Rituxan (rituximab) / Roche |
Reditux1: A therapeutic and side effects’ comparison between Reditux and brand type (MabThera) in Diffuse Large B Cell Lymphoma (DLBCL) |
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| Completed | N/A | 30 | RestOfWorld | Reditux (rituximab biosimilar) | | Lymphoma | | | | |
ChiCTR-ONRC-14005106: HIGH DOSE RITUXIMAB IN COMBINATION WITH AUTOLOGOUS STEM-CELL TRANSPLANTATION (BEFORE AND AFTER) FOR RELAPSED AGGRESSIVE B-CELL NON-HODGKIN'S LYMPHOMAS. |
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| Completed | N/A | 40 | | autologous stem cell transplantation ;rituximab combined with autologous stem cell transplantation | The First Affiliated Hospital of Wenzhou Medical University; Level of the institution:, The First Affiliated Hospital of Wenzhou Medical University | B cell lymphoma | | | | |
NCT06190457: Safety and Efficacy of Intrathecal Rituximab in 16 Children of Stage Ⅲ、ⅣNon-Hodgkin Lymphoma |
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| Completed | N/A | 16 | NA | intrathecal rituximab | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Lymphoma, Non-Hodgkin, Child, Only | 12/20 | 08/22 | | |
NCT01357733: Interim FDG PET/CT in Diffuse Large B Cell Lymphoma (DLBCL) Patients |
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| Active, not recruiting | N/A | 53 | RoW | Early interim FDG PET/CT after 1 cycle of R-CHOP | The Catholic University of Korea | Lymphoma, Large B-Cell, Diffuse | 11/17 | 03/23 | | |
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ChiCTR1900024990: Comparative research on 99mTc-Rituximab and 99mTc-sulfur colloid in sentinel lymph node imaging of breast cancer |
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| Completed | N/A | | | | Shanxi Academy of medical sciences Shanxi Dayi Hospital; Shanxi Dayi Hospital, This study was supported by Shanxi province the fund project of natural science (No.2015011089 ) | breast cancer | | | | |
ChiCTR-INR-17010676: Radomized and controlled trial of therapeutic regimen of biological agents in refractory nephrotic syndrome |
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| Recruiting | N/A | 45 | | full dose prednisone+rituximab ;low dose prednisone+ribuximab ;prednisone+other anti-immune agents | Shanghai Jiaotong University School of Medicine Renji Hospital Nephrology; Shanghai Jiaotong University School of Medicine Renji Hospital Nephrology Department, Renji hospital and Shenkang company | refractory nephrotic syndrome | | | | |
ChiCTR-ICR-15007177: A Prospective Study on the Efficacy andSafety of Rituximab in Treatment for Neuromyelitis Optica associated Optic Neuritis |
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| Recruiting | N/A | 60 | | Intravenous 100mg Rituximab, 1/week*4 ;Oral azathioprine (2.5-3 mg/kg bodyweight/day) or mycophenolate mofetil (1000-1500mg/day) | The Ophthalmology Department of the Chinese Peoples Liberation Army Hospital; The Chinese Peoples Liberation Army Hospital, The National High Technology Research andDevelopment Program (No. 2015AA020511) | Neuromyelitis Optica associated Optic Neuritis | | | | |
ChiCTR1800016003: Clinical observation of the first-line treatment of diffuse large B cell lymphoma with Thalidomide combined or sequential R-CHOP |
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| Not yet recruiting | N/A | 80 | | Thalidomide+R-CHOP ;R-CHOP | The Second Affiliated Hospital of Dalian Medical University; The Second Affiliated Hospital of Dalian Medical University, no | lymphoma | | | | |
NCT06530004: Clinical Follow-up Study of Rituximab in the Treatment of Nephrotic Syndrome in Children |
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| Recruiting | N/A | 50 | RoW | Rituximab | The First Affiliated Hospital of Xiamen University | Nephrotic Syndrome, Rituximab, Children, Efficacy | 03/26 | 03/28 | | |
ChiCTR1800020382: Efficacy and safety of ultra-low dosage regimen of rituximab combined with corticosteroids in the treatment of pemphigus |
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| Recruiting | N/A | 42 | | Rituximab 500mg single infusion combined with routinedose of corticosteriods therapy ;Rituximab 100mg single infusion combined with routinedose of corticosteriods therapy ;Oral or intravenous infusion of routinedose of corticosteriods (prednisone or methylprednisolone) | West China Hospital, Sichuna University; West China Hospital, Sichuna University, the Scientific Research Staring Foundation for the Returned Overseas Chinese Scholars,Ministry of China | Pemphigus | | | | |
NCT02916316: Study Investigating the Cardiotoxicity of Anthracyclines in Patients With Diffuse Large B-Cell |
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| Active, not recruiting | N/A | 127 | Europe | R-CHOP with doxorubicin, R-CHOP with doxorubicin analogue, R-COMP | Fondazione Italiana Linfomi - ETS | Lymphoma, Large B-Cell, Diffuse Large B-Cell | 12/20 | 12/24 | | |
NCT04610242: Prediction of Rituximab Hypersensitivity and Desensitization Treatment |
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| Recruiting | N/A | 30 | RoW | skin test, desensitization for patients with positive skin test results | Peking Union Medical College Hospital | Drug Hypersensitivity Reaction | 12/20 | 12/20 | | |
ChiCTR1900022793: phase II clinical study for Lenalidomide in Combination with Intravenous Rituximab and methotrexate in patients with newly diagnosed primary CNS lymphoma |
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| Not yet recruiting | N/A | 102 | | Intravenous Rituximab and methotrexate plus Lenalidomide 25mg, qd, po, d1-10 ;Intravenous Rituximab and methotrexate | West China Hospital, Sichuan University; West China Hospital, Sichuan University, No | Primary central system B-cell lymphoma | | | | |
| Recruiting | N/A | 425 | Europe | History of exposure to anti-CD20 treatment since 01/01/2010, Completion of COVID19 vaccine at least 4 weeks ago | University Hospital Inselspital, Berne | COVID19 Vaccination, Rituximab, Immunosuppression | 08/21 | 10/21 | | |
ChiCTR1800016732: A prospective randomized controlled study using comprehensive geriatric assessment to guide treatment decisions in older patients with diffuse large b-cell lymphoma |
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| Not yet recruiting | N/A | 150 | | R-CHOP ;Support therapy | Beijing Hospital; Beijing Hospital, Beijing Committee of Science and Technology | diffuse large b-cell lymphoma | | | | |
HepB20, NCT04519710: Specific Anti-HBV Vaccine Response After Vaccination in Patients Requiring Anti-CD20 Monoclonal Antibodies |
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| Completed | N/A | 60 | Europe | o receive treatment with anti-CD20 (rituximab or ocrelizumab) and to be vaccinated against hepatitis B | Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida | HBV | 09/21 | 10/23 | | |
| Completed | N/A | 17478 | RoW | interferons, glatiramer acetate, teriflunomide, dimethyl fumarate, alemtuzumab, cladribine, fingolimod, ponesimod, rituximab, ocrelizumab, ofatumumab, natalizumab | IMPULS Endowment Fund | Multiple Sclerosis | 12/21 | 12/21 | | |
ChiCTR2000028715: A single arm study for doxorubicin hydrochloride liposome combined with lenalidomide, rituximab and dexamethasone in the treatment of elderly with diffuse large B-cell lymphoma |
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| Not yet recruiting | N/A | 30 | | doxorubicin hydrochloride liposome combined with lenalidomide, rituximab and dexamethasone | The Second Affiliated Hospital of Army Medical University; Xinqiao Hospital, National Nature Science Fund 81370594,National Nature Science Fund 81670100 | lymphoma | | | | |
ChiCTR2100043287: Study for therapeutic effect on intra-orbital low doses rituximab injection for thyroid-associated orbitopathy and idiopathic orbital inflammatory syndrome |
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| Recruiting | N/A | 100 | | rituximab 10mg ;rituximab 20mg ;rituximab 10mg ;rituximab 20mg | Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University; Tangdu Hospital, Fourth Military Medical University, self-raised | thyroid-associated orbitopathy and idiopathic orbital inflammatory syndrome | | | | |
ChiCTR2100042025: A multicenter randomized controlled clinical study of rituximab or in combination with human immunoglobulin in the treatment of severe pemphigus |
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| Recruiting | N/A | 40 | | RTX1000mg+IVIG+GC0.5-1mg/kg/d ;RTX500mg+IVIG+GC0.5-1mg/kg/d ;RTX500mg+GC0.5-1mg/kg/d ;Standard treatment plan | Dermatology Hospital of Southern Medical University; Dermatology Hospital of Southern Medical University, Self-raised | Pemphigus vulgaris/foliaceus | | | | |
ChiCTR1900024299: The first-line treatment of diffuse large B-cell lymphoma with sintilimab combined R-CHOP regimen: a single-arm, single-center clinical trial |
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| Recruiting | N/A | 40 | | sintilimab combined with R-CHOP regimen | The First Affiliated Hospital of Fujian Medical University; The First Affiliated Hospital of Fujian Medical University, Wu Jieping Medical Foundation | diffuse large B-cell lymphoma | | | | |
ChiCTR2100043079: Observational study of R2 chop (lenalidomide, rituximab, cyclophosphamide, doxorubicin, vindesine / vinorelbine and prednisone) in the first-line treatment of high-risk / high-risk DLBCL |
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| Recruiting | N/A | 100 | | Lenalidomide, 25mg, orally on day 1-14 | The First Affiliated Hospital of Kunming Medical University; The First Affiliated Hospital of Kunming Medical University, manufactor | DLBCL | | | | |
ChiCTR2000036239: A prospective clinical study of monoclonal antibody treatment for refractory thyroid-associated ophthalmopathy |
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| Recruiting | N/A | 80 | | glucocorticoid and rituximablucocorticoid and rituximab ;glucocorticoid | The Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine; The Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, The three-year action plan to promote the development of clinical skills and clinical innovation in major clinical research projects (2020-2022) | Thyroid-Associated Ophthalmopathy | | | | |
NCT04283747: Rituximab-Induced Hypogammaglobulinemia in Multiple Sclerosis |
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| Recruiting | N/A | 170 | RoW | Serum immunoglobulin titer | Mazandaran University of Medical Sciences | Multiple Sclerosis, Hypogammaglobulinemia | 10/22 | 12/22 | | |
NCT04640818: Safety and Efficacy of Cladribine Therapy After Anti CD20 Therapy |
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| Active, not recruiting | N/A | 45 | Europe | Cladribine Oral Tablet, Mavenclade, Rituximab, Mabthera, Rixathon, Ocrelizumab, Ocrevus | Claudio Gobbi, Merck AG Switzerland | Multiple Sclerosis | 10/22 | 10/22 | | |
NCT04435743: Efficacy and Safety of Lenalidomide With or Without Rituximab and Other Drugs in B-cell Non-Hodgkin's Lymphomas |
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| Recruiting | N/A | 1000 | RoW | Lenalidomide | Ruijin Hospital | Non-hodgkin Lymphoma,B Cell | 12/22 | 12/22 | | |
NCT05487703: A Study To Describe The Use Of Tofacitinib After Use Of Rituximab In Patients With Rheumatoid Arthritis In A Real-World Setting |
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| Completed | N/A | 1 | RoW | | Pfizer | Arthritis, Rheumatoid | 12/22 | 12/22 | | |
| Active, not recruiting | N/A | 3526 | Europe | Rituximab, Natalizumab, Fingolimod, Alemtuzumab, Interferon-beta, Glatiramer acetate, Dimethyl Fumarate | Karolinska Institutet, Patient-Centered Outcomes Research Institute, Kaiser Foundation Research Institute | Relapsing-remitting Multiple Sclerosis | 12/22 | 12/22 | | |
NCT04106830: Clinical and Imaging Patterns of Neuroinflammation Diseases in China (CLUE) |
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| Recruiting | N/A | 1000 | RoW | Intravenous steroid, Azathioprine, Mycophenolate Mofetil, Rituximab | Beijing Tiantan Hospital | NMO Spectrum Disorder, MRI, Multiple Sclerosis | 12/22 | 12/25 | | |
NCT04432402: Lenalidomide in Combination With R-GemOx in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma |
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| Recruiting | N/A | 124 | RoW | Lenalidomide, Rituximab, Gemcitabine, oxaliplatin | The First Affiliated Hospital with Nanjing Medical University | Diffuse Large B Cell Lymphoma | 12/22 | 12/24 | | |
ChiCTR2100053501: Dexamethasone, rituximab plus cyclosporine in the treatment of adults with primary immune thrombocytopenia |
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| Recruiting | N/A | 30 | | Combination therapy | The 967th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army ; The 967th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, self-financed | primary immune thrombocytopenia (ITP) | | | | |
ChiCTR2100042633: Single center, open and single arm clinical study on the safety and efficacy of r2-mtx-epoch regimen in the treatment of CD5 positive diffuse large B cell lymphoma |
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| Recruiting | N/A | 30 | | Rituximab combined with lenalidomide, etoposide, methotrexate, vincristine, adriamycin, cyclophosphamide, prednisone | The Affiliated Hospital of Xuzhou Medical University; The Affiliated Hospital of Xuzhou Medical University, Self-raised funds | DLBCL | | | | |
ChiCTR2200059158: Clinical study of Icariin soft capsules for prevention of neutropenia after chemotherapy for non-Hodgkin's lymphoma |
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| Not yet recruiting | N/A | 14 | | Icaritin + R-CHOP | He'nan Cancer Hospital; He'nan Cancer Hospital, Beijing Shenogen Biomedical Co., Ltd. | Neutropenia due to chemotherapy (CIN) | | | | |
ChiCTR2300069742: Clinical efficacy of low-dose rituximab combined with low-dose hormone in the treatment of mild to moderate refractory pemphigus: a prospective, single-center, randomized, parallel controlled trial |
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| Completed | N/A | 36 | | 200 mg Rituximab ;Immunosuppressants ;500 mg Rituximab | Dermatology Hospital of Southern Medical University, Guangzhou, China; Dermatology Hospital of Southern Medical University, Guangzhou, China, self-raised | pemphigus | | | | |
| Recruiting | N/A | 36 | Europe | Ibrutinib | IRCCS San Raffaele | PCNSL | 01/23 | 08/23 | | |
ChiCTR2100045959: Prospective study on the efficacy and safety of rituximab therapy for nephropathy syndrome |
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| Recruiting | N/A | 60 | | rituximab 0.6g-1.1g ;rituximab 0.4g | China-Japan Friendship Hospital; China-Japan Friendship Hospital, China-Japan Friendship Hospital | nephropathy syndrome | | | | |
ChiCTR2300072606: Comparative analysis of the efficacy of diferent doses of rituximab in the treatment of glomerular diseases: a retrospective clinical study |
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| Completed | N/A | 235 | | None ;None | Department of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China; West China School of Medicine and West China Hospital, Sichuan university, The research does not involve funding source | primary glomerular diseases | | | | |
APOLLO, ISRCTN11542980: Evaluating alternative treatment regimens for patients who have diffuse large B-cell lymphoma that is unsuitable for standard treatment |
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| No Longer Available | N/A | 56 | United Kingdom, England, Scotland | Polivy (polatuzumab vedotin-piiq) - Roche | Clatterbridge Cancer Centre NHS Foundation Trust, Roche;Hoffman-La Roche | Diffuse large B-cell lymphoma | | | | |
NCT05821192: Chemotherapy Plus PD-1 Monoclonal Antibody in the Treatment of Refractory or Relapsed Peripheral T-cell Lymphoma. |
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| Recruiting | N/A | 34 | RoW | Rituximab, Gemcitabine, Dexamethasone, Cisplatin, PD-1 monoclonal antibody | Ou Bai, MD/PHD, Second Hospital of Jilin University, China-Japan Union Hospital, Jilin University | Peripheral T-Cell Lymphoma, Not Otherwise Specified, Angioimmunoblastic T-cell Lymphoma | 04/23 | 12/24 | | |
FRILLY, NCT05840289: A Study on Fractionated Rituximab to Avoid Lysis Syndrome in Aggressive B-Lymphoma |
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| Active, not recruiting | N/A | 94 | Europe | fractionated first dose rituximab | University Hospital, Geneva | Aggressive B-Cell Non-Hodgkin Lymphoma | 05/23 | 05/23 | | |
ChiCTR2200066662: Analysis of transcript expression and immune infiltration before and after rituximab treatment in severe pemphigus vulgaris |
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| Recruiting | N/A | 30 | | None; None; None | Dermatology Hospital of Southern Medical University; Dermatology Hospital of Southern Medical University, Self-raised | pemphigus | | | | |
NCT06362044: A Study to Assess Frequency of Undetectable Minimal Residual Disease (uMRD) in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Venetoclax Tablets ± Intravenously (IV) Infused Rituximab in Routine Clinical Practice in Japan |
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| Recruiting | N/A | 89 | Japan | | AbbVie | Chronic Lymphocytic Leukemia | 12/24 | 12/24 | | |
ChiCTR2000034319: The stratified treament of diffuse large B cell lymphoma in elderly and very elderly patients, a prospective, multi-center, group control study |
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| Recruiting | N/A | 120 | | RCHOP ;R-miniCHOP ;R2 ;R2 | Chinese Academy of Medical Science & Peking Union Medical College; Peking Union Medical College, Unit self financing | diffuse large B cell lymphoma | | | | |
NCT05667909: Prognostic Model of Rituximab in the Treatment of MN |
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| Not yet recruiting | N/A | 50 | NA | Rituximab | Qianfoshan Hospital | Idiopathic Membranous Nephropathy | 07/23 | 12/23 | | |
NCT05777369: R-CMOP in Patients With Primary Diffuse Large B-cell Lymphoma |
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| Not yet recruiting | N/A | 30 | NA | Rituximab, Mitoxantrone hydrochloride liposome, Cyclophosphamide, Vincristine/Vindesine, Prednisone | The First Affiliated Hospital with Nanjing Medical University | Diffuse Large B-cell Lymphoma | 08/23 | 08/24 | | |
ChiCTR2000035956: Clinical study on desensitization treatment of asparaginase allergy |
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| Not yet recruiting | N/A | 15 | | Rituximab+Bortezomi | Shanghai Children's Medical Center; Shanghai Children's Medical Center, Shanghai Children's Medical Center | Acute lymphocytic leukemia | | | | |
| Recruiting | N/A | 30 | RoW | zanubrutinib 160 mg BID orally, rituximab: 375 mg/m2 intravenously on day 7, methotrexate: 3-3.5 g/m2 intravenously on day 1, temozolomide 100 mg on days 1-5 | Huai'an First People's Hospital, Affiliated Hospital of Nantong University, The First People's Hospital of Changzhou, The Affiliated Hospital of Xuzhou Medical University, Northern Jiangsu People's Hospital | Primary Central Nervous System Lymphoma | 04/26 | 04/26 | | |
ChiCTR2100050786: The study of the efficacy and safety of zebutinib, rituximab, methotrexate and lenalidomide in the treatment of relapsed and refractory primary B-cell lymphoma of central nervous system |
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| Recruiting | N/A | 30 | | zebutinib, rituximab, methotrexate and lenalidomide | The Affiliated Hospital of Xuzhou Medical University; The Affiliated Hospital of Xuzhou Medical University, Self-raised funds | B cell lymphoma | | | | |
NCT05532111: Efficacy and Safety of the Treatment of Primary Membranous Nephropathy: A Randomized Clinical Trial |
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| Not yet recruiting | N/A | 60 | NA | Rituximab combined with tacrolimus induction + rituximab maintenance, Rituximab combined with tacrolimus induction + tacrolimus maintenance, Glucocorticoid combined with cyclophosphamide induction + maintenance | RenJi Hospital | Efficacy and Safety | 09/23 | 09/24 | | |
ELECTRIC, NCT05555979: A Study to Assess Change in Patient Experience in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Venetoclax Tablets + Intravenous Rituximab or Bruton's Tyrosine Kinase Inhibitors Tablets in the United Kingdom |
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| Completed | N/A | 100 | Europe | | AbbVie | Chronic Lymphocytic Leukemia | 04/24 | 04/24 | | |
NCT06245707: the Effects of Different Treatment Schemes on Cognitive Function of Patients With Idiopathic Membranous Nephropathy |
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| Recruiting | N/A | 2 | RoW | prednisone,methylprednisone and cyclophosphamide, Rituximab | Beijing Friendship Hospital | Mild Cognitive Impairment, Idiopathic Membranous Nephropathy | 09/25 | 09/25 | | |
ChiCTR2100052168: Effect of combination of Rituximab and chemoradiotherapy on survival of adult patients with high-grade Glioma after operation |
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| Not yet recruiting | N/A | 92 | | Combined Chemotherapy and radiotherapy with Nituzumab ;No | Beijing Huaxin Hospital; Beijing Huaxin Hospital, Baitai bio-pharmaceutical Co. , Ltd. | Glioma | | | | |
| Not yet recruiting | N/A | 12 | Europe | Measure of the circulating tumor DNA | Centre Henri Becquerel | Diffuse Large B Cell Lymphoma | 11/24 | 05/25 | | |
| Not yet recruiting | N/A | 100 | NA | Surgery combinate with Endocrine therapy, Endocrine therapy | The Third Xiangya Hospital of Central South University | Advanced Prostate Cancer, Lower Urinary Tract Symptoms, Quality of Life, Overall Survival, Progression of Prostate Cancer | 11/23 | 11/25 | | |
NCT03791827: Multicenter Registry of Pediatric Lupus Nephritis in China |
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| Recruiting | N/A | 1200 | RoW | Corticosteroid, Steroid, Prednisone, Methylprednisone, Prednisolone, Hydroxychloroquine, Cyclophosphamide, Mycophenolate Mofetil, Azathioprine, Tacrolimus, Cyclosporine A, Rituximab, anti-CD20 antibody | Xiqiang Dang, The Children's Hospital Affiliated to Suzhou University, Shandong Provincial Hospital, Guizhou Provincial People's Hospital, LanZhou University, The First Affiliated Hospital of Inner Mongolia Medical College, People's Hospital of Zhangjiajie, Puyang Oilfield General Hospital, The First Affiliated Hospital of Anhui Medical University, Guizhou Maternal and Child Health Care Hospital, The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Shenzhen Children's Hospital, The Second Affiliated Hospital of Harbin Medical University, Yichang Central People's Hospital, Xian Children's Hospital, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science & Technology, The First People's Hospital of Yunnan, The First Affiliated Hospital of Xiamen University, The First Affiliated Hospital of Xinxiang Medical College, Shanxi Provincial Maternity and Children's Hospital, Liaocheng People's Hospital, Fujian Provincial Hospital, First Affiliated Hospital of Guangxi Medical University, Second Hospital of Lanzhou University, Guangzhou First People's Hospital, The Second Hospital of Shandong University, Children's Hospital of Hebei Province, Beijing Children's Hospital, Zhengzhou Children's Hospital, The Children's Hospital of Chongqing Medical University, Wuxi Children's Hospital, The Children's Hospital of Fudan University, Shanghai Children's Medical Center, Qilu Children's Hospital of Shandong University | Lupus Nephritis, Children, Steroid, Immunosuppressive Treatment | 11/23 | 11/24 | | |
NCT05782933: Efficacy of Rituximab Combined With Cyclosporine in the Treatment of Idiopathic Membranous Nephropathy |
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| Recruiting | N/A | 2 | RoW | Rituximab, Modified Ponticelli regimen | Beijing Friendship Hospital | Idiopathic Membranous Nephropathy | 12/23 | 12/23 | | |
ChiCTR1800016662: A prospective study of the diagnosis and treatment for children with autoimmune encephalitis. |
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| Recruiting | N/A | 50 | | First line: Intravenous immunoglobulin and ocorticoid treatment; second line: depends on the Rankins score and by Rituximab or cyclic lindamides, or Mycophenolate or azathioprine | Children's Hospital of Chongqing Medical University; Children's Hospital of Chongqing Medical University, Chongqing Science and Techology Commission,and Children's Hospital of Chongqing Medical University | Autoimmune encephalitis | | | | |
ChiCTR2000038097: Characteristics of intestinal flora of lymphoma and intervention of traditional Chinese Medicine |
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| Recruiting | N/A | 100 | | chinese medical+R-CHOP ;R -CHOP | The First Affiliated Hospital of Zhejiang Chinese Medical University; Zhejiang Provincial Hospital of Chinese Medicine, Special project for the modernization of traditional Chinese medicine in zhejiang province(No.2020ZX007) | non-Hodgkin's lymphoma | | | | |
ChiCTR2200066961: An exploratory clinical study of Selinexor combined with zanubrutinib and Rituximab in the treatment of relapsed/refractory senile DLBCL |
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| Recruiting | N/A | 30 | | Selinexor+zanubrutinib+Rituximab | The Third People's Hospital of Fujian Province; The Third People's Hospital of Fujian Province, Antengene Corporation Limited | Diffuse Large B-cell Lymphoma | | | | |
NCT05784987: R-MINE+X in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma |
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| Not yet recruiting | N/A | 60 | NA | Rituximab, Mitoxantrone hydrochloride liposome, Isophosphamide, Etoposide, X: Orelabrutinib, X: Chidamide, X: Penpulimab, X: Lenalidomide | The First Affiliated Hospital with Nanjing Medical University | Diffuse Large B-cell Lymphoma | 01/24 | 01/25 | | |
NCT06190301: RCT on Intralesional Rituximab Injection Versus ISRT in Ocular Adnexal MALT Lymphoma |
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| Recruiting | N/A | 108 | RoW | Rituximab, Involved Site Radiation Therapy | Zhongshan Ophthalmic Center, Sun Yat-sen University | Primary Ocular Adnexal MALT Lymphoma | 12/27 | 12/27 | | |
NCT01829958: Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy |
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| Active, not recruiting | N/A | 201 | US | rituximab, prednisone, Geriatric Assessment | Memorial Sloan Kettering Cancer Center | Non Hodgkin Lymphoma (NHL), Diffuse Large B-cell Lymphoma (DLBCL) | 04/25 | 04/25 | | |
NCT03737136: Comparison Between Bortezomib and Rituximab Plus Plasmapheresis in AMR |
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| Recruiting | N/A | 20 | RoW | Bortezomib, Velcade | Shahid Beheshti University of Medical Sciences | Antibody-mediated Rejection | 05/24 | 10/25 | | |
ChiCTR2100049205: A prospective randomized controlled multicenter clinical study on the treatment strategy of primary membranous nephropathy in the high-risk phase |
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| Recruiting | N/A | 90 | | Cyclophosphamide combined with glucocorticoids ;Low-dose Cyclophosphamide, glucocorticoid combined with rituximab ;Rituximab | Shanghai Dongfang Hospital; Shanghai Dongfang Hospital, Pudong New Area Joint Public Relations Project | Membranous nephropathy | | | | |
NCT06478472: Prospective Clinical Study of Orelabrutinib in Combination With Rituximab (OR) for Primary Marginal Zone Lymphoma (MZL) That Failed or Not Suitable for Local Therapy |
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| Recruiting | N/A | 36 | RoW | Orelabrutinib in combination with rituximab | The First Affiliated Hospital of Xiamen University, The First Hospital of Jilin University, Fujian Cancer Hospital, Guangdong Provincial People's Hospital, Nanfang Hospital, Southern Medical University, The Second Affiliated Hospital of Dalian Medical University, Jiangxi Provincial Cancer Hospital, Wuhan Union Hospital, China, Shanxi Provincial Cancer Hospital, Chinese PLA General Hospital | Marginal Zone Lymphoma | 06/27 | 06/27 | | |
NCT06068829: Inebilizumab and Rituximab in Neuromyelitis Optica Spectrum Disorders |
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| Not yet recruiting | N/A | 80 | NA | Inebilizumab, Rituximab(RTX) | Feng Jinzhou | Neuromyelitis Optica Spectrum Disorders | 06/24 | 06/25 | | |
NCT03798860: Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation |
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| Recruiting | N/A | 70 | Europe | blood samples | Hannover Medical School | Lung Transplantation, Donor-specific Anti-human Leukocyte Antigen(HLA) Antibodies | 07/24 | 12/24 | | |
ChiCTR2200058170: Clinical study of small-dose trimethoprim-sulfamethoxazole prevents pneumocystis pneumonia in B-cell lymphoma patients receiving chemotherapy. |
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| Not yet recruiting | N/A | 260 | | R-CHOP/R-CDOP regimen (Rituximab, Cyclophosphamide, Hydroxyldaunorubicin/Liposome doxorubicin, Oncovin, Prednisone) ;R-CHOP/R-CDOP (Rituximab, Cyclophosphamide, Hydroxyldaunorubicin/Liposome doxorubicin, Oncovin, Prednisone) Prophylactic treatment with SMZ | The First Affiliated Hospital, Zhejiang University College of Medicine; The First Affiliated Hospital, Zhejiang University College of Medicine, Self-faised funds | B cell lymphoma | | | | |
NCT05990985: The Efficacy and Safety of the RCMOP Sequential Therapy as a First-line Treatment for Patients With Intermediate-to-high Risk Diffuse Large B-cell Lymphoma Who Had Incomplete Remission. |
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| Not yet recruiting | N/A | 20 | RoW | Mitoxantrone hydrochloride liposome injection, duoenda, RiTUXimab Injection, lituoxidankang, Cyclophosphamid, huanlinxianan, Vincristine, changchunxinjian, Prednisolone, ponisong | The First Hospital of Jilin University, CSPC Ouyi Pharmaceutical Co., Ltd. | Diffuse Large B-cell Lymphoma | 08/24 | 08/26 | | |
NCT05679336: Rituximab, Cyclophosphamide, and Corticosteroids in Primary Membranous Nephropathy |
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| Recruiting | N/A | 40 | RoW | Rituximab, Cyclophosphamide, and Corticosteroids | St. Petersburg State Pavlov Medical University | Membranous Nephropathy - PLA2R Induced | 08/24 | 08/24 | | |
ChiCTR2100050205: Prediction of therapeutic effect and prognosis of different treatment schemes for idiopathic membranous nephropathy by intestinal flora |
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| Not yet recruiting | N/A | 180 | | Nil ;Symptomatic treatment ;Hormone+Tacrolimus ;Hormone+Cyclophosphamide ;Hormone+Mycophenolate mofetil ester ;Rituximab | The First Affiliated Hospital of Shandong First Medical University&Shandong Provincial Qianfoshan Hospital; The First Affiliated Hospital of Shandong First Medical University&Shandong Provincial Qianfoshan Hospital, raise independently | Idiopathic membranous nephropathy | | | | |
| Not yet recruiting | N/A | 500 | Europe | | Mario Negri Institute for Pharmacological Research | Membranous Nephropathy | 09/29 | 09/29 | | |
ChiCTR2200057174: Efficacy and safety of glutamine combined with Clostridium butyricum in the treatment of hormone-dependent minor lesion nephropathy |
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| Not yet recruiting | N/A | 98 | | Conventional therapy (steroid+rituximab) ;Conventional treatment + glutamine + clostridium butyric acid | Shanghai Children's Hospital; Shanghai Children's Hospital, Shanghai Science and Technology Committee | Primary nephrotic syndrome | | | | |
ChiCTR2200064268: Single center randomized controlled study of rituximab combined with low-dose steroids or tacrolimus in the treatment of primary membranous nephropathy |
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| Not yet recruiting | N/A | 100 | | rituximab +steroids ;rituximab + tacrolimus | Xijing Hospital; Xijing Hospital, National Natural Science Foundation of China (81770764). | primary membranous nephropathy | | | | |
ChiCTR2200063564: Efficacy and safety of Cotrimoxazole in the prevention of rituximab in glomerulonephritis: a multicenter randomized controlled study |
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| Not yet recruiting | N/A | 110 | | Cotrimoxazole treatment ;observation | Xijing Hospital; Xijing Hospital, National Natural Science Foundation of China (81770764) | glomerulonephritis | | | | |
ChiCTR2100051829: Rituximab combined with plasma infusion in the treatment of relapsed and refractory thrombotic thrombocytopenic purpura |
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| Not yet recruiting | N/A | 40 | | Rituximab combined with plasma infusion | The Second Affiliated Hospital of Kunming Medical University; The Second Affiliated Hospital of Kunming Medical University, subject | thrombotic thrombocytopenic purpura | | | | |
NCT05761938: A Study of Rituximab in Frontline Therapy for Glomerulonephritis |
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| Recruiting | N/A | 100 | RoW | | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Glomerulonephritis | 12/24 | 12/25 | | |
| Recruiting | N/A | 10000 | RoW | Biologic or targeted synthetic DMARD, etanercept, adalimumab, infliximab, golimumab, tocilizumab, abatacept, rituximab, ustekinumab, secukinumab, ixekizumab, or biosimilars, tofacitinib, baricitinib, upadacitinib | Seoul National University Hospital | Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis | 12/29 | 06/30 | | |
ChiCTR2200057381: Efficacy and safety of low-dose rituximab in the treatment of membranous nephropathy |
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| Not yet recruiting | N/A | 203 | | rituximab ;hormone combined with cyclophosphamide | Peking University Third Hospital; Peking University Third Hospital, Peking University third Hostipal | membranous nephropathy | | | | |
ChiCTR2200063389: Efficacy and Safety of Rituximab Combined With Tacrolimus in the Treatment of Intermediate-to-high Risk Primary Membranous Nephropathy: A Randomized Clinical Trial |
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| Recruiting | N/A | 60 | | Rituximab combined with tacrolimus induction + rituximab maintenance ;Rituximab combined with tacrolimus induction + tacrolimus maintenance ;Glucocorticoid combined with cyclophosphamide induction + maintenance | Renji Hospital Affiliated to Shanghai jiao tong university school of medicine; Renji Hospital Affiliated to Shanghai jiao tong university school of medicine, None | Primary Membranous Nephropathy | | | | |
ChiCTR2200066211: Clinical study of obrutinib, lenalidomide combined with rituximab in the treatment of relapsed/refractory diffuse large B-cell lymphoma in elderly patients based on comprehensive geriatric assessment system |
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| Not yet recruiting | N/A | 30 | | Obrutinib, lenalidomide and rituximab were given | Beijing Hospital; Beijing Hospital, National High Level Hospital Clinical Research funding | Diffuse large B-cell lymphoma | | | | |
| Not yet recruiting | N/A | 180 | | RCHOP+X; RCHOP | The First Affiliated Hospital of Zhejiang University Medical College; The First Affiliated Hospital of Zhejiang University Medical College, raise independently | Diffuse large B-cell Lymphoma | | | | |
ChiCTR2400082178: A cohort study of proteinuria selectivity index predicting the efficacy of rituximab in the treatment of primary nephrotic syndrome |
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| Recruiting | N/A | 36 | | None; None | Shenzhen Second People’s Hospital; Shenzhen Second People’s Hospital, Shenzhen Key Medical Discipline Construction Fund (SZXK009) and Shenzhen medical and health three project(SZSM202211013). | Primary nephrotic syndrome | | | | |
ChiCTR2200057712: Epigenetic-guided clinical trial of sidarbenamine combined with R-CHOP in the initial treatment of B-cell lymphoma |
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| Recruiting | N/A | 92 | | Chidamide Combined with R-CHOP Regimen | Peking University Third Hospital; Peking University Third Hospital, self-funded | lymphoma | | | | |
ChiCTR2200064434: Efficacy of rituximab in the treatment of adult minimal change disease - a multicenter two-way cohort study |
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| Not yet recruiting | N/A | 92 | | Rituximab ;Conventional treatment | The Second People's Hospital of Shenzhen; The Second People's Hospital of Shenzhen, Clinical Research Fund of the Second People's Hospital of Shenzhen | minimal change disease (MCD) | | | | |
ChiCTR2000034214: A multicenter, prospective, cohort study for the efficacy and adverse reactions of ANCA associated glomerulonephritis based on ARRS score |
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| Not yet recruiting | N/A | 106 | | Induction remission stage: Glucocorticoid + cyclophosphamide; Maintain remission stage: Hormone + azathioprine / methotrexate / mycophenolate mofetil ;Induction remission stage: Methylprednisolone + intravenous cyclophosphamide or rituximab; Maintain remission stage: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + cyclophosphamide + rituximab + plasma exchange; Maintain: Hormone + azathioprine / mycophenolate mofetil / rituximab ;Induction: Methylprednisolone + intravenous cyclophosphamide; Maintain: Hormone + azathioprine / methotrexate / mycophenolate mofetil | Children's Hospital Affiliated to Chongqing Medical University; Children's Hospital Affiliated to Chongqing Medical University, self-financing | ANCA associated glomerulonephritis | | | | |
NCT05923879: Mechanism Investigation of Selinexor Combined With Lenalidomide and Rituximab in the Treatment of Diffuse Large B-cell Lymphoma |
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| Not yet recruiting | N/A | 30 | RoW | Selinexor combined with lenalidomide and rituximab | Ruijin Hospital | Lymphoma, Large B-Cell, Diffuse | 06/25 | 06/25 | | |
NCT05809180: Pro-miniCHOP-like Regimen for Treatment-naive Elderly Patients |
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| Recruiting | N/A | 35 | RoW | Rituximab, MabThera, Orelabrutinib, Yinuokai, Pomalidomide, Anyve, Pro-miniCHOP-like regimen, R-miniCHOP-like regimen | The First Affiliated Hospital of Soochow University | Diffuse Large B Cell Lymphoma | 07/25 | 07/26 | | |
ChiCTR2200061828: Multicenter clinical trial of bortezomib combined with rituximab as second-line treatment for children with immune thrombocytopenia |
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| Not yet recruiting | N/A | 80 | | Bortezomib combined with rituximab; rituximab | Fujian Children's Hospital; Fujian Children's Hospital, self-funded | immune thrombocytopenia | | | | |
| Recruiting | N/A | 900 | US | Natalizumab, Alemtuzumab, Ocrelizumab, Rituximab, Cladribine, Ofatumumab, Ublituximab-xiiy, Tysabri, Lemtrada, Ocrevus, Rituxan, Mavenclad, Kesimpta, Briumvi, Glatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod, Copaxone, Glatopa, Avonex, Betaseron, Extavia, Rebif, Plegridy, Aubagio, Tecfidera, Vumerity, Bafiertam, Gilenya, Mayzent, Zeposia, Ponvory, Tascenso | Johns Hopkins University, Patient-Centered Outcomes Research Institute, National Multiple Sclerosis Society | Multiple Sclerosis, Relapsing-Remitting | 08/25 | 08/25 | | |
ChiCTR2000039342: A clinical trial for zanubrutinib combined with rituximab as a treatment for older patients with diffuse large B-cell lymphoma based on Comprehensive Geriatric Assessment |
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| Recruiting | N/A | 39 | | zanubrutinib combined with rituximab | Beijing Hospital; Beijing Hospital, self funding | diffuse large B cell lymphoma | | | | |
| Active, not recruiting | N/A | 60 | Europe | Patient with histologically confirmed diffuse large B-cell lymphoma with a planned first line treatment by R-CHOP. | Institut Claudius Regaud, AstraZeneca | Diffuse Large B-cell Lymphoma | 10/25 | 10/25 | | |
ChiCTR2200058984: Study on the dose-effect relationship of rituximab in patients with myasthenia gravis and the treatment differences of different doses based on population pharmacokinetic/pharmacodynamic model |
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| Not yet recruiting | N/A | 135 | | Rituximab 400mg, once a week for 4 weeks ;100mg, once a week, for 4 consecutive weeks or 100mg + 500mg single treatment | Beijing Hospital; Beijing Hospital, Beijing Hospital Clinical Research 121 Project | myasthenia gravis | | | | |
ChiCTR2300067726: Stratified Therapy on Pediatric AAGN Based on Risk Assessment: A Prospective, Multicenter, Open, Tendentious Matched Control Clinical Study |
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| Not yet recruiting | N/A | 400 | | Glucocorticoid + 4 doses of rituximab + 2 times of intravenous cyclophosphamide pulse therapy ;Glucocorticoid + 4 doses of rituximab | Children's Hospital Affiliated to Chongqing Medical University; Children's Hospital Affiliated to Chongqing Medical University, National Key R&D Program of China (Grant Number: 2021YFC2702002) | ANCA associated glomerulonephritis | | | | |
ChiCTR2400079432: Telitacicept Exploratory study of sequential rituximab in the treatment of Sjogren's syndrome with severe thrombocytopenia |
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| Not yet recruiting | N/A | 12 | | Using Telitacicept | the First People's Hospital of qinzhou; the First People's Hospital of qinzhou, raise independently | Sjogren's syndrome combined with severe thrombocytopenia | | | | |
ChiCTR2400087592: Study on the efficacy, safety, new evaluation methods and application of molecular prognostic models of MEDZ-R regimen in the treatment of primary central nervous system large B-cell lymphoma under the guidance of precision medicine |
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| Recruiting | N/A | 43 | | MEDZ-R regimen (rituximab 375 mg/m2 d0 + methotrexate 3.5 g/m2 d1 (infused for 3 hours, 12 times of rescue with calcium folinate 100 mgq6h starting from the 24th hour of MTX infusion) + liposomal doxorubicin 30 mg/m2 d3 + etoposide 60 mg/m2 d3-5 + zanubrutinib 160 mg bid starting from d3 (stop on d1-2 of each cycle) q3w) | West China Hospital, Sichuan University; West China Hospital, Sichuan University, China Zhongguancun Precision Medical Science and Technology Foundation | primary central nervous system large B-cell lymphoma | | | | |
ChiCTR2400081694: Exploratory study on the predictive value of 89Zr-rituximab immune PET for the efficacy and prognosis of PTLD |
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| Not yet recruiting | N/A | 20 | | Complete 89Zr-rituximab immune PET before treating PTLD. | Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine; Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine, self-raised | posttransplant lymphoproliferative disorder | | | | |
ChiCTR2300076737: A randomized controlled study of rituximab in combination with short-term corticosteroids or tacrolimus for primary membranous nephropathy |
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| Not yet recruiting | N/A | 204 | | Prednisone acetate+rituximab; Tacrolimus+rituximab; rituximab | The Second Affiliated Hospital of Nanchang University; The Second Affiliated Hospital of Nanchang University, The Second Affiliated Hospital of Nanchang University Funding Program | primary membranous nephropathy | | | | |
ChiCTR2400084808: A cohort study of rituximab versus tacrolimus in the treatment of idiopathic membranous nephropathy |
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| Not yet recruiting | N/A | 40 | | rituximab; tacrolimus | The Seventh Affiliated Hospital Sun Yat-sen University; The?Seventh?Affiliated?Hospital?Sun?Yat-sen?University, The Seventh Affiliated Hospital, Sun Yat-sen University Clinical Research 735 Program | Idiopathic membranous nephropathy (IMN) is the most common pathological type of primary nephrotic syndrome in adults, characterised by subepithelial in situ immune complex deposition, complement activation, structural disorders of the podocyte, and functional impairment of the glomerular filtration barrier. | | | | |
ChiCTR2200057914: A prospective, multicenter clinical study of PET/CT and IPI adapted treatment for newly diagnosed diffuse large B-cell lymphoma patients |
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| Recruiting | N/A | 160 | | 6*R-CHOP ;6*R-CHOP + 2*R ;6*R-CHOP + 2*R, 6*Obutinib ;8*R-CHOP, 6*Obutinib | The First Affiliated Hospital of Medical College, Zhejiang University; The First Affiliated Hospital of Medical College, Zhejiang University, self-raised | Diffuse large B-cell lymphoma | | | | |