Neoplasm Metastasis  >>  oxaliplatin  >>  Phase 2
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62 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
oxaliplatin / Generic mfg.
NCT00865709 / 2008-005025-11: Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) Subjects

Checkmark Data-ESMO
Sep 2011 - Sep 2011: Data-ESMO
Completed
2b
198
US, Europe, RoW
Sorafenib (Nexavar, BAY43-9006) + mFOLFOX6 (5-FU, levo-leucovorin, oxaliplatin), Matching placebo + mFOLFOX6 (5-FU, levo-leucovorin, oxaliplatin)
Bayer, Amgen
Metastatic Colorectal Cancer
01/11
02/12
NCT00004127: Oxaliplatin Combined With Fluorouracil and Leucovorin in Treating Patients With Recurrent or Metastatic Cancer of the Esophagus or Stomach

Completed
2
35
US
FOLFOX regimen, fluorouracil, leucovorin calcium, oxaliplatin
University of Chicago, National Cancer Institute (NCI)
Esophageal Cancer, Gastric Cancer
10/02
08/03
NCT00065117: Safety, Tolerability and Efficacy of ZD6126 in Combination With Oxaliplatin, 5-Fluorouracil and Leucovorin in Subjects With Metastatic Colorectal Cancer.

Terminated
2
180
US
ZD6126, Placebo, 5-fluorouracil, leucovorin, oxaliplatin
AstraZeneca
Colorectal Neoplasms, Metastases, Neoplasm
02/04
02/04
NCT00070265: Neoadjuvant and Adjuvant Capecitabine and Oxaliplatin in Treating Patients With Resectable Liver Metastases Secondary to Colorectal Cancer

Terminated
2
80
US
oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, capecitabine, CAPE, Ro 09-1978/000, Xeloda, therapeutic conventional surgery, laboratory biomarker analysis
National Cancer Institute (NCI)
Liver Metastases, Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IV Colon Cancer, Stage IV Rectal Cancer
09/04
 
NCT00003834: Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

Completed
2
44
US, Canada
fluorouracil, leucovorin calcium, oxaliplatin
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Colorectal Cancer, Metastatic Cancer
12/05
12/05
NCT00026234: Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver

Completed
2
75
US
floxuridine, 5-FUDR, dexamethasone, Aeroseb-Dex, Decaderm, Decadron, DM, DXM, oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, capecitabine, CAPE, Ro 09-1978/000, Xeloda
National Cancer Institute (NCI), NSABP Foundation Inc
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Liver Metastases, Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IV Colon Cancer, Stage IV Rectal Cancer
01/06
 
NCT00120172: Study of Oxaliplatin, Capecitabine, and Bevacizumab to Treat Older Patients With Colorectal Cancer

Terminated
2
40
US
oxaliplatin, capecitabine, bevacizumab
Geriatric Oncology Consortium, Sanofi
Colorectal Cancer, Neoplasm Metastasis
 
06/06
NCT00103298: Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Completed
2
US
FOLFOX regimen, fluorouracil, isolated perfusion, leucovorin calcium, melphalan, oxaliplatin
National Cancer Institute (NCI)
Colorectal Cancer, Metastatic Cancer
 
07/06
NCT00123851: Tarceva, Capecitabine and Oxaliplatin for Metastatic Colorectal Cancer

Completed
2
32
US
Tarceva (OSI-774), Capecitabine, Oxaliplatin
Dana-Farber Cancer Institute, Sanofi-Synthelabo, OSI Pharmaceuticals, Hoffmann-La Roche, Genentech, Inc., Massachusetts General Hospital, Beth Israel Deaconess Medical Center
Colorectal Cancer, Neoplasm Metastasis
08/06
08/06
NCT00353145: Gemox as First and Second Line Therapy in Unknown Primary Cancer

Completed
2
29
US
Gemcitabine (Gemox), Gemcitabine Hydrochloride, Gemzar, Oxaliplatin, Eloxatin, Questionnaire
M.D. Anderson Cancer Center, Sanofi-Synthelabo
Unknown Primary Neoplasms
03/07
01/10
OPUS, NCT00125034: Oxaliplatin and Cetuximab in First-line Treatment of Metastatic Colorectal Cancer (mCRC)

Checkmark ASCO 2014
May 2014 - May 2014: ASCO 2014
Checkmark ASCO-GI 2014
Jan 2014 - Jan 2014: ASCO-GI 2014
Checkmark ASCO 2013
More
Completed
2
344
Europe, RoW
Cetuximab, Oxaliplatin
Merck KGaA, Darmstadt, Germany
Neoplasm Metastasis, Colorectal Cancer
03/07
11/10
NCT00118105: S0408: Capecitabine, Oxaliplatin, and Bevacizumab in Pts Undergoing Surgery for Liver Mets From Colorectal Cancer

Withdrawn
2
0
US
bevacizumab, Avastin, NSC-704865, capecitabine, Xeloda, NSC-712807, oxaliplatin, NSC-266046, conventional surgery
Southwest Oncology Group, National Cancer Institute (NCI), Eastern Cooperative Oncology Group
Colorectal Cancer, Metastatic Cancer
04/07
04/07
NCT00083616: Evaluating Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine, Irinotecan, and Oxaliplatin Chemotherapy

Completed
2
185
US
Panitumumab, ABX-EGF, Vectibix
Amgen
Colorectal Cancer, Metastatic Cancer
05/07
12/08
NCT00346099: Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum

Withdrawn
2
0
US
Panitumumab with capecitabine and oxaliplatin (CAPOX) followed by, Panitumumab with capecitabine and radiation
NSABP Foundation Inc, Amgen
Rectal Cancer, Neoplasm Metastasis
 
05/07
NCT00043004: Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer

Terminated
2
119
Europe, RoW
bevacizumab, FOLFOX regimen, fluorouracil, leucovorin calcium, oxaliplatin, conventional surgery, radiofrequency ablation
European Organisation for Research and Treatment of Cancer - EORTC, Arbeitsgruppe Lebermetastasen und Tumoren, Institute of Cancer Research, United Kingdom
Colorectal Cancer, Metastatic Cancer
06/07
 
NCT00056030: Combination Chemotherapy Plus Cetuximab in Treating Patients With Liver Metastases From Colorectal Cancer

Completed
2
73
US
cetuximab, fluorouracil, leucovorin calcium, oxaliplatin
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Colorectal Cancer, Metastatic Cancer
10/07
 
NCT00305786: Gemcitabine and Oxaliplatin as Second-Line Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Completed
2
30
US
gemcitabine hydrochloride, oxaliplatin
University of Miami
Lung Cancer
12/07
05/10
NCT00153998: Cetuximab in Neoadjuvant Treatment of Non-Resectable Colorectal Liver Metastases (CELIM)

Checkmark
Mar 2014 - Mar 2014: 
Checkmark ESMO 2013
Sep 2013 - Sep 2013: ESMO 2013
Checkmark ASCO 2013
More
Completed
2
135
Europe
Cetuximab, Liver resection, Cetuximab and FOLFIRI, Cetuximab(C225, Erbitux®, Merck KGaA), Irinotecan (irinotecan HCl, CPT-11 or Campto®, Aventis), 5-Fluorouracil (5-FU), Folinic acid (FA, i.e. Leucovorin®, Wyeth), Cetuximab and FOLFOX, Oxaliplatin (L-OHP, Eloxatin®, Sanofi-Synthelabo)
Technische Universität Dresden
Colorectal Cancer, Liver Metastases
03/08
 
NCT00193609: Oxaliplatin and Capecitabine in the Treatment of Relapsed/Refractory Carcinoma of Unknown Primary Site

Completed
2
48
US
Oxaliplatin, Eloxatin, Capecitabine, Xeloda
SCRI Development Innovations, LLC, Roche Pharma AG, Sanofi-Synthelabo
Neoplasms, Unknown Primary
04/08
01/09
NCT00408772: Oxaliplatin, Capecitabine, and Bevacizumab Followed By Surgery and/or Radiofrequency Ablation in Patients With Colorectal Cancer

Withdrawn
2
0
US
bevacizumab, capecitabine, oxaliplatin, conventional surgery, neoadjuvant therapy, radiofrequency ablation
University of California, Davis, Sanofi
Colorectal Cancer, Metastatic Cancer
04/08
04/08
NCT00508872: Folfox-B Study for Patients With Colorectal Liver Metastases

Terminated
2
2
US
5-Fluorouracil, 5-FU, Adrucil, Efudex, Bevacizumab, Avastin, Anti-VEGF monoclonal antibody, rhuMAb-VEGF, Leucovorin, Citrovorum, Wellcovorin, Oxaliplatin, Eloxatin
M.D. Anderson Cancer Center, Sanofi
Colorectal Liver Metastases
06/09
06/09
TIROX2, NCT00512681: A Phase II Study of Irinotecan, Oxaliplatin, Plus TS-1 in Untreated Metastatic Gastric Cancer

Completed
2
44
RoW
Irinotecan, Oxaliplatin, TS-1
National Cancer Center, Korea
Stomach Neoplasms
07/09
07/09
NCT00557206: Oxaliplatin and Docetaxel for Recurrent or Metastatic Head and Neck Cancer

Terminated
2
35
US
Oxaliplatin and Docetaxel
Minneapolis Veterans Affairs Medical Center, Sanofi
Neoplasms, Head and Neck Neoplasms
11/09
11/09
NCT00537823: Pre- and Post-operative FOLFOX Based Therapy for Patients With Colorectal Cancer With Liver Involvement

Terminated
2
9
US
Cetuximab, Erbitux, Bevacizumab, Avastin, Leucovorin, Oxaliplatin, Fluorouracil
Washington University School of Medicine
Colorectal Cancer, Metastases
12/09
07/11
NCT01022541 / 2005-004505-29: Capecitabine and Oxaliplatin Plus Bevacizumab as Neoadjuvant Treatment for Untreated Unresectable Liver-only Metastases From Colorectal Cancer

Checkmark P2 data-BOXER
Apr 2012 - Apr 2012: P2 data-BOXER
Checkmark P2 data (CRC)
Dec 2011 - Dec 2011: P2 data (CRC)
Completed
2
47
Europe
Capecitabine, Xeloda, Oxaliplatin, Eloxatin, Bevacizumab, Avastin, Liver metastasectomy
Royal Marsden NHS Foundation Trust, Roche Pharma AG
Metastatic Colorectal Cancer
12/10
02/15
HEARTO, NCT01348412: Hepatic Arterial Chemotherapy With Raltitrexed and Oxaliplatin Versus Standard Chemotherapy in Unresectable Liver Metastases From Colorectal Cancer After Conventional Chemotherapy Failure

Completed
2
31
Europe
oxaliplatin, raltitrexed, other intravenous chemotherapy drugs
Centre Georges Francois Leclerc, National Cancer Institute, France, Hospira, now a wholly owned subsidiary of Pfizer
Colorectal Cancer, Liver Metastases
12/10
04/18
APRIORI, NCT01126866: Curative Resectability of Not Optimally Resectable Liver and/or Lung Metastases From Colorectal Carcinoma (CRC) Under Intensified Chemotherapy

Terminated
2
35
Europe
intensified chemotherapy (FOLFOXIRI/Bevacizumab)
National Center for Tumor Diseases, Heidelberg, Roche Pharma AG, Pfizer
Colorectal Carcinoma
03/11
06/11
AFFIRM, NCT00851084 / 2008-004178-41: Study of Aflibercept And Modified FOLFOX6 As First-Line Treatment In Patients With Metastatic Colorectal Cancer

Checkmark P2 data-ESMO-GI
Jun 2012 - Jun 2012: P2 data-ESMO-GI
Completed
2
268
Europe, RoW
aflibercept, ZALTRAP™, AVE0005, oxaliplatin, 5-FU, Folinic Acid
Sanofi
Colorectal Neoplasms, Neoplasm Metastasis
04/11
01/12
NCT00544349: Leucovorin, Fluorouracil, Cetuximab, and Oxaliplatin in Treating Patients With Stage IV Colorectal Cancer and Liver Metastases That Cannot Be Removed by Surgery

Checkmark P2 data - ESMO
Sep 2012 - Sep 2012: P2 data - ESMO
Completed
2
45
Europe
cetuximab, fluorouracil, leucovorin calcium, oxaliplatin
Gustave Roussy, Cancer Campus, Grand Paris
Colorectal Cancer, Metastatic Cancer
05/11
 
NCT00700570: A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Colorectal Cancer

Completed
2
45
RoW
bevacizumab [Avastin], capecitabine [Xeloda], oxaliplatin
Hoffmann-La Roche
Colorectal Cancer
11/11
11/11
NCT00743678: Neoadjuvant FOLFOX6 + Cetuximab in Patients With Colorectal Cancer and Unresectable Liver Metastasis

Completed
2
73
RoW
FOLFOX6/cetuximab
Samsung Medical Center
Colorectal Cancer, Unresectable Liver Metastasis
01/12
06/12
NCT01293942: IXO+A in mCRC With Liver-only Metastases

Withdrawn
2
0
Canada
irinotecan, capecitabine, oxaliplatin (IXO) and bevacizumab
Ottawa Hospital Research Institute, Hoffmann-La Roche, Sanofi
Metastatic Colorectal Cancer
02/12
02/12
NCT00890305 / 2009-014593-18: Study to Evaluate the Safety, Tolerability and Efficacy of FOLFOX + CT-011 Versus FOLFOX Alone

Checkmark mCRC
Nov 2013 - Nov 2013: mCRC
Completed
2
171
US, Europe, RoW
CT-011, FOLFOX
Medivation, Inc.
Metastatic Colorectal Cancer
05/12
03/13
NCT01157039: A Trial of Glutamine to Prevent Oxaliplatin Neurotoxicity and a Pharmacokinetic Analysis of Oxaliplatin

Withdrawn
2
0
Canada
Glutamine, L-glutamine
AHS Cancer Control Alberta, Cross Cancer Institute
Colorectal Carcinoma, Neoplasms, Colorectal, Colorectal Cancer, Colorectal Tumors, Metastasis
09/12
 
NCT01703910 / 2012-001307-20: Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic

Completed
2
29
Europe
Arm A chemotherapy, Capecitabine, Cisplatin, Cetuximab, Doxorubicin, Fluorouracil, Gemcitabine, Irinotecan, Topotecan, Mitomycin C, Oxaliplatin, Paclitaxel, Docetaxel, Pemetrexed, Raltitrexed, Sorafenib, Erlotinib, Vinorelbine, Dasatinib, Etoposide, arm B chemotherapy
Centro Nacional de Investigaciones Oncologicas CARLOS III, Hospital Universitario de Fuenlabrada, Grupo Hospital de Madrid, Apices Soluciones S.L.
Adenocarcinoma of Colon, Adenocarcinoma of Rectum, Metastatic Disease
11/12
12/14
NCT02071043: Trial of Xeloda and Oxaliplatin (XELOX) as Neo-adjuvant Chemotherapy Followed by Surgery in Advanced Gastric Cancer Patients With Para-aortic Lymph Node Metastasis

Completed
2
48
RoW
Capecitabine, Oxaliplatin
Shanghai Zhongshan Hospital
Advanced Gastric Cancer
01/13
01/13
PERIMAX, NCT01540435 / 2010-023575-25: Perioperative Treatment of Resectable Liver Metastases

Withdrawn
2
0
Europe
Bevacizumab, VEGF antibody
University of Regensburg, University of Halle Medical Faculty
Colon Cancer Liver Metastasis
05/13
05/13
OLIVIA, NCT00778102 / 2007-007863-26: A Study of Avastin (Bevacizumab) in Combination With mFOLFOX-6 or FOLFOXIRI in Patients With Metastatic Colorectal Cancer.

Checkmark ESMO-ECCO-ESTRO 2013
Sep 2013 - Sep 2013: ESMO-ECCO-ESTRO 2013
Completed
2
80
Europe
5-FU, Irinotecan, Leucovorin, Oxaliplatin, bevacizumab [Avastin]
Hoffmann-La Roche
Colorectal Cancer
10/13
10/13
HerXO, NCT01503983 / 2011-001231-23: Efficacy and Safety of Trastuzumab, Capecitabine y Oxaliplatine as Treatment Gastric Cancer Metastatic (HER2)Positive

Completed
2
45
Europe
Trastuzumab, Herceptin, Capecitabine, Xeloda, Oxaliplatin, Oxaliplatino
Fundación para el Progreso de la Oncología en Cantabria
Stage IV Gastric Cancer With Metastasis
12/13
05/15
NCT02345746: Hepatic Arterial Infusion With FOLFOX Alone or in Combination With IV Chemotherapy in Colon Cancer With Liver Metastasis

Withdrawn
2
0
NA
Oxaliplatin, Eloxatin®, Folinic Acid, Leucovorin, 5-Fluorouracil, 5-FU
Western Regional Medical Center
Metastatic Colorectal Cancer
12/13
12/13
XAGastric, NCT00447330: Oxaliplatin, Capecitabine and Avastin for Metastatic Esophagogastric Adenocarcinoma

Checkmark capecitabine, oxaliplatin, and bevacizumab in met esophagogastric adenocarcinomas
Mar 2013 - Mar 2013: capecitabine, oxaliplatin, and bevacizumab in met esophagogastric adenocarcinomas
Completed
2
60
US
capecitabine (Xeloda), oxaliplatin and bevacizumab (Avastin)
Duke University, Hoffmann-La Roche, Sanofi, Genentech, Inc.
Esophageal Neoplasms, Stomach Neoplasms, Neoplasm Metastasis
01/14
07/14
NCT01226719: FOLFOXIRI Plus Panitumumab Patients With Metastatic KRAS Wild-Type Colorectal Cancer With Liver Metastases Only

Checkmark ASCO 2014
May 2014 - May 2014: ASCO 2014
Completed
2
15
US
Panitumumab, Combined Modality Treatment, Oxaliplatin, Irinotecan, Leucovorin, 5-Fluorouracil
SCRI Development Innovations, LLC, Amgen
Colorectal Cancer
03/14
03/14
NCT01383707 / 2011-001364-22: A Study of Bevacizumab and Modified FOLFOX-6 (mFOLFOX-6) in Participants With Metastatic Colorectal Cancer

Completed
2
77
Europe
5-Fluorouracil (5-FU), Bevacizumab, Avastin, Levofolinic acid, Oxaliplatin
Hoffmann-La Roche
Colorectal Cancer
05/14
05/16
PRIMM, NCT01715363: Feasibility of an Immediate Preoperative Chemotherapy Before Resection fo Colorectal Cancer

Terminated
2
3
Europe
Oxaliplatin, Folinic Acid, Fluorouracile
Gustave Roussy, Cancer Campus, Grand Paris
Patients With Colorectal Cancer With Unresectable Synchronous Metastasis in Whom Resection of the Primitive Tumour is Indicated
06/14
06/14
NCT01937507: Hepatic Artery Infusion With FOLFOX in Liver Metastasis From Breast Cancer

Terminated
2
2
US
HAI with FOLFOX, Hepatic Artery Infusion
Western Regional Medical Center
Metastatic Breast Cancer
07/14
07/14
NCT01320683: Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Terminated
2
1
US
oxaliplatin, 1-OHP, Dacotin, Dacplat, Eloxatin, L-OHP, leucovorin calcium, CF, CFR, LV, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, bevacizumab, anti-VEGF humanized monoclonal antibody, anti-VEGF monoclonal antibody, Avastin, rhuMAb VEGF, yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A, laboratory biomarker analysis, pharmacological study, pharmacological studies, irinotecan hydrochloride, Campto, Camptosar, CPT-11, irinotecan, U-101440E
City of Hope Medical Center, National Cancer Institute (NCI)
Liver Metastases, Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer
12/14
12/14
PLANET, NCT00885885 / 2008-006766-28: Safety and Efficacy Study of FOLFOX4+Panitumumab vs.FOLFIRI+Panitumumab in Subjects WT KRAS Colorectal Cancer and Liver-only Metastases

Checkmark ECC 2015
Sep 2015 - Sep 2015: ECC 2015
Checkmark ESMO 2014
Sep 2014 - Sep 2014: ESMO 2014
Checkmark ESMO WCGI 2014
More
Completed
2
80
Europe
Panitumumab+FOLFOX-4, Panitumumab+FOLFIRI
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD), Amgen
Colorectal Cancer
03/15
03/15
NCT01269229: A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis

Completed
2
32
RoW
folfox, short course Radiotherapy
Yonsei University
Rectal Cancer
04/15
04/15
NCT01858662 / 2012-005249-19: Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors

Terminated
2
4
Europe
Metastases Resection ( multiple steep surgery possible), 5-Fluorouracile, 5FU, leucovorin L, elvorine, isovorin, Oxaliplatin, Eloxatin, Irinotecan, Campto, Irinosin, Cetuximab, erbitux
Cliniques universitaires Saint-Luc- Université Catholique de Louvain, Grand Hôpital de Charleroi
Metastatic Colorectal Cancer
11/15
11/15
NCT01581307: Phase II Trial Evaluating OS With Therasphere® + 2nd-Line FOLFOX in Pancreatic Liver Mets

Completed
2
9
US
FOLFOX7 (Folinic acid, 5-Fluorouracil, and Oxaliplatin), Leucovorin, LV, FOL, OX, 5-Fluorouracil (5-FU), FOLFOX, ELOXATIN, TheraSpheres, radiotherapy, radioembolization
H. Lee Moffitt Cancer Center and Research Institute, BTG International Inc.
Liver Cancer, Pancreatic Cancer
02/16
03/16
BEVIAC, NCT01677884: Intra-arterial Hepatic Bevacizumab and Systemic Chemotherapy

Checkmark ASCO 2016
May 2016 - May 2016: ASCO 2016
Completed
2
10
Europe
Bevacizumab, Capecitabine, Irinotecan
Gustave Roussy, Cancer Campus, Grand Paris
Colorectal Neoplasms
02/16
02/16
PREVIUM, NCT02175654 / 2014-000703-26: Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab

Terminated
2
15
Europe
Regorafenib
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD), Bayer
Colorectal Neoplasms, Metastatic Disease
02/16
02/16
BOS2, NCT01508000 / 2010-019238-29: Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver Metastases

Checkmark For wild-type RAS mutant 1st-line mCRC
Jun 2013 - Jun 2013: For wild-type RAS mutant 1st-line mCRC
Terminated
2
44
Europe
FOLFOX6, Chemotherapy, Bevacizumab, Avastin, Panitumumab, Vectibix, Surgery
European Organisation for Research and Treatment of Cancer - EORTC, Amgen, Roche Pharma AG
Colorectal Cancer Metastatic, Liver Metastases, KRAS Wild Type Colorectal Cancer
09/16
09/16
ATOM, NCT01836653: Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases

Completed
2
122
Japan
Bevacizumab, Avastin, Cetuximab, Erbitux, L-OHP, Oxaliplatin, l-LV, Levofolinate, 5-FU, Fluorouracil
EPS Corporation
Liver Only Metastasis From KRAS Exon 2 Wild Type (Under Protocol 1.0-1.2 Edition) and RAS Wild Type (Under Protocol 2.0 Edition) Colorectal Cancer
03/17
03/17
NCT02015169: Phase II Study of Neoadjuvant XELOX + Lapatinib in HER2(+) Gastric Cancer Patients With Liver Metastasis

Completed
2
32
RoW
Lapatinib, Tykerb, GSK
Samsung Medical Center
HER2-positive Gastric Cancer Patients With Liver Metastasis
07/17
11/17
VISNU-2, NCT01640444 / 2012-000840-90: Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC)

Completed
2
240
Europe
FOLFIRI + bevacizumab, FOLFIRI + cetuximab
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD), Roche Pharma AG
Colorectal Cancer Metastatic
11/18
11/18
NCT00494221: A Phase I/II Study of Cediranib (AZD2171) in Japanese Metastatic Colorectal Cancer Patients in Combination With FOLFOX

Checkmark Data
Aug 2011 - Aug 2011: Data
Completed
1/2
172
Japan
AZD2171, cediranib, RECENTIN™, FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin), Eloxatin®, 5-FU, Leucovorin, Placebo Cediranib
AstraZeneca
Metastatic Colorectal Cancer
10/09
08/12
NCT00228189: Carcinoembryonic Antigen-loaded Dendritic Cells in Advanced Colorectal Cancer Patients

Completed
1/2
30
Europe
CEA-loaded dendritic cell vaccine
Radboud University Medical Center
Colorectal Cancer, Liver Metastases
11/10
11/10
NCT02048540: Neoadjuvant Bev Plus DOF vs DOF in LAGC and Its Association With Circulating Tumor Cell

Completed
1/2
86
RoW
Bevacizumab, docetaxel oxaliplatin 5-FU CF, Gastrectomy
Chinese PLA General Hospital
Locally Advanced Gastric Carcinoma
12/13
12/13
NCT01632306: A Study of LY2090314 and Chemotherapy in Participants With Metastatic Pancreatic Cancer

Terminated
1/2
13
US
LY2090314, FOLFOX, FOLFOX (leucovorin + 5-fluorouracil + oxaliplatin), Gemcitabine, Gemzar, LY188011, Nab-paclitaxel
Eli Lilly and Company, Mayo Clinic
Pancreatic Cancer
06/15
06/15
ACTION, NCT02273713: The Addition of Nab-paclitaxel (Abraxane) to First Line Treatment of Metastasized Oesophagogastric Carcinoma

Completed
1/2
154
Europe
Nab-paclitaxel, Abraxane
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Celgene Corporation
Esophageal Cancer, Toxicity
03/17
03/17
NCT01206530: FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

Completed
1/2
50
US
Hydroxychloroquine, Oxaliplatin, Leucovorin, 5-fluorouracil, Bevacizumab
Abramson Cancer Center of the University of Pennsylvania
Rectal Cancer, Colon Cancer, Metastasis, Adenocarcinoma
09/17
09/17

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