CNS Disorders  >>  bupropion sustained-release  >>  Phase 4
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16 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
bupropion sustained-release / Generic mfg.
NCT01012024: Efficacy of Bupropion for ADHD in Adults

Completed
4
32
US
Bupropion Sustained Release (SR), Wellbutrin SR
National Institute on Drug Abuse (NIDA)
Attention-Deficit/Hyperactivity Disorder, Substance Use Disorders
08/01
08/01
NCT00307203: Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke

Completed
4
51
US
bupropion SR, Zyban, Wellbutrin, Cognitive Behavioral Group Therapy, CBT, nicotine replacement therapy, nicotine patch; nicotine gum
National Institute on Drug Abuse (NIDA)
Tobacco-Use Disorder, Schizophrenia, Psychotic Disorders
02/04
02/04
NCT00181896: Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder

Terminated
4
1
US
bupropion SR
Massachusetts General Hospital
Depression, Bipolar Disorder
02/07
 
NCT01576640: Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia

Terminated
4
17
US
NRT, Bupropion SR 150mg bid, Relapse Prevention-Oriented Cognitive Behavioral Therapy
Massachusetts General Hospital
Nicotine Dependence, Schizophrenia
10/07
10/07
NCT00511134: Study of Lunesta Versus Placebo for Sleep Problems Related to Smoking Cessation and Zyban

Terminated
4
4
US
Eszopiclone, Lunesta, Bupropion, Zyban
Yale University, Sunovion
Insomnia, Nicotine Dependence
12/08
12/08
NCT00132821: Impact of Smoking Cessation on Sleep - 5

Completed
4
59
US
Bupropion, Zyban, Transdermal Nicotine Patch, Placebo Bupropion, Placebo transdermal nicotine patch
National Institute on Drug Abuse (NIDA)
Tobacco Use Cessation, Sleep Disorders
05/09
05/09
CO-MED, NCT00590863: Combining Medications to Enhance Depression Outcomes

Completed
4
665
US
SSRI + placebo, escitalopram, placebo, Escitalopram + Bupropion SR, bupropion-SR, Venlafaxine XR + Mirtazapine, venlafaxine-XR, mirtazapine
National Institute of Mental Health (NIMH)
Major Depressive Disorder
09/09
09/09
NCT01574703 / 2011-005513-37: Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.

Completed
4
4595
US, Canada, Europe, RoW
placebo, varenicline tartrate, Chantix; Champix, bupropion hydrochloride, Zyban, Nicotine Replacement Therapy Patch, NRT
Pfizer
Smoking Cessation
07/15
07/15
STOP, NCT01015170: Study: Effectiveness of Zyban in a Clinical Population

Completed
4
454
Canada
bupropion HCl, Zyban
Centre for Addiction and Mental Health, Ontario Ministry of Health and Long Term Care
Cigarette Smoking, Nicotine Addiction, Smoking Cessation
10/15
10/15
NCT02162862: Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease

Completed
4
99
US
Behavioral Counseling, bupropion-SR, Wellbutrin
Eva Szigethy, Crohn's and Colitis Foundation
Sleep Disturbance, Fatigue, Inflammatory Bowel Disease
06/16
06/16
NCT02238977: Bupropion for Depression in ESRD Patients on Hemodialysis

Terminated
4
1
US
Fluoxetine, Prozac, Bupropion, Wellbutrin SR
University of Arkansas, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Major Depression, End Stage Renal Disease
03/18
03/18
NCT03126682: Effect of Bupropion on Seizure Threshold in Depressed Patients

Completed
4
10
US
Wellbutrin SR 300Mg Extended-Release Tablet, Bupropion sustained release formulation
Duke University
MDD
05/18
05/18
NCT02420015: Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia

Completed
4
35
US
Nicotine replacement therapy, nicotine gum, patch, inhaler, and/or lozenge, Bupropion, Zyban, cognitive-behavioral smoking cessation counseling, Mobile Contingency Management, mCM, Stay Quit Coach, SMS text messaging, texting
Duke University
Schizophrenia, Cigarette Smoking
01/19
01/19
CPT-SMART, NCT03978442: for Treatment of PTSD and Cigarette Smoking

Recruiting
4
120
US
Smoking Cessation Cognitive Behavioral Therapy (CBT), CBT, Bupropion, Zyban, Cognitive Processing Therapy, CPT, Smoking Abstinence Reinforcement Therapy, SMART, Yoked Contingency Management, Control CM
VA Office of Research and Development
Smoking, Stress Disorders, Post-Traumatic
09/24
09/24
NCT03950427: PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

Recruiting
4
120
US
Videogame-based physical activity, sedentary videogame, Bupropion, Wellbutrin, Zyban, Counseling
University of California, San Francisco, Tobacco Related Disease Research Program
Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
07/25
07/25
NCT05737511: Efficacy of Hydroxyzine for Patients With Panic Disorder

Not yet recruiting
4
80
NA
Hydroxyzine, Atarax, Vistaril, Escitalopram Oxalate, citalopram, fluoxetine, fluvoxamine, paroxetine, paroxetine CR, sertraline, venlafaxine XR,, Alprazolam, clomipramine, clonazepam, diazepam, imipramine, lorazepam, mirtazapine, reboxetine, Bupropion SR, divalproex, duloxetine, gabapentin, levetiracetam, milnacipran, moclobemide, olanzapine, phenelzine, quetiapine, risperidone, tranylcypromine
Sultan Qaboos University
Panic Disorder
12/26
12/26

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