Venclexta (venetoclax) / AbbVie, Roche, Walter and Eliza Hall Institute  >>  Phase 4
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42 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Venclexta (venetoclax) / Roche, AbbVie
ACTRN12624001142527: Safety analysis of 90-minute Obinutuzumab infusion

Not yet recruiting
4
128
 
Cairns Hospital , QLD health- Clinical research fellowship
Follicular lymphoma, Chronic Lymphocytic Leukaemia
 
 
ChiCTR1900026095: Venetoclax + azacitidine combined with dose-adjusted HAG double induction therapy for relapsed/refractory acute myeloid leukemia

Not yet recruiting
4
10
 
Venetoclax + Azacitidine +HAG
The People's Hospital of Jiaozuo City; The People's Hospital of Jiaozuo City, Beijing Medical Award Foundation
Relapse/Refractory Acute Myeloid Leukemia
 
 
2021-000722-96: changes in lymph nodes in patients with CLL treated with venetoclax-containing regimens Modificazioni del microambiente linfonodali in pazienti con leucemia linfatica cronica CLL in trattamento con regimi contenenti venetoclax

Not yet recruiting
4
30
Europe
Venclyxto, [Venclyxto], Coated tablet, venclyxto
OSPEDALE SAN RAFFAELE, AbbVie
Chronic Lymphocytic Leukemia Leucemia Linfatica Cronica, Chronic Lymphocytic Leukemia Leucemia Linfatica Cronica, Diseases [C] - Cancer [C04]
 
 
ChiCTR2100051018: The efficacy and safety of Venetoclax plus Azacitidine and LDAC in the treatment of relapsed and refractory acute myeloid leukaemia patients: Prospective, single arm, multicenter, phase 2 clinical study

Completed
4
31
 
VAA regimen
the First Affiliated Hospital of Zhejiang University School of Medicine; the First Affiliated Hospital of Zhejiang University School of Medicine, self-funded
Acute myeloid leukemia
 
 
ChiCTR2100054356: Clinical Efficacy of Low-Dose Venetoclax Combinated with Posaconazole in Acute Myeloid Leukemia Patients: Evaluation of Dose Adjustments Guided by Venetoclax Blood Concentration

Not yet recruiting
4
60
 
oral venetoclax 100mg/d combined with posaconazole200mg tid ;oral venetoclax 400mg/d
Chengdu Third People's Hospital; Chengdu Third People's Hospital, Personal research funds
acute myeloid leukemia
 
 
CCLG-AML 2019- Venetoclax targeted therapy, ChiCTR2200058925: China Children's Leukemia Group (CCLG) - AML2019 supplementary study on pediatric acute myeloid leukemia -Venetoclax therapy

Recruiting
4
50
 
venetocax ;venetocax ;venetocax ;venetocax
Beijing Children's Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, Capital Health Development Research Project (No. 2022-1-20191)
Acute myeloid leukemia (AML)
 
 
ChiCTR2200058721: Open-ended prospective clinical trial of skeleton scheme based on epigenetics in combination with DEL chemotherapy in relapsed/refractory children with acute T-lymphocyte leukemia (T-ALL) or T cell lymphoblastic lymphoma (T-NHL)

Not yet recruiting
4
60
 
Chidamide + HMAs + Venetoclax+Dex+VP16+Peg-Asp
Children's Hospital of Soochow University; Children's Hospital of Soochow University, Suzhou government and Children's Hospital of Soochow University
acute T-lymphocyte leukemia or T cell lymphoblastic lymphoma
 
 
ChiCTR2100048966: Venetoclax combined with HAG regimen in the treatment of adult refractory/relapsed ETP-ALL

Recruiting
4
53
 
Venetoclax+HAG solution
The First Affiliated Hospital, Zhejiang University College of Medicine; The First Affiliated Hospital, Zhejiang University College of Medicine, Self-raised
Early precursor T-cell acute lymphoblastic leukemia
 
 
ChiCTR2100050154: Clinical study of azacytidine combined with low-dose venetoclax in the treatment of untreated fragile senile AML

Not yet recruiting
4
30
 
Azacytidine plus low dose venetoclax
Beijing Hospital; Beijing Hospital, Raise independently
acute myeloid leukemia
 
 
ChiCTR2100050627: Clinical study of azacytidine combined with low-dose venetoclax in the treatment of relapse / refractory senile acute myeloid leukemia

Not yet recruiting
4
20
 
azacytidine plus low dose venetoclax
Beijing Hospital; Beijing Hospital, self-funded
acute myeloid leukemia
 
 
ChiCTR2200061294: A Prospective, Multicenter, Observational Clinical Study of the Pharmacokinetics and Pharmacodynamics of Venetoclax in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Not yet recruiting
4
 
The First Affiliated Hospital of Zhejiang University Medical College; The First Affiliated Hospital of Zhejiang University Medical College, Research funding
myelodysplastic syndromes, acute myeloid leukemia
 
 
ChiCTR2200057796: Individualized administration of Venetoclax based on PK/PD in children with refractory/relapsed acute leukemia

Recruiting
4
20
 
Venetoclax-based regimen
Beijing Children's Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, Capital Health and Development of Special Grant
pediatric acute leukemia
 
 
Venetoclax in APL reduction therapy, ChiCTR2300069288: China Children's Leukemia Group(CCLG) - APL 2021 supplementary study of

Recruiting
4
80
 
Venetoclax
Beijing Children's Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, self-raised
Acute promyelocytic leukemia (APL)
 
 
ChiCTR2200056993: Prospective, single-arm, multicenter clinical study of the efficacy and safety of venetoclax combined with azacitidine in the treatment of adult patients with higher-risk myelodysplastic syndrome

Recruiting
4
28
 
venetoclax + azacitidine
The First Affiliated Hospital of Zhejiang University Medical College; The First Affiliated Hospital, College of Medicine, Zhejiang University, Research funding
Myelodysplastic Syndrome
 
 
ChiCTR2100048811: Clinical trial of Venetoclax in combination with DA-EPOCH-R regimen for double/triple-hit high-grade B-cell lymphoma

Recruiting
4
48
 
Venetoclax combined with DA-EPOCH-R
The First Affiliated Hospital, Zhejiang University School of Medicine; The First Affiliated Hospital of Zhejiang University Medical college, Self-raised
Double-/Triple-Hit high-grade B-cell Lymphoma
 
 
TROPHY-AML03, NCT06571825: RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CR

Recruiting
4
118
RoW
Venetoclax, Allogeneic transplant
He Huang
Acute Myeloid Leukemia
12/27
02/28
NCT05144243: Study to Assess Adverse Events and Change in Disease State of Oral Venetoclax in Combination With Subcutaneous (SC) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Chemotherapy in China

Active, not recruiting
4
44
RoW
Venetoclax, ABT-199, GDC-0199, Venclexta, Azacitidine
AbbVie, Genentech, Inc.
Acute Myeloid Leukemia (AML)
03/26
03/26
NFEC-2024-639, NCT06763666: CLAG+VEN vs CLAG in the Treatment of Relapsed/Refractory AML

Not yet recruiting
4
172
RoW
Cladribine, 2-CdA, CdA, Cytarabine, Ara-C, G-CSF, Filgrastim, Granulocyte Colony-stimulating Factor, Venetoclax, Venclexta
Nanfang Hospital, Southern Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou No.12 People's Hospital, Guangzhou Panyu Central Hospital, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou First People's Hospital, Foresea Life Insurance Guangzhou General Hospital, Guangdong Second Provincial General Hospital, Jiangmen Central Hospital, Shantou Central Hospital, Maoming People's Hospital, First Affiliated Hospital of Guangxi Medical University, Hainan General Hospital, Dongguan People's Hospital, Tungwah Hospital of Sun Yat-Sen University, Shenzhen Hospital of Southern Medical University, Central People's Hospital of Zhanjiang, ZhuHai Hospital, Shenzhen Second People's Hospital, Zhongshan People's Hospital, Guangdong, China, LiuZhou People's Hospital, First People's Hospital of Foshan, Southern Medical University, China, Affiliated Hospital of Guangdong Medical University, Guilin Medical University, China, Yuebei People's Hospital, Huizhou Municipal Central Hospital, Second Affiliated Hospital of Guangzhou Medical University, Peking University Shenzhen Hospital
Relapsed/Refractory AML
06/25
12/25
NCT06651970: Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

Recruiting
4
60
Europe, US, RoW
Acalabrutinib, Calquence, Investigator's choice of treatment, Investigator's choice of treatment : i.e venetoclax, Rituximab, Obinutuzumab, Zanubrutinib etc.
AstraZeneca, Fortrea, CALYX Inc., eResearch Technology, Inc., CISCRP
Chronic Lymphocytic Leukaemia, Heart Failure
08/30
08/30
ChiCTR2400079363: A prospective, multicenter, single-arm clinical study of standard-dose Decitabine combined with Venetoclax for the treatment of myeloproliferative chronic myelomonocytic leukemia

Not yet recruiting
4
52
 
Standard-dose Decitabine (DEC) combined with Venetoclax (VEN)
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College; Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
myeloproliferative chronic myelomonocytic leukemia
 
 
ChiCTR2200058557: A prospective, multicentre, randomised, controlled study of Venetoclax and Azacitidine versus Azacitidine as maintenance therapy after allogeneic stem cell transplantation in patients with high risk of recurrence of MDS, CMML and AML

Recruiting
4
118
 
Venetoclax and Azacitidine Combination ;Azacitidine
Blood Diseases Hospital, Institute of Hematology, Chinese Academy of Medical Sciences; Blood Diseases Hospital, Institute of Hematology, Chinese Academy of Medical Sciences, None
Myelodysplastic syndrome (MDS)/chronic monocytic leukemia (CMML)/acute myeloid leukemia (AML)
 
 
ChiCTR2200061423: The validity and safety of Venetoclax combined with Azaciticidine for the treatment of de novo higher-risk chronic myelomonocytic leukemia: A prospective, single-arm, multicenter study

Not yet recruiting
4
48
 
venetoclax combined with azacytidine
The First Affiliated Hospital of Zhejiang University; Zhejiang Provincial Hospital of Chinese Medicine, None
Chronic myelomonocytic leukemia
 
 
ChiCTR2400084836: A cohort study of azacitidine combined with different dosages of venetoclax in the treatment of elderly patients with AML unsuitable for chemotherapy

Not yet recruiting
4
320
 
None; None
Beijing Hospital; Beijing Hospital, Beijing Hospital Clinical Research "Navigation Aid" Special Project
AML
 
 
NCT07044687: Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India

Recruiting
4
100
RoW
Venetoclax, Azacitidine
AbbVie
Acute Myeloid Leukemia
11/27
11/27
Relapsed pediatric APL protocol, ChiCTR2400082058: A multicenter study of relapsed pediatric acute promyelocytic leukemia protocol

Not yet recruiting
4
20
 
Venetoclax-based treatment protocol
Beijing Children's Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, self-raised
Acute promyelocytic leukemia in children and adolescents
 
 
ChiCTR2300078643: Efficacy and safety of IVPD regimen in patients with relapsed/refractory multiple myeloma resistant to bortezomib and/or lenalidomide: a multicenter, single-arm, prospective clinical study

Recruiting
4
67
 
Ixazomib; Venetoclax; Pomalidomide; Dexamethasone
The Second Hospital of Hebei Medical University; The Second Hospital of Hebei Medical University, None
multiple myeloma
 
 
ChiCTR2300069327: Prospective, Multicenter, Single-Arm Clinical Study of Venetoclax Combined with Cladribine + HAG Regimen in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia

Not yet recruiting
4
106
 
Venetoclax Combined With Cladribine + HAG
The First Affiliated Hospital of Army Medical University (Southwest Hospital); The First Affiliated Hospital of Army Medical University (Southwest Hospital), NA
Relapsed/refractory acute myeloid leukemia
 
 
ChiCTR2200061524: Clinical study of venetoclax combined with chemotherapy in the treatment of newly diagnosed acute myeloid leukemia

Recruiting
4
60
 
Oral venetoclax ;Without venetoclax
Handan Central Hospital; Handan Central Hospital, Self-paying
Acute myeloid leukemia
 
 
LymBIO, NCT04790045: Lymph Node Microenvironment Modifications in Patients With CLL Treated With Venetoclax-based Regimens

Not yet recruiting
4
30
NA
Venetoclax, core-needle biopsy
Paolo Ghia
Chronic Lymphocytic Leukemia
12/26
12/26
ChiCTR2400080307: Multicenter clinical study of CCLG-AML2024 protocol (except APL)

Not yet recruiting
4
816
 
The combination of targeted therapy and chemotherapy was applied in the treatment of reduction of volume, induction therapy, consolidation therapy and maintenance therapy, and venetoclax combined with RIF in maintenance period; The combination of targeted therapy and chemotherapy was applied in the treatment of reduction of volume, induction therapy, consolidation therapy and maintenance therapy, and only Venetoclax in maintenance period
Beijing Children's Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, self-raised
Acute myeloid leukemia in children
 
 
CCLG-APL 2024 protocol, ChiCTR2400085721: A multi-centre clinical study of the

Not yet recruiting
4
200
 
Targeted therapy with retinoic acid and arsenic in combination with venetoclax
Beijing Children's Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, self-raised
Acute promyelocytic leukemia in children and adolescents
 
 
ChiCTR2400086528: A prospective, single-center, exploratory study of mitoxantrone hydrochloride liposome injection combined with standard-dose cytarabine and venetoclax in the treatment of relapsed/refractory acute myeloid leukemia

Not yet recruiting
4
20
 
Mitoxantrone hydrochloride liposome+standard-dose cytarabine+venetoclax
The First Affiliated Hospital, College of Medicine, Zhejiang University; The First Affiliated Hospital, College of Medicine, Zhejiang University, CSPC OUYI PHARMACEUTICAL CO., LTD.
Relapsed/Refractory Acute Myeloid Leukemia
 
 
ChiCTR2400083301: A prospective multicenter cohort study of Venetoclax combined with DCAG regimen for the treatment of newly diagnosed high-risk acute myeloid leukemia

Not yet recruiting
4
38
 
Inducing by Venetolcax+DCAG regimen
Peking University People's Hospital; Peking University People's Hospital, People's Hospital, Institute of Hematology, Peking University
Hiigh-risk acute myeloid leukemia
 
 
ChiCTR2400086497: Efficacy and safety of all-trans retinoic acid, decitabine combined with venetoclax for maintenance in non-transplant patients with acute myeloid leukemia

Not yet recruiting
4
60
 
all-trans retinoic acid, decitabine and venetoclax; none
The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University; The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Anti-Cancer Association Clinical Research (HENGRUI) Funding General Project of Sichuan Province (XH2023 3012)
acute myeloid leukemia
 
 
ChiCTR2500109729: A multicenter, single-arm, phase II clinical study of mitoxantrone hydrochloride liposome injection combined with azacitidine and venetoclax in the treatment of relapsed/refractory acute myeloid leukemia after standard induction therapy

Not yet recruiting
4
38
 
Mitoxantrone hydrochloride liposome injection combined with azacitidine and venetoclax (MAV)
The First Affiliated Hospital of Army Medical University; The First Affiliated Hospital of Army Medical University, Subject of your choice (self-supporting)
Acute myeloid leukemia
 
 
ChiCTR2500109360: A multicenter, single-arm, phase II clinical study of mitoxantrone hydrochloride liposome injection combined with azacitidine and venetoclax in the treatment of venetoclax-exposed refractory/relapsed acute myeloid leukemia

Not yet recruiting
4
30
 
Mitoxantrone hydrochloride liposome injection combined with azacitidine and venetoclax (MAV)
The First Affiliated Hospital of Army Medical University; The First Affiliated Hospital of Army Medical University, Subject of your choice (self-supporting)
Acute myeloid leukemia
 
 
ChiCTR2400090947: Venetoclax combined with medium-dose cytarabine as consolidation therapy after standard induction chemotherapy in patients with Fit AML: a multicenter, prospective, observational clinical study

Not yet recruiting
4
180
 
Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, Self-financing
AML
 
 
ChiCTR2400087347: Clinical Study Protocol for Venetoclax and Azacitidine for the Maintenance Treatment of Post-Remission AML

Recruiting
4
114
 
Venetoclax in combination with azacitidine for the maintenance treatment of post-remission AML
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Self-financing
Acute myeloid leukemia (AML)
 
 
ChiCTR2500111194: Study on the Efficacy and Safety of Mitoxantrone Liposome-Containing Regimens in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia in the Real World

Recruiting
4
60
 
Mitoxantrone hydrochloride liposome+Azacitidine+Venetoclax
Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology; Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology, Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology
Acute myeloid leukemia
 
 
ChiCTR2400091259: A prospective, single-center, single-arm study of mitoxantrone hydrochloride liposome injection combined with venetoclax and azacitidine in the treatment of newly diagnosed and relapsed/refractory acute myeloid leukemia

Not yet recruiting
4
40
 
mitoxantrone hydrochloride liposome+venetoclax+azacitidine
General Hospital of Chinese People's Liberation Army Northern Theater Command; General Hospital of Chinese People's Liberation Army Northern Theater Command, self-financed
Acute Myeloid Leukemia
 
 
ChiCTR2500109764: A Prospective, Multicenter, Randomized Controlled, Phase II Clinical Study of Venetoclax and Azacitidine Combined with Mitoxantrone Hydrochloride Liposome Injection Versus Intensive Chemotherapy in the Treatment of Newly Diagnosed Intermediate- to High-Risk fit AML

Not yet recruiting
4
198
 
VMA therapy; Intensive therapy (IA or DA)
Tangdu Hospital, Fourth Military Medical University; Tangdu Hospital, Fourth Military Medical University, Shiyao Group Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Acute myeloid leukemia
 
 
ChiCTR2400084237: A prospective, multi-center, randomized controlled clinical study of mitoxantrone liposome-based three-drug combination regimen for the treatment of relapsed and refractory acute myeloid leukemia

Not yet recruiting
4
100
 
Liposomal mitoxantrone combined with venetoclax and azacitidine; venetoclax combined with azacitidine.
Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology; Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology, Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology
acute myeloid leukemia
 
 

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