| escitalopram / Generic mfg. |
NCT01024140: Open Trial of Escitalopram Treatment for Male Subjects With Posttraumatic Stress Disorder |
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| Completed | N/A | 16 | US | Escitalopram, Lexapro | Northern California Institute of Research and Education | Chronic Posttraumatic Stress Disorder | 12/04 | 12/04 | | |
NCT00255554: DBT and Escitalopram in Borderline Personality Disorder |
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| Unknown status | N/A | | US | Dialectical Behavioral Therapy, Escitalopram | Bronx VA Medical Center | Borderline Personality Disorder | | | | |
| Completed | N/A | 61 | Europe | rTMS, TMS | Hillerod Hospital, Denmark, Medicon Valley Academy | Major Depression | | 01/06 | | |
NCT00223288: Impact of Caregiver Depression on Asthma in the Child |
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| Completed | N/A | 175 | US | Lexapro | University of Texas Southwestern Medical Center | Depressive Disorder, Major, Asthma | 02/06 | 02/06 | | |
NCT00206934: The Effects of Increased Central Serotonergic Activity on Information Processing |
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| Completed | N/A | 40 | Europe | Escitalopram, Cipralex, escitaolpram | University of Copenhagen, Lundbeck Foundation, Glostrup University Hospital, Copenhagen | Healthy Volunteers | 03/06 | 03/06 | | |
NCT00150527: Specific Effects of Escitalopram on Neuroendocrine Response |
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| Completed | N/A | 8 | Canada | Citalopram, Celexa, Escitalopram, Dexamethasone, Cold Pressor Test | Queen's University, H. Lundbeck A/S | Healthy | 12/06 | 12/07 | | |
| Completed | N/A | 40 | US | Lexapro, an antidepressant medicine, Physical Activity, Mood Management Skills, Personalized support from a Family Nurse Practitioner | University of California, San Diego, Forest Laboratories | Depression | | 01/07 | | |
NCT00194948: Treatment Choices for Improving Adherence and Outcome |
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| Completed | N/A | 60 | US | escitalopram, interpersonal psychotherapy | Weill Medical College of Cornell University, National Institute of Mental Health (NIMH) | Major Depression | 04/07 | 05/07 | | |
NCT00277108: Lexapro in the Treatment of Patients With Postpartum Depression |
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| Completed | N/A | 20 | US | Escitalopram (Lexapro) | University of Rochester, Forest Laboratories | Postpartum Depression | 04/07 | 04/07 | | |
NCT00289523: EEG Biomarkers for Predicting Response to Antidepressant Therapy |
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| Completed | N/A | 375 | US | | Medtronic - MITG | Major Depressive Disorder | 07/07 | 07/07 | | |
NCT00532519: Effectiveness of the Selective Serotonin Reuptake Inhibitor,Citalopram (Cipralex), in Prurigo Nodularis |
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| Unknown status | N/A | | RoW | citalopram (cipralex) | Hadassah Medical Organization | Prurigo Nodularis | | | | |
NCT00749125: fMRI Studies of Emotional Brain Circuitry in People With Major Depression |
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| Completed | N/A | 99 | NA | Lexapro, Escitalopram | Washington University School of Medicine, National Institute of Mental Health (NIMH) | Depression | 01/08 | 06/08 | | |
NCT00146900: Prevention of Post Traumatic Stress Disorder by Early Treatment |
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| Completed | N/A | 298 | RoW | Cognitive Behavioral Therapy, Cognitive Therapy, Escitalopram, SSRI, Placebo | Hadassah Medical Organization | Post-traumatic Stress Disorder | 01/08 | 01/08 | | |
NCT00295347: Mineralocorticoid Receptor in the Treatment of Severe Depression |
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| Completed | N/A | 65 | Europe | Spironolactone, fludrocortisone, escitalopram | Universitätsklinikum Hamburg-Eppendorf | Major Depression | 06/08 | 06/08 | | |
NCT00598052: Treatment of Marijuana Withdrawal Syndrome Using Escitalopram and Cognitive-Behavior Therapy |
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| Unknown status | N/A | 40 | RoW | Escitalopram, Cipralex | Tel-Aviv Sourasky Medical Center | Marijuana Dependence | 10/08 | 10/08 | | |
| Completed | N/A | 201 | US | Problem Solving Therapy, Escitalopram, Lexapro, Placebo | Robert G. Robinson, National Institute of Mental Health (NIMH) | Depression, Cerebrovascular Accident | 11/08 | 11/08 | | |
NCT00232700: Investigation of a Combination Treatment of Escitalopram and rTMS |
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| Completed | N/A | 42 | Europe | Escitalopram | Charite University, Berlin, Germany, H. Lundbeck A/S | Major Depressive Disorder | 12/08 | 12/08 | | |
NCT00630981: Psychotherapy and Pharmacotherapy in Dissociative Disorders |
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| Unknown status | N/A | 30 | Europe | Psychotherapy, Dissociative Disorders, Pharmacological treatment (Quetiapine and/or Escitalopram), Seroquel, Ketipinor, Lexapro, Cipralex | Espace Hogan | Dissociative Disorders | 04/09 | 07/09 | | |
| Completed | N/A | 450 | RoW | Escitalopram, Placebo | Sheba Medical Center | Post-traumatic Stress Disorder | 05/09 | 05/09 | | |
NCT01527474: Escitalopram in the Treatment of Postpartum Depression |
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| Completed | N/A | 20 | Canada | escitalopram | BC Women's Hospital & Health Centre | Postpartum Depression | 05/09 | 05/09 | | |
NCT00384020: Clinical Pharmacogenomics of Antidepressant Response |
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| Completed | N/A | 402 | RoW | Paroxetine (Seroxat), Escitalopram (Lexapro) | National Health Research Institutes, Taiwan, National Science Council, Taiwan, Chang Gung Memorial Hospital, Taipei Medical University WanFang Hospital, Taipei City Hospital, Mackay Memorial Hospital | Depression | 01/10 | 01/10 | | |
NCT00643162: Combination Lexapro and Massage for Treatment of Depression in Older Adults |
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| Terminated | N/A | 17 | US | Lexapro, Escitalopram, Light touch, Massage | Cedars-Sinai Medical Center, Forest Laboratories | Depression | 02/10 | 02/10 | | |
NCT00736021: Treatment of Post-traumatic Stress Disorder With High Doses of Escitalopram |
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| Completed | N/A | 38 | RoW | Escitalopram, Lexapro, Cipralex | Hadassah Medical Organization | Stress Disorders, Post Traumatic | 03/10 | 03/10 | | |
| Completed | N/A | 35 | RoW | escitalopram, lexapro | Inje University | Generalized Anxiety Disorder | 04/10 | 05/10 | | |
NCT00926653: Assessing Anterior Cingulate Brain Activity in People With Late-Life Depression |
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| Completed | N/A | 76 | US | Escitalopram, Lexapro | Weill Medical College of Cornell University | Depression | 05/10 | 05/10 | | |
NCT00101452: Safety and Effectiveness of S-adenosyl-l-methionine (SAMe) for the Treatment of Major Depression |
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| Completed | N/A | 199 | US | S-adenosyl-l-methionine, SAMe, Escitalopram, Lexapro, Placebo | Maurizio Fava, MD, National Center for Complementary and Integrative Health (NCCIH) | Depression | 06/10 | 06/10 | | |
NCT00944996: Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression |
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| Completed | N/A | 100 | RoW | SSRI; SNRI; TCA, paroxetine, fluoxetine, sertraline, escitalopram, citalopram, mirtrazapine, venlafaxine, anafranil | Tirat Carmel Mental Health Center, University of Michigan, Ariel University, The Nazareth Hospital, Israel | Major Depression | 06/10 | 07/12 | | |
NCT00894543: MsFLASH-01: Escitalopram for Menopausal Symptoms in Midlife Women |
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| Completed | N/A | 205 | US | Escitalopram, Lexapro®., Placebo | Fred Hutchinson Cancer Center, National Institute on Aging (NIA), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Center for Complementary and Integrative Health (NCCIH), Office of Research on Women's Health (ORWH) | Hot Flashes, Menopause, Vasomotor Symptoms | 06/10 | 06/10 | | |
NCT00746239: Ramelteon for Sleep Initiation Insomnia in Individuals With Panic Disorder Who Are Also on Escitalopram for Anxiety |
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| Terminated | N/A | 11 | US | Placebo and Escitalopram, Ramelteon and Escitalopram | Milton S. Hershey Medical Center, Takeda Pharmaceuticals North America, Inc. | Panic Disorder, Insomnia | 07/10 | 07/10 | | |
NCT00636649: Escitalopram Treatment of Night Eating Syndrome |
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| Completed | N/A | 40 | US | Escitalopram, Placebo | Duke University, St. Louis University | Night Eating Syndrome | 08/10 | 07/11 | | |
NCT00711737: Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months |
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| Completed | N/A | 27 | RoW | | Changi General Hospital | Major Depression, Generalized Anxiety Disorder, Panic Disorder | 10/10 | 10/10 | | |
NCT00702598: The WORKER Study: Escitalopram and Telephone-based Cognitive Behaviour Therapy (CBT) for Depressed Working People |
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| Completed | N/A | 105 | Canada | Telephone-based Cognitive Behaviour Therapy (CBT), Telephone reminder calls | University of British Columbia | Major Depressive Disorder (MDD) | 04/11 | 12/11 | | |
NCT00220480: A Naturalistic Study of the Efficacy and Safety of Escitalopram in Treatment Resistant Depression |
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| Unknown status | N/A | 60 | RoW | escitalopram | Sheba Medical Center | Depressive Disorder, Major | 06/11 | | | |
NCT00703742: A Neuroimaging and Epigenetic Investigation of Antidepressants in Depression |
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| Completed | N/A | 200 | RoW | Escitalopram | Kunming Medical University, Chinese Academy of Sciences | Depression, Depression Secondary to Other Disease | 06/11 | 06/11 | | |
NCT00367341: Imaging Predictors of Treatment Response in Depression |
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| Completed | N/A | 82 | US | escitalopram, Lexapro, Cognitive Behavioral Therapy (CBT), Talk Therapy | Emory University, National Institute of Mental Health (NIMH) | Major Depressive Disorder | 08/11 | 07/13 | | |
NCT00601965: Antidepressant Treatment Plus Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Older Adults |
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| Completed | N/A | 73 | US | Escitalopram, Lexapro, Placebo, Sugar pill, Cognitive behavioral therapy (CBT), CBT | Veterans Medical Research Foundation, National Institute of Mental Health (NIMH) | Generalized Anxiety Disorder | 09/11 | 09/11 | | |
| Completed | N/A | 74 | RoW | escitalopram, Lexapro, placebo | Seoul National University Hospital, H. Lundbeck A/S | Alzheimer's Disease | 09/11 | 09/11 | | |
LBW-SSRI, NCT00971815: Effects of 3 Months of Selective Serotonin Reuptake Inhibitor (SSRI)-Treatment on Metabolism and Hypothalamic-pituitary-adrenal (HPA)-Axis in Young Men Born With Low Birth Weight |
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| Completed | N/A | 60 | Europe | Escitalopram, Escitalopram (Cipralex)(H. Lundbeck A/S), placebo, no other names | University of Aarhus | Insulin Resistance, Low Birth Weight, Type 2 Diabetes, Cardiovascular Disease, Melancholic Depression, Anxiety Disorders | 09/11 | 04/14 | | |
NCT00935246: Development of Escitalopram Genomic Device by Using Candidate Gene Approach and Genome-Wide Scanning |
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| Unknown status | N/A | 202 | RoW | Escitalopram, Escitalopram : Lexapro | Samsung Medical Center, H. Lundbeck A/S | Depression, Continuous Antidepressant Abuse, Adverse Reaction to Drug | 10/11 | 12/16 | | |
NCT01404871: Predicting Medication Response in Obsessive Compulsive Disorder |
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| Completed | N/A | 26 | Canada | clomipramine, Anafranil, escitalopram, Cipralex, duloxetine, Cymbalta | Sunnybrook Health Sciences Centre, Obsessive Compulsive Foundation, Centre for Addiction and Mental Health | Obsessive Compulsive Disorder | 10/11 | 12/11 | | |
| Completed | N/A | 19 | US | placebo/escitalopram, Lexapro, escitalopram | Oregon Health and Science University, Forest Laboratories | Depression | 12/11 | 12/11 | | |
NCT00989053: The Effect of Selective Serotonin Reuptake Inhibitor (SSRI) Treatment on Affective Symptoms and Fertility Treatment Outcome in Women Undergoing in Vitro Fertilization (IVF) |
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| Unknown status | N/A | 120 | RoW | escitalopram, placebo | Tel-Aviv Sourasky Medical Center | Depression, Anxiety, In Vitro Fertilization | 01/12 | 01/12 | | |
rTMS, NCT01115699: Study of Repetitive Transcranial Magnetic Stimulation () as Adjuvant Treatment for Depression |
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| Terminated | N/A | 2 | US | Repetitive Transcranial Magnetic Stimulation (rTMS) | Mayo Clinic, Neuronetics | Depression | 03/12 | 03/12 | | |
NCT00456014: Pre-Treatment Positron Emission Topography Scanning for Increasing Success in Antidepressant Treatment |
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| Completed | N/A | 37 | US | Escitalopram, Lexapro, Desipramine, Norpramin | New York State Psychiatric Institute, National Institute of Mental Health (NIMH) | Depression | 05/12 | 05/12 | | |
NCT00953745: Dopaminergic Effects of Adjunctive Aripiprazole on the Brain in Treatment-Resistant Depression |
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| Completed | N/A | 43 | US | Escitalopram, Lexapro, Aripiprazole, Abilify, Placebo Capsule, Placebo Tablet | Washington University School of Medicine, Bristol-Myers Squibb | Major Depressive Disorder | 06/12 | 12/12 | | |
NCT02480400: The Effect of Patient and Investigator Expectation on the Efficacy of Escitalopram in the Treatment Depression |
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| Completed | N/A | 52 | RoW | Escitalopram, Cipralex, Lexapro | Abarbanel Mental Health Center, H. Lundbeck A/S | Major Depressive Disorder | 06/12 | 10/12 | | |
| Unknown status | N/A | 150 | Canada | Venlafaxine, Effexor, bupropion, Wellbutrin, escitalopram, Cipralex, Psychotherapy, CBT, Duloxetine, Cymbalta | St. Joseph's Healthcare Hamilton | Major Depressive Disorder | 10/12 | 10/13 | | |
NCT01488266: Aripiprazole Augmentation Versus Switching to Different Class of Antidepressants in Major Depressive Disorder |
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| Unknown status | N/A | 90 | RoW | Aripiprazole, abilify, switching to different class of antidepressant, escitalopram, fluoxetine, paroxetine, sertraline, bupropion XL, mirtazapine, venlafaxine, milnacipran, duloxetine | Korea University, Korea OIAA, Taiwan Otsuka Pharm. Co., Ltd | Major Depressive Disorder | 01/13 | 03/13 | | |
| Completed | N/A | 23 | US | PET scan and MRI scan | Massachusetts General Hospital | Body Dysmorphic Disorder | 03/13 | 03/13 | | |
| Unknown status | N/A | 25 | RoW | Escitalopram, Lexapro | Beitou Armed Forces Hospital, Taipei, Taiwan | Depression | 04/13 | 04/13 | | |
NCT00517764: Childhood Adversity, Genetic Polymorphisms and Stress in First Onset Major Depression |
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| Completed | N/A | 299 | Canada | escitalopram, Lexapro, Cipralex, S-citalopram | Centre for Addiction and Mental Health, Queen's University | Depression | 06/13 | 06/13 | | |
NCT01936051: Modeling Between Plasma Concentration and Serotonin Transporter Occupancy Induced by Escitalopram in Obsessive-compulsive Disorder(OCD) Patients |
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| Completed | N/A | 12 | RoW | | Seoul National University Hospital | OCD | 10/13 | 12/13 | | |
NCT00620789: Behavioral Insomnia Therapy For Those With Insomnia and Depression |
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| Unknown status | N/A | 477 | Canada | Escitalopram + CBT-I, Escitalopram,Lexipro, CBT-I, Cognitive Behavioral Therapy-Insomnia, CBT-I plus placebo antidepressant medication, CBT-I, Cognitive Behavioral Therapy Insomnia, Escitalopram, Escitalopram, Lexipro, SH,Sleep Hygiene | Ryerson University | Insomnia, Major Depressive Disorder | 01/14 | 01/14 | | |
| Completed | N/A | 47 | Europe | cipralex | RWTH Aachen University | Healthy Volunteers | 02/14 | 06/14 | | |
NCT00667121: Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline |
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| Active, not recruiting | N/A | 85 | US | citalopram hydrobromide, escitalopram oxalate, gabapentin, sertraline hydrochloride, tamoxifen citrate, venlafaxine, molecular genetic technique, high performance liquid chromatography, laboratory biomarker analysis, pharmacological study, adjuvant therapy | Mayo Clinic, National Cancer Institute (NCI) | Breast Cancer, Depression, Hot Flashes, Psychosocial Effects of Cancer and Its Treatment | 05/14 | 12/24 | | |
NCT01896349: Interpersonal Psychotherapy for Treatment Resistant Depression |
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| Unknown status | N/A | 74 | RoW | IPT+ antidepressant drugs, Interpersonal Psychotherapy, Antidepressant drugs, fluoxetine, sertraline, paroxetine, Citalopram, escitalopram, fluvoxamine, Venlafaxine, Duloxetine, Bupropion, Lithium, Risperidone, tranylcypromine, Imipramine, amitriptyline, Clomipramine, nortriptyline, trazodone, Mirtazapine, sulpiride | Hospital de Clinicas de Porto Alegre | Treatment Resistant Depression | 08/14 | 11/14 | | |
| Completed | N/A | 3255526 | Canada | Duloxetine, Venlafaxine, Desvenlafaxine, Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline | Canadian Network for Observational Drug Effect Studies, CNODES, Drug Safety and Effectiveness Network, Canada, Canadian Institutes of Health Research (CIHR) | Depression, Acute Kidney Injury | 12/14 | 12/14 | | |
NCT00360399: Identifying Factors That Predict Antidepressant Treatment Response |
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| Completed | N/A | 344 | US | Escitalopram, Lexapro, Duloxetine, Cymbalta, Cognitive behavioral therapy (CBT) | Emory University, National Institute of Mental Health (NIMH) | Depression | 04/15 | 04/15 | | |
| Completed | N/A | 106 | US | Escitalopram, Lexapro | Weill Medical College of Cornell University, National Institute of Mental Health (NIMH), Forest Laboratories | Depression | 05/15 | 05/15 | | |
NCT01538693: Molecular Markers of Neuroplasticity During Exercise in People With Incomplete Spinal Cord Injury |
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| Completed | N/A | 30 | US | escitalopram oxalate, Lexapro, Cyproheptadine, sugar pill, Graded intensity exercise | T. George Hornby, University of Medicine and Dentistry of New Jersey, Shirley Ryan AbilityLab | Spinal Cord Injury | 05/15 | 05/15 | | |
ChiCTR-TRC-14004936: Ketamine's antidepressant efficacy and safety in major depression: a randomized controlled trial |
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| Completed | N/A | 30 | | receive a single intravenous infusion of Ketamine+oral Escitalopram Oxalate Tablets 10mg/d four weeks ;receive a single intravenous infusion of 0.9% saline + +oral Escitalopram Oxalate Tablets 10mg/d four weeks | Beijing Chaoyang Hospital; Beijing Chaoyang Hospital, Ministry of Science and Technology; Beijing Municipal Administration of Hospitals | depression disorder | | | | |
NCT02423694: Effectiveness and Safety of Electro-acupuncture for Mild-to-moderate Perimenopausal Depression |
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| Unknown status | N/A | 252 | RoW | electro-acupuncture, escitalopram oxalate tablets | Guangdong Provincial Hospital of Traditional Chinese Medicine | Perimenopause, Depression | 12/15 | | | |
NCT02285699: The Gut Microbiota in Obsessive-Compulsive Disorder |
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| Completed | N/A | 43 | Canada | SSRIs, Fluoxetine, Paroxetine, Fluvoxamine, Escitalopram, Citalopram, Sertraline | McMaster University, Hamilton Health Sciences Corporation | Obsessive-Compulsive Disorder | 03/16 | 03/16 | | |
NCT02579343: Adjunctive Treatment of Major Depression Utilizing Auricular Acupuncture |
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| Completed | N/A | 13 | US | Auricular Acupuncture, Pointer Excel II, Sham Auricular Acupuncture + Lexapro, SSRI Lexapro | Florida Gulf Coast University | Major Depressive Disorder | 05/16 | 05/16 | | |
ChiCTR-INR-17011986: Combination of Escitalopram and antipsychotic improve negative symptoms of refractory schizophrenia |
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| Completed | N/A | 62 | | escitalopram ;placebo | Shandong Mental Health Center; Shandong Mental Health Center, personage | Refractory schizophrenia | | | | |
ChiCTR-IOR-16008327: A clinical evaluation research for the treatment of major depression by integrated Disease with Zheng of TCM method |
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| Recruiting | N/A | 320 | | Escitalopram ;Escitalopram ;Liver resolve depression particles ;acupuncture | southern medical university; Guang'anmen Hospital, national sci-tech support plan | major depression disease | | | | |
NCT02934035: Early Improvement in Individual Symptoms and Response to Antidepressants in Patients With Major Depressive Disorder |
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| Unknown status | N/A | 10000 | NA | Antidepressant, Duloxetine, Paroxetine, Escitalopram, Fluoxetine, Venlafaxine | University Medical Center Groningen | Major Depressive Disorder | 09/17 | 09/17 | | |
| Completed | N/A | 51 | US | Escitalopram, Lexapro, Cipralex, Seroplex, Lexamil, Lexam, Healthy Control | Wyss Institute at Harvard University, Massachusetts General Hospital, Martinos Center for Biomedical Imaging, Massachusetts Institute of Technology | Major Depressive Disorder | 10/17 | 10/17 | | |
NCT03554447: Role of Pentoxifylline as an Adjuvant Therapy for Adult Patients With Major Depressive Disorder |
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| Completed | N/A | 80 | NA | Escitalopram 20 mg tablet plus Pentoxifylline 400Mg Tablet, Escitalopram 20 mg tablet + Placebo | Mahmoud Samy Abdallah | Major Depressive Disorder | 12/17 | 12/18 | | |
NCT02441387: Predictors of the Outcome of Late Life Depression |
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| Unknown status | N/A | 120 | RoW | Antidepressant, zoloft, lexapro, efexor, remeron, carbolithium, Psychoeducation, Treatment as usual (only pharmacological treatment). | University of Sao Paulo General Hospital, Fundação de Amparo à Pesquisa do Estado de São Paulo | Major Depression | 03/18 | 07/19 | | |
NCT04013464: Effects of Escitalopram on the Sleep EEG Power in Patients With Major Depressive Disorder |
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| Completed | N/A | 31 | NA | Escitalopram, no other intervention | Peking University Sixth Hospital, National Institute on Drug Dependence, China | Depressive Disorder, Major | 05/18 | 12/18 | | |
NCT00550485: Pharmacokinetic and Pharmacodynamic Effects of Escitalopram Depending on Genetic Polymorphisms of the ABCB1-gene |
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| Completed | N/A | 79 | Europe | escitalopram | Max-Planck-Institute of Psychiatry | Pharmacokinetics | 07/18 | 07/18 | | |
NCT03547219: Biomarkers of Antidepressant Response and Suicidal Events in Depressed Youth |
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| Completed | N/A | 152 | RoW | Escitalopram, Lexapro | Seoul National University, National Research Foundation of Korea | Depression, Adolescent | 08/18 | 08/18 | | |
ChiCTR-IPR-17013173: Chinese medicine Chaihu-jia-Longgu-Muli-tang in the treatment of depression: a multi-center, randomized, open lable, controlled trial |
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| Recruiting | N/A | 150 | | Chaihu-jia-Longgu-Muli-tang ;Chai Mu jiaqiang Decoction ;Escitalopram ;Chaihu-jia-Longgu-Muli-tang+Escitalopram ;Lorazepam+Escitalopram | Nanjing University of Chinese Medicine; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Science and technology project of Jiangsu Provincial Bureau of traditional Chinese Medicine | Depression | | | | |
ChiCTR-IOR-15007551: Observe the Synchronism of Brain Network-Gene Expression in Treating Depression with Electro-acupuncture |
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| Not yet recruiting | N/A | 240 | | acupuncture and Escitalopram ;acupuncture ;Escitalopram | Peking University Sixth Hospital; Beijing University of Chinese Medicine, Natural Science Foundation of China | Depression | | | | |
| Completed | N/A | 138 | US | Escitalopram, Lexapro, Placebo oral tablet, placebo | New York State Psychiatric Institute | Major Depressive Disorder | 01/19 | 01/20 | | |
FiESTAA, NCT02818751: Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety |
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| Completed | N/A | 84 | US | Escitalopram, Lexapro, Placebo, Sugar Pill | University of Cincinnati, National Institute of Mental Health (NIMH) | Anxiety | 05/19 | 05/20 | | |
NCT02893371: Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies |
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| Terminated | N/A | 1037352 | US | Lithium Carbonate, Lithobid, Lamotrigine, Lamictal, Valproic Acid, Depakote, Valproate, Oxcarbazepine, Trileptal, Carbamazepine, Equetro, Ziprasidone, Geodon, Risperidone, Risperdal, Quetiapine, Seroquel, Olanzapine, Zyprexa, Aripiprazole, Abilify, Fluoxetine / Olanzapine, Symbyax, Haloperidol, Haldol Decanoate, Perphenazine, Trilafon, Clozapine, Clozaril, Asenapine, Saphris, Lurasidone, Latuda, Paliperidone, Invega, Mirtazapine, Remeron, Remeronsoltab, Bupropion, Zyban, Aplenzin, Wellbutrin, Desvenlafaxine, Pristiq, Desfax, Duloxetine, Cymbalta, Irenka, Venlafaxine, Effexor XR, Citalopram, Celexa, Escitalopram, Lexapro, Fluoxetine, Prozac, Sarafem, Fluvoxamine, Faverin, Fevarin, Floxyfral, Dumyrox, Luvox, Paroxetine, Paxil, Seroxat, Sertraline, Zoloft, Vilazodone, Viibryd, Doxepin, Sinequan, Silenor | University of New Mexico, Patient-Centered Outcomes Research Institute, Montana State University, National Alliance on Mental Illness Montana, CGStat LLC, Risk Benefit Statistics LLC, National Alliance on Mental Illness New Mexico, National Alliance on Mental Illness Westside Los Angeles | Bipolar Disorder | 06/19 | 06/19 | | |
ChiCTR1900023492: A comparative study for the effects of escitalopram and duloxetine on anhedonia in depression |
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| Completed | N/A | 40 | | Escitalopram ;Duloxetine | ZhongDa Hospital, School of Medicine, Southeast University; ZhongDa Hospital, School of Medicine, Southeast University, Nanjing special fund for scientific and technological development | Major depressive disorder | | | | |
ChiCTR1800020242: Different frequencies repetitive transcranial magnetic stimulation in combination with escitalopram in female patients with somatoform disorder: single-blind, randomised, case-controlled study |
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| Recruiting | N/A | 90 | | Escitalopram treatment ;10Hz rTMS plus Escitalopram treatment ;1Hz rTMS plus Escitalopram treatment | Affiliated mental health center, Tongji Medical College of Huazhong University of Science and Technology (HUST); Affiliated mental health center, Tongji Medical College of Huazhong University of Science and Technology (HUST), 2017 scientific study project of Health and Family Planning Commission of Wuhan Municipality | somatoform disorder | | | | |
ChiCTR1900021114: A Randomized, Double Blind, Controlled Trial for the Effect of Yueju Pill in The Treatment of Patient with Depression |
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| Recruiting | N/A | 51 | | YUEJU PILL 12g/day+placebo ;YUEJU PILL 23g/day（week1）12g/day(week2-4)+placebo ;ESCITALOPRAM 10mg/day+placebo | The Fourth People's Hospital of Taizhou; Nanjing University of Traditional Chinese Medicine, Taizhou science and technology support(Social Development) plan for 2016/TS201612 | Depression | | | | |
NCT02516332: Exercise and Pharmacotherapy for Anxiety in Cardiac Patients |
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| Completed | N/A | 128 | US | Lexapro, Placebo, Supervised Aerobic Exercise | Duke University | Anxiety, Cardiovascular Disease | 05/20 | 05/21 | | |
ChiCTR1900026204: Canceled by the investigator. Effectiveness of rTMS in stimulating the V1 area of visual cortex versus classical target area in patients with depression: a randomized, double-blind, non-inferiority trial |
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| Suspended | N/A | 70 | | rTMS therapy (L-DLPFC)+ Escitalopram oxalate tablets (10mg/d) ;rTMS therapy (left V1 area) + Escitalopram oxalate tablets (10mg/d) | Zhongda Hospital; Zhongda Hospital, Self-financing | depression | | | | |
ChiCTR2000029450: The efficacy and safety of bright light therapy combined with escitalopram oxalate in the treatment of sleep disorders associated with post-stroke depression |
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| Recruiting | N/A | 110 | | escitalopram oxalat, 10 mg,qm ;escitalopram oxalat, 10 mg,qm and BLT 30min qd | The First Affiliated Hospital of Wenzhou Medical University; The First Affiliated Hospital of Wenzhou Medical University, self-financing | Post-stroke depression | | | | |
ChiCTR1800017626: A precision medicine study on the treatment of depression using Venlafaxine and Escitalopram |
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| Recruiting | N/A | 4200 | | oral administration of Venlafaxine (75-225 mg/day) ;oral administration of Escitalopram (10-20 mg/day) | Zhejiang University; The First Affliated Hospital, Zhejiang University School of Medicine, National Key Research and Development Plan, Precision Medicine Research Key Special Project | Depression | | | | |
ChiCTR2000031719: Application of Objective Indicators Based on Mobile Technology in Clinical Evaluation of Depression |
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| Recruiting | N/A | 60 | | Escitalopram | Beijing Anding Hospital Affiliated to Capital Medical University; The National Clinical Research Center for Mental Disorders, Beijing Anding Hospital Capital Medical University, Beijing Municipal Administration of Hospitals' Youth Programme (QML20181904) | Major Depressive Disorder | | | | |
NCT04037111: Clinical Study of Escitalopram Oxalate Combined With taVNS in Depression and Concomitant Inflammatory Symptoms |
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| Unknown status | N/A | 90 | RoW | Transcutaneous electrical vagus nerve stimulation, VNS stimulated once a day for 30 minutes each time with a stimulating intensity of 1-2 mA., Sham vagus nerve stimulation, drug treatment | Xijing Hospital | Major Depressive Disorder, Rheumatoid Arthritis | 01/21 | 12/21 | | |
ChiCTR2100044520: Pretest of Pharmacokinetic of Escitalopram Oxalate Tablets in healthy subjects |
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| Recruiting | N/A | 8 | | Delivery order | Dongyang Hengdian hospital; Zhejiang Baidai Pharmaceutical Technology Co., Ltd., Zhejiang Baidai Pharmaceutical Technology Co., Ltd. | Pharmacokinetic study | | | | |
NCT03841474: The Recovery of Cardiovascular Patients With Depression |
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| Recruiting | N/A | 150 | RoW | Psychiatric treatment with sertraline, Intervention I, Psychiatric treatment with escitalopram, Intervention II | KliniÄki BolniÄki Centar Zagreb | Coronary Artery Disease, Depression, Cardiovascular Diseases | 06/21 | 11/21 | | |
ChiCTR1800018063: Application of transcranial direct current stimulation in depression treatment |
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| Not yet recruiting | N/A | 160 | | Pseudo stimulus + placebo ;Pseudo stimulus + Escitalopram ;tDCS + placebo ;tACS + placebo | Shanghai Mental Health Center; Shanghai Mental Health Center, Shanghai Shenkang Hospital Development Center Clinical Science and Technology Innovation Project | depression | | | | |
NCT03294525: Towards Neurobiology-based Diagnosis and Treatment of Affective Disorders |
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| Recruiting | N/A | 400 | RoW | Escitalopram Pill, Lexapro, Duloxetine, Cymbalta, Mirtazapine Pill, Remeron, Other Antidepressants | Peking University | Affective Disorder | 12/21 | 08/22 | | |
NCT03346239: Effect of Attention Training or SSRIs on Symptoms and Neural Activation in Social Anxiety |
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| Completed | N/A | 105 | RoW | Gaze Contingent Music Reward Therapy, Escitalopram, Cipralex, Waitlist | Tel Aviv University, Sheba Medical Center, Tel-Aviv Sourasky Medical Center | Social Anxiety Disorder | 12/21 | 12/21 | | |
NCT03148522: A Diagnosis and Treatment Optimization Study of Depression Based on the Neurological Mechanism of Reward System |
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| Unknown status | N/A | 120 | RoW | Escitalopram, Duloxetine, Mirtazapine | Peking University | Diagnosis and Treatment of Depression | 12/21 | 06/22 | | |
NCT03899194: Study on the Effect of PRKCB1 Modulating Inflammatory Factors and the Role for Developing Major Depressive Disorder |
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| Unknown status | N/A | 350 | RoW | fish oil capsules, escitalopram | Shanghai Mental Health Center | Major Depressive Disorder | 12/21 | 12/21 | | |
NCT04069819: The Phosphodiesterase-3 Inhibitor Cilostazol as an Adjunctive to Antidepressants in Patients With Major Depressive Disorder. |
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| Completed | N/A | 80 | RoW | Cilostazol 50 MG Oral Tablet, Escitalopram, Placebo | Sadat City University | Major Depressive Disorder | 12/21 | 12/21 | | |
ChiCTR1900027636: A comparative study for the efficacy of group cognitive behavior therapy and SSRIs antidepressants in the treatment of depression patients with panic attack |
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| Not yet recruiting | N/A | 45 | | GCBT ;escitalopram ;GCBT+escitalopram | Peking University Sixth Hospital; Peking University Sixth Hospital, Beijing Municipal Commission of Science and Technology | Depression | | | | |
ChiCTR2100041741: Efficacy of transcranial direct current stimulation (tDCS) of treating depersonalization/derealization disorder |
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| Recruiting | N/A | 80 | | F3-FP2 ;TP4-left shoulder ;Duluoxetine and escitalopram placebo ;Escitalopram and Duluoxetine placebo | Beijing Anding Hospital, Capital Medical University; Beijing Anding Hospital, Capital Medical University, Qing Miao Programme Foundation for the Talents by Beijing Hosptitals Authority | Depersonalization/realization Disorder | | | | |
ChiCTR2100049747: Efficacy Observation and the Mechanism Analysis of Ningkun Jieyu Decoction in the Treatment of Major Depressive Disorder (Liver Depression and Heat) Based on the Intestinal Flora |
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| Not yet recruiting | N/A | 60 | | Granules of Ningkun Jieyu Decoction ;Escitalopram oxalate tablets (Bishike) | Xiyuan Hospital, China Academy of Chinese Medical Sciences; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Qihuang Project | Major Depressive Disorder | | | | |
NCT06325605: Efficacy and Safety of Bifidobacterium Combined With High-frequency Transcranial Magnetic Stimulation in the Treatment of Adolescent Depression |
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| Completed | N/A | 100 | RoW | Bifidobacterium, 0.07g/capsule, approval number: Guo Yao Zhun Zi S10950032, Shanghai Sine Pharmaceutical Co., Ltd., High-frequency rTMS, Escitalopram Oxalate, manufacturer: Sichuan Kelun Pharmaceutical Co., Ltd.; approval No.: Guo Yao Zhun Zi H20080788 | Zhen-Hong Hu | Adolescent Depression | 10/22 | 10/22 | | |
ChiCTR2000036976: The exploration of the treatment mode of electroacupuncture combined with SSRI drugs for different degrees of first-onset depression |
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| Not yet recruiting | N/A | 466 | | Electroacupuncture and Escitalopram ;Sham EA and Escitalopram ;Electroacupuncture and placebo drugs ;Sham EA and Escitalopram ;Sham EA and placebo drugs | Shanghai Municipal Hospital of Traditional Chinese Medicine; Shanghai Municipal Hospital of Traditional Chinese Medicine, Government grants | Depression | | | | |
