| venlafaxine / Generic mfg. |
ChiCTR-ROC-17010393: Efficacy research of acupuncture combined with venlafaxine in treating depression based on DTI |
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| Recruiting | N/A | 60 | | Nil | tongde hospital of zhejiang province; tongde hospital of zhejiang province, Science Technology Department of Zhejiang Province | Depression | | | | |
| Completed | N/A | 300 | Europe | venlafaxine | Radboud University Medical Center | Dyspepsia | | 07/07 | | |
NCT00159146: Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression |
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| Terminated | N/A | 31 | Europe | Pindolol and venlafaxin | Hillerod Hospital, Denmark, Wyeth is now a wholly owned subsidiary of Pfizer, Tvergaards Foundation | Major Depression | | 09/07 | | |
NCT00084669: Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer |
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| Completed | N/A | 119 | US | venlafaxine, zolpidem tartrate, management of therapy complications | Massachusetts General Hospital | Breast Cancer, Hot Flashes, Sleep Disorders | 10/07 | 03/10 | | |
NCT00763724: Antidepressant Drug Exposure and Risk of Suicide Attempt Resulting in Medical Intervention in US Adults |
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| Completed | N/A | 254432 | US | | Eli Lilly and Company | Depression, Suicide | 11/09 | 11/09 | | |
| Completed | N/A | 364 | Europe | | AstraZeneca | Major Depressive Disorder | | 11/09 | | |
NCT00944996: Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression |
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| Completed | N/A | 100 | RoW | SSRI; SNRI; TCA, paroxetine, fluoxetine, sertraline, escitalopram, citalopram, mirtrazapine, venlafaxine, anafranil | Tirat Carmel Mental Health Center, University of Michigan, Ariel University, The Nazareth Hospital, Israel | Major Depression | 06/10 | 07/12 | | |
| Unknown status | N/A | 150 | Canada | Venlafaxine, Effexor, bupropion, Wellbutrin, escitalopram, Cipralex, Psychotherapy, CBT, Duloxetine, Cymbalta | St. Joseph's Healthcare Hamilton | Major Depressive Disorder | 10/12 | 10/13 | | |
NCT01000623: Venlafaxine and Hypnosis or Focused Attention In Treating Patients With Hot Flashes |
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| Withdrawn | N/A | 0 | US | venlafaxine, Effexor, VNF, placebo, PLCB, hypnotherapy, hypnosis, mind-body intervention procedure, mind-body interventions | Mayo Clinic, National Cancer Institute (NCI) | Hot Flashes | 11/12 | 09/15 | | |
NCT01488266: Aripiprazole Augmentation Versus Switching to Different Class of Antidepressants in Major Depressive Disorder |
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| Unknown status | N/A | 90 | RoW | Aripiprazole, abilify, switching to different class of antidepressant, escitalopram, fluoxetine, paroxetine, sertraline, bupropion XL, mirtazapine, venlafaxine, milnacipran, duloxetine | Korea University, Korea OIAA, Taiwan Otsuka Pharm. Co., Ltd | Major Depressive Disorder | 01/13 | 03/13 | | |
NCT02012504: Antidepressant Monotherapy on Depressive and Anxiety Symptom in Chinese Patients |
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| Unknown status | N/A | 50 | RoW | | Shanghai Zhongshan Hospital | Adverse Drug Reaction, Anxiety Disorders and Symptoms | 01/14 | 12/14 | | |
NCT01611155: Venlafaxine in Preventing Chronic Oxaliplatin-Induced Neuropathy In Patients Receiving Combination Chemotherapy |
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| Completed | N/A | 50 | US | venlafaxine, Effexor, VNF, placebo, PLCB, questionnaire administration, quality-of-life assessment, quality of life assessment | Mayo Clinic | Peripheral Neuropathy | 03/14 | 09/15 | | |
NCT00667121: Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline |
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| Active, not recruiting | N/A | 85 | US | citalopram hydrobromide, escitalopram oxalate, gabapentin, sertraline hydrochloride, tamoxifen citrate, venlafaxine, molecular genetic technique, high performance liquid chromatography, laboratory biomarker analysis, pharmacological study, adjuvant therapy | Mayo Clinic, National Cancer Institute (NCI) | Breast Cancer, Depression, Hot Flashes, Psychosocial Effects of Cancer and Its Treatment | 05/14 | 12/24 | | |
ChiCTR-OCH-13003864: Herbal medicine for hospitalized patients with severe depressive episode: a retrospective controlled study. |
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| Completed | N/A | 140 | | the herbal preparation Gui-Pi Decoction combined venlafaxine ;venlafaxine only | Tongde Hospital of Zhejiang Province; Tongde Hospital of Zhejiang Province, First-phase Research Fund for Young Medical Investigators of Zhejiang Province | Major depressive disorder (MDD) | | | | |
NCT01896349: Interpersonal Psychotherapy for Treatment Resistant Depression |
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| Unknown status | N/A | 74 | RoW | IPT+ antidepressant drugs, Interpersonal Psychotherapy, Antidepressant drugs, fluoxetine, sertraline, paroxetine, Citalopram, escitalopram, fluvoxamine, Venlafaxine, Duloxetine, Bupropion, Lithium, Risperidone, tranylcypromine, Imipramine, amitriptyline, Clomipramine, nortriptyline, trazodone, Mirtazapine, sulpiride | Hospital de Clinicas de Porto Alegre | Treatment Resistant Depression | 08/14 | 11/14 | | |
ChiCTR-OCH-13003718: Study of the effects of venlafaxine for the brain plasticity of patients with generalized anxiety disorder |
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| Completed | N/A | 60 | | Venlafaxine Hydrochloride SR Capsule ;None | Shanghai Mental Health Center; None, Pfizer Investigator Initiated Research | generalized anxiety disorder | | | | |
| Completed | N/A | 3255526 | Canada | Duloxetine, Venlafaxine, Desvenlafaxine, Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline | Canadian Network for Observational Drug Effect Studies, CNODES, Drug Safety and Effectiveness Network, Canada, Canadian Institutes of Health Research (CIHR) | Depression, Acute Kidney Injury | 12/14 | 12/14 | | |
NCT02476136: Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis |
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| Unknown status | N/A | 8800 | NA | paroxetine, duloxetine, fluoxetine or venlafaxine, Paxil, Cymbalta, Prozac, Effexor | prof. Peter de Jonge | Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder | 03/16 | 12/16 | | |
PG, NCT00817011: Development of Pharmacogenomic Method to Predict Antidepressant Responsiveness |
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| Unknown status | N/A | 1000 | RoW | SSRI treated group, Other Names:, fluoxetine_Prozac, paroxetine_Paxil, Seroxat, sertraline_Zoloft, citalopram_Celexa, non-SSRI treated group, venlafaxine_Effexor, nortriptyline_Aventyl, Pamelor, Noritren, mirtazapine_Avanza, Zispin, Remeron, bupropion_amfebutamone, Wellbutrin, Zyban, duloxetine_Cymbalta, Yentreve, trazodone_Desyrel, Beneficat, Deprax | Samsung Medical Center | Depression, Antidepressant Drug Adverse Reaction | 12/16 | 03/18 | | |
| Completed | N/A | 5 | US | Placebo, Venlafaxine | Johns Hopkins University | Alzheimer's Disease, Depression | 12/16 | 01/17 | | |
NCT01516931: Efficacy of Repetitive Transcranial Magnetic Stimulation in the Prevention of Relapse of Depression |
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| Completed | N/A | 391 | RoW | repetitive Transcranial Magnetic Stimulation (rTMS), counseling | Xijing Hospital, The No.3 hospital of PLA, The No.91 hospital of PLA, No. 102 Hospital of Chinese People's Liberation Army | Depression | 12/16 | 02/17 | | |
NCT02934035: Early Improvement in Individual Symptoms and Response to Antidepressants in Patients With Major Depressive Disorder |
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| Unknown status | N/A | 10000 | NA | Antidepressant, Duloxetine, Paroxetine, Escitalopram, Fluoxetine, Venlafaxine | University Medical Center Groningen | Major Depressive Disorder | 09/17 | 09/17 | | |
ChiCTR-INR-16008971: Efficacy and safety of ketamine combined with antidepressants in major depression: a randomized controlled trial |
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| Not yet recruiting | N/A | 40 | | single-dose i.v. ketamine (0.5mg/kg, 40 minutes)+ venlafaxine (150 mg/day, 4weeks) ;single-dose i.v. midazolam (0.045 mg/kg, 40 minutes) + venlafaxine (150 mg/day, 4weeks) | Beijing Chaoyang Hospital; Beijing Chaoyang Hospital, Beijing Key Laboratory for mental disorders | depression disorder | | | | |
NCT03126188: Study of the Effect of Antidepressant Drugs on Neurotrophic Factors in Patients With Depression |
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| Completed | N/A | 105 | RoW | Sertraline, Dosulepin, Venlafaxine | All India Institute of Medical Sciences, Bhubaneswar | Depressive Episode | 12/17 | 02/18 | | |
NCT02441387: Predictors of the Outcome of Late Life Depression |
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| Unknown status | N/A | 120 | RoW | Antidepressant, zoloft, lexapro, efexor, remeron, carbolithium, Psychoeducation, Treatment as usual (only pharmacological treatment). | University of Sao Paulo General Hospital, Fundação de Amparo à Pesquisa do Estado de São Paulo | Major Depression | 03/18 | 07/19 | | |
| Completed | N/A | 104 | NA | Sertraline or venlafaxine, Immune parameters | Kliniken Essen-Mitte, University of Bordeaux, IRCCS Centro San Giovanni di Dio Fatebenefratelli, Ruhr University of Bochum, National Research Agency, France, Créteil Hospital, German Federal Ministry of Education and Research, Ministry of Health, Italy | Depressive Disorder, Depression, Inflammation | 03/18 | 03/18 | | |
NCT01352572: Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients |
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| Unknown status | N/A | 300 | RoW | antidepressant response, fluoxetine_Prozac, paroxetine_Paxil, Seroxat, sertraline_Zoloft, milnacipran, venlafaxine_Effexor, nortriptyline_Aventyl, Pamelor, Noritren, mirtazapine_Avanza, Zispin, Remeron, antidepressant non-response, fluoxetine, paroxetine, sertraline, milnacipran, venlafaxine, nortriptyline, mirtazapine | Samsung Medical Center | Depression | 12/18 | 12/18 | | |
NCT01228357: Predict Antidepressant Responsiveness Using Pharmacogenomics |
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| Unknown status | N/A | 1000 | RoW | SSRI treated group, fluoxetine_Prozac, paroxetine_Paxil, Seroxat, sertraline_Zoloft, non-SSRI treated group, milnacipran, venlafaxine_Effexor, nortriptyline_Aventyl, Pamelor, Noritren, mirtazapine_Avanza, Zispin, Remeron | Samsung Medical Center | Depression, Depressive Symptoms | 12/18 | 12/18 | | |
NCT00817375: Pharmacogenomic Study to Predict Antidepressant Responsiveness in Depressed Patients |
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| Unknown status | N/A | 1000 | RoW | SSRI treated group, fluoxetine_Prozac, paroxetine_Paxil, Seroxat, sertraline_Zoloft, non-SSRI treated group, milnacipran, venlafaxine_Effexor, nortriptyline_Aventyl, Pamelor, Noritren, mirtazapine_Avanza, Zispin, Remeron | Samsung Medical Center | Depression, Adverse Reaction to Drug | 12/18 | 12/18 | | |
INGenious, NCT02297126: A Prospective Trial to Assess Cost and Clinical Outcomes of a Clinical Pharmacogenomic Program |
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| Completed | N/A | 4465 | US | Pharmacogenetic Intervention Arm (pharmacogenetic testing) | Indiana University, National Human Genome Research Institute (NHGRI) | Adverse Drug Reaction | 05/19 | 05/19 | | |
ChiCTR-IOR-17012419: A Clinical Study Program about Treatment of Migraine - Depression Syndrome by Jieyu Decoction |
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| Recruiting | N/A | 100 | | Oral Jieyu therapy ;Venlafaxine capsules | Shanghai TCM-integrated Hospital; Shanghai TCM-integrated Hospital, Shanghai science and Technology Committee | Migraine - Depression Syndrome | | | | |
| Terminated | N/A | 68 | Canada | No intervention | The Hospital for Sick Children | Lactation | 09/19 | 09/19 | | |
TSOS6, NCT02655354: A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity |
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| Completed | N/A | 635 | US | Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Citalopram, Venlafaxine, Duloxetine, Mirtazapine, Diphenhydramine, Trazodone, Prazosin | University of Washington, National Institutes of Health (NIH), National Institute of Mental Health (NIMH), National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation, Substance-Related Disorders, Mild Cognitive Impairment, Quality of Life, Pain, Wounds and Injury, Brain Injuries, Chronic Disease | 11/19 | 11/19 | | |
| Unknown status | N/A | 205 | Europe | cocktail probe drugs | Assistance Publique - Hôpitaux de Paris | Major Depressive Disorders | 12/19 | 04/20 | | |
ChiCTR1900026704: The role of miR-34b/c dysregulation and clinical transformation in depression |
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| Recruiting | N/A | 120 | | N/A ;venlafaxine treatment for depression group | Shanxi Medical University; The First Clinical Hospital of Shanxi Medical University, Youth Science Fund project | Mood Disorders, psychological and physiological disorders and psychosomatic diseases | | | | |
ChiCTR1900028259: Comparative study for the effects of venlafaxine and duloxetine in the treatment of chemotherapy-induced peripheral neuropathy |
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| Not yet recruiting | N/A | 120 | | CIPN is treated with venlafaxine or duloxetine ;CIPN is treated with venlafaxine or duloxetine | The Second Affiliated Hospital of Fujian Medical University; The Second Affiliated Hospital of Fujian Medical University, Scientific research fund of the Second Affiliated Hospital of Fujian Medical University | cancer | | | | |
NCT02873234: A Study of Chinese Medicine Treating Depression |
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| Unknown status | N/A | 4600 | RoW | Traditional Chinese Medicine, Chinese Medicine, Chinese Herb Medicine, Antidepressants | The Third Affiliated Hospital of Beijing University of Chinese Medicine, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing HuiLongGuan Hospital, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, First Affiliated Hospital of Heilongjiang Chinese Medicine University, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Capital Medical University, Xiamen Hospital of Traditional Chinese Medicine, Wu Xi Hospital of Traditional Chinese Medicine | Depression | 05/20 | 05/20 | | |
NCT02958527: Drug Use Investigation Of Effexor (SECONDARY DATA COLLECTION STUDY; SAFETY AND EFFICACY OF EFFEXOR.UNDER JAPANESE MEDICAL PRACTICE) |
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| Completed | N/A | 1408 | NA | venlafaxine, Effexor | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Depression/Depressed State | 05/20 | 05/20 | | |
NCT02955719: CAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In Dementia |
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| Completed | N/A | 145 | Canada | Sertraline, zoloft, Venlafaxine, effexor, CBT/Psychological Therapy, Psychiatric Consultation, Lifestyle Intervention Resources | Centre for Addiction and Mental Health, McMaster University | Depression, Anxiety, Mild Cognitive Impairment | 07/20 | 07/20 | | |
ChiCTR1800017626: A precision medicine study on the treatment of depression using Venlafaxine and Escitalopram |
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| Recruiting | N/A | 4200 | | oral administration of Venlafaxine (75-225 mg/day) ;oral administration of Escitalopram (10-20 mg/day) | Zhejiang University; The First Affliated Hospital, Zhejiang University School of Medicine, National Key Research and Development Plan, Precision Medicine Research Key Special Project | Depression | | | | |
ChiCTR1800017848: Single i.v.-ketamine augmentation of newly initiated venlafaxine hydrochloride for treatment-resistant depression: a randomized controlled trial |
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| Recruiting | N/A | 40 | | single-dose i.v. ketamine (0.5mg/kg, 40 minutes)+ venlafaxine (4 weeks, 75mg/day in the first week and 150mg/day in the other 3 weeks) ;single-dose i.v. midazolam (0.045mg/kg, 40 minutes)+ venlafaxine (4 weeks, 75mg/day in the first week and 150mg/day in the other 3 weeks) | Beijing Chaoyang Hospital; Beijing Chaoyang Hospital, Capital's Funds for Health Improvement and Research(CFH) | depression disorder | | | | |
ChiCTR2100049812: The effects of Zuojin Pill on the pharmacokinetics of venlafaxine in healthy volunteers |
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| Completed | N/A | 308 | | Single dose of venlafaxine ;concomitant use of venlafaxine and zuojin pill | Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine; Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai Municipal Health Committee | NA | | | | |
NCT03294525: Towards Neurobiology-based Diagnosis and Treatment of Affective Disorders |
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| Recruiting | N/A | 400 | RoW | Escitalopram Pill, Lexapro, Duloxetine, Cymbalta, Mirtazapine Pill, Remeron, Other Antidepressants | Peking University | Affective Disorder | 12/21 | 08/22 | | |
BATEP, NCT04396314: Effectiveness of Basic Body Awareness Therapy in Post-traumatic Stress Disorders: A Randomized Clinical Trial |
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| Not yet recruiting | N/A | 54 | NA | Basic Body Awareness Therapy, Psychological treatment | Universitat de Lleida, Francesc Rubí Carnacea | PostTraumatic Stress Disorder | 12/21 | 04/22 | | |
ChiCTR2000040228: Analysis of the effect of exercise-assisted therapy on improving mood disorders |
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| Not yet recruiting | N/A | 200 | | Sports +Venlafaxine Hydrochloride + Oxazepam ;Venlafaxine Hydrochloride + Oxazepam | Tongji Medical College Huazhong University of Science and Technology; Tongji Medical College Huazhong University of Science and Technology, Huawei Terminal Co., Ltd. | depression | | | | |
CAR-BIG, NCT04446039: Non-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in Korea |
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| Completed | N/A | 405349 | RoW | Escitalopram, Paroxetine, Fluoxetine, Mirtazapine, Duloxetine, Sertraline, Venlafaxine, Tianeptine, Vortioxetine, Desvenlafaxine, Bupropion | Pfizer | Major Depression | 11/22 | 11/22 | | |
| Recruiting | N/A | 1000 | | Antidepressants (sertraline, esitalopram, venlafaxine) ;None | Fudan University; The Second Xiangya Hospital of Central South University, Shanghai Municipal Science and Technology Major Project | Major depressive disorder | | | | |
NCT04664088: Acupuncture for Prophylaxis of Vestibular Migraine |
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| Not yet recruiting | N/A | 72 | RoW | Acupuncture, Venlafaxine | First Affiliated Hospital of Jiaxing University | Vestibular Migraine | 06/23 | 12/23 | | |
NCT05952713: Comparative Responses to 15 Different Antidepressants in Major Depressive Disorder |
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| Completed | N/A | 73336 | Europe | Antidepressant, sertraline, citalopram, fluoxetine, paroxetine, escitalopram, reboxetine, venlafaxine, duloxetine, mirtazapine, vortioxetine, agomelatine, amitriptyline, imipramine | Mental Health Services in the Capital Region, Denmark, University of Copenhagen | Major Depressive Disorder | 07/23 | 07/23 | | |
NCT05931965: Combination Therapy of Different Antidepressants With Dietary Supplements |
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| Completed | N/A | 88 | RoW | L-methylfolate, 5-methyl-terahydrofolate, Vitamin B12, mecobalamin, magnesium, Mg | Riphah International University | Depression | 07/23 | 08/23 | | |
| Recruiting | N/A | 1000 | | Antidepressants (fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, esitalopram, venlafaxine) ;None | West China Hospital, Sichuan University ; West China Hospital of Sichuan University, National Natural Science Foundation of China | depression | | | | |
NCT03511118: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants |
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| Recruiting | N/A | 1600 | Canada, US | Tranexamic acid (TXA), labetalol, metformin, nifedipine, clindamycin, oxycodone, azithromycin, escitalopram, sertraline, ondansetron, Ciprofloxacin, Doxycycline, Levofloxacin, Methylphenidate, Sumatriptan, Citalopram, Cyclobenzaprine, Furosemide, Gabapentin, Hydrochlorothiazide, Hydroxyurea, Rosuvastatin, Topiramate, Trazodone, Valganciclovir, Venlafaxine, Verapamil, Remdesivir, Anakinra, Tocilizumab, Fluvoxamine, Amoxicillin, Bupropion, Duloxetine, Hydrocodone, Levetiracetam, Paroxetine, Buprenorphine | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI | 09/24 | 09/24 | | |
NCT05830279: Implementation of Personalized Medicine for Optimal Drug Therapy in Cancer |
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| Recruiting | N/A | 600 | Canada | Pharmacogenetic testing, Drug-Drug interaction analysis | Lawson Health Research Institute | Nausea With Vomiting Chemotherapy-Induced, Depression, Reactive, Cancer Pain | 04/25 | 04/25 | | |
OPTION-VMS, NCT06049797: A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats |
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| Recruiting | N/A | 1000 | US | Fezolinetant, ESN364, VEOZAH, Paroxetine, Citalopram, Escitalopram, Desvenlafaxine, Venlafaxine, Gabapentin, Clonidine, Pregabalin, Oxybutynin, Any other SSRI/SNRI not already specified, Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above | Astellas Pharma Global Development, Inc. | Hot Flashes | 09/25 | 09/25 | | |
NCT05777876: Early Identification of TRD and Construction and Clinical Validation of NTBS Precision Technology |
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| Recruiting | N/A | 400 | RoW | non-invasive transcranial deep brain stimulation, Sham stimulation, Motor cortex stimulation, non-invasive transcranial deep brain stimulation with closed-loop | First Affiliated Hospital of Zhejiang University, Zhejiang University, Kangci Hospital of Jiaxing, Wenzhou Seventh People's Hospital, Lishui Second People's Hospital, Huzhou Third People's Hospital, Binjiang Institute of Zhejiang University, Zhejiang Newways Medical Technology Co., Ltd, Hangzhou Lingnao Technology Co., Ltd | Treatment-Resistant Depression | 12/25 | 12/25 | | |
