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203 Trials

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oxaliplatin / Generic mfg.
ChiCTR-TRC-12002393: Preoperative Concurrent Chemoradiotherapy for Potentially Resectable Adenocarcinoma of the Esophagogastric Junction

Completed
N/A
450
 
preoperative radiochemotherapy+surgeron+adjuvantchemotherapy ;surgeron+adjuvant chemotherapy
Hebei Medical University affiliated Fourth Hospital; Level of the institution:, self-raise
Adenocarcinoma of the Esophagogastric Junction
 
 
ChiCTR-IPR-14005415: Phase II Randomised Control Study of Neoadjuvant Docetaxel/Oxaliplatin/Xelode (DOX) in Locally Advanced Gastric Cancer

Recruiting
N/A
100
 
neoadjuvant Docetaxel/Oxaliplatin/Xelode (DOX) ;Neoadjuvant Docetaxel/Oxaliplatin/Xelode (DOX) three weeks and eight weeks courses
the First Affiliated Hospital of Nanjing Medical University; the First Affiliated Hospital of Nanjing Medical University, research fund from department of gastric surgery
gastric cancer
 
 
ChiCTR-OPC-15006819: S-1 and raltitrexed for patients with metastatic colorectal cancer after failure to fluoropyrimidine, irinotecan and oxaliplatin.

Completed
N/A
30
 
S-1 and raltitrexed
Department of Medical Oncology, Cancer Center, The State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University.; Department of Medical Oncology, Cancer Center, The State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University., Research Fund of West China Hospital
colorectal cancer
 
 
ChiCTR-ONC-12002258: Effects of Gemcitabine, oxaliplatin and dexamethasone (GOD) as salvage treatment for elderly patients with refractory and relapsed peripheral T-cell lymphoma

Completed
N/A
30
 
Treated with Gemcitabine, oxaliplatin and dexamethasone (GOD) regimen
Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Level of the institution:, Scientific Research Program from Health Bureau of Shanghai (grant no.2010101).
relapsed or refractory peripheral T-cell lymphoma
 
 
ChiCTR-TRC-11001361: A clinical trial on efficacy and safety of intra-arterial chemotherapy and systemic venous chemotherapy for locally advanced gastric cancer

Completed
N/A
818
 
(m)Folfox6 chemo-regimen, repeated every 2 week ;(m)Folfox6 chemo-regimen, repeated every 2 week
Xijing Hospital of Digestive Diseases. The Fourth Military Medical University; Xijing Hospital of Digestive Diseases. The Fourth Military Medical University, self-financed
locally advanced gastric cancer
 
 
ChiCTR-ONC-14005147: Multicenter and prospective study of chemotherapy associated myelotoxicity among Chinese gastric cancer population receiving cytotoxic conventional regimens

Completed
N/A
1285
 
six commonly used regimens (i.e. CF/XP; EC(O)F/EC(O)X; DC(O)F/DC(O)X; PC(O)F/PC(O)X; FOLFOX4; mFOLFOX7/XELOX)
Gastrointestinal Oncology Department, Affiliated Cancer Center of Academy of Military Medical Sciences; Gastrointestinal Oncology Department, Affiliated Cancer Center of Academy of Military Medical Sciences, SHENYANG SUNSHINE PHARMACEUTICAL CO., LTD, Shenyang, China; Affiliated hospital of Academy of Military Medical Sciences
Gastric Cancer
 
 
ChiCTR-TRC-14004765: Clinical observation on the efficacy of Huangqi guizhi wuwu decoction granules for oxaliplatin-induced peripheral neuropathy

Completed
N/A
82
 
Placebo ;Huangqi guizhi wuwu decoction granules
Jiangsu Province Hospital on Integration of Chinese and Western Medicine; Level of the institution:, Supported by the Fundamental Research Funds for the Central public welfare research institutes
Tumor
 
 
RAPIDO, NCT06212128: vs LCRT vs Upfront Surgery - a Prospective Cohort Study

Active, not recruiting
N/A
57
NA
RAPIDO TNT, LCRT
Sengkang General Hospital
Rectal Cancer
05/22
06/24
NCT02836977: Maintenance Tegafur-uracil Versus Observation Following Adjuvant Oxaliplatin-based Regimen in Patients With Stage III Colon Cancer After Radical Resection

Active, not recruiting
N/A
400
RoW
tegafur-uracil, UFUR
Kaohsiung Medical University Chung-Ho Memorial Hospital
Stage III Colon Cancer
03/17
02/24
ChiCTR-TRC-14004983: Phase III Trial of neoadjuvant chemotherapy with Three drugs for advanced gastric cancer: a multicenter, open, randomized, controlled clinical study

Recruiting
N/A
300
 
Preoperative chemotherapy of DOX for 4 cycles, capecitabine 1000mg/m2, bid, p.o, 1 to 14 days; oxaliplatin 130mg/m2, ivgtt, 2h, d1, docetaxel 60mg/m2, ivgtt, d1, 21 day/cycle, operation after 2~4 weeks, and postoperative chemotherapy of XP for 4cycles after surgery ;Preoperative chemotherapy of XP for 4 cycles, capecitabine 1000mg/m2, bid, p.o, 1 to 14 days; oxaliplatin 130mg/m2, ivgtt, 2h, d1, 21 day/cycle, operation after 2~4 weeks, and postoperative chemotherapy of XP for 4cycles after surgery ;Operation after 2~4 weeks, and postoperative chemotherapy of XP for 8cycles after surgery, capecitabine 1000mg/m2, bid p.o, 1 to 14 days; oxaliplatin 130mg/m2, ivgtt, 2h, d1
Hebei Medical University affiliated Fourth Hospital; Hebei Medical University affiliated Fourth Hospital, self-raise
Advanced gastric cancer
 
 
PIPAC/PITAC, NCT02720835: Efficacy and Safety of in Gastric,Ovarian, Colorectal Cancer and Mesothelioma With Pleural Carcinomatosis.

Recruiting
N/A
200
Europe
pressurized intraperitoneal/intrathoracal aerosol chemoTx, PIPAC/PITAC
Othmar Schoeb
Colorectal Cancer, Ovarian Cancer, Gastric Cancer, Mesothelioma
02/18
02/18
PROOF, ChiCTR-OPC-15005865: Prospective, Multicenter, Registry study of Oxaliplatin (Eloxatin)/Fluorouracil based regimen for Chinese Local Advanced or Metastatic Hepatocellular Carcinoma patients ineligible for curative resection and local treatment

Recruiting
N/A
500
 
NA
81 Hospital of Chinese PLA; Level of the institution:, Sanofi (Hangzhou) Pharmaceuticals Co., Ltd
Hepatocellular Carcinoma
 
 
ChiCTR-OOC-16009575: Molecular characteristics of refractory gastric adenocarcinoma highly sensitive to trastuzumab: A study based on phosphorylated proteomics

Recruiting
N/A
76
 
Trastuzumab plus XELOX protocol
Shanghai General Hospital; Shanghai General Hospital, Clinical Research Plan of SHDC
Gastric adenocarcinoma
 
 
ChiCTR1800014296: Neoadjuvant Therapy of Locally Advanced Gastric Carcinoma by Green Tea Extract and XELOX: a prospective randomized controlled trial

Recruiting
N/A
80
 
EGCG(epigallocatechin gallate) + chemotherapy ;chemotherapy
Cancer Hospital of Shantou University Medical College; Cancer Hospital of Shantou University Medical College, Scientific research project of traditional Chinese Medicine Bureau of Guangdong Provincial
Gastric Cancer
 
 
NCT06235164: The Safety and Efficacy of Neoadjuvant Immunochemotherapy Followed by Laparoscopic Gastrectomy for Gastric Cancer

Active, not recruiting
N/A
585
RoW
immune checkpoint inhibitors: sintilimab, nivolumab, and camrelizumab
Fujian Medical University
Locally Advanced Gastric Cancer
12/22
12/25
RECOMMEND, NCT03413514: Real World Evidence for the Cycle of Neoadjuvant Chemotherapy in Gastric Cancer With Shared Decision Making

Recruiting
N/A
100
RoW
NACT, SDM, Surgery, ACT, Questionnaire
Peking University
Gastric Cancer
01/19
01/23
RSR-HCC-2019-001, NCT06261138: Survival Analysis: TACE vs. Combination Therapy in HCC

Completed
N/A
279
RoW
Transarterial chemoembolization, TACE, Systemic treatment
Zhejiang University
Hepatocellular Carcinoma
03/23
10/23
NCT03122886: Fat Emulsion in Preventing Hypersensitivity Reactions in Patients With Cancer Receiving Carboplatin or Oxaliplatin

Active, not recruiting
N/A
19
US
Fat Emulsion, FAT EMULSION, INTRAVENOUS, Intralipid, Intravenous Fat Emulsion, Placebo, placebo therapy, PLCB, sham therapy
Mayo Clinic, National Cancer Institute (NCI)
Advanced Malignant Neoplasm
07/19
12/24
ChiCTR-INR-17010977: A multicenter prospective randomized controlled trial of Folfox6 regimen in the treatment of intrahepatic cholangiocarcinoma at different stages of hepatic arterial infusion chemotherapy

Recruiting
N/A
480
 
The hepatic artery catheter Folfox6 chemotherapy ;Transcatheter arterial infusion chemotherapy after radical resection of ICC (Folfox 6 regimen) ;Whole-body (gemcitabine-based regimen) in the treatment of patients with unresectable middle and late ICC
The First Affiliated Hospital of Xi'an Jiaotong University,; The First Affiliated Hospital of Xi'an Jiaotong University, , National Scientific Foundation Grand
intrahepatic cholangiocarcinomas, ICC
 
 
CLASS-03a, NCT03468712: Laparoscopic D2 Distal Gastrectomy Following Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancers

Recruiting
N/A
166
RoW
Laparoscopic D2 distal gastrectomy
West China Hospital, Peking University Cancer Hospital & Institute, Southern Medical University, China, Shanghai Zhongshan Hospital, Chinese PLA General Hospital, Fujian Medical University Union Hospital, Ruijin Hospital, Southwest Hospital, China, RenJi Hospital, The First Affiliated Hospital with Nanjing Medical University, Fudan University, Tang-Du Hospital, Harbin Medical University, The First Hospital of Jilin University, Guangdong Provincial People's Hospital, Sir Run Run Shaw Hospital
Complications, Postoperative, Surgery--Complications, Cancer of Stomach, Chemotherapy Effect
04/20
04/23
TransValid-A, NCT03034473: Translational Validation Study to Examine KFO179-1 Biomarker Scores for the Prediction and Prognosis of Advanced Primary Resectable Rectal Cancer Stages UICC-II-IV, With a 5-Fluorouracil-based Standard Radiochemotherapy Followed by Total Mesorectal Excision.

Active, not recruiting
N/A
200
Europe
Translational Research and multimodal treatment
University Medical Center Goettingen, German Research Foundation
Locally Advanced Rectal Cancer
08/24
08/24
ChiCTR1800014815: Concurrent Neoadjuvant Chemoradiotherapy Plus Trastuzumab in the Treatment of Siewert II, III of HER-2 Positive Gastroesophageal Junction Adenocarcinoma: A Randomized, Controlled trial

Recruiting
N/A
48
 
Trastuzumab XELOX and radiotherapy ;XELOX and radiotherapy
Fourth Hospital of Hebei Medical University; Fourth Hospital of Hebei Medical University, self-raised
adenocarcinoma at gastroesophageal junction
 
 
NCT06205173: Explored About Temperature Packing Care to Improve the Quality of Life for Chemotherapy Induced Peripheral Neuropathy (CIPN) in Colorectal Cancer and Gastric Cancer Patient

Completed
N/A
18
RoW
Hot compressing, Cold compressing
National Taiwan University Hospital
Colorectal Cancer, Gastric Cancer, Chemotherapy-induced Peripheral Neuropathy
08/21
08/21
IMMUNOPAC, NCT04122885: Study of Plasma Tumor-promoting Factors and Immune Function After Laparotomy, Cytoreductive Surgery and HIPEC vs. PIPAC in Patients With Peritoneal Metastasis

Recruiting
N/A
60
Europe
PIPAC with oxaliplatin, Cytoreductive surgery and Hyperthermic IntraPeritoneal Chemotherapy, CRS and HIPEC
University Hospital Tuebingen, Icahn School of Medicine at Mount Sinai
Peritoneal Cancer, Chemotherapy-Induced Change
09/20
09/22
ChiCTR1800019445: Efficacy of Adjuvant Chemotherapy in Patients with Clinical T3b/T4, N+ Rectal Cancer Undergoing Neoadjuvant Chemoradiotherapy: A Pathology-oriented, Prospective, Multicenter, Randomized, Open-label, Parallel Group Clinical Trial

Recruiting
N/A
764
 
5-fluorouracil ;oxaliplatin combined with 5-fluorouracil ;Observation ;5-fluorouracil alone
Fudan University Shanghai Cancer Center; Fudan University Shanghai Cancer Center, Shanghai Anticancer Association
Rectal cancer
 
 
NCT04305288: Chemotherapy mFOLFIRINOX in Locally Advanced or Metastatic Cholangiocarcinoma

Recruiting
N/A
100
RoW
Shanghai Jiao Tong University School of Medicine
Cholangiocarcinoma of the Bile Duct
12/20
12/21
CELAEC, NCT02972372: Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer

Recruiting
N/A
196
RoW
CRT, concurrent chemoradiotherapy, surgery, esophagectomy
The First Affiliated Hospital of Henan University of Science and Technology, Jiangsu HengRui Medicine Co., Ltd., Anyang Tumor Hospital, 150th Hospital of PLA
Esophagus Cancer
12/20
06/21
ChiCTR-OOC-17014182: Prospective study of oxaliplatin combined with retitrexed continuous hepatic artery infusion in the treatment of advanced primary liver cancer

Recruiting
N/A
50
 
continuous hepatic artery infusion of oxaliplatin combined with retitrexide
Fujian Cancer Hospital; Fujian Cancer Hospital, institution funding
Hepatocellular Carcinoma
 
 
ChiCTR-IOR-16008729: A multicentre, open-label, randomised, controlled study of molecularly precision target therapy based on tumor molecular profiling with gemcitabine and oxaliplatin in advanced or recurrent extrahepatic cholangiocarcinoma and gallbladder carcinoma

Recruiting
N/A
152
 
GEMOX ;molecularly precision target therapy with GEMOX
Xinhua Hospital affiliated to Shanghai Jiaotong University, School of Medicine; Xinhua Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Xinhua Hospital affiliated to Shanghai Jiaotong University, School of Medicine
extrahepatic cholangiocarcinoma and gallbladder carcinoma
 
 
ChiCTR1800016946: Efficacy and safety of combination chemotherapy with LBP or oxaliplatin plus capecitabine in locally advanced or metastatic gastric cancer: a randomized, controlled, multicenter clinical trial

Recruiting
N/A
348
 
LBP combined with capecitabine ;Oxaliplatin combined with capecitabine
The first hospital of China medical university; Anhui provincial hospital, Hainan Changan International Pharmaceutical Co., Ltd.
Stomach cancer
 
 
NCT06323382: Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma

Recruiting
N/A
240
RoW
Locoregional therapy, TACE/HAIC, Bevacizumab, Atezolizumab, Tislelizumab, Toripalimab, Sintilimab, Camrelizumab
Sun Yat-sen University
Advanced Hepatocellular Carcinoma, Anti-PD1/PDL1 Antibody, Bevacizumab
12/24
12/24
NCT06333561: HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma

Recruiting
N/A
300
RoW
Hepatic arterial infusion chemotherapy, Lenvatinib, Tislelizumab, Toripalimab, Sintilimab, Camrelizumab
Sun Yat-sen University
Hepatocellular Carcinoma, Lenvatinib, PD-1 Inhibitor, Hepatic Arterial Infusion Chemotherapy
12/24
12/24
ChiCTR2000029201: A medical records based study for selection of medicine depends on clinical characteristics between fluorouracil combined with oxaliplatin and irinotecan regimens and their effects on patients' life quality

Recruiting
N/A
1400
 
mFOLFOX6 ;FOLFIRI
The First Affiliated Hospital of College of Medicine, Zhejiang University; The First Affiliated Hospital of College of Medicine, Zhejiang University, Raise Independently
Tumour
 
 
NCT06199297: Atezolizumab Plus Bevacizumab Versus Sintilimab Plus Bevacizumab With TACE and HAIC in Unresectable Hepatocellular Carcinoma

Completed
N/A
188
RoW
Atezolizumab combined with Bevacizumab, Sintilimab combined with Bevacizumab, Transcatheter arterial chemoembolization and hepatic arterial infusion chemotherapy
Sun Yat-sen University
Hepatocellular Carcinoma
07/23
07/23
ChiCTR-OOC-16008241: The predictive value of XRCC1, ERCC1, GSTP1, XPD and TS detection in the efficacy and toxicty of XELOX chemotherapy for colorectal cancer

Recruiting
N/A
854
 
XELOX protocol
Shanghai ChangZheng Hospital; Shanghai ChangZheng Hospital, self-collected funds
Colorectal cancer
 
 
NCT03777475: the Effect of Different Oxaliplatin Dose in Transarterial Infusion (TAI) in Unresectable Hepatocellular Carcinoma

Recruiting
N/A
350
RoW
transarterial infusion
Sun Yat-sen University
Hepatocellular Carcinoma
06/21
12/22
NCT04751513: Auricular Acupressure : Improves Oxaliplatin-induced Peripheral Neuropathy

Recruiting
N/A
76
RoW
auricular acupressure
Chang Gung Memorial Hospital
Oxaliplatin-induced Peripheral Neuropathy, Chemotherapy
08/21
08/21
GASPACCO, NCT04595929: Oncological Benefits of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients With T3-4 Gastric Cancer Cyt-

Recruiting
N/A
304
RoW
Staging laparoscopy, 5-Fluorouracil, 5-FU, Leucovorin, Calciumfolinat, Oxaliplatin, Docetaxel, Radical surgery, PIPAC, Adjuvant chemotherapy
St. Petersburg State Pavlov Medical University
Peritoneal Carcinomatosis, Gastric Cancer
10/21
01/29
PLAEGV, NCT04524676: Oxaliplatin-induced Portal Hypertension

Not yet recruiting
N/A
25
RoW
Individualized Treatment
Shanghai Zhongshan Hospital
Gastroesophageal Varices Hemorrhage, Colorectal Cancer, Received Oxaliplatin-based Chemotherapy
10/21
09/22
PLAEGV-DIA, NCT04524650: Early Diagnosis of Oxaliplatin-induced Portal Hypertension

Not yet recruiting
N/A
370
RoW
the level of vWF
Shanghai Zhongshan Hospital
Gastroesophageal Varices, Colorectal Cancer, Received Oxaliplatin-based Chemotherapy
10/21
09/22
A prospective clinical study of the efficacy and safety of treprilumab in combination with SOX regime for the treatment of gastric cancer, ChiCTR1900027236: A single-arm prospective clinical study for the efficacy and safety of treprilumab in combination with oxaliplatin and tegafur (SOX) for the treatment of unresectable locally advanced, recurrent or metastatic gastric and gastroesophageal junction adenocarcinoma

Recruiting
N/A
20
 
treprilumab and sox regime
Renji Hospital, School of Medicine, Shanghai Jiaotong University; Renji Hospital, School of Medicine, Shanghai Jiaotong University, self-raised
gastric cancer
 
 
ChiCTR1900024867: Efficacy observation for sequential first-line treatment of advanced metastatic pancreatic cancer with albumin combined with paclitaxel + teggio/gemcitabine + oxaliplatin: a single-arm prospective study

Recruiting
N/A
30
 
The albumin binding paclitaxel + teggio/gemcitabine + oxaliplatin regimen was sequential and alternating
Affiliated Cancer Hospital of Harbin Medical University; Affiliated Cancer Hospital of Harbin Medical University, By oneself
Locally advanced and metastatic pancreatic cancer
 
 
NCT04669977: Effects of a Glucoside- and Rutinoside-rich Material in Chemotherapy-induced Peripheral Neuropathy and Related Symptoms

Recruiting
N/A
246
RoW
Mulberry juice
Taipei Medical University
Chemotherapy-induced Peripheral Neuropathy
12/21
12/23
NCT04618367: HAIC Combined With Lenvatinib and Sintilimab for Hepatocellular Carcinoma With PVTT

Completed
N/A
30
RoW
Hepatic arterial infusion chemotherapy, Lenvatinib, TKI inhibits, Sintilimab, programmed cell death protein-1 (PD-1) antibody
Sun Yat-sen University, Second Affiliated Hospital of Guangzhou Medical University
Carcinoma, Hepatocellular, Liver Neoplasms, Sintilimab, Portal Vein Tumor Thrombus
12/21
12/22
ChiCTR1900023191: A clinical study for TAE in combination with anlotinib, oxaliplatin and raltitrexed in the sequential treatment of middle or advanced primary liver cancer (PLC)

Recruiting
N/A
80
 
TAE in combination with anlotinib, oxaliplatin and raltitrexed ;Symptomatic treatment
Center Hospital of Liutie; Center Hospital of Liutie, CHIA TAI TIANQING (CTTQ) Pharmaceutical Co., Ltd.
Heaptocellular Carcinoma,HCC
 
 
HILO-OXALI, NCT04913376: Hilotherapy-study on Prevention of Oxaliplatin-induced Peripheral Neuropathy

Recruiting
N/A
66
Europe
Hilotherapy
Universitaire Ziekenhuizen Leuven
Quality of Life, Chemotherapy-induced Peripheral Neuropathy
12/21
05/22
NCT02135887: A Trial of MB-6 for Reduction of Neutropenia Induced by Chemotherapy in Patients With Stage III Colorectal Cancer.

Recruiting
N/A
184
RoW
MB-6, Folinic acid; Fluorouracil ; Oxaliplatin, Placebo
Microbio Co Ltd
Stage III Colorectal Cancer, Neutropenia
03/22
12/22
NCT04886193: FLOT Combined With PD-1 in the First-line Treatment of Patients With Advanced Gastric Cancer and Peritoneal Metastasis

Recruiting
N/A
20
RoW
FLOT(Docetaxel+oxaliplatin+leucovorin+5-FU), Treprizumab, Tiggio capsule (S-1)
Guangdong Provincial Hospital of Traditional Chinese Medicine, Shanghai Junshi Bioscience Co., Ltd.
Chemotherapy, Gastric Cancer
05/22
05/23
NCT04996355: Organoids-on-a-chip for Colorectal Cancer and in Vitro Screening of Chemotherapeutic Drugs

Recruiting
N/A
52
RoW
comprehensive treatment after MDT discussion
Peking University People's Hospital, Peking University
Colorectal Neoplasms, Organoids
05/22
05/24
ChiCTR2000032996: Effects of External Application of Traditional Chinese Medicine Hexue Tongbi Powder on Oxaliplatin-Induced Peripheral Neuropathy Among Patients With Colorectal Cancer: an Open-Label, Randomized Controlled Trial

Not yet recruiting
N/A
100
 
Oxaliplatin-based chemotherapy, education disease related knowledge and He-Xue Tong-Bi Powder will be used ;Oxaliplatin-based chemotherapy and education disease related knowledge will be used
The First Affiliated Hospital of Guangzhou University of Chinese Medicine; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 'Dengfeng hospital' plan of the First Affiliated Hospital of Guangzhou University of traditional Chinese Medicine
Colorectal cancer
 
 
NCT03001726: To Observe the Efficacy and Safety by Comparing Chemotherapy(Docetaxel, Oxaliplatin Plus S1 ) Followed With Radical Resection Versus Chemotherapy Alone in Advanced Gastric Cancer With Single Non-curable Factor.

Enrolling by invitation
N/A
228
RoW
Gastrectomy, oxaliplatin, Eloxatin, S1, tegafur, Docetaxel, Taxotere
Shanghai Zhongshan Hospital
Gastric Cancer
06/22
12/23
ChiCTR1900021862: A randomized controlled trial for irinotecan-eluting beads transarterial chemoembolization with systemic GEMOX (gemcitabine plus oxaliplatin) versus GEMOX in patients with unresectable, local advanced or metastatic intrahepatic cholangiocarcinoma

Not yet recruiting
N/A
150
 
irinotecan DEB-TACE with GEMOX ;GEMOX treatment
Zhongshan Hospital of Fudan University; Zhongshan Hospital of Fudan University, Fund for Clinical Research, Zhongshan Hospital of Fudan University
intrahepatic cholangiocarcinoma
 
 
NCT06202781: Tumor Microenvironment in Gastric Cancer Patients Treated With Combined Immunotherapy and Chemotherapy

Recruiting
N/A
28
RoW
SOX plus PD-1 inhibitor, Gastroscopic biopsy
Chinese PLA General Hospital
Gastric Cancer, Tumor Microenvironment, Immunotherapy, Chemotherapy
06/24
07/24
NCT06378580: The Prognostic Impact of Surufatinib for the Treatment of Advanced Pancreatic Ductal Adenocarcinoma

Completed
N/A
72
RoW
Surufatinib combine immune checkpoint inhibitor, AG/FOLFIRINOX
Luo Cong
Pancreatic Cancer
07/23
04/24
NCT00430313: Effects of Acupoint Electro-stimulation on Preventing Nausea and Vomiting Induced by Cisplatin or Oxaliplatin

Withdrawn
N/A
100
NA
Electro-Stimulation of Yongquan (K1) Acupoint, ES
M.D. Anderson Cancer Center, National Cancer Institute (NCI)
Liver Cancer, Liver Metastasis
08/22
08/22
COBRA, NCT03451370: First-line Combination of Capecitabine and Oxaliplatin Plus Bevacizumab in Elderly Patients With Metastatic Colorectal Cancer

Active, not recruiting
N/A
121
Europe
Capecitabine, Oxaliplatin, Bevacizumab
Istituto Oncologico Veneto IRCCS
Elderly Metastatic Colorectal Cancer Patients
07/24
12/24
NCT05544812: A Small-sample, Real-world Study of Sintilimab Plus Bevacizumab/Cetuximab Plus XELOX Regimen for Conversion Therapy in Patients With Advanced Colorectal Cancer

Recruiting
N/A
10
RoW
Sintilimab ,bevcizumab/cetuximab,XELOX
Xijing Hospital
Colorectal Cancer
09/22
06/23
ChiCTR2000037568: A multicenter study on the efficacy and influencing factors of Insect Compound Particle in the treatment of MMR related stage III colorectal cancer

Not yet recruiting
N/A
262
 
Insect compound Particels combined with mfolfox6 ;Placebo of Insect compound Particles combined with mfolfox6
Shanghai Municipal Hospital of Traditional Chinese Medicine; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai Shenkang Hospital Development Center
colorectal cancer
 
 
ChiCTR2000036864: A multicenter study on the efficacy and influencing factors of Insect Compound Particle in the treatment of MMR related stage III colorectal cancer

Not yet recruiting
N/A
490
 
Insect Compound Particle combine with mFOLFOX6 ;placebo of Insect Compound Particle combine with mFOLFOX6
Shanghai Municipal Hospital of Traditional Chinese Medicine; Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai Shenkang Hospital Development Center
colorectal cancer
 
 
ChiCTR2000036228: Clinical study of Hongai Tongluo decoction combined with Du moxibustion in the treatment of Oxaliplatin Neurotoxicity

Not yet recruiting
N/A
300
 
Hongai Tongluo decoction combined with Du moxibustion and chemotherapy ;Chemotherapy
Shanghai Longhua University Hospital of traditional Chinese Medicine; Shanghai Longhua University Hospital of traditional Chinese Medicine, Special funds
Digestive tract tumor
 
 
ChiCTR-ONC-17010430: A single-arm exploratory clinical research of S1/ oxaliplatin chemotherapy plus Apatinib in the conversion therapy of metastatic gastric cancer.

Recruiting
N/A
30
 
S1/ oxaliplatin chemotherapy plus Apatinib
Fujian Cancer Hospital; Fujian Cancer Hospital, Hengrui Company, Jiangsu, China
Gastric cancer
 
 
ChiCTR2000038884: Clinical study on acupuncture in the treatment of oxaliplatin-induced peripheral neurotoxicity

Recruiting
N/A
84
 
acupuncture ;sham acupuncture
Hospital of Chengdu University of Traditional Chinese Medicine; Hospital of Chengdu University of Traditional Chinese Medicine, Special funds
Oxaliplatin-induced peripheral neurotoxicity
 
 
ChiCTR2100046237: Effect of prebiotics in regulating gut microbiota of patients with colorectal cancer on the prognosis of fluorouracil treatment

Recruiting
N/A
60
 
Volunteers in Xylooligosaccharide group received Xylooligosaccharide 3 g/d in addition to standard capecitabine combined with oxaliplatin adjuvant chemotherapy. ;The blank control group received no additional nutritional intervention on the basis of standard capecitabine combined with oxaliplatin adjuvant chemotherapy.
The Affiliated Hospital of Jiangnan University; The Affiliated Hospital, Jiangnan University, Self-raised
Colorectal cancer
 
 
ChiCTR1900027023: A non-inferiority study of apatinib versus bevacizumab combined with XELOX regimen in the treatment of metastatic colorectal cancer

Recruiting
N/A
120
 
Apatinib 250mg po, qd, continuous taken; XELOX: Oxaliplatin 135 mg/m2 Ivgtt d1, Capecitabine 1000mg/m2 d1-14, q3w ;Bevacizumab 7.5mg/kg, q3w; XELOX: Oxaliplatin 135 mg/m2 Ivgtt d1, Capecitabine 1000mg/m2 d1-14, q3w
Tangshan People's Hospital; Tangshan people's Hospital, self-raise
colorectal cancer
 
 
ChiCTR1900028417: First-Line XELOX Plus Anlotinib Followed by Single-Agent Anlotinib as Maintenance Therapy in mCRC Patients

Recruiting
N/A
29
 
Anlotinib+XELOX
Sichuan Cancer Hospital and Research Institute; Sichuan Cancer Hospital and Research Institute, Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Colorectal Carcinoma
 
 
NCT04432402: Lenalidomide in Combination With R-GemOx in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma

Recruiting
N/A
124
RoW
Lenalidomide, Rituximab, Gemcitabine, oxaliplatin
The First Affiliated Hospital with Nanjing Medical University
Diffuse Large B Cell Lymphoma
12/22
12/24
ChiCTR2000036551: Establishment and validation of therapeutic effect prediction model of first line treatment of bevacizumab combined with mFOLFOX6 in Ras mutant colorectal cancer patients with liver metastasis

Not yet recruiting
N/A
 
Zhongshan Hospital, Fudan University; Zhongshan Hospital, Fudan University, Shanghai Shenkang Hospital Development Center
colorectal cancer
 
 
NCT04521491: A Trial of Adjuvant Therapy After Hepatocarcinoma Resection Based on Folate Receptor-positive Circulating Tumor Cells

Not yet recruiting
N/A
184
RoW
FOLFOX4(infusional fluorouracil [FU], leucovorin [LV], and oxaliplatin [OXA]).
Eastern Hepatobiliary Surgery Hospital
Hepatocellular Carcinoma
12/22
12/23
ChiCTR2200055659: A prospective clinical study of PD-1 inhibitor combined with albumin-paclitaxel + oxaliplatin + S-1 chemotherapy for perioperative treatment of locally advanced gastric cancer

Recruiting
N/A
30
 
Cangzhou Central Hospital; Cangzhou Central Hospital, Wu Jieping Medical Foundation
Gastric Cancer
 
 
NCT05247996: TACE Combined With "Target Immune" Therapy for First-line Treatment in the Treatment of Intrahepatic Cholangiocarcinoma

Not yet recruiting
N/A
98
NA
Transcatheter arterial chemoembolization, TACE Thrapy, Multi-target Drug Therapy, Target Therapy, Immunocheckpoint Inhibitor Therapy, Immune Therapy, Systemic Intravenous Chemotherapy, Traditional Chemotherapy
The Central Hospital of Lishui City
Intrahepatic Cholangiocarcinoma
12/22
12/23
ChiCTR2000029082: Apatinib combined with continuous hepatic arterial infusion of oxaliplatin and raltitrexed in hepatocellular carcinoma with extrahepatic spread: a prospective study

Recruiting
N/A
30
 
Oral apatinib combined with continuous hepatic arterial infusion of oxaliplatin and raltitrexed
Fujian Cancer Hospital; Fujian Cancer Hospital, Hospital funding
Hepatocellular Carcinoma
 
 
NCT05233358: HAIC Combined With Second-line "Target Immunity" for HCC With TACE Standard Treatment Low Response or Failure

Not yet recruiting
N/A
176
NA
Hepatic Artery Infusion Chemotherapy, HAIC, Transarterial Chemoembolization, TACE, Regorafenib, second-line target drug, Immune Checkpoint Inhibitors, Camrelizumab, Sintilimab, Nivolumab, Pembrolizumab, Toripalimab
The Central Hospital of Lishui City
Hepatocellular Carcinoma
02/23
02/25
NCT05262452: Concurrent FOLFIRINOX Plus High Intensity Focused Ultrasound for Pancreatic Cancer

Recruiting
N/A
60
RoW
ALPIUS 900, an ultrasound-guided high intensity focused ultrasound system, FOLFIRINOX regimen
Seoul National University Hospital, Focused Ultrasound Foundation, Synex Consulting Ltd
Pancreatic Cancer Non-resectable, Chemotherapy Effect, Ultrasound Therapy
03/23
12/24
NCT05178745: A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection

Completed
N/A
140
NA
Fluorouracil, Aflibercept, ZALTRAP®, Irinotecan, CAMPTOSAR®
Sanofi
Metastatic Colorectal Cancer, Colorectal Neoplasms
05/22
05/22
ChiCTR2100045907: Prevention effects of Methylcobalamin on peripheral neuropathy induced by XELOX regimen: a single-center, double-blind, placebo-controlled randomized study

Recruiting
N/A
70
 
All patients should not use drugs that may affect neurological symptoms during chemotherapy and ask for strict cold avoidance. ;From the first cycle of chemotherapy, oral methylcobalamin tablets (Mikobao)500 ug , orally, tid, 1 to 14 days and 21 days for 1 cycle.
Guangzhou Zengcheng District People's Hospital; Guangzhou Zengcheng District People's Hospital, Guangzhou Science and Technology Bureau
Oncology
 
 
ChiCTR2100046429: Clinical study of camrelizumab combined with apatinib and SOX regimen in first-line treatment of advanced gastric cancer

Recruiting
N/A
30
 
Camrelizumab + apatinib + ticgio + oxaliplatin
The Second Affiliated Hospital of Anhui Medical University; The Second Affiliated Hospital of Anhui Medical University, Jiangsu Hengrui Pharmaceutical Co., Ltd
gastric cancer
 
 
NCT06196554: Gastric Cancer Organoids in the Screening of Neoadjuvant Drugs

Recruiting
N/A
40
RoW
Oxaliplatin, Irinotecan (SN-38), 5-Fluorouracil, Paclitaxel, Pembrolizumab, Nivolumab
Dong Bing Zhao
Gastric Cancer, Organoid, Neoadjuvant Therapy
06/24
06/24
FIRENOX, NCT06251297: Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer

Active, not recruiting
N/A
40
Europe
Foot reflexology
University Hospital, Toulouse
Colorectal Cancer
12/24
12/25
ChiCTR2000035682: Effectiveness and safety of Fruquintinib combined SOX for conversion therapy of unresectable advanced gastric cancer (stage IV A): a single-arm, single-center, prospective clinical trial

Not yet recruiting
N/A
35
 
Fruquintinib combined with S-1 and oxaliplatin
Shanghai Tenth People's Hospital; Shanghai Tenth People's Hospital, self-finacing
Gastric Cancer
 
 
NCT06199115: Prevention of Neuropathic Pain From Oxaliplatin by Photobiomodulation

Recruiting
N/A
70
Europe
Photobiomodulation
Saint-Gregoire Private Hospital Center
Cancer of the Gastrointestinal Tract
03/25
04/25
NCT04923620: Neoadjuvant Cetuximab + Chemotherapy Combined With Short-course Radiotherapy

Recruiting
N/A
51
RoW
cetuximab+mFOLFOX6, short-course radiotherapy
Shanghai Minimally Invasive Surgery Center
Neoadjuvant Treatment, Rectal Cancer, Cetuximab, Radiotherapy
08/24
06/25
NCT06322147: Chemotherapy With Cetuximab as Conversion Therapy in RAS/BRAF WT Unresectable Liver Metastasis Right-sided Colon Cancer

Recruiting
N/A
50
RoW
Doublet or triplet chemotherapy combined with cetuximab
Qilu Hospital of Shandong University
Colon Cancer
12/24
12/25
ChiCTR2200055514: Effect of half-dose BYVASDA versus standard dose Avastin combined with mFOLFOX6 chemotherapy on metastatic colorectal cancer : A multicenter, open-label, parallel, randomized controlled clinical study

Recruiting
N/A
571
 
mFOLFOX6 +half-dose Bevacizumab (BYVASDA) ;mFOLFOX6 + half-dose Bevacizumab (Avastin)
Sichuan Cancer Hospital; Sichuan Cancer Hospital, self-financing and corporate sponsorship
metastatic colorectal cancer
 
 
ICTCPTLAGC, NCT05385900: Immune Combined Targeted and Chemotherapy in Perioperative Treatment of Locally Advanced Gastric Cancer

Not yet recruiting
N/A
57
NA
Penpulimab combination with anlotinib and chemotherapy, Teggio, Oxaliplatin
Xijing Hospital
Gastric Cancer
06/23
06/24
ORCHESTRA, NCT01792934: Chemotherapy and Maximal Tumor Debulking of Multi-organ Colorectal Cancer Metastases

Recruiting
N/A
478
Europe
XELOX regimen according to standard procedures, FOLFOX regimen according to standard procedures, Surgery, radiofrequency ablation (RFA), transarterial chemo-embolization using irinotecan drug-eluted beads ((DEBIRI-)TACE), stereotactic body radiation therapy (SBRT), Bevacizumab, tumor biopsy
Radboud University Medical Center, Erasmus Medical Center
Multi-organ Metastatic Colorectal Cancer
07/23
07/25
MIRROR, NCT06204484: MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer

Recruiting
N/A
349
RoW
CAPEOX adjuvant therapy, deferred CAPEOX adjuvant therapy, mFOLFOXIRI intensive adjuvant therapy
Sun Yat-sen University, Guangzhou Burning Rock Dx Co., Ltd.
Colorectal Cancer
07/28
07/28
ESCORT, NCT03676517: Evaluation of Efficacy, Quality of Life and Cost Effectiveness of Short-course Radiotherapy Followed by Capecitabine Plus Oxaliplatin chemotheRapy and TME for High-risk Rectal Cancer ( Trial)

Not yet recruiting
N/A
31
RoW
preoperative short-course radiotherapy
Yonsei University
Locally Advanced Rectal Cancer
08/23
08/23
ChiCTR2000034829: Camrelizumab Plus Apatinib Versus Chemotherapy for Initial Primary Unresectable Hepatic Carcinoma: a Randomized, Controlled, Single-Center, Phase II Study

Not yet recruiting
N/A
60
 
Camrelizumab Plus Apatinib ;Fluorouracil combined with oxaliplatin chemotherapy
Shengjing Hospital Affiliated to China Medical University; Shengjing Hospital Affiliated to China Medical University, Independent project
Hepatic Carcinoma
 
 
ChiCTR2000035210: Clinical study on the adjuvant treatment of postoperative cholangjocinoma with duvalizumab combined with GEMOX (gemcitabine+oxaliplatin)

Recruiting
N/A
40
 
duvalizumab combined with GEMOX (gemcitabine+oxaliplatin)
Chinese PLA General Hospital (the 301st Hospital); Chinese PLA General Hospital (the 301st Hospital), self-funding
cholangiocarcinoma
 
 
ChiCTR2200062090: Safety and efficacy analysis of apatinib combined with oxaliplatin and capecitabine in neoadjuvant chemotherapy for locally advanced gastric cancer

Recruiting
N/A
30
 
neoadjuvant chemotherapy
The First Affiliated Hospital of USTC WEST district; The First Affiliated Hospital of USTC WEST district, self-raised
gastric
 
 
NCT04415892: The Role of TRP Channels in CIPN

Recruiting
N/A
240
Europe
Cinnamaldehyde and capsaicin
Universitaire Ziekenhuizen Leuven
Chemotherapy-induced Peripheral Neuropathy
09/23
09/23
NCT06430515: The Clinical Efficacy and Safety of Intratumoral Injection of Chemotherapy for Advanced Solid Tumors

Recruiting
N/A
200
RoW
Intratumoral Injection of Chemotherapy
Wuxi People's Hospital
Intratumoral Injection, Cancer
12/27
12/28
NCT06048081: Early Access Program for Zolbetuximab

Available
N/A
Europe, US
zolbetuximab, IMAB362
Astellas Pharma Global Development, Inc.
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma Cancer, Metastatic Gastric Adenocarcinoma Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
 
 
ChiCTR2200063922: Capecitabine enhances sensitivity to oxaliplatin in advanced gastric cancer and the effects on patients' FOXP1 and GGT levels

Not yet recruiting
N/A
152
 
Capecitabine + oxaliplatin ;Oxaliplatin
Fuwai Central China Cardiovascular Hospital; Fuwai Central China Cardiovascular Hospital, Fuwai Central China Cardiovascular Hospital
gastric cancer
 
 
NCT06389552: Long-term Observational Study to Evaluate the DFS and OS of Adjuvant FOLFIRINOX Regimen in Pancreatic Cancer Patients

Recruiting
N/A
36
RoW
HK inno.N Corporation
Adjuvant Chemotherapy
12/26
12/27
ChiCTR2200064999: A single-arm, single-center clinical study on the safety, tolerability and anti-tumor effect of BM601 for TACE in the treatment of hepatocellular carcinoma

Recruiting
N/A
8
 
Oxaliplatin + adriamycin (at least 2 mL) + BM601 lipiodol suspension (3 ml) hepatic artery embolization
Lishui Central Hospital; Suzhou Baimai Biomaterials & Pharmaceutics CO., LTD, Self-raised
Tumor
 
 
ChiCTR2000038494: Hepatic arterial infusion chemotherapy (HAIC) versus transcatheter arterial chemoembolization (TACE) for unresectable hepatocellular carcinoma: a multicenter randomized controlled trial

Recruiting
N/A
380
 
high-dose chemotherapy (oxaliplatin, leucovorin, and fluorouracil) was continuously perfused through the hepatic artery ;A mixture of iodized oil and chemotherapeutic agents was injected through the hepatic artery
Sun Yat-Sen University Cancer Center; Sun Yat-Sen University Cancer Center, none
Hepatocellular Carcinoma
 
 
NCT02428101: Oxaliplatin - Induced Peripheral Neuropathy in Patients With Gastrointestinal Tract Cancer

Enrolling by invitation
N/A
80
RoW
polymorphism analysis
Ain Shams University
Gastrointestinal Tract Cancer, Peripheral Neuropathy
02/24
04/24
NCT06128252: Clinical Study of Taurine Combined With Neoadjuvant Chemo-Immunotherapy for Treatment of Locally Advanced Gastric Cancer

Recruiting
N/A
48
RoW
Taurine, Serplulimab, XELOX regimen, FLOT regimen
Tang-Du Hospital
Gastric Cancer
12/24
12/24
NCT06157216: Minimal Residual Disease-guided Adjuvant Therapy for Gastric Cancer

Recruiting
N/A
85
RoW
MRD-guided therapy
Qilu Hospital of Shandong University, Shandong Provincial Hospital, Jinan Central Hospital, Yantai Yuhuangding Hospital, The Affiliated Hospital of Qingdao University
Stage II-III Gastric Cancer
04/27
04/29
 

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