Recruiting

2/3

40

RoW

Experimental drug, Tilelizumab combined with chemotherapy

Second Affiliated Hospital, School of Medicine, Zhejiang University

Colorectal Cancer, Liver Metastases

02/24

09/24

Recruiting

2/3

375

RoW

Tislelizumab

Beijing Friendship Hospital, Beijing Chao Yang Hospital, Peking University Cancer Hospital & Institute, CHINA-JAPEN FRIENDSHIP HOSPITAL, Peking Union Medical College Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Fudan University, Changhai Hospital, RenJi Hospital, Sir Run Run Shaw Hospital, affiliated with the Zhejiang University School of Medicine, Shandong Provincial Hospital, Zhongnan Hospital of Wuhan University & Second Clinical Hospital of Wuhan University, The First Affiliated Hospital of Zhengzhou University, West China School of Medicine and West China Hospital, Sichuan University, Sichuan Academy of Medical Sciences, The Sixth Affiliated Hospital, Sun Yat-sen University, The First Hospital of Jilin University, First Hospital of China Medical University, Army Medical Center of PLA, The First Affiliated Hospital of Anhui Medical University

Locally Advanced Rectal Carcinoma

12/26

12/26

Recruiting

2/3

84

RoW

Fruquintinib, Fruzaqla, Fluorouracil, 5-FU, Oxaliplatin, L01XA03

Sun Yat-sen University

Colorectal Cancer

12/25

12/29

Recruiting

2/3

RoW

RemeGen Co., Ltd.

Gastric Cancer

07/24

07/25

Active, not recruiting

2/3

348

Europe, RoW

Nivolumab, Rituximab, Gemcitabine, Oxaliplatin

Universität des Saarlandes, Bristol-Myers Squibb, Lymphoma Study Association, University of Leipzig

Lymphoma, Non-Hodgkin

11/24

11/24

Recruiting

2/3

348

US, RoW

Oxaliplatin, Duloxetine Hydrochloride, Duloxetine, Quality-of-Life Assessment, Questionnaire Administration, Placebo

Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)

Stage II Colorectal Cancer AJCC v8, Stage III Colorectal Cancer AJCC v8

02/25

12/25

Enrolling by invitation

2/3

308

RoW

mFOLFIRINOX, mFOLFOX 6

Chungnam National University Hospital, Boryung Pharmaceutical Co., Ltd

Colon Cancer Stage III

03/25

03/28

Recruiting

2/3

40

RoW

Tislelizumab in Combination with Oxaliplatin and Tegafur

Zhejiang University

Liver Metastases

08/25

12/25

Recruiting

2/3

260

Europe, Canada, US, RoW

Zilovertamab vedotin, MK-2140, VLS-101, Rituximab, Rituxan®/mabthera, Truxima® (rituximab-abbs), RUXIENCE®), Gemcitabine, Gemzar®, Oxaliplatin, Eloxatin®, Bendamustine, Bendeka®, Treanda®, Belrapzo®

Merck Sharp & Dohme LLC, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., MERCK SHARP & DOHME LLC. UNA SUSSIDIARIA DI MERCK & CO. INC.

DLBCL, Diffuse Large B-Cell Lymphoma

06/27

06/27

Active, not recruiting

2/3

537

Canada, US, RoW

Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16, VP 16-213, VP 16213, VP-16, VP-16-213, VP16, Fluorouracil, 5 Fluorouracil, 5 Fluorouracilum, 5 FU, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-Fu, 5FU, AccuSite, Carac, Fluoro Uracil, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757, Ro-2-9757, Gemcitabine, dFdC, dFdCyd, Difluorodeoxycytidine, Irinotecan, Laboratory Biomarker Analysis, Oxaliplatin, 1-OHP, Ai Heng, Aiheng, Dacotin, Dacplat, Diaminocyclohexane Oxalatoplatinum, Eloxatin, Eloxatine, JM-83, Oxalatoplatin, Oxalatoplatinum, RP 54780, RP-54780, SR-96669, Patient Observation, Active Surveillance, deferred therapy, expectant management, Observation, Watchful Waiting, Resection, Surgical Resection, Sorafenib, BA4 43 9006, BAY 43-9006, Bay-439006, Vincristine Sulfate, Kyocristine, Leurocristine Sulfate, Leurocristine, sulfate, Oncovin, Vincasar, Vincosid, Vincrex, Vincristine, sulfate

Children's Oncology Group, National Cancer Institute (NCI)

Childhood Hepatocellular Carcinoma, Childhood Malignant Liver Neoplasm, Fibrolamellar Carcinoma, Hepatoblastoma, Hepatocellular Malignant Neoplasm, Not Otherwise Specified

06/26

06/26

Active, not recruiting

2/3

700

US

GRT-C901, GRT-R902, Atezolizumab, Tecentriq, Ipilimumab, Yervoy, Fluoropyrimidine plus leucovorin, Xeloda, Bevacizumab, Avastin

Gritstone bio, Inc.

Colorectal Neoplasms

03/27

03/27

Recruiting

2/3

1075

Europe

Induction chemotherapy - modified FOLFIRINOX regimen, Early tumor response evaluation by MRI volumetry, Radiochemotherapy Cap 50, Radical proctectomy with total mesorectal excision

Institut du Cancer de Montpellier - Val d'Aurelle

Locally Advanced Malignant Neoplasm, Rectal Carcinoma

08/27

08/27

Recruiting

2/3

758

RoW

Docetaxel, Oxaliplatin, Leucovorin, Fluorouracil

Ukrainian Society of Clinical Oncology

Gastric Cancer, Stomach Cancer, GastroEsophageal Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Advanced Gastric Adenocarcinoma, Gastric Neoplasm, Stomach Neoplasm, Gastrointestinal Cancer, Advanced Gastroesophageal Junction Adenocarcinoma, Advanced Gastric Carcinoma

12/27

12/31

Not yet recruiting

2/3

588

RoW

Sintilimab, Immune checkpoint inhibitor, Short-course radiotherapy, hypofraction, CAPOX/mFOLFOX, neoadjuvant chemotherapy

Chinese Academy of Medical Sciences

Rectal Neoplasms Malignant, Radiotherapy

07/28

07/30

Recruiting

2b

140

RoW

Tislelizumab, S-1, Oxaliplatin, Nab paclitaxel, Radiation

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Gastric Cancer, Gastroesophageal-junction Cancer

02/27

08/27

Recruiting

2a

20

US

Digoxin, Lanoxin, Digitek, Digox, 5Fluorouracil, Adrucil, 5-FU, Calcium Leucovorin, Folinic Acid, Irinotecan, Camptothecin-11, CPT-11, Camptosar, Oxaliplatin, Eloxatin

University of Nebraska, National Cancer Institute (NCI)

Pancreas Cancer, Adenocarcinoma of the Pancreas

02/25

02/25

Not yet recruiting

2

39

 

Australasian Leukaemia and Lymphoma Group (ALLG), Australasian Leukaemia and Lymphoma Group (ALLG)

Diffuse Large B-Cell Lymphoma

 

 

Recruiting

2

30

 

Princess Alexandra Hospital, Princess Alexandra Hospital,, Sanofi Synthelabo

Histologically confirmed localised squamous cell carcinoma of the oesophagus, Adenocarcinoma of the oesophagus

 

 

No longer recruiting

2

300

Japan

Avastin (bevacizumab) - Roche, irinotecan - Generic mfg., oxaliplatin - Generic mfg., 5-fluorouracil - Generic mfg., Erbitux (cetuximab) - Eli Lilly, EMD Serono

Colorectal cancer

 

 

Recruiting

2

140

 

The Walter and Eliza Hall Institute of Medical Research, Victorian Comprehensive Cancer Centre

Metastatic Colorectal Cancer

 

 

Recruiting

2

120

 

Australasian Gastro-Intestinal Trials Groups (AGITG), Australian Government Department of Health, Medical Research Future Fund (MRFF)

PANCREATIC CANCER

 

 

Active, not recruiting

2

27

Japan

capecitabine - Generic mfg., oxaliplatin - Generic mfg.

Osaka General Medical Center

Rectal cancer

 

 

Recruiting

2

90

China

Aidixi (disitamab vedotin) - Rongchang Pharma, Pfizer, Loqtorzi (toripalimab) - Shanghai Junshi Biosci, Coherus Biosci, capecitabine - Generic mfg., oxaliplatin - Generic mfg.

Remegen Biopharmaceutical (Yantai) Co., Ltd

HER2-expressing resectable locally advanced gastric/gastroesophageal junction adenocarcinoma

 

 

Recruiting

2

80

 

chemotherapy ;Chemotherapy combined with immunotherapy

Chinese Academy of Medical Sciences Tumor Hospital; Chinese Academy of Medical Sciences Tumor Hospital, self-finance

gastric cancer

 

 

Ongoing

2

110

Europe

Eloxatin, Powder for solution for infusion, Eloxatin

Erasme Hospital - Department of Gastroenterology

advanced rectal adenocarcinoma

 

 

Completed

2

200

 

TACE with gemcitabine combined oxaliplatin regimen ;TACE with gemcitabine combined oxaliplatin regimen

Fujian Provincial Tumour Hospital; Level of the institution：, Self-funded

Hepatocellular Carcinoma

 

 

Recruiting

2

140

Europe

capecitabine, docetaxel, epirubicin hydrochloride, oxaliplatin

All Ireland Cooperative Oncology Research Group

Adenocarcinoma of the Gastroesophageal Junction, Esophageal Cancer, Gastric Cancer

12/09

 

Available

2

US

docetaxel oxaliplatin

Fudan University, Chinese Anti-Cancer Association

Triple Negative Local Advanced Breast Cancer

 

 

Ongoing

2

71

Europe

Concentrate for solution for infusion, Tablet, TAXOTERE*INFUS FL 160MG/8ML, OXALIPLATINO TEVA*INF 100MG/20, XELODA*120CPR RIV 500MG

CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO, Centro di Riferimento Oncologico IRCCS CRO Aviano

patients with metastatic gastric carcinoma pazienti affetti da carcinoma gastrico metastatico, patients with metastatic gastric carcinoma pazienti affetti da carcinoma gastrico metastatico, Diseases [C] - Cancer [C04]

 

 

Recruiting

2

40

 

S1:BSA<1.25 m2, 40 mg*2/day; BSA>=1.25 m2,<1.5 m2, 50 mg*2/day; S1: BSA<1.25 m2, 40 mg*2/day; BSA >=1.25 m2,<1.5 m2, 50 mg*2/day; BSA>=1.5 m2, 60 mg*2/day)* 7days; calcium folinate: 25 mg*2/day*7days; oxaliplatin: 85 mg/m2 iv.in 3 hours * 1 day. Repeat every 2 weeks

Sun Yat-Sen University Cancer Center; Dapeng Pahrmic Information Consulting Co., Ltd, Dapeng Pahrmic Information Consulting Co., Ltd.

Advanced-stage colorectal carcinoma

 

 

Not yet recruiting

2

50

Europe

oxaliplatin, 5-fluorouracil, levofolinate, Concentrate for solution for infusion, Solution for infusion, Powder for solution for infusion

IRCCS ISTITUTO SCIENTIFICO ROMAGNOLO PER LO, IRCCS IRST

resectable rectal carcinoma, resectable rectal carcinoma, Diseases [C] - Cancer [C04]

 

 

Active, not recruiting

2

30

 

Peter MacCallum Cancer Centre, Roche Products Pty Limited

Primary rectal cancer, Metastatic rectal cancer

 

 

Ongoing

2

160

Europe

oxaliplatin, irinotecan, Avastin, S1, 23388, Concentrate and solvent for solution for injection/infusion, Concentrate and solvent for solution for infusion, Capsule, hard, Oxaliplatin, Irinotecan, Avastin, Teysuno

Odense University Hospital, Odense University Hospital

Treatment of older (≥ 70 years) patients with metastatic colorectal cancer, Colorectal cancer, Diseases [C] - Cancer [C04]

 

 

Not yet recruiting

2

276

Europe

Solution for infusion, Solution for injection/infusion, Solution for injection, Powder for concentrate for solution for infusion, Campto, Fluorouracile Ebewe, Elvorine, GEMZAR, ELOXATINE

Fédération Francophone de Cancérologie Digestive, Fédération Francophone de Cancérologie Digestive

metastatic pancreas adenocarcinoma Adénocarcinome pancréatique métastatique, advanced pancras cancer cancer avancé du pancréas, Diseases [C] - Cancer [C04]

 

 

Ongoing

2

27

Europe

Irinotecan, Cetuximab, Irinotecan, Cetuximab, Concentrate for solution for infusion, Solution for infusion, Erbitux 5mg/ml solution for infusion.

G.O.N.O. (Gruppo Oncologico Nord Ovest), Merck Serono SpA, G.O.N.O. (Gruppo Oncologico Nord Ovest)

metastatic colonrectal cancer KRAS, NRAS and BRAF wild type. carcinoma colon retto metastatico NRAS,KRAS e BRAF non mutato., metastatic tumor of colon-rectum without mutation of genes KRAS, NRAS and BRAF, Diseases [C] - Cancer [C04]

 

 

Completed

2

47

 

pre-operative radiotherapy with concurrent capecitabine and oxaliplatin

Sun Yat-sen University Cancer Center; None, None

Rectal cancer

 

 

Completed

2

257

US

Oxaliplatin, Leucovorin Calcium, Fluorouracil, Carboplatin, Paclitaxel, Positron Emission Tomography, Computed Tomography, Radiation Therapy

Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)

Adenocarcinoma of the Gastroesophageal Junction, Esophageal Cancer

11/15

04/23

Ongoing

2

46

Europe

Erbitux, Eloxatin, EMD271786, Erbitux, Eloxatin, Erbitux, Eloxatin

Technical University of Munich, Verein für Tumorforschung

advanced gastro-oesophageal adenocarcinoma

 

 

Ongoing

2

43

Europe

Gemcitabina (Gemzar®), Oxaliplatin, Gemzar, Eloxatin, Gemzar, Eloxatin

ACROSS

METASTATIC ADENOCARCINOMA OF UNKNOWN PRIMARY SITE

 

 

Ongoing

2

70

Europe

gemcitabine, oxaliplatin, LY188011, Gemzar 200 mg, Eloxatin 5 mg/ml, Gemzar 1g, Gemzar 200 mg, Eloxatin 5 mg/ml, Gemzar 1g

Eli Lilly and Company Limited

Relapsed or Refractory Neuroblastoma or Miscellaneous Solid Non-CNS Tumors

 

 

Ongoing

2

43

Europe

XELODA*120CPR RIV 500MG, ELOXATIN*IV 1FL POLV 100MG, XELODA*120CPR RIV 500MG, ELOXATIN*IV 1FL POLV 100MG

AZIENDA SANITARIA OSPEDALIERA \"S. GIOVANNI BATTISTA DI TORINO\"

rectal cancer

 

 

Ongoing

2

81

Europe

LEDERFOLIN*EV 1FL LIOF 175MG, FLUOROURACILE TEVA*IV FL 5G, ELOXATIN*IV 1FL POLV 100MG, ALOXI*1FL 250MCG 5ML, SOLDESAM*INIET 3F 1ML 4MG, LEDERFOLIN*EV 1FL LIOF 175MG, FLUOROURACILE TEVA*IV FL 5G, ELOXATIN*IV 1FL POLV 100MG, ALOXI*1FL 250MCG 5ML, SOLDESAM*INIET 3F 1ML 4MG

GOIM GRUPPO ONCOLOGICO MERIDIONALE

patientes resected for colon cancer and treated with moderate emetogenus

 

 

Ongoing

2

50

Europe

Powder for infusion*, Powder and solvent for solution for infusion

AZIENDA UNITA SANITARIA LOCALE N 12 DI VIAREGGIO

Females with metastatic breah cancer with her2 receptor overexepression and PERFORMANCE STATE-PS ECOG from 0 to 2

 

 

Ongoing

2

55

Europe

Panitumumab, ELOXATIN*IV 1FL POLV 50MG, FLUOROURACILE TEVA*IV 5FL250MG, ELOXATIN*IV 1FL POLV 50MG, FLUOROURACILE TEVA*IV 5FL250MG

AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI

rectal carcinoma

 

 

 

2

55

Europe

Erbitux, EMD271786, Erbitux, Erbitux

Merck KGaA, MERCK S.P.A.

Metastatic colon rectal carcinoma

 

09/10

Ongoing

2

34

Europe

ELOXATINE 5mg/ml, solution à diluer pour perfusion, Taxotere 80 mg solution à diluer pour perfusion, Cisplatine DAKOTA Pharm, Fluorouracile DAKOTA, ELOXATINE 5mg/ml, solution à diluer pour perfusion, Taxotere 80 mg solution à diluer pour perfusion, Cisplatine DAKOTA Pharm, Fluorouracile DAKOTA

Institut Sainte Catherine

Adénocarcinome gastrique

 

 

Ongoing

2

49

Europe

FARMORUBICINA, ELOXATIN*INFUS 1FL 20ML 5MG/ML, XELODA*60CPR RIV 150MG, XELODA*120CPR RIV 500MG, FARMORUBICINA, ELOXATIN*INFUS 1FL 20ML 5MG/ML, XELODA*60CPR RIV 150MG, XELODA*120CPR RIV 500MG

CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO

PATIENTS WITH OPERABLE GASTRIC ADENOCARCINOMA

 

 

Ongoing

2

179

Europe

Oxaliplatino, Ácido Folínico, 5-Fluorouracilo, ERBITUX 5 mg/ml solución para perfusión, ERBITUX 5 mg/ml solución para perfusión

ACROSS:Associació Catalana per a la Recerca Oncològica i les seves implicacions sanitàries i Socials

Cáncer colorectal metastásico KRAS tipo natural

 

 

Ongoing

2

100

Europe

capecitabine, oxaliplatin, xeloda, Eloxatin, xeloda, Eloxatin

Herlev Hospital

Breast cancer with liver metastases and limited extrahepatic metastases

 

 

Ongoing

2

49

Europe

not appl., not applicable, not apll., not applicable, Eloxantin (5 mg/ml), Taxotere 80mg Konzentrat und Lösungsmittel zur Herstellung einer Infusionslösung, Taxotere 20mg Konzentrat und Lösungsmittel zur Herstellung einer Infusionslösung, Eloxantin (5 mg/ml), Taxotere 80mg Konzentrat und Lösungsmittel zur Herstellung einer Infusionslösung, Taxotere 20mg Konzentrat und Lösungsmittel zur Herstellung einer Infusionslösung

An-Institut für Qualitätssicherung in der operativen Medizin gGmbH

lokal fortgeschrittenes Adenokarzinom des Magens oder des gastroösophagalen Übergangs