Minnelide 101, NCT03129139: A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors |
|
|
| Recruiting | 1 | 66 | US | Minnelide™Capsules | Minneamrita Therapeutics LLC, Translational Drug Development | Advanced Cancer, Gastric Cancer, Breast Cancer, Pancreatic Cancer, Prostate Cancer Metastatic, Colo-rectal Cancer, Solid Tumor, Solid Carcinoma, Solid Carcinoma of Stomach, Cancer of Stomach | 06/24 | 12/24 | | |
| Recruiting | 1 | 30 | US | Biopsy, BIOPSY_TYPE, Bx, Osimertinib, AZD-9291, AZD9291, Mereletinib, Tagrisso, Triptolide Analog, Minnelide | City of Hope Medical Center, National Cancer Institute (NCI) | Advanced Lung Non-Small Cell Carcinoma, Locally Advanced Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8, Unresectable Lung Non-Small Cell Carcinoma | 10/26 | 10/26 | | |