| venlafaxine / Generic mfg. |
NCT00792168: Physiologic Monitoring of Antidepressant Treatment Response |
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| Completed | 4 | 38 | US | venlafaxine (Effexor), placebo | University of California, Los Angeles | Major Depression | | 12/98 | | |
| Completed | 4 | 37 | US | venlafaxine (Effexor) | University of California, Los Angeles, Wyeth is now a wholly owned subsidiary of Pfizer | Depression | 08/02 | 09/02 | | |
NCT00177567: Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study |
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| Completed | 4 | 60 | US | lithium carbonate, Depakote-ER, risperidone, olanzapine, paroxetine, bupropion, lamotrigine, venlafaxine, tranylcypromine, mirtazapine | University of Pittsburgh | Bipolar Disorder | | 01/04 | | |
NCT00546494: Study Evaluating Effexor® (Venlafaxine) in Achieving Response and Maintaining Remission |
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| Completed | 4 | 350 | RoW | Effexor® (Venlafaxine) | Wyeth is now a wholly owned subsidiary of Pfizer | Depression | | 03/05 | | |
NCT00759122: Electroencephalography (EEG) Biomarkers of Response in Depression |
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| Completed | 4 | 44 | US | venlafaxine (Effexor), placebo | University of California, Los Angeles, Medtronic - MITG, Wyeth is now a wholly owned subsidiary of Pfizer | Major Depressive Disorder | 11/05 | 12/05 | | |
NCT00157547: Quantitative EEG (QEEG) as a Predictor of Treatment Outcome in Depression |
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| Completed | 4 | 95 | US | Selective serotonin reuptake inhibitors (SSRI), fluoxetine, sertraline, paroxetine, fluvoxamine, citalopram, escitalopram, venlafaxine | Massachusetts General Hospital, Medtronic - MITG | Major Depressive Disorder | 08/06 | 08/06 | | |
NCT00045916: Optimizing Electroconvulsive Therapy for Depression |
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| Completed | 4 | 340 | US | High dosage electroconvulsive therapy, Nortriptyline, Venlafaxine, Lithium, Low dosage electroconvulsive therapy | New York State Psychiatric Institute, National Institute of Mental Health (NIMH) | Depression, Depressive Disorder, Bipolar Disorder | 12/06 | 12/06 | | |
NCT00611676: A Single-Blind Placebo Run-In Study of Venlafaxine for Activity-Limiting Osteoarthritis Pain |
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| Completed | 4 | 18 | US | Venlafaxine | University of Washington, Wyeth is now a wholly owned subsidiary of Pfizer | Osteoarthritis, Pain | 02/07 | 02/07 | | |
| Completed | 4 | 491 | US | Brief Supportive Psychotherapy, CBASP, Cognitive Behavioral Analysis System of Psychotherapy, Medication Only, one of five antidepressants | Weill Medical College of Cornell University, National Institute of Mental Health (NIMH) | Depression, Depressive Disorder | 03/07 | 03/07 | | |
NCT00205491: Pharmacological Intervention in Depression After Traumatic Brain Injury |
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| Completed | 4 | 100 | US | Venlafaxine | Virginia Commonwealth University, U.S. Department of Education | TBI (Traumatic Brain Injury) | 09/07 | 09/07 | | |
NCT00634283: Study of the Effects of an Antidepressant Medication and Placebo on the Brain Functioning of Normal Subjects |
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| Completed | 4 | 6 | US | venlafaxine, Effexor | University of California, Los Angeles | Depression | 02/09 | 02/09 | | |
| Unknown status | 4 | 200 | RoW | Venlafaxine, Fluoxetine | National Cheng-Kung University Hospital, Department of Health, Executive Yuan, R.O.C. (Taiwan) | Major Depressive Disorder, Antidepressive Agents, Pharmacogenetics, Venlafaxine, Fluoxetine | 12/10 | 02/11 | | |
ChiCTR-TNRC-10001112: The study on clinical and biological characters of bipolar depression and the treatment scheme optimizing |
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| Completed | 4 | 640 | | Lithium, Sodium valproate, Lamotrigine, MECT, Sertraline, Citalopram, Escitalopram, venlafaxine, Quetiapine, Olanzapine, Risperidone, sulpiride | Guangzhou Scientific and Technological Bureau, Guangzhou Board of Health; Guangzhou first people's hospital, The Tackling Key Problems of Guangzhou Scientific and Technological Project | bipolar depressive disorder | | | | |
ACTRN12613000256774: Escitalopram efficacy and tolerability in treatment resistant depression. an open study. |
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| Completed | 4 | 417 | | | Lundbeck , Lundbeck | Major Depression | | | | |
NCT01443520 / 2011-003259-20: Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers |
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| Completed | 4 | 12 | Europe | Placebo, Duloxetine, Venlafaxine | Turku University Hospital | Healthy | 01/12 | 01/12 | | |
NCT00627887: Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of Depression |
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| Completed | 4 | 56 | Europe | Electroconvulsive therapy, ECT, venlafaxine, Efexor, Effexor, Lithium, Lithionit, Lithobid, Eskalith | Örebro County Council, Uppsala-Örebro Regional Research Council | Depressive Disorder, Major | 05/12 | 05/12 | | |
NCT00602537: Antidepressant Therapy in Treating Bipolar Type II Major Depression |
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| Completed | 4 | 140 | US | Venlafaxine, Lithium Carbonate | University of Pennsylvania, National Institute of Mental Health (NIMH) | Bipolar Disorder, Depression | 06/13 | 06/13 | | |
NCT01436643 / 2011-001692-39: Combination of Antidepressants and Fingolimod Relapsing-remitting Multiple Sclerosis (RRMS) Patients With Depression |
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| Terminated | 4 | 54 | Europe | Venlafaxine, Fluoxetine, Citalopram, Fingolimod | Novartis Pharmaceuticals | Depression, Relapsing-remitting Multiple Sclerosis | 09/13 | 09/13 | | |
| Completed | 4 | 889 | Europe | Escitalopram, venlafaxine, lithium, Escitalopram, venlafaxine | K. Lieb, German Federal Ministry of Education and Research | Depression | 05/14 | 05/14 | | |
| Terminated | 4 | 104 | Europe | C-ECT, Thrymatron System IV device (Somatics, LLC, ISO 13485:2003)., Pharmacotherapy:, Antidepressants:, - Venlafaxine 75-225 mg/d. N06AX16, - Duloxetine 60-120 mg/d. N06AX21, - Imipramine 100-300 mg/d. N06AA02, - Clomipramine 75-225 mg/d. N06AA04, - Nortriptyline 75-200 mg/d. 906AA10, - Sertraline 50-200 mg/d. N06AB06, -Fluoxetine 20-40 mg/d. N06AB03, - Citalopram 20-60 mg/d. N06AB04, - Paroxetine 20-40 mg/d. N06AB05, - Escitalopram 10-20 mg/d. N06AB10, - Mirtazapine 15-45 mg/d. N06AX11, - Mianserin 10-60 mg/d. 906AX03, - Trazadone 50-200 mg/d. 906AX05, - Reboxetin 2-12 mg/d. N06AX18, Antipsychotic drugs, - Olanzapine 2'5-20 mg/d. N05AH03, - Risperidone 0'5-9 mg/d. N05AX08, - Quetiapine 50-600 mg/d. N05AH04, - Aripiprazole 5-30 mg/d. N05AX12, Lithium: 200-1200 mg/d. 905AN01, Anxyiolitics:, - Diazepam 2'5-50 mg/d. N05BA01, - Clorazepate 5-50 mg/d. N05BA05, - Lorazepam 1-10 mg/d. N05BA06, PHARMACOTHERAPY | Hospital Universitari de Bellvitge | Depression | 07/14 | 07/14 | | |
NCT02350985: Comparison of Propranolol and Venlafaxine in Treatment of Vestibular Migraine |
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| Completed | 4 | 73 | RoW | Propranolol, Dideral, Venlafaxine, Efexor | Haseki Training and Research Hospital | Vestibular Migraine | 09/14 | 12/14 | | |
| Completed | 4 | 207 | Europe | Venlafaxine, Efexor, Sertraline | Charlotte Sonne, Psychiatric Center Ballerup | Post Traumatic Stress Disorder, Depression | 10/14 | 10/14 | | |
| Unknown status | 4 | 1080 | RoW | Escitalopram, Lexapro, Mirtazapine, Remeron, modified electroconvulsive therapy, mECT, repetitive transcranial magnetic stimulation, rTMS, Fluoxetine, Citalopram, Paroxetine, Sertraline, Fluvoxamine, Venlafaxine, Duloxetine, Bupropion, Trazodone | Shanghai Mental Health Center | Major Depressive Disorder | 10/14 | 12/14 | | |
| Unknown status | 4 | 80 | Europe | Paroxetine, Sertraline, Citalopram, Venlafaxine, Amitriptyline, Escitalopram, Amitriptylinoxide, Nortriptyline, Trimipramine | HolsboerMaschmeyer NeuroChemie GmbH, Max-Planck-Institute of Psychiatry | Major Depression | 12/14 | 12/14 | | |
2015-001639-19: Transcranial direct current stimulation and venlafaxine in the treatment of depression |
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| Ongoing | 4 | 60 | Europe | Capsule, hard, Venlafaxin Mylan 75 mg | Národní ústav duševního zdraví, Agentura pro zdravotnický výzkum České republiky | Depressive disorder, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Completed | 4 | 247 | US | lithium and Venlafaxine, ECT | Icahn School of Medicine at Mount Sinai, National Institute of Mental Health (NIMH) | Depression | 09/15 | 03/16 | | |
2008-000971-15: Evaluation of the effects of chronic treatment with venlafaxine (150 mg) and pregabalin (200 mg) on emotional indices of anxiety and panic induced by breathing carbon dioxide. |
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| Completed | 4 | 54 | Europe | Efexor, Lyrica, Efexor, Lyrica | University of Bristol | Generalised anxiety disorder | | 08/09 | | |
2006-004457-20: Evaluation de l\'action neuroréparatrice fonctionnelle et morphologique du traitement antidepresseur au cours de la rémission clinique dans la dépression recurrente. |
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| Ongoing | 4 | 88 | Europe | Stablon, Effexor, Norset, Stablon, Effexor, Norset, Stablon, Effexor, Norset, Stablon, Effexor, Norset | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP) | Dépression récurrente | | | | |
| Ongoing | 4 | 50 | Europe | Paroxetine, Amitriptyline, Clomipramine, Imipramine, Nortriptyline, escitalopram, Citalopram, Fluoxetine, Fluvoxamine, Sertraline, Duloxetine, venlafaxine, EU/1/04/296/002, Seroxat, Tryptizol, Anafranil, Imipramine, Nortrilen, Lexapro, Cipramil, prozac, Fevarin, Zoloft, Cymbalta, Efexor, Seroxat, Tryptizol, Anafranil, Imipramine, Nortrilen, Lexapro, Cipramil, prozac, Fevarin, Zoloft, Cymbalta, Efexor | Isala Klinieken | Pregnant women with psychiatric morbidity and an strong indication for using antidepressants | | | | |
2011-002727-18: The effects of switching antidepressants on endoxifen exposure |
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| Ongoing | 4 | 13 | Europe | Tamoxifen, Paroxetine, Escitalopram, Venlafaxine, RVG 09592, RVG 14668, RVG 30494, RVG 31854, Nolvadex, Seroxat, Lexapro, Efexor, Nolvadex, Seroxat, Lexapro, Efexor | | Breast cancer | | | | |
ChiCTR-OPC-17011266: The Efficacy of Venlafaxine, Flunarizine and Valproic acid in the Prophylaxis of Vestibular Migraine |
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| Completed | 4 | 75 | | venlafaxine ;flunarizine ;valproic acid | Qianfoshan Hospital of Shandong province; Qianfoshan Hospital of Shandong province, This study was supported by the Shandong Science & Technology development program of TCM (2013-195) and Shandong Science & Technology development program of medicine and health(2015WS0246) | Vestibular Migraine | | | | |
| Completed | 4 | 86 | US | Donepezil, Aricept, Placebo, Citalopram, Venlafaxine | New York State Psychiatric Institute, National Institute on Aging (NIA) | Depression, Mild Cognitive Impairment | 01/16 | 01/16 | | |
| Completed | 4 | 263 | US | Higher-dose venlafaxine, Effexor, Supportive management, Problem Solving Therapy for Depression and Pain, PST-DP | University of Pittsburgh | Depression, Back Pain | 02/16 | 02/16 | | |
NCT02714400: The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea |
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| Completed | 4 | 20 | US | Venlafaxine, Placebo | University of California, San Diego | Obstructive Sleep Apnea | 07/16 | 07/16 | | |
| Unknown status | 4 | 500 | Europe | SSRI/SNRI, citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine | Centre Hospitalier Universitaire Vaudois, University Hospital, Geneva, Hospices Civils de Lyon, Central Hospital, Nancy, France | Depressive Disorder, Lactation | 12/16 | 12/18 | | |
ChiCTR-OPC-15005947: The clinical response of Venlafaxine for patients with major depression disorder with LDQS and with DBHS:A case-control study |
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| Not yet recruiting | 4 | 75 | | Venlafaxine ;Venlafaxine ;Nil | Tongde Hospital of Zhejiang Province; Tongde Hospital of Zhejiang Province, First-phase Research Fund for Young Medical Investigators of Zhejiang Province; National Natural Science Foundation of China | Major Depression Disorder | | | | |
NCT01824433: Comparison of Venlafaxine and Fluoxetine in the Treatment of Postmenopausal Women With Major Depression |
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| Completed | 4 | 189 | RoW | venlafaxine, Efexor, fluoxetine, Prozac | Capital Medical University | Major Depression | 03/17 | 03/17 | | |
NMNTDM, NCT02346682: Neurochemical, Metabonomics and Neuroimaging Characterization of TCM Diagnostic Subtypes of Major Depression Disorder |
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| Unknown status | 4 | 75 | RoW | venlafaxine, clonazepam | Zhejiang Provincial Tongde Hospital, The University of Hong Kong | Severe Major Depression Disorder | 06/17 | 12/17 | | |
2016-003325-41: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) |
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| Ongoing | 4 | 450 | Europe | Syrup, Tablet, Capsule, hard, Powder for injection, Capsule, Solution for injection, Concentrate for solution for infusion, Powder for solution for infusion, Codeine, Acenocoumarol, Amitriptyline, Aripiprazole, Atomoxetine, Atorvastatine, Azathioprine, Capecitabine, Carbamazepine, Citalopram, Clomipramine, Clopidogrel, Clozapine, Efavirenz, Escitalopram, Flecainide, Flucloxacillin, Fluorouracil, Haloperidol, Irinotecan, Mercaptopurine, Metoprolol, Oxycodone, Paroxetine, Phenprocoumon, Phenytoin, ORAP 1 mg Tabletten, Propafenone, Sertraline, Simvastatin, Tacrolimus, Tamoxifen, Tegafur, Tioguanine, Tramadol, Venlafaxine, Voriconazole, Zuclopenthixol, Ethinylestradiol, ORAP 4 mg Tabletten | Leiden University Medical Center, Leiden University Medical Center | Adverse drug reactions, Side-effects, Not possible to specify | | | | |
ChiCTR2100048442: Clinical study of venlafaxine hydrochloride combined with tandospirone citrate in the treatment of vascular depression with somatization symptoms |
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| Completed | 4 | 136 | | Venlafaxine hydrochloride 75mg, once a day, if there are no adverse drug events, adjust to 150mg once a day in the second week. ;Venlafaxine hydrochloride 75mg, once a day, if there is no adverse drug event, adjust to 150mg once a day in the second week, and add tandospirone citrate 5mg once a day at the beginning of treatment 3 times, adjusted to 10mg in the second week, 3 times a day. | Union Hospital, Fujian Medical University; Union Hospital, Fujian Medical University, Sumitomo Pharmaceutical Co., Ltd | Vascular depression | | | | |
NCT02711215: Patient Stratification and Treatment Response Prediction in Neuropharmacotherapy Using Hybrid Positron Emmission Tomography/Magnetic Resconance Imaging (PET/MR) |
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| Unknown status | 4 | 80 | Europe | PET/MR [11C]DASB, Hybrid imaging, Molecular imaging, SERT binding potential, Citalopram, Seropram, Escitalopram (Mirtazapine/Duloxetine/Venlafaxine), Cipralex, Placebo, Saline, NaCL | Medical University of Vienna | Major Depressive Disorder | 01/20 | 01/20 | | |
ChiCTR1900021496: A study for efficacy of venlafaxine add on in treatment of inflammatory bowel disease patients with depression/anxiety. |
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| Not yet recruiting | 4 | 30 | | Take 75mg of venlafaxine once daily in week 1;After one week, take venlafaxine 150mg once daily for nine months ;Placebo | West China Hospital, Sichuan University; West China Hospital, Sichuan University, Clinical research incubation project foundation of West China Hospital,Sichuan University | inflammatory bowel disease | | | | |
NCT04207385: Accurate Clinical Study of Medication in Patients With Depression Via Pharmacogenomics (PGx) and Therapeutic Drug Monitoring (TDM) of Venlafaxine |
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| Unknown status | 4 | 160 | RoW | pharmacogenomics, pharmacogenomics & therapeutic drug monitoring, Venlafaxine | Xijing Hospital | Depression | 08/21 | 11/21 | | |
NCT05569031: Treatment of Withdrawal Symptoms and Prevention of Relapse in Patients With Tramadol Abuse |
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| Completed | 4 | 52 | RoW | Venlafaxine, Lofexidine | Zagazig University | Opiate Withdrawal Syndrome | 12/21 | 06/22 | | |
| Recruiting | 4 | 30 | Europe | Venlafaxine | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Major Depressive Disorder, Bipolar Affective Disorder, Currently Depressed, Moderate | 03/24 | 04/24 | | |
2021-006800-34: Phase IV interventional pharmacological study to identify the changes in neuroplasticity at the cellular, molecular and neural level that occur in patients with major depression following the introduction of drug therapy with venlafaxine. Studio interventistico farmacologico di fase IV per identificare i cambiamenti di neuroplasticità a livello cellulare, molecolare e neurale che si verificano nei pazienti con depressione maggiore in seguito all’introduzione della terapia farmacologica con venlafaxina. |
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| Not yet recruiting | 4 | 30 | Europe | ZARELIS - 75 MG COMPRESSE A RILASCIO PROLUNGATO, [Venlafaxina], Prolonged-release tablet, ZARELIS - 75 MG COMPRESSE A RILASCIO PROLUNGATO 14 COMPRESSE IN BLISTER PVC/PCTFE/AL | FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Fondazione Cariplo - Bando di ricerca 2019 “Ricerca sulla Sindrome ansioso-depressiva: prevenzione, diagnosi precoce e t | patients with major depression Pazienti affetti da depressione maggiore, Mental disorder Disturbo mentale, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT05023278: The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement |
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| Recruiting | 4 | 100 | US | Venlafaxine 37.5 MG, SNRI analgesia, Placebo, control | University of California, San Francisco, Orthopedic Research and Education Foundation | Acute Pain, Chronic Pain, Knee Pain Chronic, Neuropathic Pain | 12/24 | 03/25 | | |
| Recruiting | 4 | 60 | RoW | Venlafaxine 75 MG, Gabapentin 400 mg | Mit Ghamr Oncology Center | Peripheral Neuropathy Due to Chemotherapy | 10/23 | 12/23 | | |
| Active, not recruiting | 4 | 700 | US | Selective serotonin reuptake inhibitor, Serotonin-norepinephrine reuptake inhibitor, Written Exposure Therapy | University of Washington, Stanford University, Boston University, Washington State University, Patient-Centered Outcomes Research Institute | PTSD | 08/24 | 12/25 | | |
NCT04977271: Mood Disorders in Head and Neck Cancer Patients |
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| Not yet recruiting | 4 | 205 | US | Venlafaxine, Effexor | University of Alabama at Birmingham | Depressive Disorder, Head and Neck Cancer | 09/26 | 09/28 | | |
ACTRN12619001082190: Serotonin Noradrenaline Reuptake Inhibitors (SNRI) medications for the treatment of osteoarthritis pain (STOP) trial |
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| Recruiting | 3/4 | 146 | | | Waitemata District Health Board, Health Research Council of New Zealand | Knee osteoarthritis | | | | |
