodgkin Disease  >>  Thymoglobulin (anti-thymocyte globulin (rabbit))  >>  Phase 2
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14 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
NCT00133367: Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

Completed
2
32
US
Tacrolimus, Sirolimus, G-CSF, Antithymocyte globulin, Thymoglobulin, Fludarabine, Melphalan
Massachusetts General Hospital, Dana-Farber Cancer Institute
Multiple Myeloma, Non-Hodgkin's Lymphoma, Hodgkin's Disease, Myelogenous Leukemia, Lymphoblastic Leukemia
11/07
11/11
NCT00611351: Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer

Completed
2
5
US
anti-thymocyte globulin, immunosuppressant, busulfan, Busulfex, Myleran, cyclophosphamide, cytophosphane, mycophenolate mofetil, CellCept, tacrolimus, Protopic, Envarsus XR, Astagraf XL, polymerase chain reaction, polymorphism analysis, flow cytometry, laboratory biomarker analysis, pharmacogenomic studies, pharmacological study, allogeneic bone marrow transplantation, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation
University of Nebraska, National Cancer Institute (NCI)
Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Secondary Myelofibrosis
02/08
09/08
NCT00787761: Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Completed
2
24
US
anti-thymocyte globulin, Thymoglobulin, ATG, busulfan, cyclophosphamide, fludarabine phosphate, Fludara, methotrexate, Amethopterin, MTX, tacrolimus, Prograf, FK506, nonmyeloablative allogeneic HSCT
Northside Hospital, Inc., Blood and Marrow Transplant Group of Georgia
Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
07/10
05/12
NCT00589563: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

Completed
2
32
US
anti-thymocyte globulin, cyclophosphamide, etoposide, fludarabine phosphate, melphalan, methotrexate, sirolimus, tacrolimus, allogeneic hematopoietic stem cell transplantation, hematopoietic stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation
City of Hope Medical Center, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition, Secondary Myelofibrosis, Small Intestine Cancer
02/12
02/12
NCT00916045 / 2007-001657-26: Pilot Study of Unrelated Cord Blood Transplantation

Terminated
2
40
Europe
Thiotepa, Fludarabine, Intravenous busulphan, Busilvex, Thymoglobulin, Ciclosporin, Mycophenolate mofetil (MMF), Cyclophosphamide, Radiotherapy, Melphalan
King's College Hospital NHS Trust
Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Leukemia, Lymphoblastic, Acute, Lymphoma, Non-Hodgkin, Hodgkin Disease, Chronic Lymphocytic Leukemia
03/12
03/12
NCT01116232: Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

Terminated
2
4
US
anti-thymocyte globulin, rituximab, Rituxan®, sirolimus, Rapamune®, tacrolimus, Prograf, laboratory biomarker analysis, allogeneic hematopoietic stem cell transplantation, management of therapy complications, peripheral blood stem cell transplantation
Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
05/13
06/13
NCT01246206: Tacrolimus and Thymoglobulin, as GvHD Prophylaxis in Patients Undergoing Related Donor HCT

Completed
2
21
US
Tacrolimus and Thymoglobulin, PROGRAF®
Barbara Ann Karmanos Cancer Institute
Hematological Malignancies
10/13
10/13
NCT01622556: Conditioning Treatment With Umbilical Cord Blood Transplant for Hematologic Malignancies

Terminated
2
6
US
Fludarabine, Busulfan, Thymoglobulin, Total Body Irradiation, Umbilical Cord Blood
University of Virginia
Hematologic Malignancies
02/14
01/17
NCT00709592: Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT

Completed
2
42
US
Thymoglobulin, anti-thymocyte globulin (rabbit), ATG, Genzyme, anti-thymocyte globulin, Rabbit, Rabbit-ATG, Total-Body Irradiation, Whole-Body Irradiation, Total Body Irradiation [TBI], Allogeneic PBSCT or BMT, PBPC transplantation, Peripheral Blood Progenitor Cell Transplantation, Peripheral Blood Stem Cell Transplantation [Allogenic PBSCT], Allogeneic Bone Marrow Transplantation [BMT], Allogeneic BMT, Allogeneic Hematopoietic Stem Cell Transplantation, HSCT, Tacrolimus, Fujimycin, Hecoria, Prograf, Protopic, Mycophenolate Mofetil, CellCept, MMF
Virginia Commonwealth University, Genzyme, a Sanofi Company
Non-Hodgkin's Lymphoma, Leukemia, Multiple Myeloma, Acute Myeloid Leukemia, Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome
02/14
06/17
NCT00691015: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant

Completed
2
48
US
rituximab, Rituxan, MabThera, Zytux, busulfan, Busulfex, Myleran, carmustine, Bicnu, Gliadel, cyclophosphamide, Cytoxan, Cytoxan Lyophilized, Neosar, cytarabine, Depocyt, etoposide, Etopophos, Toposar, fludarabine phosphate, Fludara®, melphalan, Alkeran, total body irradiation (TBI), radiotherapy, anti-thymocyte globulin IV, Thymoglobulin
Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
04/14
04/14
NCT00617929: Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant

Terminated
2
12
US
anti-thymocyte globulin, Thymoglobulin®, rituximab, Rituxan(R), clofarabine, CLOLAR™, stem cell transplantation
Masonic Cancer Center, University of Minnesota
Cancer
10/14
10/15
NCT01745913: Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

Terminated
2
2
US
CliniMACS® CD34 Reagent System, Miltenyi CliniMACS® device, Fludarabine, Melphalan, Rabbit ATG, rATG, Double Umbilical Cord Blood Transplantation, UCB SCT, Haplo-Identical Cord Transplantation, Haplo-cord transplant
Weill Medical College of Cornell University
Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Acute Lymphocytic Leukemia, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
04/15
04/15
NCT00385788: Allogeneic Blood Stem Cell Transplantation and Adoptive Immunotherapy for Hodgkin's Disease

Completed
2
52
US
Gemcitabine, Gemzar, Gemcitabine hydrochloride, Fludarabine, Fludarabine Phosphate, Fludara, Melphalan, Antithymocyte Globulin, ATG, Thymoglobulin, Allogeneic Stem Cell Infusion, AST, Stem Cell Transplantation, SCT, Tacrolimus, Prograf, Filgrastim (G-CSF), Granul, Methotrexate, MTX
M.D. Anderson Cancer Center
Hodgkin's Disease
08/16
08/16
NCT00448357: Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen

Completed
1/2
54
US
rabbit anti-thymocyte globulin (ATG), therapeutic allogeneic lymphocytes, busulfan, fludarabine phosphate, tacrolimus, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, methotrexate
UNC Lineberger Comprehensive Cancer Center, National Cancer Institute (NCI), Otsuka America Pharmaceutical
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
11/15
11/15

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