| Zynrelef (bupivacaine/meloxicam ER) / Heron Therapeutics |
NCT06109428: A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE |
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| Completed | 4 | 30 | US | HTX-011, Bupivacaine Hydrochloride, Ibuprofen, Acetaminophen, Luer lock applicator | Heron Therapeutics | Analgesia | 03/22 | 04/22 | | |
NCT06109415: A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. |
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| Completed | 4 | 30 | US | HTX-011, Bupivacaine Hydrochloride, Ibuprofen, Acetaminophen, Luer lock applicator | Heron Therapeutics | Postoperative Pain, Total Shoulder Arthroplasty, Multimodal Analgesia | 07/22 | 07/22 | | |
NCT05188053: Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee Arthroplasty |
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| Enrolling by invitation | 4 | 98 | US | HTX-011, Zynrelef, ropivacaine , epinephrine , ketorolac diluted in sodium chloride, Mayo Clinic standard arthroplasty block | Mayo Clinic | Total Knee Arthroplasty | | | | |
NCT05109312: A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401. |
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| Active, not recruiting | 4 | 90 | US | Bupivacaine Hydrochloride, HTX-011, Luer lock applicator, Ibuprofen, Acetaminophen | Heron Therapeutics | Analgesia | 06/24 | 06/24 | | |
| Recruiting | 4 | 120 | US | ZYNRELEF 200Mg-6Mg Extended-Release Solution | Dr. Yannis Raftopoulos, Heron Therapeutics | Post Operative Pain, Acute, Bariatric Surgery Candidate, Postoperative Pain | 10/24 | 10/24 | | |
NCT05644496: ZYNRELEF for Pain Management in Total Knee Arthroplasty |
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| Recruiting | 4 | 242 | US | Bupivacaine-Meloxicam 400 Mg-12 Mg/14 mL Injectable Solution, Extended Release, Zynrelef | Baptist Health South Florida | Post Operative Pain, Osteoarthritis, Knee | 04/25 | 04/26 | | |
